메뉴 건너뛰기




Volumn 18, Issue 7, 2011, Pages 1112-1119

Mouse granzyme K has pro-inflammatory potential

Author keywords

inflammation; orphan granzymes; T killer cell; virus control

Indexed keywords

GRANZYME; GRANZYME A; GRANZYME B; GRANZYME K; INTERLEUKIN 1BETA; PROTEINASE; PURINERGIC P2X7 RECEPTOR; RECOMBINANT INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

EID: 79958780641     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.5     Document Type: Article
Times cited : (83)

References (44)
  • 1
    • 0036595397 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes: All roads lead to death
    • Barry M, Bleackley RC. Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol 2002; 2: 401-409. (Pubitemid 37328747)
    • (2002) Nature Reviews Immunology , vol.2 , Issue.6 , pp. 401-409
    • Barry, M.1    Bleackley, R.C.2
  • 3
    • 45949131449 scopus 로고
    • Are proteinases functional molecules of T cells?
    • Kramer M, Simon MM. Are proteinases functional molecules of T cells? Immunol Today 1987; 8: 140-143.
    • (1987) Immunol Today , vol.8 , pp. 140-143
    • Kramer, M.1    Simon, M.M.2
  • 4
    • 0024416820 scopus 로고
    • Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A
    • Hayes MP, Berrebi GA, Henkart PA. Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A. J Exp Med 1989; 170: 933-946. (Pubitemid 19226674)
    • (1989) Journal of Experimental Medicine , vol.170 , Issue.3 , pp. 933-946
    • Hayes, M.P.1    Berrebi, G.A.2    Henkart, P.A.3
  • 5
    • 0026532606 scopus 로고
    • A natural killer cell granule protein that induces DNA fragmentation and apoptosis
    • Shi L, Kraut RP, Aebersold R, Greenberg AH. A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J Exp Med 1992; 175: 553-566.
    • (1992) J Exp Med , vol.175 , pp. 553-566
    • Shi, L.1    Kraut, R.P.2    Aebersold, R.3    Greenberg, A.H.4
  • 6
    • 0029963625 scopus 로고    scopus 로고
    • Extracellular activities of human granzyme A: Monocyte activation by granzyme A versus α-thrombin
    • Sower LE, Froelich CJ, Allegretto N, Rose PM, Hanna WD, Klimpel GR. Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alphathrombin. J Immunol 1996; 156: 2585-2590. (Pubitemid 26093702)
    • (1996) Journal of Immunology , vol.156 , Issue.7 , pp. 2585-2590
    • Sower, L.E.1    Froelich, C.J.2    Allegretto, N.3    Rose, P.M.4    Hanna, W.D.5    Klimpel, G.R.6
  • 9
    • 0033137079 scopus 로고    scopus 로고
    • Granzyme a loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation
    • DOI 10.1016/S1074-7613(00)80058-8
    • Beresford PJ, Xia Z, Greenberg AH, Lieberman J. Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation. Immunity 1999; 10: 585-594. (Pubitemid 29262661)
    • (1999) Immunity , vol.10 , Issue.5 , pp. 585-594
    • Beresford, P.J.1    Xia, Z.2    Greenberg, A.H.3    Lieberman, J.4
  • 10
    • 33845890803 scopus 로고    scopus 로고
    • Inflammasome adaptors and sensors: Intracellular regulators of infection and inflammation
    • DOI 10.1038/nri1997, PII NRI1997
    • Mariathasan S, Monack DM. Inflammasome adaptors and sensors: intracellular regulators of infection and inflammation. Nat Rev Immunol 2007; 7: 31-40. (Pubitemid 46020825)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.1 , pp. 31-40
    • Mariathasan, S.1    Monack, D.M.2
  • 11
    • 77956417182 scopus 로고    scopus 로고
    • A role for granzyme M in TLR4-driven inflammation and endotoxicosis
    • Anthony DA, Andrews DM, Chow M, Watt SV, House C, Akira S et al. A role for granzyme M in TLR4-driven inflammation and endotoxicosis. J Immunol 2010; 185: 1794-1803.
    • (2010) J Immunol , vol.185 , pp. 1794-1803
    • Anthony, D.A.1    Andrews, D.M.2    Chow, M.3    Watt, S.V.4    House, C.5    Akira, S.6
  • 12
    • 63649099411 scopus 로고    scopus 로고
    • Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A
    • Bovenschen N, Quadir R, van den Berg AL, Brenkman AB, Vandenberghe I, Devreese B et al. Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A. J Biol Chem 2009; 284: 3504-3512.
    • (2009) J Biol Chem , vol.284 , pp. 3504-3512
    • Bovenschen, N.1    Quadir, R.2    Van Den Berg, A.L.3    Brenkman, A.B.4    Vandenberghe, I.5    Devreese, B.6
  • 13
    • 0026474805 scopus 로고
    • Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions
    • Shi L, Kam CM, Powers JC, Aebersold R, Greenberg AH. Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions. J Exp Med 1992; 176: 1521-1529.
    • (1992) J Exp Med , vol.176 , pp. 1521-1529
    • Shi, L.1    Kam, C.M.2    Powers, J.C.3    Aebersold, R.4    Greenberg, A.H.5
  • 14
    • 34249721529 scopus 로고    scopus 로고
    • Granzyme K directly processes bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death
    • DOI 10.1074/jbc.M611006200
    • Zhao T, Zhang H, Guo Y, Fan Z. Granzyme K directly processes Bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death. J Biol Chem 2007; 282: 12104-12111. (Pubitemid 47100717)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.16 , pp. 12104-12111
    • Zhao, T.1    Zhang, H.2    Guo, Y.3    Fan, Z.4
  • 15
    • 33847054267 scopus 로고    scopus 로고
    • Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells
    • Zhao T, Zhang H, Guo Y, Zhang Q, Hua G, Lu H et al. Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells. Cell Death Differ 2007; 14: 489-499.
    • (2007) Cell Death Differ , vol.14 , pp. 489-499
    • Zhao, T.1    Zhang, H.2    Guo, Y.3    Zhang, Q.4    Hua, G.5    Lu, H.6
  • 16
    • 40149091820 scopus 로고    scopus 로고
    • Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity
    • Guo Y, Chen J, Zhao T, Fan Z. Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity. Mol Immunol 2008; 45: 2225-2235.
    • (2008) Mol Immunol , vol.45 , pp. 2225-2235
    • Guo, Y.1    Chen, J.2    Zhao, T.3    Fan, Z.4
  • 17
    • 61449210797 scopus 로고    scopus 로고
    • Ignition of p53 bomb sensitizes tumor cells to granzyme K-mediated cytolysis
    • Hua G, Wang S, Zhong C, Xue P, Fan Z. Ignition of p53 bomb sensitizes tumor cells to granzyme K-mediated cytolysis. J Immunol 2009; 182: 2152-2159.
    • (2009) J Immunol , vol.182 , pp. 2152-2159
    • Hua, G.1    Wang, S.2    Zhong, C.3    Xue, P.4    Fan, Z.5
  • 18
    • 78149474336 scopus 로고    scopus 로고
    • Valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells
    • Guo Y, Chen J, Shi L, Fan Z. Valosin-containing protein cleavage by granzyme K accelerates an endoplasmic reticulum stress leading to caspase-independent cytotoxicity of target tumor cells. J Immunol 2010; 185: 5348-5359.
    • (2010) J Immunol , vol.185 , pp. 5348-5359
    • Guo, Y.1    Chen, J.2    Shi, L.3    Fan, Z.4
  • 20
    • 34247262710 scopus 로고    scopus 로고
    • Altered levels and molecular forms of granzyme K in plasma from septic patients
    • DOI 10.1097/01.shk.0000246905.24895.e5, PII 0002438220070500000006
    • Rucevic M, Fast LD, Jay GD, Trespalcios FM, Sucov A, Siryaporn E et al. Altered levels and molecular forms of granzyme K in plasma from septic patients. Shock 2007; 27: 488-493. (Pubitemid 46626075)
    • (2007) Shock , vol.27 , Issue.5 , pp. 488-493
    • Rucevic, M.1    Fast, L.D.2    Jay, G.D.3    Trespalcios, F.M.4    Sucov, A.5    Siryaporn, E.6    Lim, Y.-P.7
  • 24
    • 0037230088 scopus 로고    scopus 로고
    • Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice
    • DOI 10.1006/viro.2002.1754
    • Zajac AJ, Dye JM, Quinn DG. Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice. Virology 2003; 305: 1-9. (Pubitemid 36062806)
    • (2003) Virology , vol.305 , Issue.1 , pp. 1-9
    • Zajac, A.J.1    Dye, J.M.2    Quinn, D.G.3
  • 26
    • 34250846385 scopus 로고    scopus 로고
    • Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL
    • Jenkins MR, Kedzierska K, Doherty PC, Turner SJ. Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL. J Immunol 2007; 179: 64-70. (Pubitemid 46986518)
    • (2007) Journal of Immunology , vol.179 , Issue.1 , pp. 64-70
    • Jenkins, M.R.1    Kedzierska, K.2    Doherty, P.C.3    Turner, S.J.4
  • 27
    • 51849108216 scopus 로고    scopus 로고
    • Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB(+) mice
    • Jenkins MR, Trapani JA, Doherty PC, Turner SJ. Granzyme K expressing cytotoxic T lymphocytes protects against influenza virus in granzyme AB(+) mice. Viral Immunol 2008; 21: 341-346.
    • (2008) Viral Immunol , vol.21 , pp. 341-346
    • Jenkins, M.R.1    Trapani, J.A.2    Doherty, P.C.3    Turner, S.J.4
  • 29
    • 67649639047 scopus 로고    scopus 로고
    • Signaling at purinergic P2X receptors
    • Surprenant A, North RA. Signaling at purinergic P2X receptors. Annu Rev Physiol 2009; 71: 333-359.
    • (2009) Annu Rev Physiol , vol.71 , pp. 333-359
    • Surprenant, A.1    North, R.A.2
  • 30
    • 66749174867 scopus 로고    scopus 로고
    • The inflammasomes: Guardians of the body
    • Martinon F, Mayor A, Tschopp J. The inflammasomes: guardians of the body. Annu Rev Immunol 2009; 27: 229-265.
    • (2009) Annu Rev Immunol , vol.27 , pp. 229-265
    • Martinon, F.1    Mayor, A.2    Tschopp, J.3
  • 32
    • 8444249247 scopus 로고    scopus 로고
    • Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis
    • DOI 10.1083/jcb.200406115
    • Pardo J, Bosque A, Brehm R, Wallich R, Naval J, Mullbacher A et al. Apoptotic pathways are selectively activated by granzyme A and/or granzyme B in CTL-mediated target cell lysis. J Cell Biol 2004; 167: 457-468. (Pubitemid 39489054)
    • (2004) Journal of Cell Biology , vol.167 , Issue.3 , pp. 457-468
    • Pardo, J.1    Bosque, A.2    Brehm, R.3    Wallich, R.4    Naval, J.5    Mullbacher, A.6    Anel, A.7    Simon, M.M.8
  • 33
    • 64549090599 scopus 로고    scopus 로고
    • The biology of cytotoxic cell granule exocytosis pathway: Granzymes have evolved to induce cell death and inflammation
    • Pardo J, Aguilo JI, Anel A, Martin P, Joeckel L, Borner C et al. The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation. Microbes Infect 2009; 11: 452-459.
    • (2009) Microbes Infect , vol.11 , pp. 452-459
    • Pardo, J.1    Aguilo, J.I.2    Anel, A.3    Martin, P.4    Joeckel, L.5    Borner, C.6
  • 34
    • 42949098879 scopus 로고    scopus 로고
    • Death by a thousand cuts: Granzyme pathways of programmed cell death
    • DOI 10.1146/annurev.immunol.26.021607.090404
    • Chowdhury D, Lieberman J. Death by a thousand cuts: granzyme pathways of programmed cell death. Annu Rev Immunol 2008; 26: 389-420. (Pubitemid 351611623)
    • (2008) Annual Review of Immunology , vol.26 , pp. 389-420
    • Chowdhury, D.1    Lieberman, J.2
  • 35
    • 61349091649 scopus 로고    scopus 로고
    • Granule-associated serine proteases: Granzymes might not just be killer proteases
    • Froelich CJ, Pardo J, Simon MM. Granule-associated serine proteases: granzymes might not just be killer proteases. Trends Immunol 2009; 30: 117-123.
    • (2009) Trends Immunol , vol.30 , pp. 117-123
    • Froelich, C.J.1    Pardo, J.2    Simon, M.M.3
  • 36
    • 34247261939 scopus 로고    scopus 로고
    • Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition
    • DOI 10.1038/sj.emboj.7601650, PII 7601650
    • Andrade F, Fellows E, Jenne DE, Rosen A, Young CS. Granzyme H destroys the function of critical adenoviral proteins required for viral DNA replication and granzyme B inhibition. EMBO J 2007; 26: 2148-2157. (Pubitemid 46625785)
    • (2007) EMBO Journal , vol.26 , Issue.8 , pp. 2148-2157
    • Andrade, F.1    Fellows, E.2    Jenne, D.E.3    Rosen, A.4    Young, C.S.H.5
  • 37
    • 60549112774 scopus 로고    scopus 로고
    • Inflammasome recognition of influenza virus is essential for adaptive immune responses
    • Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A. Inflammasome recognition of influenza virus is essential for adaptive immune responses. J Exp Med 2009; 206: 79-87.
    • (2009) J Exp Med , vol.206 , pp. 79-87
    • Ichinohe, T.1    Lee, H.K.2    Ogura, Y.3    Flavell, R.4    Iwasaki, A.5
  • 38
    • 0033598718 scopus 로고    scopus 로고
    • Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
    • Mullbacher A, Waring P, Tha Hla R, Tran T, Chin S, Stehle T et al. Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes. Proc Natl Acad Sci USA 1999; 96: 13950-13955.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 13950-13955
    • Mullbacher, A.1    Waring, P.2    Tha Hla, R.3    Tran, T.4    Chin, S.5    Stehle, T.6
  • 40
    • 27144526642 scopus 로고    scopus 로고
    • Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: Similarities or differences with human polymorphonuclear leukocytes?
    • DOI 10.1182/blood-2005-04-1522
    • Martin P, Wallich R, Pardo J, Mullbacher A, Munder M, Modolell M et al. Quiescent and activated mouse granulocytes do not express granzyme A and B or perforin: similarities or differences with human polymorphonuclear leukocytes? Blood 2005; 106: 2871-2878. (Pubitemid 41510767)
    • (2005) Blood , vol.106 , Issue.8 , pp. 2871-2878
    • Martin, P.1    Wallich, R.2    Pardo, J.3    Mullbacher, A.4    Munder, M.5    Modolell, M.6    Simon, M.M.7
  • 41
    • 0033578756 scopus 로고    scopus 로고
    • Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma
    • Wilharm E, Parry MA, Friebel R, Tschesche H, Matschiner G, Sommerhoff CP et al. Generation of catalytically active granzyme K from Escherichia coli inclusion bodies and identification of efficient granzyme K inhibitors in human plasma. J Biol Chem 1999; 274: 27331-27337.
    • (1999) J Biol Chem , vol.274 , pp. 27331-27337
    • Wilharm, E.1    Parry, M.A.2    Friebel, R.3    Tschesche, H.4    Matschiner, G.5    Sommerhoff, C.P.6
  • 42
    • 0036312429 scopus 로고    scopus 로고
    • The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells
    • DOI 10.1002/1521-4141(200207)32:7<1980::AID-IMMU1980>3.0.CO;2-Z
    • Pardo J, Balkow S, Anel A, Simon MM. The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells. Eur J Immunol 2002; 32: 1980-1985. (Pubitemid 34814554)
    • (2002) European Journal of Immunology , vol.32 , Issue.7 , pp. 1980-1985
    • Pardo, J.1    Balkow, S.2    Anel, A.3    Simon, M.M.4
  • 43
    • 0022962214 scopus 로고
    • Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes
    • Simon MM, Hoschutzky H, Fruth U, Simon HG, Kramer MD. Purification and characterization of a T cell specific serine proteinase (TSP-1) from cloned cytolytic T lymphocytes. EMBO J 1986; 5: 3267-3274.
    • (1986) EMBO J , vol.5 , pp. 3267-3274
    • Simon, M.M.1    Hoschutzky, H.2    Fruth, U.3    Simon, H.G.4    Kramer, M.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.