Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans

FASEB Journal

Volumn 26, Issue 8, 2012, Pages 3563-3574

  Jiang, Xinyin ^a   Yan, Jian ^a   West, Allyson A ^a   Perry, Cydne A ^a   Malysheva, Olga V ^a   Devapatla, Srisatish ^a   Pressman, Eva ^b   Vermeylen, Francoise ^c   Caudill, Marie A ^a  

^a Department of Obstetrics Gynecology   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^c Cayuga Medical Center   (United States)

Author keywords

DNA methylation; HPA axis; Methyl donor; Prenatal nutrition

Indexed keywords

CHOLINE; CORTICOTROPIN RELEASING FACTOR; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; GLUCOCORTICOID RECEPTOR; HISTONE H3; HISTONE METHYLTRANSFERASE; HYDROCORTISONE; LYSINE; METHYLTRANSFERASE;

ADULT; ARTICLE; CONTROLLED STUDY; CPG ISLAND; CRH GENE; DNA METHYLATION; EPIGENETICS; FEMALE; FETUS; GENE; GENE EXPRESSION; GNAS AS1 GENE; HORMONAL REGULATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE RELEASE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IGF2 GENE; IL10 GENE; LEP GENE; LEUKOCYTE; MATERNAL NUTRITION; NEWBORN; NORMAL HUMAN; NR3C1 GENE; PERINATAL PERIOD; PLACENTA; PREGNANT WOMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; THIRD TRIMESTER PREGNANCY; UMBILICAL CORD BLOOD; VENOUS BLOOD;

ADULT; CHOLINE; CORTICOTROPIN-RELEASING HORMONE; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; FETAL BLOOD; HUMANS; HYDROCORTISONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PITUITARY-ADRENAL SYSTEM; PLACENTA; PREGNANCY; PREGNANCY TRIMESTER, THIRD; RECEPTORS, GLUCOCORTICOID;

EID: 84864772359     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-207894     Document Type: Article

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