Identification of the xenosensors regulating human 5-aminolevulinate synthase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 24, 2004, Pages 9127-9132

  Podvinec, Michael ^a   Handschin, Christoph ^a,b   Looser, Renate ^a   Meyer, Urs A ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 ISOPROPYLVALERAMIDE; 5 AMINOLEVULINATE SYNTHASE; ANDROSTANE DERIVATIVE; ANDROSTANE RECEPTOR; APOPROTEIN; CYTOCHROME P450; DRUG METABOLIZING ENZYME; GLUTETHIMIDE; HEME; HEMOPROTEIN; METYRAPONE; PHENOBARBITAL; PREGNANE X RECEPTOR; RECEPTOR; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

ALAS1 GENE; ANIMAL CELL; ARTICLE; BIOSENSOR; COMPUTER MODEL; CONTROLLED STUDY; DNA RESPONSIVE ELEMENT; DRUG EXPOSURE; DRUG RESPONSE; DRUG TRANSFORMATION; ENERGY METABOLISM; ENHANCER REGION; ENZYME INDUCTION; ENZYME REGULATION; GENE; GENE ACTIVATION; GENE INDUCTION; GENETIC TRANSCRIPTION; HEME SYNTHESIS; HEPATIC PORPHYRIA; IN VITRO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; TRANSCRIPTION INITIATION SITE; XENOSENSOR;

5' FLANKING REGION; 5-AMINOLEVULINATE SYNTHETASE; BASE SEQUENCE; CELL LINE; ENHANCER ELEMENTS (GENETICS); ENZYME INDUCTION; HUMANS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; XENOBIOTICS;

ANIMALIA;

EID: 2942672077     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0401845101     Document Type: Article

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