Choline intake during pregnancy and child cognition at age 7 years

American Journal of Epidemiology

Volumn 177, Issue 12, 2013, Pages 1338-1347

  Boeke, Caroline E ^a,b   Gillman, Matthew W ^c   Hughes, Michael D ^a   Rifas Shiman, Sheryl L ^c   Villamor, Eduardo ^a,d   Oken, Emily ^c  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD PILGRIM HEALTH CARE INSTITUTE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

choline; cognition; folate; memory; pregnancy

Indexed keywords

BETAINE; CHOLINE; FOLIC ACID;

BIOLOGICAL UPTAKE; CHILD HEALTH; COGNITION; LEARNING; MEMORY; MENTAL HEALTH; NUTRIENT; PREGNANCY; VITAMIN;

ADULT; ARTICLE; CHILD; COGNITION; FEMALE; FOOD INTAKE; GROUPS BY AGE; HUMAN; INTELLIGENCE; INTELLIGENCE TEST; KAUFMAN BRIEF INTELLIGENCE TEST; LEARNING; MALE; MATERNAL NUTRITION; MEMORY; NEUROPSYCHOLOGICAL TEST; PREGNANCY; SCHOOL CHILD; SECOND TRIMESTER PREGNANCY; UNITED STATES; VISUAL MEMORY; WIDE RANGE ASSESSMENT OF MEMORY AND LEARNING;

CHOLINE; COGNITION; FOLATE; MEMORY; PREGNANCY;

ADULT; BETAINE; CHILD; CHILD DEVELOPMENT; CHOLINE; COGNITION; DIETARY SUPPLEMENTS; FEMALE; FOLIC ACID; HUMANS; INTELLIGENCE; MALE; MASSACHUSETTS; MEMORY; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PRENATAL EXPOSURE DELAYED EFFECTS; SMOKING; SOCIOECONOMIC FACTORS; VITAMIN B 12;

MASSACHUSETTS; UNITED STATES;

ANIMALIA;

EID: 84878832681     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kws395     Document Type: Article

References (41)

1. Zeisel SH. Importance of methyl donors during reproduction. Am J Clin Nutr. 2009;89(2):673S-677S.
2. Sarter M, Parikh V. Choline transporters, cholinergic transmission and cognition. Nat Rev Neurosci. 2005;6(1): 48-56.
3. McCann JC, Hudes M, Ames BN. An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring. Neurosci Biobehav Rev. 2006;30(5):696-712.
4. Meck WH, Williams CL. Choline supplementation during prenatal development reduces proactive interference in spatial memory. Brain Res Dev Brain Res. 1999;118(1-2):51-59.
5. Meck WH, Williams CL. Metabolic imprinting of choline by its availability during gestation: implications for memory and attentional processing across the lifespan. Neurosci Biobehav Rev. 2003;27(4):385-399.
6. Mellott TJ, Williams CL, Meck WH, et al. Prenatal choline supplementation advances hippocampal development and enhances MAPK and CREB activation. FASEB J. 2004; 18(3):545-547.
7. Niculescu MD, Craciunescu CN, Zeisel SH. Dietary choline deficiency alters global and gene-specific DNA methylation in the developing hippocampus of mouse fetal brains. FASEB J. 2006;20(1):43-49.
8. Albright CD, Tsai AY, Friedrich CB, et al. Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain Res Dev Brain Res.
9. Albright CD, Friedrich CB, Brown EC, et al. Maternal dietary choline availability alters mitosis, apoptosis and the localization of TOAD-64 protein in the developing fetal rat septum. Brain Res Dev Brain Res. 1999;115(2):123-129.
10. Signore C, Ueland PM, Troendle J, et al. Choline concentrations in human maternal and cord blood and intelligence at 5 y of age. Am J Clin Nutr. 2008;87(4): 896-902.
11. Villamor E, Rifas-Shiman SL, Gillman MW, et al. Maternal intake of methyl-donor nutrients and child cognition at 3 years of age. Paediatr Perinat Epidemiol. 2012;26(4): 328-335.
12. Poly C, Massaro JM, Seshadri S, et al. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr. 2011;94(6):1584-1591.
13. Bhate V, Deshpande S, Bhat D, et al. Vitamin B12 status of pregnant Indian women and cognitive function in their 9-year-old children. Food Nutr Bull. 2008;29(4): 249-254.
14. Veena SR, Krishnaveni GV, Srinivasan K, et al. Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9-to 10-year-old children in South India. J Nutr.
15. del Rio Garcia C, Torres-Sanchez L, Chen J, et al. Maternal MTHFR 677C>T genotype and dietary intake of folate and vitamin B(12): their impact on child neurodevelopment. Nutr Neurosci. 2009;12(1):13-20.
16. Gillman MW, Rich-Edwards JW, Rifas-Shiman SL, et al. Maternal age and other predictors of newborn blood pressure. J Pediatr. 2004;144(2):240-245.
17. Rimm EB, Giovannucci EL, Stampfer MJ, et al. Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. Am J Epidemiol. 1992;135(10): 1114-1126.
18. Willett WC, Sampson L, Stampfer MJ, et al. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol. 1985;122(1):51-65.
19. Fawzi WW, Rifas-Shiman SL, Rich-Edwards JW, et al. Calibration of a semi-quantitative food frequency questionnaire in early pregnancy. Ann Epidemiol. 2004; 14(10):754-762.
20. Cho E, Zeisel SH, Jacques P, et al. Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr. 2006;83(4): 905-911.
21. Verkleij-Hagoort AC, de Vries JH, Stegers MP, et al. Validation of the assessment of folate and vitamin B12 intake in women of reproductive age: the method of triads. Eur J Clin Nutr. 2007;61(5):610-615.
22. Willett WC. Nutritional Epidemiology. New York, NY: Oxford University Press; 1998.
23. Adams W, Sheslow D. WRAML2: Wide Range Assessment of Memory and Learning, Second Edition. Wilmington, DE: Wide Range, Inc; 2003.
24. Kaufman AS, Kaufman NL. Kaufman Brief Intelligence Test, Second Edition. Minneapolis, MN: American Guidance Service, Inc; 2004.
25. Oken E, Radesky JS, Wright RO, et al. Maternal fish intake during pregnancy, blood mercury levels, and child cognition at age 3 years in a US cohort. Am J Epidemiol. 2008; 167(10):1171-1181.
26. Donahue SM, Rifas-Shiman SL, Olsen SF, et al. Associations of maternal prenatal dietary intake of n-3 and n-6 fatty acids with maternal and umbilical cord blood levels. Prostaglandins Leukot Essent Fatty Acids. 2009;80(5-6): 289-296.
27. Coleman PK, Reardon DC, Cougle J. The quality of the caregiving environment and child developmental outcomes associated with maternal history of abortion using the NLSY data. J Child Psychol Psychiatry. 2002;43(6):743-757.
28. Albright CD, Siwek DF, Craciunescu CN, et al. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci. 2003;6(2):129-134.
29. Craciunescu CN, Albright CD, Mar MH, et al. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr.
30. Niculescu MD, Craciunescu CN, Zeisel SH. Gene expression profiling of choline-deprived neural precursor cells isolated from mouse brain. Brain Res Mol Brain Res. 2005;134(2): 309-322.
31. Yen CL, Mar MH, Meeker RB, et al. Choline deficiency induces apoptosis in primary cultures of fetal neurons. FASEB J. 2001;15(10):1704-1710.
32. Niculescu MD, Yamamuro Y, Zeisel SH. Choline availability modulates human neuroblastoma cell proliferation and alters the methylation of the promoter region of the cyclindependent kinase inhibitor 3 gene. J Neurochem. 2004;89(5): 1252-1259.
33. Yasik AE, Saigh PA, Oberfield RA, et al. Posttraumatic stress disorder: memory and learning performance in children and adolescents. Biol Psychiatry. 2007;61(3):382-388.
34. Andersson U. Working memory as a predictor of written arithmetical skills in children: the importance of central executive functions. Br J Educ Psychol. 2008;78(2): 181-203.
35. Gathercole SE, Brown L, Pickering SJ. Working memory assessments at school entry as longitudinal 109 predictors of National Curriculum attainment levels. Educ Child Psychol.
36. Henry L, MacLean M. Relationships between working memory, expressive vocabulary and arithmetical reasoning in children with and without intellectual disabilities. Educ Child Psychol. 2003;20(3):51-64.
37. Semba K, Fibiger HC. Time of origin of cholinergic neurons in the rat basal forebrain. J Comp Neurol. 1988;269(1):87-95.
38. Fischer LM, daCosta KA, Kwock L, et al. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007;85(5):1275-1285.
39. Food and Nutrition Board Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline. Washington, DC: National Academy Press 1998.
40. Williams CL, Meck WH, Heyer DD, et al. Hypertrophy of basal forebrain neurons and enhanced visuospatial memory in perinatally choline-supplemented rats. Brain Res. 1998; 794(2):225-238.
41. Julvez J, Fortuny J, Mendez M, et al. Maternal use of folic acid supplements during pregnancy and four-yearold neurodevelopment in a population-based birth cohort. Paediatr Perinat Epidemiol. 2009;23(3): 199-206.