-
3
-
-
0032923377
-
The secretory route of the leaderless protein interleukin 1β involves exocytosis of endolysosome-related vesicles
-
Andrei C, Dazzi C, Lotti L, Torrisi MR, Chumini G, Rubartelli A. 1999. The secretory route of the leaderless protein interleukin 1β involves exocytosis of endolysosome-related vesicles. Mol Biol Cell 10:1463-1475.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1463-1475
-
-
Andrei, C.1
Dazzi, C.2
Lotti, L.3
Torrisi, M.R.4
Chumini, G.5
Rubartelli, A.6
-
5
-
-
8344233332
-
Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia
-
Benchoua A, Braudeau J, Reis A, Couriaud C, Onténiente B. 2004. Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia. J Cereb Blood Flow Metab 24:1272-1279.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 1272-1279
-
-
Benchoua, A.1
Braudeau, J.2
Reis, A.3
Couriaud, C.4
Onténiente, B.5
-
6
-
-
0025261122
-
IL-1β is secreted by activated murine macrophages as biologically inactive precursor
-
Beuscher HU, Gunther C, Rollinghoff M. 1990. IL-1β is secreted by activated murine macrophages as biologically inactive precursor. J Immunol 144:2179-2183.
-
(1990)
J Immunol
, vol.144
, pp. 2179-2183
-
-
Beuscher, H.U.1
Gunther, C.2
Rollinghoff, M.3
-
7
-
-
34047179487
-
Caspase-1-dependent processing of prointerleukin-1β is cytosolic and precedes cell death
-
Brough D, Rothwell NJ. 2007. Caspase-1-dependent processing of prointerleukin-1β is cytosolic and precedes cell death. J Cell Sci 120:772-781.
-
(2007)
J Cell Sci
, vol.120
, pp. 772-781
-
-
Brough, D.1
Rothwell, N.J.2
-
8
-
-
0026561259
-
Goblet cell hyperplasia in large intrapulmonary airways after intratracheal injection of cathepsin B into hamsters
-
Cardozo C, Padilla ML, Choi HS, Lesser M. 1992. Goblet cell hyperplasia in large intrapulmonary airways after intratracheal injection of cathepsin B into hamsters. Am Rev Respir Dis 145:675-679.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 675-679
-
-
Cardozo, C.1
Padilla, M.L.2
Choi, H.S.3
Lesser, M.4
-
9
-
-
0036286317
-
Rat microglial cells secrete predominantly the precursor of interleulin-1β in response to lipopolysaccharide
-
Chauvet N, Palin K, Verrier D, Poole S, Dantzer R, Lestage J. 2001. Rat microglial cells secrete predominantly the precursor of interleulin-1β in response to lipopolysaccharide. Eur J Neurosci 14:609-617.
-
(2001)
Eur J Neurosci
, vol.14
, pp. 609-617
-
-
Chauvet, N.1
Palin, K.2
Verrier, D.3
Poole, S.4
Dantzer, R.5
Lestage, J.6
-
10
-
-
0035918267
-
Mechanisms underlying neuronal death induced by chromogranin A-activated microglia
-
Ciesielski-Treska J, Ulrich G, Chasserot-Golaz S, Zwiller J, Revel MO, Aunis D, Bader MF. 2001. Mechanisms underlying neuronal death induced by chromogranin A-activated microglia. J Biol Chem 276:13113-13120.
-
(2001)
J Biol Chem
, vol.276
, pp. 13113-13120
-
-
Ciesielski-Treska, J.1
Ulrich, G.2
Chasserot-Golaz, S.3
Zwiller, J.4
Revel, M.O.5
Aunis, D.6
Bader, M.F.7
-
11
-
-
0032486395
-
Chromogranin A induces a neurotoxic phenotype in brain microglial cells
-
Ciesielski-Treska J, Ulrich G, Taupenot L, Chasserot-Golaz S, Corti A, Aunis D, Bader MF. 1998. Chromogranin A induces a neurotoxic phenotype in brain microglial cells. J Biol Chem 273:14339-14346.
-
(1998)
J Biol Chem
, vol.273
, pp. 14339-14346
-
-
Ciesielski-Treska, J.1
Ulrich, G.2
Taupenot, L.3
Chasserot-Golaz, S.4
Corti, A.5
Aunis, D.6
Bader, M.F.7
-
12
-
-
10744228559
-
Identification of cathepsin B as a mediator of neuronal death induced by Aβ-activated microglial cells using a functional genomics approach
-
Gan L, Ye S, Chu A, Anton K, Yi S, Vincent VA, von Schack D, Chin D, Murray J, Lohr S, Patthy L, Gonzalez-Zulueta M, Nikolich K, Urfer R. 2004. Identification of cathepsin B as a mediator of neuronal death induced by Aβ-activated microglial cells using a functional genomics approach. J Biol Chem 279:5565-5572.
-
(2004)
J Biol Chem
, vol.279
, pp. 5565-5572
-
-
Gan, L.1
Ye, S.2
Chu, A.3
Anton, K.4
Yi, S.5
Vincent, V.A.6
von Schack, D.7
Chin, D.8
Murray, J.9
Lohr, S.10
Patthy, L.11
Gonzalez-Zulueta, M.12
Nikolich, K.13
Urfer, R.14
-
13
-
-
26944442371
-
Improvement of memory for context by inhibition of caspase-1 in aged rats
-
Gemma C, Fister M, Hudson C, Bickford PC. 2005. Improvement of memory for context by inhibition of caspase-1 in aged rats. Eur J Neurosci 22:1751-1756.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 1751-1756
-
-
Gemma, C.1
Fister, M.2
Hudson, C.3
Bickford, P.C.4
-
14
-
-
33750480549
-
The age-related attenuation in long-term potentiation is associated with microglial activation
-
Griffin R, Nally R, Nolan Y, McCartney Y, Linden J, Lynch MA. 2006. The age-related attenuation in long-term potentiation is associated with microglial activation. J Neurochem 99:1263-1272.
-
(2006)
J Neurochem
, vol.99
, pp. 1263-1272
-
-
Griffin, R.1
Nally, R.2
Nolan, Y.3
McCartney, Y.4
Linden, J.5
Lynch, M.A.6
-
15
-
-
34249795149
-
Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain
-
Guo W, Wang H, Watanabe M, Shimizu K, Zou S, LaGraize SC, Wei F, Dubner R, Ren K. 2007. Glial-cytokine-neuronal interactions underlying the mechanisms of persistent pain. J Neurosci 27:6006-6018.
-
(2007)
J Neurosci
, vol.27
, pp. 6006-6018
-
-
Guo, W.1
Wang, H.2
Watanabe, M.3
Shimizu, K.4
Zou, S.5
LaGraize, S.C.6
Wei, F.7
Dubner, R.8
Ren, K.9
-
16
-
-
0033795691
-
Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis
-
Halangk W, Lerch MM, Brandt-Nedelev B, Roth W, Ruthenbuerger M, Reinheckel T, Domschke W, Lippert H, Peters C, Deussing J. 2000. Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis. J Clin Invest 106:773-781.
-
(2000)
J Clin Invest
, vol.106
, pp. 773-781
-
-
Halangk, W.1
Lerch, M.M.2
Brandt-Nedelev, B.3
Roth, W.4
Ruthenbuerger, M.5
Reinheckel, T.6
Domschke, W.7
Lippert, H.8
Peters, C.9
Deussing, J.10
-
17
-
-
47849085872
-
The NALP3 inflammasome is involved in the innate immune response to amyloidβ
-
Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT. 2008. The NALP3 inflammasome is involved in the innate immune response to amyloidβ. Nat Immunol 9:857-865.
-
(2008)
Nat Immunol
, vol.9
, pp. 857-865
-
-
Halle, A.1
Hornung, V.2
Petzold, G.C.3
Stewart, C.R.4
Monks, B.G.5
Reinheckel, T.6
Fitzgerald, K.A.7
Latz, E.8
Moore, K.J.9
Golenbock, D.T.10
-
18
-
-
0034805342
-
Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis
-
Hashimoto Y, Kakegawa H, Narita Y, Hachiya Y, Hayakawa T, Kos J, Turk V, Katunuma N. 2001. Significance of cathepsin B accumulation in synovial fluid of rheumatoid arthritis. Biochem Biophys Res Commun 282:334-339.
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 334-339
-
-
Hashimoto, Y.1
Kakegawa, H.2
Narita, Y.3
Hachiya, Y.4
Hayakawa, T.5
Kos, J.6
Turk, V.7
Katunuma, N.8
-
19
-
-
51649126499
-
Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor A in mice
-
Hayashi Y, Yoshida M, Yamato M, Ide T, Wu Z, Ochi-Shindou M, Kanki T, Kang D, Sunagawa K, Tsutsui H, Nakanishi H. 2008. Reverse of age-dependent memory impairment and mitochondrial DNA damage in microglia by an overexpression of human mitochondrial transcription factor A in mice. J Neurosci 28:8624-8634.
-
(2008)
J Neurosci
, vol.28
, pp. 8624-8634
-
-
Hayashi, Y.1
Yoshida, M.2
Yamato, M.3
Ide, T.4
Wu, Z.5
Ochi-Shindou, M.6
Kanki, T.7
Kang, D.8
Sunagawa, K.9
Tsutsui, H.10
Nakanishi, H.11
-
20
-
-
0042914359
-
Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin
-
Hentze H, Lin XY, Choi MSK, Porter AG. 2003. Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin. Cell Death Diff 10:956-968.
-
(2003)
Cell Death Diff
, vol.10
, pp. 956-968
-
-
Hentze, H.1
Lin, X.Y.2
Choi, M.S.K.3
Porter, A.G.4
-
21
-
-
40449126196
-
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain
-
Kawasaki Y, Xu ZZ, Wang X, Park JY, Zhuang ZY, Tan PH, Gao YJ, Roy K, Corfas G, Lo EH, Ji RR. 2008. Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain. Nat Med 14:331-336.
-
(2008)
Nat Med
, vol.14
, pp. 331-336
-
-
Kawasaki, Y.1
Xu, Z.Z.2
Wang, X.3
Park, J.Y.4
Zhuang, Z.Y.5
Tan, P.H.6
Gao, Y.J.7
Roy, K.8
Corfas, G.9
Lo, E.H.10
Ji, R.R.11
-
22
-
-
0032788880
-
Apoptotic pathways mobilized in microglia and neurons as a consequence of chromogranin A-induced microglial activation
-
Kingham PJ, Cuzner ML, Pocock JM. 1999. Apoptotic pathways mobilized in microglia and neurons as a consequence of chromogranin A-induced microglial activation. J Neurochem 73:538-547.
-
(1999)
J Neurochem
, vol.73
, pp. 538-547
-
-
Kingham, P.J.1
Cuzner, M.L.2
Pocock, J.M.3
-
23
-
-
0034022078
-
Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarization and permeability transition but not by cytochrome c release
-
Kingham PJ, Pocock JM. 2000. Microglial apoptosis induced by chromogranin A is mediated by mitochondrial depolarization and permeability transition but not by cytochrome c release. J Neurochem 74:1452-1462.
-
(2000)
J Neurochem
, vol.74
, pp. 1452-1462
-
-
Kingham, P.J.1
Pocock, J.M.2
-
24
-
-
0035096992
-
Microglial secreted cathepsin B induces neuronal apoptosis
-
Kingham PJ, Pocock JM. 2001. Microglial secreted cathepsin B induces neuronal apoptosis. J Neurochem 76:1475-1484.
-
(2001)
J Neurochem
, vol.76
, pp. 1475-1484
-
-
Kingham, P.J.1
Pocock, J.M.2
-
25
-
-
0037301337
-
Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice
-
Koike M, Shibata M, Ohsawa Y, Nakanishi H, Koga T, Kametaka S, Waguri S, Momoi T, Kominami E, Saftig P, Peters C, Kurt von Figura, Uchiyama Y. 2003. Involvement of two different cell death pathways in retinal atrophy of cathepsin D-deficient mice. Mol Cell Neurosci 22:146-161.
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 146-161
-
-
Koike, M.1
Shibata, M.2
Ohsawa, Y.3
Nakanishi, H.4
Koga, T.5
Kametaka, S.6
Waguri, S.7
Momoi, T.8
Kominami, E.9
Saftig, P.10
Peters, C.11
Kurt von Figura, U.Y.12
-
26
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1β
-
Martinon F, Burns K, Tschopp J. 2002. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-1β. Mol Cell 10:417-426.
-
(2002)
Mol Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
27
-
-
33748524564
-
Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease
-
Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L. 2006. Antiamyloidogenic and neuroprotective functions of cathepsin B: Implications for Alzheimer's disease. Neuron 51:703-714.
-
(2006)
Neuron
, vol.51
, pp. 703-714
-
-
Mueller-Steiner, S.1
Zhou, Y.2
Arai, H.3
Roberson, E.D.4
Sun, B.5
Chen, J.6
Wang, X.7
Yu, G.8
Esposito, L.9
Mucke, L.10
Gan, L.11
-
28
-
-
0038348526
-
Microglia functions and proteases
-
Nakanishi H. 2003. Microglia functions and proteases. Mol Neurobiol 27:163-176.
-
(2003)
Mol Neurobiol
, vol.27
, pp. 163-176
-
-
Nakanishi, H.1
-
29
-
-
0023653461
-
Intracellular transport and processing of lysosomal cathepsin B
-
Nishimura Y, Kato K. 1987. Intracellular transport and processing of lysosomal cathepsin B. Biochem Biophys Res Commun 148:254-259.
-
(1987)
Biochem Biophys Res Commun
, vol.148
, pp. 254-259
-
-
Nishimura, Y.1
Kato, K.2
-
30
-
-
0037085460
-
Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia
-
Nishioku T, Hashimoto K, Yamashita K, Liou SY, Kagamiishi Y, Maegawa H, Katsube N, Peters C, von Figura K, Saftig P, Katunuma N, Yamamoto K, Nakanishi H. 2002. Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia. J Biol Chem 277:4816-4822.
-
(2002)
J Biol Chem
, vol.277
, pp. 4816-4822
-
-
Nishioku, T.1
Hashimoto, K.2
Yamashita, K.3
Liou, S.Y.4
Kagamiishi, Y.5
Maegawa, H.6
Katsube, N.7
Peters, C.8
von Figura, K.9
Saftig, P.10
Katunuma, N.11
Yamamoto, K.12
Nakanishi, H.13
-
31
-
-
34548614009
-
Nonclassical IL-1 βsecretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages
-
Qu Y, Franchi L, Nunez G, Dubyak GR. 2007. Nonclassical IL-1 βsecretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages. J Immunol 179:1913-1925.
-
(2007)
J Immunol
, vol.179
, pp. 1913-1925
-
-
Qu, Y.1
Franchi, L.2
Nunez, G.3
Dubyak, G.R.4
-
32
-
-
0035932121
-
Interleukin-1β-mediated induction of cox-2 in the CNS contributes to inflammatory pain hypersensitivity
-
Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. 2001. Interleukin-1β-mediated induction of cox-2 in the CNS contributes to inflammatory pain hypersensitivity. Nature 410:471-475.
-
(2001)
Nature
, vol.410
, pp. 471-475
-
-
Samad, T.A.1
Moore, K.A.2
Sapirstein, A.3
Billet, S.4
Allchorne, A.5
Poole, S.6
Bonventre, J.V.7
Woolf, C.J.8
-
33
-
-
0031980736
-
Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia
-
Sastradipura DF, Nakanishi H, Tsukuba T, Nishishita K, Sakai H, Kato Y, Gotow T, Uchiyama Y, Yamamoto K. 1998. Identification of cellular compartments involved in processing of cathepsin E in primary cultures of rat microglia. J Neurochem 70:2045-2056.
-
(1998)
J Neurochem
, vol.70
, pp. 2045-2056
-
-
Sastradipura, D.F.1
Nakanishi, H.2
Tsukuba, T.3
Nishishita, K.4
Sakai, H.5
Kato, Y.6
Gotow, T.7
Uchiyama, Y.8
Yamamoto, K.9
-
34
-
-
0028970610
-
The interleukin-1β-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasm ground substance of human monocytes by immunoelectron microscopy
-
Singer II, Scott S, Chin J, Bayne EK, Limjuco G, Weidner J, Miller DK, Chapman K, Kostura MJ. 1995. The interleukin-1β-converting enzyme (ICE) is localized on the external cell surface membranes and in the cytoplasm ground substance of human monocytes by immunoelectron microscopy. J Exp Med 182:1447-1459.
-
(1995)
J Exp Med
, vol.182
, pp. 1447-1459
-
-
Singer, I.I.1
Scott, S.2
Chin, J.3
Bayne, E.K.4
Limjuco, G.5
Weidner, J.6
Miller, D.K.7
Chapman, K.8
Kostura, M.J.9
-
35
-
-
0031793017
-
Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
-
Vancompernolle K, Van Herreweghe F, Pynaert G, Van de Craen M, De Vos K, Totty N, Sterling A, Fiers W, Vandenabeele P, Grooten J. 1998. Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. FEBS Lett 438:150-158.
-
(1998)
FEBS Lett
, vol.438
, pp. 150-158
-
-
Vancompernolle, K.1
Van Herreweghe, F.2
Pynaert, G.3
Van de Craen, M.4
De Vos, K.5
Totty, N.6
Sterling, A.7
Fiers, W.8
Vandenabeele, P.9
Grooten, J.10
-
36
-
-
0029047083
-
Qualitative and quantitative differences in senile plaque dystrophic neuritis of Alzheimer's disease and normal aged brain
-
Wang D, Munoz DG. 1995. Qualitative and quantitative differences in senile plaque dystrophic neuritis of Alzheimer's disease and normal aged brain. J Neuropathol Exp Neurol 54:548-556.
-
(1995)
J Neuropathol Exp Neurol
, vol.54
, pp. 548-556
-
-
Wang, D.1
Munoz, D.G.2
-
37
-
-
0035869183
-
Chloroquine antagonizes the proinflammatory cytokine response to opportunistic fungi by alkalizing the fungal phagolysosome
-
Weber SM, Levitz SM. 2001. Chloroquine antagonizes the proinflammatory cytokine response to opportunistic fungi by alkalizing the fungal phagolysosome. J Infect Dis 183:935-942.
-
(2001)
J Infect Dis
, vol.183
, pp. 935-942
-
-
Weber, S.M.1
Levitz, S.M.2
|