메뉴 건너뛰기




Volumn 25, Issue 5, 2014, Pages 263-273

Maternal choline supplementation: A nutritional approach for improving offspring health?

Author keywords

Choline; Development; Epigenetics; Fetus; Programming

Indexed keywords

CHOLINE;

EID: 84899480779     PISSN: 10432760     EISSN: 18793061     Source Type: Journal    
DOI: 10.1016/j.tem.2014.02.001     Document Type: Review
Times cited : (86)

References (101)
  • 1
    • 84995896997 scopus 로고    scopus 로고
    • Choline
    • Taylor Francis LLC, J. Zempleni (Ed.)
    • Jiang X., et al. Choline. Handbook of Vitamins 2013, 492-508. Taylor Francis LLC. 5th edn. J. Zempleni (Ed.).
    • (2013) Handbook of Vitamins , pp. 492-508
    • Jiang, X.1
  • 2
    • 77955046460 scopus 로고    scopus 로고
    • Pre- and postnatal health: evidence of increased choline needs
    • Caudill M.A. Pre- and postnatal health: evidence of increased choline needs. J. Am. Diet. Assoc. 2010, 110:1198-1206.
    • (2010) J. Am. Diet. Assoc. , vol.110 , pp. 1198-1206
    • Caudill, M.A.1
  • 3
    • 0042519597 scopus 로고    scopus 로고
    • Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan
    • Meck W.H., Williams C.L. Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan. Neurosci. Biobehav. Rev. 2003, 27:385-399.
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 385-399
    • Meck, W.H.1    Williams, C.L.2
  • 4
    • 0030740487 scopus 로고    scopus 로고
    • Human placental cholinergic system
    • Sastry B.V. Human placental cholinergic system. Biochem. Pharmacol. 1997, 53:1577-1586.
    • (1997) Biochem. Pharmacol. , vol.53 , pp. 1577-1586
    • Sastry, B.V.1
  • 5
    • 75149164375 scopus 로고    scopus 로고
    • Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene
    • Mehedint M.G., et al. Choline deficiency alters global histone methylation and epigenetic marking at the Re1 site of the calbindin 1 gene. FASEB J. 2010, 24:184-195.
    • (2010) FASEB J. , vol.24 , pp. 184-195
    • Mehedint, M.G.1
  • 6
    • 77955635459 scopus 로고    scopus 로고
    • Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus
    • Mehedint M.G., et al. Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:12834-12839.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 12834-12839
    • Mehedint, M.G.1
  • 7
    • 30744479491 scopus 로고    scopus 로고
    • Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains
    • Niculescu M.D., et al. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J. 2006, 20:43-49.
    • (2006) FASEB J. , vol.20 , pp. 43-49
    • Niculescu, M.D.1
  • 8
    • 35748965898 scopus 로고    scopus 로고
    • Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression
    • Kovacheva V.P., et al. Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of Dnmt1 expression. J. Biol. Chem. 2007, 282:31777-31788.
    • (2007) J. Biol. Chem. , vol.282 , pp. 31777-31788
    • Kovacheva, V.P.1
  • 9
    • 65349097911 scopus 로고    scopus 로고
    • Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival
    • Kovacheva V.P., et al. Raising gestational choline intake alters gene expression in DMBA-evoked mammary tumors and prolongs survival. FASEB J. 2009, 23:1054-1063.
    • (2009) FASEB J. , vol.23 , pp. 1054-1063
    • Kovacheva, V.P.1
  • 10
    • 59049105953 scopus 로고    scopus 로고
    • Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain
    • Davison J.M., et al. Gestational choline supply regulates methylation of histone H3, expression of histone methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA methylation of their genes in rat fetal liver and brain. J. Biol. Chem. 2009, 284:1982-1989.
    • (2009) J. Biol. Chem. , vol.284 , pp. 1982-1989
    • Davison, J.M.1
  • 11
    • 84874194072 scopus 로고    scopus 로고
    • DNA methylation: roles in mammalian development
    • Smith Z.D., Meissner A. DNA methylation: roles in mammalian development. Nat. Rev. Genet. 2013, 14:204-220.
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 204-220
    • Smith, Z.D.1    Meissner, A.2
  • 12
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: targets for early nutritional effects on epigenetic gene regulation
    • Waterland R.A., Jirtle R.L. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol. Cell. Biol. 2003, 23:5293-5300.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 13
    • 55949137722 scopus 로고    scopus 로고
    • Persistent epigenetic differences associated with prenatal exposure to famine in humans
    • Heijmans B.T., et al. Persistent epigenetic differences associated with prenatal exposure to famine in humans. Proc. Natl. Acad. Sci. U.S.A. 2008, 105:17046-17049.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 17046-17049
    • Heijmans, B.T.1
  • 14
    • 20444411948 scopus 로고    scopus 로고
    • Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
    • Lillycrop K.A., et al. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J. Nutr. 2005, 135:1382-1386.
    • (2005) J. Nutr. , vol.135 , pp. 1382-1386
    • Lillycrop, K.A.1
  • 15
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • Oberlander T.F., et al. Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses. Epigenetics 2008, 3:97-106.
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1
  • 16
    • 78650688321 scopus 로고    scopus 로고
    • Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles
    • Waterland R.A., et al. Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles. PLoS Genet. 2010, 6:e1001252.
    • (2010) PLoS Genet. , vol.6
    • Waterland, R.A.1
  • 17
    • 34548715144 scopus 로고    scopus 로고
    • Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development
    • Dolinoy D.C., et al. Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:13056-13061.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 13056-13061
    • Dolinoy, D.C.1
  • 18
    • 69949103740 scopus 로고    scopus 로고
    • Influence of prenatal lead exposure on genomic methylation of cord blood DNA
    • Pilsner J.R., et al. Influence of prenatal lead exposure on genomic methylation of cord blood DNA. Environ. Health Perspect. 2009, 117:1466-1471.
    • (2009) Environ. Health Perspect. , vol.117 , pp. 1466-1471
    • Pilsner, J.R.1
  • 19
    • 77954107743 scopus 로고    scopus 로고
    • Effects of arsenic exposure on DNA methylation and epigenetic gene regulation
    • Reichard J.F., Puga A. Effects of arsenic exposure on DNA methylation and epigenetic gene regulation. Epigenomics 2010, 2:87-104.
    • (2010) Epigenomics , vol.2 , pp. 87-104
    • Reichard, J.F.1    Puga, A.2
  • 20
    • 33751533712 scopus 로고    scopus 로고
    • Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease
    • Anway M.D., et al. Endocrine disruptor vinclozolin induced epigenetic transgenerational adult-onset disease. Endocrinology 2006, 147:5515-5523.
    • (2006) Endocrinology , vol.147 , pp. 5515-5523
    • Anway, M.D.1
  • 21
    • 84864597488 scopus 로고    scopus 로고
    • Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations
    • Govorko D., et al. Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. Biol. Psychiatry 2012, 72:378-388.
    • (2012) Biol. Psychiatry , vol.72 , pp. 378-388
    • Govorko, D.1
  • 22
    • 81055136672 scopus 로고    scopus 로고
    • Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression
    • Suter M., et al. Maternal tobacco use modestly alters correlated epigenome-wide placental DNA methylation and gene expression. Epigenetics 2011, 6:1284-1294.
    • (2011) Epigenetics , vol.6 , pp. 1284-1294
    • Suter, M.1
  • 23
    • 0036862451 scopus 로고    scopus 로고
    • Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
    • Kaati G., et al. Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period. Eur. J. Hum. Genet. 2002, 10:682-688.
    • (2002) Eur. J. Hum. Genet. , vol.10 , pp. 682-688
    • Kaati, G.1
  • 24
    • 0033926263 scopus 로고    scopus 로고
    • Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes, and hypertension in adult men and women
    • Osmond C., Barker D.J. Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes, and hypertension in adult men and women. Environ. Health Perspect. 2000, 108(Suppl. 3):545-553.
    • (2000) Environ. Health Perspect. , vol.108 , Issue.SUPPL. 3 , pp. 545-553
    • Osmond, C.1    Barker, D.J.2
  • 25
    • 60149112073 scopus 로고    scopus 로고
    • A fingerprint marker from early gestation associated with diabetes in middle age: the Dutch Hunger Winter Families Study
    • Kahn H.S., et al. A fingerprint marker from early gestation associated with diabetes in middle age: the Dutch Hunger Winter Families Study. Int. J. Epidemiol. 2009, 38:101-109.
    • (2009) Int. J. Epidemiol. , vol.38 , pp. 101-109
    • Kahn, H.S.1
  • 26
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch R., Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 2003, 33(Suppl.):245-254.
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 27
    • 84866154375 scopus 로고    scopus 로고
    • Fetal programming of the neuroendocrine-immune system and metabolic disease
    • Fisher R.E., et al. Fetal programming of the neuroendocrine-immune system and metabolic disease. J. Pregnancy 2012, 2012:792934.
    • (2012) J. Pregnancy , vol.2012 , pp. 792934
    • Fisher, R.E.1
  • 28
    • 0034928759 scopus 로고    scopus 로고
    • Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations
    • Meaney M.J. Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations. Annu. Rev. Neurosci. 2001, 24:1161-1192.
    • (2001) Annu. Rev. Neurosci. , vol.24 , pp. 1161-1192
    • Meaney, M.J.1
  • 29
    • 78650450565 scopus 로고    scopus 로고
    • A methyl-deficient diet fed to rat dams during the peri-conception period programs glucose homeostasis in adult male but not female offspring
    • Maloney C.A., et al. A methyl-deficient diet fed to rat dams during the peri-conception period programs glucose homeostasis in adult male but not female offspring. J. Nutr. 2011, 141:95-100.
    • (2011) J. Nutr. , vol.141 , pp. 95-100
    • Maloney, C.A.1
  • 30
    • 37649011327 scopus 로고    scopus 로고
    • DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status
    • Sinclair K.D., et al. DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:19351-19356.
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 19351-19356
    • Sinclair, K.D.1
  • 31
    • 84873036238 scopus 로고    scopus 로고
    • Sex differences in developmental programming models
    • Aiken C.E., Ozanne S.E. Sex differences in developmental programming models. Reproduction 2013, 145:R1-R13.
    • (2013) Reproduction , vol.145
    • Aiken, C.E.1    Ozanne, S.E.2
  • 32
    • 84864772359 scopus 로고    scopus 로고
    • Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans
    • Jiang X., et al. Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans. FASEB J. 2012, 26:3563-3574.
    • (2012) FASEB J. , vol.26 , pp. 3563-3574
    • Jiang, X.1
  • 33
    • 34547782307 scopus 로고    scopus 로고
    • Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes
    • Resseguie M., et al. Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J. 2007, 21:2622-2632.
    • (2007) FASEB J. , vol.21 , pp. 2622-2632
    • Resseguie, M.1
  • 34
    • 0028868418 scopus 로고
    • Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver
    • Zeisel S.H., et al. Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver. J. Nutr. 1995, 125:3049-3054.
    • (1995) J. Nutr. , vol.125 , pp. 3049-3054
    • Zeisel, S.H.1
  • 35
    • 84860267035 scopus 로고    scopus 로고
    • Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
    • Yan J., et al. Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans. Am. J. Clin. Nutr. 2012, 95:1060-1071.
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 1060-1071
    • Yan, J.1
  • 36
    • 0031718956 scopus 로고    scopus 로고
    • Antioxidant transport by the human placenta
    • Schenker S., et al. Antioxidant transport by the human placenta. Clin. Nutr. 1998, 17:159-167.
    • (1998) Clin. Nutr. , vol.17 , pp. 159-167
    • Schenker, S.1
  • 37
    • 84880372266 scopus 로고    scopus 로고
    • L-methionine placental uptake: characterization and modulation in gestational diabetes mellitus
    • Araújo J.R., et al. L-methionine placental uptake: characterization and modulation in gestational diabetes mellitus. Reprod. Sci. 2013, 20:1492-1507.
    • (2013) Reprod. Sci. , vol.20 , pp. 1492-1507
    • Araújo, J.R.1
  • 38
    • 84874637515 scopus 로고    scopus 로고
    • A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1)
    • Jiang X., et al. A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1). FASEB J. 2013, 27:1245-1253.
    • (2013) FASEB J. , vol.27 , pp. 1245-1253
    • Jiang, X.1
  • 39
    • 27744606487 scopus 로고    scopus 로고
    • Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery
    • Molloy A.M., et al. Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery. Am. J. Clin. Nutr. 2005, 82:836-842.
    • (2005) Am. J. Clin. Nutr. , vol.82 , pp. 836-842
    • Molloy, A.M.1
  • 40
    • 21944433018 scopus 로고    scopus 로고
    • Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy
    • Velzing-Aarts F.V., et al. Plasma choline and betaine and their relation to plasma homocysteine in normal pregnancy. Am. J. Clin. Nutr. 2005, 81:1383-1389.
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 1383-1389
    • Velzing-Aarts, F.V.1
  • 41
    • 84888270619 scopus 로고    scopus 로고
    • Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women
    • Yan J., et al. Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women. Am. J. Clin. Nutr. 2013, 98:1459-1467.
    • (2013) Am. J. Clin. Nutr. , vol.98 , pp. 1459-1467
    • Yan, J.1
  • 42
    • 77955042574 scopus 로고    scopus 로고
    • Folate and choline interrelationships
    • CRC Press, L.B. Bailey (Ed.)
    • Caudill M.A. Folate and choline interrelationships. Folate in Health and Disease 2010, 449-466. CRC Press. 2nd edn. L.B. Bailey (Ed.).
    • (2010) Folate in Health and Disease , pp. 449-466
    • Caudill, M.A.1
  • 43
    • 75149133711 scopus 로고    scopus 로고
    • Choline in the diets of the US population: NHANES, 2003-2004
    • Jensen H., et al. Choline in the diets of the US population: NHANES, 2003-2004. FASEB J. 2007, 21:lb219.
    • (2007) FASEB J. , vol.21
    • Jensen, H.1
  • 44
    • 84933679118 scopus 로고    scopus 로고
    • The role of nutrition in children's neurocognitive development, from pregnancy through childhood
    • Nyaradi A., et al. The role of nutrition in children's neurocognitive development, from pregnancy through childhood. Front. Hum. Neurosci. 2013, 7:97.
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 97
    • Nyaradi, A.1
  • 45
    • 70349157245 scopus 로고    scopus 로고
    • Fetal origins of mental health: evidence and mechanisms
    • Schlotz W., Phillips D.I.W. Fetal origins of mental health: evidence and mechanisms. Brain Behav. Immun. 2009, 23:905-916.
    • (2009) Brain Behav. Immun. , vol.23 , pp. 905-916
    • Schlotz, W.1    Phillips, D.I.W.2
  • 46
    • 33747837807 scopus 로고    scopus 로고
    • An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring
    • McCann J.C., et al. An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring. Neurosci. Biobehav. Rev. 2006, 30:696-712.
    • (2006) Neurosci. Biobehav. Rev. , vol.30 , pp. 696-712
    • McCann, J.C.1
  • 47
    • 17144464513 scopus 로고    scopus 로고
    • Prenatal choline supplementation protects against postnatal neurotoxicity
    • Guo-Ross S.X., et al. Prenatal choline supplementation protects against postnatal neurotoxicity. J. Neurosci. 2002, 22:RC195.
    • (2002) J. Neurosci. , vol.22
    • Guo-Ross, S.X.1
  • 48
    • 0034668871 scopus 로고    scopus 로고
    • Protective effects of prenatal choline supplementation on seizure-induced memory impairment
    • Yang Y., et al. Protective effects of prenatal choline supplementation on seizure-induced memory impairment. J. Neurosci. 2000, 20:RC109.
    • (2000) J. Neurosci. , vol.20
    • Yang, Y.1
  • 49
    • 42649113725 scopus 로고    scopus 로고
    • Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus
    • Wong-Goodrich S.J.E., et al. Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus. Neurobiol. Dis. 2008, 30:255-269.
    • (2008) Neurobiol. Dis. , vol.30 , pp. 255-269
    • Wong-Goodrich, S.J.E.1
  • 50
    • 79956372210 scopus 로고    scopus 로고
    • Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood
    • Wong-Goodrich S.J.E., et al. Water maze experience and prenatal choline supplementation differentially promote long-term hippocampal recovery from seizures in adulthood. Hippocampus 2011, 21:584-608.
    • (2011) Hippocampus , vol.21 , pp. 584-608
    • Wong-Goodrich, S.J.E.1
  • 51
    • 69549121616 scopus 로고    scopus 로고
    • Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats
    • Thomas J.D., et al. Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. Neurotoxicol. Teratol. 2009, 31:303-311.
    • (2009) Neurotoxicol. Teratol. , vol.31 , pp. 303-311
    • Thomas, J.D.1
  • 52
    • 79952198463 scopus 로고    scopus 로고
    • Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats
    • Thomas J.D., et al. Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. Birth Defects Res. A: Clin. Mol. Teratol. 2010, 88:827-837.
    • (2010) Birth Defects Res. A: Clin. Mol. Teratol. , vol.88 , pp. 827-837
    • Thomas, J.D.1
  • 53
    • 0242661101 scopus 로고    scopus 로고
    • Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus
    • Craciunescu C.N., et al. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J. Nutr. 2003, 133:3614-3618.
    • (2003) J. Nutr. , vol.133 , pp. 3614-3618
    • Craciunescu, C.N.1
  • 54
    • 77955248113 scopus 로고    scopus 로고
    • Developmental aspects of the cholinergic system
    • Abreu-Villaça Y., et al. Developmental aspects of the cholinergic system. Behav. Brain Res. 2011, 221:367-378.
    • (2011) Behav. Brain Res. , vol.221 , pp. 367-378
    • Abreu-Villaça, Y.1
  • 55
    • 0031951352 scopus 로고    scopus 로고
    • Prenatal availability of choline modifies development of the hippocampal cholinergic system
    • Cermak J.M., et al. Prenatal availability of choline modifies development of the hippocampal cholinergic system. FASEB J. 1998, 12:349-357.
    • (1998) FASEB J. , vol.12 , pp. 349-357
    • Cermak, J.M.1
  • 56
    • 0033548534 scopus 로고    scopus 로고
    • Choline availability alters embryonic development of the hippocampus and septum in the rat
    • Albright C.D., et al. Choline availability alters embryonic development of the hippocampus and septum in the rat. Dev. Brain Res. 1999, 113:13-20.
    • (1999) Dev. Brain Res. , vol.113 , pp. 13-20
    • Albright, C.D.1
  • 57
    • 1542406042 scopus 로고    scopus 로고
    • Dietary prenatal choline supplementation alters postnatal hippocampal structure and function
    • Li Q., et al. Dietary prenatal choline supplementation alters postnatal hippocampal structure and function. J. Neurophysiol. 2004, 91:1545-1555.
    • (2004) J. Neurophysiol. , vol.91 , pp. 1545-1555
    • Li, Q.1
  • 58
    • 34247196759 scopus 로고    scopus 로고
    • Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats
    • Glenn M.J., et al. Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats. Eur. J. Neurosci. 2007, 25:2473-2482.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 2473-2482
    • Glenn, M.J.1
  • 59
    • 0033407121 scopus 로고    scopus 로고
    • Choline availability to the developing rat fetus alters adult hippocampal long-term potentiation
    • Jones J.P., et al. Choline availability to the developing rat fetus alters adult hippocampal long-term potentiation. Dev. Brain Res. 1999, 118:159-167.
    • (1999) Dev. Brain Res. , vol.118 , pp. 159-167
    • Jones, J.P.1
  • 60
    • 84882383499 scopus 로고    scopus 로고
    • Neuroprotective actions of perinatal choline nutrition
    • Blusztajn J.K., Mellott T.J. Neuroprotective actions of perinatal choline nutrition. Clin. Chem. Lab. Med. 2013, 51:591-599.
    • (2013) Clin. Chem. Lab. Med. , vol.51 , pp. 591-599
    • Blusztajn, J.K.1    Mellott, T.J.2
  • 61
    • 84875819547 scopus 로고    scopus 로고
    • Choline intake influences phosphatidylcholine DHA enrichment in nonpregnant women but not in pregnant women in the third trimester
    • West A.A., et al. Choline intake influences phosphatidylcholine DHA enrichment in nonpregnant women but not in pregnant women in the third trimester. Am. J. Clin. Nutr. 2013, 97:718-727.
    • (2013) Am. J. Clin. Nutr. , vol.97 , pp. 718-727
    • West, A.A.1
  • 62
    • 0033569752 scopus 로고    scopus 로고
    • Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway
    • DeLong C.J., et al. Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway. J. Biol. Chem. 1999, 274:29683-29688.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29683-29688
    • DeLong, C.J.1
  • 63
    • 78751502294 scopus 로고    scopus 로고
    • Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo
    • Pynn C.J., et al. Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo. J. Lipid Res. 2011, 52:399-407.
    • (2011) J. Lipid Res. , vol.52 , pp. 399-407
    • Pynn, C.J.1
  • 64
    • 51649100533 scopus 로고    scopus 로고
    • Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents
    • Wurtman R.J. Synapse formation and cognitive brain development: effect of docosahexaenoic acid and other dietary constituents. Metab. Clin. Exp. 2008, 57(Suppl. 2):S6-S10.
    • (2008) Metab. Clin. Exp. , vol.57 , Issue.SUPPL. 2
    • Wurtman, R.J.1
  • 65
    • 84865156836 scopus 로고    scopus 로고
    • Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants
    • Wu B.T.F., et al. Early second trimester maternal plasma choline and betaine are related to measures of early cognitive development in term infants. PLoS ONE 2012, 7:e43448.
    • (2012) PLoS ONE , vol.7
    • Wu, B.T.F.1
  • 66
    • 84878832681 scopus 로고    scopus 로고
    • Choline intake during pregnancy and child cognition at age 7 years
    • Boeke C.E., et al. Choline intake during pregnancy and child cognition at age 7 years. Am. J. Epidemiol. 2013, 177:1338-1347.
    • (2013) Am. J. Epidemiol. , vol.177 , pp. 1338-1347
    • Boeke, C.E.1
  • 67
    • 84869765864 scopus 로고    scopus 로고
    • Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial
    • Cheatham C.L., et al. Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. Am. J. Clin. Nutr. 2012, 96:1465-1472.
    • (2012) Am. J. Clin. Nutr. , vol.96 , pp. 1465-1472
    • Cheatham, C.L.1
  • 68
    • 42249100349 scopus 로고    scopus 로고
    • Choline concentrations in human maternal and cord blood and intelligence at 5y of age
    • Signore C., et al. Choline concentrations in human maternal and cord blood and intelligence at 5y of age. Am. J. Clin. Nutr. 2008, 87:896-902.
    • (2008) Am. J. Clin. Nutr. , vol.87 , pp. 896-902
    • Signore, C.1
  • 69
    • 84862247194 scopus 로고    scopus 로고
    • Maternal intake of methyl-donor nutrients and child cognition at 3 years of age
    • Villamor E., et al. Maternal intake of methyl-donor nutrients and child cognition at 3 years of age. Paediatr. Perinat. Epidemiol. 2012, 26:328-335.
    • (2012) Paediatr. Perinat. Epidemiol. , vol.26 , pp. 328-335
    • Villamor, E.1
  • 70
    • 3242698799 scopus 로고    scopus 로고
    • Periconceptional dietary intake of choline and betaine and neural tube defects in offspring
    • Shaw G.M., et al. Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am. J. Epidemiol. 2004, 160:102-109.
    • (2004) Am. J. Epidemiol. , vol.160 , pp. 102-109
    • Shaw, G.M.1
  • 71
    • 73349121672 scopus 로고    scopus 로고
    • Choline and risk of neural tube defects in a folate-fortified population
    • Shaw G.M., et al. Choline and risk of neural tube defects in a folate-fortified population. Epidemiology 2009, 20:714-719.
    • (2009) Epidemiology , vol.20 , pp. 714-719
    • Shaw, G.M.1
  • 72
    • 84877331048 scopus 로고    scopus 로고
    • Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk
    • Ross R.G., et al. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. Am. J. Psychiatry 2013, 170:290-298.
    • (2013) Am. J. Psychiatry , vol.170 , pp. 290-298
    • Ross, R.G.1
  • 73
    • 0036897309 scopus 로고    scopus 로고
    • Association of promoter variants in the alpha 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia
    • Leonard S., et al. Association of promoter variants in the alpha 7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Arch. Gen. Psychiatry 2002, 59:1085-1096.
    • (2002) Arch. Gen. Psychiatry , vol.59 , pp. 1085-1096
    • Leonard, S.1
  • 74
    • 77953779691 scopus 로고    scopus 로고
    • Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome
    • Moon J., et al. Perinatal choline supplementation improves cognitive functioning and emotion regulation in the Ts65Dn mouse model of Down syndrome. Behav. Neurosci. 2010, 124:346-361.
    • (2010) Behav. Neurosci. , vol.124 , pp. 346-361
    • Moon, J.1
  • 75
    • 84879376346 scopus 로고    scopus 로고
    • Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome
    • Velazquez R., et al. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neurobiol. Dis. 2013, 58:92-101.
    • (2013) Neurobiol. Dis. , vol.58 , pp. 92-101
    • Velazquez, R.1
  • 76
    • 84899485573 scopus 로고    scopus 로고
    • Perinatal choline supplementation improves spatial learning and increases cholinergic expression within basal forebrain cholinergic neurons (BFCNs) in the Ts65Dn mouse model of Down syndrome
    • Abstr. 152.06/W12
    • Ash J., et al. Perinatal choline supplementation improves spatial learning and increases cholinergic expression within basal forebrain cholinergic neurons (BFCNs) in the Ts65Dn mouse model of Down syndrome. Soc. Neurosci. 2011, Abstr. 152.06/W12.
    • (2011) Soc. Neurosci.
    • Ash, J.1
  • 77
    • 84860432472 scopus 로고    scopus 로고
    • Maternal high-methyl diet suppresses mammary carcinogenesis in female rat offspring
    • Cho K., et al. Maternal high-methyl diet suppresses mammary carcinogenesis in female rat offspring. Carcinogenesis 2012, 33:1106-1112.
    • (2012) Carcinogenesis , vol.33 , pp. 1106-1112
    • Cho, K.1
  • 78
    • 0642303160 scopus 로고    scopus 로고
    • Maternal and fetal hypothalamic-pituitary-adrenal axes during pregnancy and postpartum
    • Mastorakos G., Ilias I. Maternal and fetal hypothalamic-pituitary-adrenal axes during pregnancy and postpartum. Ann. N. Y. Acad. Sci. 2003, 997:136-149.
    • (2003) Ann. N. Y. Acad. Sci. , vol.997 , pp. 136-149
    • Mastorakos, G.1    Ilias, I.2
  • 79
    • 77956642106 scopus 로고    scopus 로고
    • Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology
    • Talens R.P., et al. Variation, patterns, and temporal stability of DNA methylation: considerations for epigenetic epidemiology. FASEB J. 2010, 24:3135-3144.
    • (2010) FASEB J. , vol.24 , pp. 3135-3144
    • Talens, R.P.1
  • 80
    • 15144344289 scopus 로고    scopus 로고
    • Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress
    • Liu D., et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science 1997, 277:1659-1662.
    • (1997) Science , vol.277 , pp. 1659-1662
    • Liu, D.1
  • 81
    • 0034489128 scopus 로고    scopus 로고
    • Impaired glucose tolerance and elevated blood pressure in low birth weight, nonobese, young South African adults: early programming of cortisol axis
    • Levitt N.S., et al. Impaired glucose tolerance and elevated blood pressure in low birth weight, nonobese, young South African adults: early programming of cortisol axis. J. Clin. Endocrinol. Metab. 2000, 85:4611-4618.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4611-4618
    • Levitt, N.S.1
  • 82
    • 67649227647 scopus 로고    scopus 로고
    • Preeclampsia: the role of angiogenic factors in its pathogenesis
    • Wang A., et al. Preeclampsia: the role of angiogenic factors in its pathogenesis. Physiology (Bethesda) 2009, 24:147-158.
    • (2009) Physiology (Bethesda) , vol.24 , pp. 147-158
    • Wang, A.1
  • 83
    • 10744227199 scopus 로고    scopus 로고
    • Circulating angiogenic factors and the risk of preeclampsia
    • Levine R.J., et al. Circulating angiogenic factors and the risk of preeclampsia. N. Engl. J. Med. 2004, 350:672-683.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 672-683
    • Levine, R.J.1
  • 84
    • 69949088317 scopus 로고    scopus 로고
    • The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation
    • Kim J.Y., et al. The expression of VEGF receptor genes is concurrently influenced by epigenetic gene silencing of the genes and VEGF activation. Epigenetics 2009, 4:313-321.
    • (2009) Epigenetics , vol.4 , pp. 313-321
    • Kim, J.Y.1
  • 85
    • 84899055534 scopus 로고    scopus 로고
    • Choline inadequacy impairs trophoblast function and vascularization in cultured human placental trophoblasts
    • Jiang X., et al. Choline inadequacy impairs trophoblast function and vascularization in cultured human placental trophoblasts. J. Cell. Physiol. 2013, 10.1002/jcp.24526.
    • (2013) J. Cell. Physiol.
    • Jiang, X.1
  • 86
    • 77955496122 scopus 로고    scopus 로고
    • Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma
    • Fischer L.M., et al. Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. Am. J. Clin. Nutr. 2010, 92:336-346.
    • (2010) Am. J. Clin. Nutr. , vol.92 , pp. 336-346
    • Fischer, L.M.1
  • 87
    • 79954519615 scopus 로고    scopus 로고
    • Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes
    • Schaible T.D., et al. Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes. Hum. Mol. Genet. 2011, 20:1687-1696.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 1687-1696
    • Schaible, T.D.1
  • 88
    • 55849150592 scopus 로고    scopus 로고
    • In utero supplementation with methyl donors enhances allergic airway disease in mice
    • Hollingsworth J.W., et al. In utero supplementation with methyl donors enhances allergic airway disease in mice. J. Clin. Invest. 2008, 118:3462-3469.
    • (2008) J. Clin. Invest. , vol.118 , pp. 3462-3469
    • Hollingsworth, J.W.1
  • 89
    • 84867562587 scopus 로고    scopus 로고
    • Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology
    • Entringer S., et al. Fetal programming of body composition, obesity, and metabolic function: the role of intrauterine stress and stress biology. J. Nutr. Metab. 2012, 2012:632548.
    • (2012) J. Nutr. Metab. , vol.2012 , pp. 632548
    • Entringer, S.1
  • 90
    • 51849124035 scopus 로고    scopus 로고
    • Methyl donor supplementation prevents transgenerational amplification of obesity
    • Waterland R.A., et al. Methyl donor supplementation prevents transgenerational amplification of obesity. Int. J. Obes. (Lond.) 2008, 32:1373-1379.
    • (2008) Int. J. Obes. (Lond.) , vol.32 , pp. 1373-1379
    • Waterland, R.A.1
  • 92
    • 84865591162 scopus 로고    scopus 로고
    • The penetrance of an epigenetic trait in mice is progressively yet reversibly increased by selection and environment
    • Cropley J.E., et al. The penetrance of an epigenetic trait in mice is progressively yet reversibly increased by selection and environment. Proc. Biol. Sci. 2012, 279:2347-2353.
    • (2012) Proc. Biol. Sci. , vol.279 , pp. 2347-2353
    • Cropley, J.E.1
  • 93
    • 14844307097 scopus 로고    scopus 로고
    • Epigenetic regulation by histone methylation and histone variants
    • Cheung P., Lau P. Epigenetic regulation by histone methylation and histone variants. Mol. Endocrinol. 2005, 19:563-573.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 563-573
    • Cheung, P.1    Lau, P.2
  • 94
    • 11244251792 scopus 로고    scopus 로고
    • Human placenta secretes apolipoprotein B-100-containing lipoproteins
    • Madsen E.M., et al. Human placenta secretes apolipoprotein B-100-containing lipoproteins. J. Biol. Chem. 2004, 279:55271-55276.
    • (2004) J. Biol. Chem. , vol.279 , pp. 55271-55276
    • Madsen, E.M.1
  • 95
    • 33746504112 scopus 로고    scopus 로고
    • Common genetic polymorphisms affect the human requirement for the nutrient choline
    • Da Costa K-A., et al. Common genetic polymorphisms affect the human requirement for the nutrient choline. FASEB J. 2006, 20:1336-1344.
    • (2006) FASEB J. , vol.20 , pp. 1336-1344
    • Da Costa, K.-A.1
  • 96
    • 27644581598 scopus 로고    scopus 로고
    • Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans
    • Kohlmeier M., et al. Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:16025-16030.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 16025-16030
    • Kohlmeier, M.1
  • 97
    • 51749099188 scopus 로고    scopus 로고
    • Adequate intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load
    • Veenema K., et al. Adequate intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load. Am. J. Clin. Nutr. 2008, 88:685-692.
    • (2008) Am. J. Clin. Nutr. , vol.88 , pp. 685-692
    • Veenema, K.1
  • 98
    • 57049125142 scopus 로고    scopus 로고
    • Choline status is not a reliable indicator of moderate changes in dietary choline consumption in premenopausal women
    • Abratte C.M., et al. Choline status is not a reliable indicator of moderate changes in dietary choline consumption in premenopausal women. J. Nutr. Biochem. 2009, 20:62-69.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 62-69
    • Abratte, C.M.1
  • 99
    • 79251524576 scopus 로고    scopus 로고
    • MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline
    • Yan J., et al. MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am. J. Clin. Nutr. 2011, 93:348-355.
    • (2011) Am. J. Clin. Nutr. , vol.93 , pp. 348-355
    • Yan, J.1
  • 100
    • 80054691714 scopus 로고    scopus 로고
    • Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas
    • Teng Y-W., et al. Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J. Biol. Chem. 2011, 286:36258-36267.
    • (2011) J. Biol. Chem. , vol.286 , pp. 36258-36267
    • Teng, Y.-W.1
  • 101
    • 77955781541 scopus 로고    scopus 로고
    • Deletion of murine choline dehydrogenase results in diminished sperm motility
    • Johnson A.R., et al. Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J. 2010, 24:2752-2761.
    • (2010) FASEB J. , vol.24 , pp. 2752-2761
    • Johnson, A.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.