Granzyme K synergistically potentiates LPS-induced cytokine responses in human monocytes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 16, 2014, Pages 5974-5979

  Wensink, Annette C ^a   Kemp, Vera ^a   Fermie, Job ^a   Laorden, M Isabel García ^b   Van Der Poll, Tom ^b   Hack, C Erik ^a   Bovenschen, Niels ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME K; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; SERINE PROTEINASE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BACTERIAL CELL WALL; BACTERIAL INFECTION; COMPLEX FORMATION; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME BINDING; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE SEPSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MICELLE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD14; CYTOKINES; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRANZYMES; HUMANS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MICE; MICELLES; MONOCYTES; PROTEIN BINDING; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84899072761     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1317347111     Document Type: Article

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