메뉴 건너뛰기




Volumn 8, Issue 3, 2014, Pages 704-716

CPSF4 activates telomerase reverse transcriptase and predicts poor prognosis in human lung adenocarcinomas

Author keywords

CPSF4; HTERT; Lung cancer; Promoter; Telomerase

Indexed keywords

CALCIUM ION; CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR 4; MESSENGER RNA; PROTEIN; SMALL INTERFERING RNA; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; TELOMERASE; TERT PROTEIN, HUMAN;

EID: 84899476575     PISSN: 15747891     EISSN: 18780261     Source Type: Journal    
DOI: 10.1016/j.molonc.2014.02.001     Document Type: Article
Times cited : (29)

References (49)
  • 2
    • 1842329727 scopus 로고    scopus 로고
    • The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins
    • Barabino S.M., Hubner W., Jenny A., Minvielle-Sebastia L., Keller W. The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins. Genes Dev. 1997, 11:1703-1716.
    • (1997) Genes Dev. , vol.11 , pp. 1703-1716
    • Barabino, S.M.1    Hubner, W.2    Jenny, A.3    Minvielle-Sebastia, L.4    Keller, W.5
  • 4
    • 33749631593 scopus 로고    scopus 로고
    • Telomeres: prognostic markers for solid tumors
    • Journal International du Cancer
    • Bisoffi M., Heaphy C.M., Griffith J.K. Telomeres: prognostic markers for solid tumors. Int. J. Cancer 2006, 119:2255-2260. Journal International du Cancer.
    • (2006) Int. J. Cancer , vol.119 , pp. 2255-2260
    • Bisoffi, M.1    Heaphy, C.M.2    Griffith, J.K.3
  • 5
    • 25444522262 scopus 로고    scopus 로고
    • Telomerase and Cancer: Kirk A. Landon-AACR prize for basic cancer research lecture
    • Blackburn E.H. Telomerase and Cancer: Kirk A. Landon-AACR prize for basic cancer research lecture. Mol. cancer Res. : MCR 2005, 3:477-482.
    • (2005) Mol. cancer Res. : MCR , vol.3 , pp. 477-482
    • Blackburn, E.H.1
  • 6
    • 33749534161 scopus 로고    scopus 로고
    • Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
    • Blackburn E.H., Greider C.W., Szostak J.W. Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging. Nat. Med. 2006, 12:1133-1138.
    • (2006) Nat. Med. , vol.12 , pp. 1133-1138
    • Blackburn, E.H.1    Greider, C.W.2    Szostak, J.W.3
  • 7
    • 0033152429 scopus 로고    scopus 로고
    • Telomerase and the maintenance of chromosome ends
    • Bryan T.M., Cech T.R. Telomerase and the maintenance of chromosome ends. Curr. Opin. Cell Biol. 1999, 11:318-324.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 318-324
    • Bryan, T.M.1    Cech, T.R.2
  • 8
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat. Med. 1997, 3:1271-1274.
    • (1997) Nat. Med. , vol.3 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 9
    • 0037948220 scopus 로고    scopus 로고
    • Strange bedfellows: polyadenylation factors at the promoter
    • Calvo O., Manley J.L. Strange bedfellows: polyadenylation factors at the promoter. Genes Dev. 2003, 17:1321-1327.
    • (2003) Genes Dev. , vol.17 , pp. 1321-1327
    • Calvo, O.1    Manley, J.L.2
  • 10
    • 58149335437 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis
    • Cheng Y.W., Wu T.C., Chen C.Y., Chou M.C., Ko J.L., Lee H. Human telomerase reverse transcriptase activated by E6 oncoprotein is required for human papillomavirus-16/18-infected lung tumorigenesis. Clin. cancer Res. : An Official J. Am. Assoc. Cancer Res. 2008, 14:7173-7179.
    • (2008) Clin. cancer Res. : An Official J. Am. Assoc. Cancer Res. , vol.14 , pp. 7173-7179
    • Cheng, Y.W.1    Wu, T.C.2    Chen, C.Y.3    Chou, M.C.4    Ko, J.L.5    Lee, H.6
  • 11
    • 0031047426 scopus 로고    scopus 로고
    • Replicative senescence and cell immortality: the role of telomeres and telomerase
    • Chiu C.P., Harley C.B. Replicative senescence and cell immortality: the role of telomeres and telomerase. Proc. Soc. Exp. Biol. Med. 1997, 214:99-106.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.214 , pp. 99-106
    • Chiu, C.P.1    Harley, C.B.2
  • 12
    • 34147095342 scopus 로고    scopus 로고
    • Protein composition of catalytically active human telomerase from immortal cells
    • Cohen S.B., Graham M.E., Lovrecz G.O., Bache N., Robinson P.J., Reddel R.R. Protein composition of catalytically active human telomerase from immortal cells. Science 2007, 315:1850-1853.
    • (2007) Science , vol.315 , pp. 1850-1853
    • Cohen, S.B.1    Graham, M.E.2    Lovrecz, G.O.3    Bache, N.4    Robinson, P.J.5    Reddel, R.R.6
  • 13
    • 0033062578 scopus 로고    scopus 로고
    • Telomere maintenance mechanisms and cellular immortalization
    • Colgin L.M., Reddel R.R. Telomere maintenance mechanisms and cellular immortalization. Curr. Opin. Gen. Dev. 1999, 9:97-103.
    • (1999) Curr. Opin. Gen. Dev. , vol.9 , pp. 97-103
    • Colgin, L.M.1    Reddel, R.R.2
  • 14
    • 0346249716 scopus 로고    scopus 로고
    • The FIP1L1-PDGFRalpha kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia
    • Cools J., Stover E.H., Wlodarska I., Marynen P., Gilliland D.G. The FIP1L1-PDGFRalpha kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia. Curr. Opin. Hematol. 2004, 11:51-57.
    • (2004) Curr. Opin. Hematol. , vol.11 , pp. 51-57
    • Cools, J.1    Stover, E.H.2    Wlodarska, I.3    Marynen, P.4    Gilliland, D.G.5
  • 15
    • 84858750992 scopus 로고    scopus 로고
    • Regulation of the human catalytic subunit of telomerase (hTERT)
    • Daniel M., Peek G.W., Tollefsbol T.O. Regulation of the human catalytic subunit of telomerase (hTERT). Gene 2012, 498:135-146.
    • (2012) Gene , vol.498 , pp. 135-146
    • Daniel, M.1    Peek, G.W.2    Tollefsbol, T.O.3
  • 16
    • 0034331199 scopus 로고    scopus 로고
    • Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors
    • de Vries H., Ruegsegger U., Hubner W., Friedlein A., Langen H., Keller W. Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. EMBO J. 2000, 19:5895-5904.
    • (2000) EMBO J. , vol.19 , pp. 5895-5904
    • de Vries, H.1    Ruegsegger, U.2    Hubner, W.3    Friedlein, A.4    Langen, H.5    Keller, W.6
  • 17
    • 34548853126 scopus 로고    scopus 로고
    • Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells
    • Deng W.G., Jayachandran G., Wu G., Xu K., Roth J.A., Ji L. Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells. J.Biol. Chem. 2007, 282:26460-26470.
    • (2007) J.Biol. Chem. , vol.282 , pp. 26460-26470
    • Deng, W.G.1    Jayachandran, G.2    Wu, G.3    Xu, K.4    Roth, J.A.5    Ji, L.6
  • 18
    • 33745932460 scopus 로고    scopus 로고
    • Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
    • Deng W.G., Tang S.T., Tseng H.P., Wu K.K. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood 2006, 108:518-524.
    • (2006) Blood , vol.108 , pp. 518-524
    • Deng, W.G.1    Tang, S.T.2    Tseng, H.P.3    Wu, K.K.4
  • 19
    • 0346996870 scopus 로고    scopus 로고
    • Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation
    • Deng W.G., Wu K.K. Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation. J.Immunol. 2003, 171:6581-6588.
    • (2003) J.Immunol. , vol.171 , pp. 6581-6588
    • Deng, W.G.1    Wu, K.K.2
  • 20
    • 1542343955 scopus 로고    scopus 로고
    • Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators
    • Deng W.G., Zhu Y., Wu K.K. Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators. Blood 2004, 103:2135-2142.
    • (2004) Blood , vol.103 , pp. 2135-2142
    • Deng, W.G.1    Zhu, Y.2    Wu, K.K.3
  • 21
    • 0037148401 scopus 로고    scopus 로고
    • Regulation of the human telomerase reverse transcriptase gene
    • Ducrest A.L., Szutorisz H., Lingner J., Nabholz M. Regulation of the human telomerase reverse transcriptase gene. Oncogene 2002, 21:541-552.
    • (2002) Oncogene , vol.21 , pp. 541-552
    • Ducrest, A.L.1    Szutorisz, H.2    Lingner, J.3    Nabholz, M.4
  • 24
    • 1842474941 scopus 로고    scopus 로고
    • The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management
    • Gotlib J., Cools J., Malone J.M., Schrier S.L., Gilliland D.G., Coutre S.E. The FIP1L1-PDGFRalpha fusion tyrosine kinase in hypereosinophilic syndrome and chronic eosinophilic leukemia: implications for diagnosis, classification, and management. Blood 2004, 103:2879-2891.
    • (2004) Blood , vol.103 , pp. 2879-2891
    • Gotlib, J.1    Cools, J.2    Malone, J.M.3    Schrier, S.L.4    Gilliland, D.G.5    Coutre, S.E.6
  • 25
    • 39749163359 scopus 로고    scopus 로고
    • Telomerase and cancer therapeutics
    • Harley C.B. Telomerase and cancer therapeutics. Nat. Rev. Cancer 2008, 8:167-179.
    • (2008) Nat. Rev. Cancer , vol.8 , pp. 167-179
    • Harley, C.B.1
  • 27
    • 1442313922 scopus 로고    scopus 로고
    • Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase
    • Kaufmann I., Martin G., Friedlein A., Langen H., Keller W. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. EMBO J. 2004, 23:616-626.
    • (2004) EMBO J. , vol.23 , pp. 616-626
    • Kaufmann, I.1    Martin, G.2    Friedlein, A.3    Langen, H.4    Keller, W.5
  • 28
    • 67449103686 scopus 로고    scopus 로고
    • Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation
    • Kiefer H., Mizutani A., Iemura S., Natsume T., Ando H., Kuroda Y., Mikoshiba K. Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation. J.Biol. Chem. 2009, 284:10694-10705.
    • (2009) J.Biol. Chem. , vol.284 , pp. 10694-10705
    • Kiefer, H.1    Mizutani, A.2    Iemura, S.3    Natsume, T.4    Ando, H.5    Kuroda, Y.6    Mikoshiba, K.7
  • 30
    • 0035831030 scopus 로고    scopus 로고
    • The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression
    • Kleiman F.E., Manley J.L. The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression. Cell 2001, 104:743-753.
    • (2001) Cell , vol.104 , pp. 743-753
    • Kleiman, F.E.1    Manley, J.L.2
  • 31
    • 49749139661 scopus 로고    scopus 로고
    • Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
    • Kyo S., Takakura M., Fujiwara T., Inoue M. Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci. 2008, 99:1528-1538.
    • (2008) Cancer Sci. , vol.99 , pp. 1528-1538
    • Kyo, S.1    Takakura, M.2    Fujiwara, T.3    Inoue, M.4
  • 33
    • 0032765047 scopus 로고    scopus 로고
    • Studies of the molecular mechanisms in the regulation of telomerase activity
    • Liu J.P. Studies of the molecular mechanisms in the regulation of telomerase activity. FASEB J. Official Pub. Fed. Am. Soc. Exp. Biol. 1999, 13:2091-2104.
    • (1999) FASEB J. Official Pub. Fed. Am. Soc. Exp. Biol. , vol.13 , pp. 2091-2104
    • Liu, J.P.1
  • 38
    • 0032086357 scopus 로고    scopus 로고
    • Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs
    • Nemeroff M.E., Barabino S.M., Li Y., Keller W., Krug R.M. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs. Mol. Cell 1998, 1:991-1000.
    • (1998) Mol. Cell , vol.1 , pp. 991-1000
    • Nemeroff, M.E.1    Barabino, S.M.2    Li, Y.3    Keller, W.4    Krug, R.M.5
  • 40
    • 84876976986 scopus 로고    scopus 로고
    • Novel anticancer therapeutics targeting telomerase
    • Ruden M., Puri N. Novel anticancer therapeutics targeting telomerase. Cancer Treat. Rev. 2013, 39:444-456.
    • (2013) Cancer Treat. Rev. , vol.39 , pp. 444-456
    • Ruden, M.1    Puri, N.2
  • 41
    • 0033575958 scopus 로고    scopus 로고
    • Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments
    • Saretzki G., Sitte N., Merkel U., Wurm R.E., von Zglinicki T. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments. Oncogene 1999, 18:5148-5158.
    • (1999) Oncogene , vol.18 , pp. 5148-5158
    • Saretzki, G.1    Sitte, N.2    Merkel, U.3    Wurm, R.E.4    von Zglinicki, T.5
  • 42
    • 39449092745 scopus 로고    scopus 로고
    • Targeting telomerase for cancer therapeutics
    • Shay J.W., Keith W.N. Targeting telomerase for cancer therapeutics. Br. J. Cancer 2008, 98:677-683.
    • (2008) Br. J. Cancer , vol.98 , pp. 677-683
    • Shay, J.W.1    Keith, W.N.2
  • 43
    • 0033082526 scopus 로고    scopus 로고
    • Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells
    • Takakura M., Kyo S., Kanaya T., Hirano H., Takeda J., Yutsudo M., Inoue M. Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells. Cancer Res. 1999, 59:551-557.
    • (1999) Cancer Res. , vol.59 , pp. 551-557
    • Takakura, M.1    Kyo, S.2    Kanaya, T.3    Hirano, H.4    Takeda, J.5    Yutsudo, M.6    Inoue, M.7
  • 44
    • 77949310670 scopus 로고    scopus 로고
    • Telomere and telomerase as targets for cancer therapy
    • Tian X., Chen B., Liu X. Telomere and telomerase as targets for cancer therapy. Appl. Biochem. Biotechnol. 2010, 160:1460-1472.
    • (2010) Appl. Biochem. Biotechnol. , vol.160 , pp. 1460-1472
    • Tian, X.1    Chen, B.2    Liu, X.3
  • 45
    • 0035889901 scopus 로고    scopus 로고
    • Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features
    • Toomey D., Smyth G., Condron C., Kay E., Conroy R., Foley D., Hong C., Hogan B., Toner S., McCormick P., Broe P., Kelly C., Bouchier-Hayes D. Immune function, telomerase, and angiogenesis in patients with primary, operable nonsmall cell lung carcinoma: tumor size and lymph node status remain the most important prognostic features. Cancer 2001, 92:2648-2657.
    • (2001) Cancer , vol.92 , pp. 2648-2657
    • Toomey, D.1    Smyth, G.2    Condron, C.3    Kay, E.4    Conroy, R.5    Foley, D.6    Hong, C.7    Hogan, B.8    Toner, S.9    McCormick, P.10    Broe, P.11    Kelly, C.12    Bouchier-Hayes, D.13
  • 46
    • 0034935020 scopus 로고    scopus 로고
    • Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors
    • Topalian S.L., Kaneko S., Gonzales M.I., Bond G.L., Ward Y., Manley J.L. Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors. Mol. Cell. Biol. 2001, 21:5614-5623.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 5614-5623
    • Topalian, S.L.1    Kaneko, S.2    Gonzales, M.I.3    Bond, G.L.4    Ward, Y.5    Manley, J.L.6
  • 49
    • 33646851581 scopus 로고    scopus 로고
    • Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
    • Zhu C.Q., Cutz J.C., Liu N., Lau D., Shepherd F.A., Squire J.A., Tsao M.S. Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. Br. J. Cancer 2006, 94:1452-1459.
    • (2006) Br. J. Cancer , vol.94 , pp. 1452-1459
    • Zhu, C.Q.1    Cutz, J.C.2    Liu, N.3    Lau, D.4    Shepherd, F.A.5    Squire, J.A.6    Tsao, M.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.