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Volumn 6, Issue 6, 2011, Pages

Granzyme K activates protease-activated receptor-1

Author keywords

[No Author keywords available]

Indexed keywords

GRANZYME; GRANZYME K; INTERLEUKIN 6; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; UNCLASSIFIED DRUG; CCL2 PROTEIN, HUMAN; THROMBIN;

EID: 79959711672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0021484     Document Type: Article
Times cited : (63)

References (52)
  • 2
    • 77949529810 scopus 로고    scopus 로고
    • Granzyme B cleavage of autoantigens in autoimmunity
    • Darrah E, Rosen A, (2010) Granzyme B cleavage of autoantigens in autoimmunity. Cell Death Differ 17: 624-632.
    • (2010) Cell Death Differ , vol.17 , pp. 624-632
    • Darrah, E.1    Rosen, A.2
  • 3
    • 61349091649 scopus 로고    scopus 로고
    • Granule-associated serine proteases: granzymes might not just be killer proteases
    • Froelich CJ, Pardo J, Simon MM, (2009) Granule-associated serine proteases: granzymes might not just be killer proteases. Trends Immunol 30: 117-123.
    • (2009) Trends Immunol , vol.30 , pp. 117-123
    • Froelich, C.J.1    Pardo, J.2    Simon, M.M.3
  • 4
    • 77949521217 scopus 로고    scopus 로고
    • Granzymes in disease: bench to bedside
    • Granville DJ, (2010) Granzymes in disease: bench to bedside. Cell Death Differ 17: 565-566.
    • (2010) Cell Death Differ , vol.17 , pp. 565-566
    • Granville, D.J.1
  • 6
    • 79959742434 scopus 로고    scopus 로고
    • Granzyme B Contributes to Extracellular Matrix Remodelling and Skin Aging in Apolipoprotein E Knockout Mice
    • Hiebert PR, Boivin WA, Abraham T, Pazooki S, Zhao H, et al. (2010) Granzyme B Contributes to Extracellular Matrix Remodelling and Skin Aging in Apolipoprotein E Knockout Mice. Exp Gerontol.
    • (2010) Exp Gerontol
    • Hiebert, P.R.1    Boivin, W.A.2    Abraham, T.3    Pazooki, S.4    Zhao, H.5
  • 8
    • 55349138368 scopus 로고    scopus 로고
    • Human and mouse granzyme A induce a proinflammatory cytokine response
    • Metkar SS, Menaa C, Pardo J, Wang B, Wallich R, et al. (2008) Human and mouse granzyme A induce a proinflammatory cytokine response. Immunity 29: 720-733.
    • (2008) Immunity , vol.29 , pp. 720-733
    • Metkar, S.S.1    Menaa, C.2    Pardo, J.3    Wang, B.4    Wallich, R.5
  • 9
    • 70350627504 scopus 로고    scopus 로고
    • Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma
    • Boivin WA, Cooper DM, Hiebert PR, Granville DJ, (2009) Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma. Lab Invest 89: 1195-1220.
    • (2009) Lab Invest , vol.89 , pp. 1195-1220
    • Boivin, W.A.1    Cooper, D.M.2    Hiebert, P.R.3    Granville, D.J.4
  • 10
    • 56049105428 scopus 로고    scopus 로고
    • Granzyme K: a novel mediator in acute airway inflammation
    • Bratke K, Klug A, Julius P, Kuepper M, Lommatzsch M, et al. (2008) Granzyme K: a novel mediator in acute airway inflammation. Thorax 63: 1006-1011.
    • (2008) Thorax , vol.63 , pp. 1006-1011
    • Bratke, K.1    Klug, A.2    Julius, P.3    Kuepper, M.4    Lommatzsch, M.5
  • 11
    • 34247262710 scopus 로고    scopus 로고
    • Altered levels and molecular forms of granzyme k in plasma from septic patients
    • Rucevic M, Fast LD, Jay GD, Trespalcios FM, Sucov A, et al. (2007) Altered levels and molecular forms of granzyme k in plasma from septic patients. Shock 27: 488-493.
    • (2007) Shock , vol.27 , pp. 488-493
    • Rucevic, M.1    Fast, L.D.2    Jay, G.D.3    Trespalcios, F.M.4    Sucov, A.5
  • 12
    • 0027997472 scopus 로고
    • Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue
    • Tak PP, Kummer JA, Hack CE, Daha MR, Smeets TJ, et al. (1994) Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue. Arthritis Rheum 37: 1735-1743.
    • (1994) Arthritis Rheum , vol.37 , pp. 1735-1743
    • Tak, P.P.1    Kummer, J.A.2    Hack, C.E.3    Daha, M.R.4    Smeets, T.J.5
  • 13
    • 0032895417 scopus 로고    scopus 로고
    • The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA)
    • Tak PP, Spaeny-Dekking L, Kraan MC, Breedveld FC, Froelich CJ, et al. (1999) The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA). Clin Exp Immunol 116: 366-370.
    • (1999) Clin Exp Immunol , vol.116 , pp. 366-370
    • Tak, P.P.1    Spaeny-Dekking, L.2    Kraan, M.C.3    Breedveld, F.C.4    Froelich, C.J.5
  • 14
    • 33847681925 scopus 로고    scopus 로고
    • Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease
    • Vernooy JH, Moller GM, van Suylen RJ, van Spijk MP, Cloots RH, et al. (2007) Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 175: 464-472.
    • (2007) Am J Respir Crit Care Med , vol.175 , pp. 464-472
    • Vernooy, J.H.1    Moller, G.M.2    van Suylen, R.J.3    van Spijk, M.P.4    Cloots, R.H.5
  • 16
    • 0141617467 scopus 로고    scopus 로고
    • Correlation between mortality and the levels of inter-alpha inhibitors in the plasma of patients with severe sepsis
    • Lim YP, Bendelja K, Opal SM, Siryaporn E, Hixson DC, et al. (2003) Correlation between mortality and the levels of inter-alpha inhibitors in the plasma of patients with severe sepsis. J Infect Dis 188: 919-926.
    • (2003) J Infect Dis , vol.188 , pp. 919-926
    • Lim, Y.P.1    Bendelja, K.2    Opal, S.M.3    Siryaporn, E.4    Hixson, D.C.5
  • 17
    • 77955624600 scopus 로고    scopus 로고
    • Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice
    • Singh K, Zhang LX, Bendelja K, Heath R, Murphy S, et al. (2010) Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice. Pediatr Res 68: 242-247.
    • (2010) Pediatr Res , vol.68 , pp. 242-247
    • Singh, K.1    Zhang, L.X.2    Bendelja, K.3    Heath, R.4    Murphy, S.5
  • 18
    • 40149091820 scopus 로고    scopus 로고
    • Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity
    • Guo Y, Chen J, Zhao T, Fan Z, (2008) Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity. Mol Immunol 45: 2225-2235.
    • (2008) Mol Immunol , vol.45 , pp. 2225-2235
    • Guo, Y.1    Chen, J.2    Zhao, T.3    Fan, Z.4
  • 19
    • 34249721529 scopus 로고    scopus 로고
    • Granzyme K directly processes bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death
    • Zhao T, Zhang H, Guo Y, Fan Z, (2007) Granzyme K directly processes bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death. J Biol Chem 282: 12104-12111.
    • (2007) J Biol Chem , vol.282 , pp. 12104-12111
    • Zhao, T.1    Zhang, H.2    Guo, Y.3    Fan, Z.4
  • 20
    • 33847054267 scopus 로고    scopus 로고
    • Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells
    • Zhao T, Zhang H, Guo Y, Zhang Q, Hua G, et al. (2007) Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells. Cell Death Differ 14: 489-499.
    • (2007) Cell Death Differ , vol.14 , pp. 489-499
    • Zhao, T.1    Zhang, H.2    Guo, Y.3    Zhang, Q.4    Hua, G.5
  • 21
    • 0026532606 scopus 로고
    • A natural killer cell granule protein that induces DNA fragmentation and apoptosis
    • Shi L, Kraut RP, Aebersold R, Greenberg AH, (1992) A natural killer cell granule protein that induces DNA fragmentation and apoptosis. J Exp Med 175: 553-566.
    • (1992) J Exp Med , vol.175 , pp. 553-566
    • Shi, L.1    Kraut, R.P.2    Aebersold, R.3    Greenberg, A.H.4
  • 22
    • 63649099411 scopus 로고    scopus 로고
    • Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A
    • Bovenschen N, Quadir R, van den Berg AL, Brenkman AB, Vandenberghe I, et al. (2009) Granzyme K displays highly restricted substrate specificity that only partially overlaps with granzyme A. J Biol Chem 284: 3504-3512.
    • (2009) J Biol Chem , vol.284 , pp. 3504-3512
    • Bovenschen, N.1    Quadir, R.2    van den Berg, A.L.3    Brenkman, A.B.4    Vandenberghe, I.5
  • 24
    • 0029963625 scopus 로고    scopus 로고
    • Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin
    • Sower LE, Froelich CJ, Allegretto N, Rose PM, Hanna WD, et al. (1996) Extracellular activities of human granzyme A. Monocyte activation by granzyme A versus alpha-thrombin. J Immunol 156: 2585-2590.
    • (1996) J Immunol , vol.156 , pp. 2585-2590
    • Sower, L.E.1    Froelich, C.J.2    Allegretto, N.3    Rose, P.M.4    Hanna, W.D.5
  • 25
    • 0030578437 scopus 로고    scopus 로고
    • Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines
    • Sower LE, Klimpel GR, Hanna W, Froelich CJ, (1996) Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines. Cell Immunol 171: 159-163.
    • (1996) Cell Immunol , vol.171 , pp. 159-163
    • Sower, L.E.1    Klimpel, G.R.2    Hanna, W.3    Froelich, C.J.4
  • 26
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: contribution to physiology and disease
    • Ossovskaya VS, Bunnett NW, (2004) Protease-activated receptors: contribution to physiology and disease. Physiol Rev 84: 579-621.
    • (2004) Physiol Rev , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 27
    • 13444249470 scopus 로고    scopus 로고
    • Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response
    • Steinhoff M, Buddenkotte J, Shpacovitch V, Rattenholl A, Moormann C, et al. (2005) Proteinase-activated receptors: transducers of proteinase-mediated signaling in inflammation and immune response. Endocr Rev 26: 1-43.
    • (2005) Endocr Rev , vol.26 , pp. 1-43
    • Steinhoff, M.1    Buddenkotte, J.2    Shpacovitch, V.3    Rattenholl, A.4    Moormann, C.5
  • 28
    • 45949100430 scopus 로고    scopus 로고
    • Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity
    • Shpacovitch V, Feld M, Hollenberg MD, Luger TA, Steinhoff M, (2008) Role of protease-activated receptors in inflammatory responses, innate and adaptive immunity. J Leukoc Biol 83: 1309-1322.
    • (2008) J Leukoc Biol , vol.83 , pp. 1309-1322
    • Shpacovitch, V.1    Feld, M.2    Hollenberg, M.D.3    Luger, T.A.4    Steinhoff, M.5
  • 29
    • 7944224566 scopus 로고    scopus 로고
    • The role of protease activation of inflammation in allergic respiratory diseases
    • quiz 1009
    • Reed CE, Kita H, (2004) The role of protease activation of inflammation in allergic respiratory diseases. J Allergy Clin Immunol 114: 997-1008; quiz 1009.
    • (2004) J Allergy Clin Immunol , vol.114 , pp. 997-1008
    • Reed, C.E.1    Kita, H.2
  • 30
  • 31
    • 39549086998 scopus 로고    scopus 로고
    • Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation
    • Borensztajn K, Stiekema J, Nijmeijer S, Reitsma PH, Peppelenbosch MP, et al. (2008) Factor Xa stimulates proinflammatory and profibrotic responses in fibroblasts via protease-activated receptor-2 activation. Am J Pathol 172: 309-320.
    • (2008) Am J Pathol , vol.172 , pp. 309-320
    • Borensztajn, K.1    Stiekema, J.2    Nijmeijer, S.3    Reitsma, P.H.4    Peppelenbosch, M.P.5
  • 32
    • 0032126368 scopus 로고    scopus 로고
    • Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1
    • Chambers RC, Dabbagh K, McAnulty RJ, Gray AJ, Blanc-Brude OP, et al. (1998) Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1. Biochem J 333 (Pt 1): 121-127.
    • (1998) Biochem J , vol.333 , Issue.Pt 1 , pp. 121-127
    • Chambers, R.C.1    Dabbagh, K.2    McAnulty, R.J.3    Gray, A.J.4    Blanc-Brude, O.P.5
  • 34
    • 0034608013 scopus 로고    scopus 로고
    • Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1
    • O'Brien PJ, Prevost N, Molino M, Hollinger MK, Woolkalis MJ, et al. (2000) Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1. The Journal of biological chemistry 275: 13502-13509.
    • (2000) The Journal of Biological Chemistry , vol.275 , pp. 13502-13509
    • O'Brien, P.J.1    Prevost, N.2    Molino, M.3    Hollinger, M.K.4    Woolkalis, M.J.5
  • 35
    • 3543121913 scopus 로고    scopus 로고
    • Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis
    • Shi X, Gangadharan B, Brass LF, Ruf W, Mueller BM, (2004) Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Molecular cancer research: MCR 2: 395-402.
    • (2004) Molecular Cancer Research: MCR , vol.2 , pp. 395-402
    • Shi, X.1    Gangadharan, B.2    Brass, L.F.3    Ruf, W.4    Mueller, B.M.5
  • 37
    • 48749132865 scopus 로고    scopus 로고
    • Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways
    • Deng X, Mercer PF, Scotton CJ, Gilchrist A, Chambers RC, (2008) Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Galphaq and cooperation between ERK1/2 and Rho kinase signaling pathways. Mol Biol Cell 19: 2520-2533.
    • (2008) Mol Biol Cell , vol.19 , pp. 2520-2533
    • Deng, X.1    Mercer, P.F.2    Scotton, C.J.3    Gilchrist, A.4    Chambers, R.C.5
  • 38
    • 37549062234 scopus 로고    scopus 로고
    • Protease-activated receptor (PAR)-induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK
    • Ostrowska E, Reiser G, (2008) Protease-activated receptor (PAR)-induced interleukin-8 production in airway epithelial cells requires activation of MAP kinases p44/42 and JNK. Biochem Biophys Res Commun 366: 1030-1035.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 1030-1035
    • Ostrowska, E.1    Reiser, G.2
  • 39
    • 33646578168 scopus 로고    scopus 로고
    • Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts
    • Wang L, Luo J, Fu Y, He S, (2006) Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts. Int J Biochem Cell Biol 38: 1571-1583.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1571-1583
    • Wang, L.1    Luo, J.2    Fu, Y.3    He, S.4
  • 40
    • 23844461112 scopus 로고    scopus 로고
    • Functional analysis of granzyme M and its role in immunity to infection
    • Pao LI, Sumaria N, Kelly JM, van Dommelen S, Cretney E, et al. (2005) Functional analysis of granzyme M and its role in immunity to infection. J Immunol 175: 3235-3243.
    • (2005) J Immunol , vol.175 , pp. 3235-3243
    • Pao, L.I.1    Sumaria, N.2    Kelly, J.M.3    van Dommelen, S.4    Cretney, E.5
  • 41
    • 70449729720 scopus 로고    scopus 로고
    • Granzyme A is a proinflammatory protease
    • author reply 3969-3970
    • Pardo J, Simon MM, Froelich CJ, (2009) Granzyme A is a proinflammatory protease. Blood 114: 3968; author reply 3969-3970.
    • (2009) Blood , vol.114 , pp. 3968
    • Pardo, J.1    Simon, M.M.2    Froelich, C.J.3
  • 42
    • 0034034708 scopus 로고    scopus 로고
    • Thrombin upregulates interleukin-8 in lung fibroblasts via cleavage of proteolytically activated receptor-I and protein kinase C-gamma activation
    • Ludwicka-Bradley A, Tourkina E, Suzuki S, Tyson E, Bonner M, et al. (2000) Thrombin upregulates interleukin-8 in lung fibroblasts via cleavage of proteolytically activated receptor-I and protein kinase C-gamma activation. Am J Respir Cell Mol Biol 22: 235-243.
    • (2000) Am J Respir Cell Mol Biol , vol.22 , pp. 235-243
    • Ludwicka-Bradley, A.1    Tourkina, E.2    Suzuki, S.3    Tyson, E.4    Bonner, M.5
  • 43
    • 0026611673 scopus 로고
    • IL-6 and NF-IL6 in acute-phase response and viral infection
    • Akira S, Kishimoto T, (1992) IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev 127: 25-50.
    • (1992) Immunol Rev , vol.127 , pp. 25-50
    • Akira, S.1    Kishimoto, T.2
  • 44
    • 0029893140 scopus 로고    scopus 로고
    • Role of interleukin-6 in macrophage function
    • Akira S, Kishimoto T, (1996) Role of interleukin-6 in macrophage function. Curr Opin Hematol 3: 87-93.
    • (1996) Curr Opin Hematol , vol.3 , pp. 87-93
    • Akira, S.1    Kishimoto, T.2
  • 45
    • 1342346594 scopus 로고    scopus 로고
    • Caveolin-1 knockdown by small interfering RNA suppresses responses to the chemokine monocyte chemoattractant protein-1 by human astrocytes
    • Ge S, Pachter JS, (2004) Caveolin-1 knockdown by small interfering RNA suppresses responses to the chemokine monocyte chemoattractant protein-1 by human astrocytes. J Biol Chem 279: 6688-6695.
    • (2004) J Biol Chem , vol.279 , pp. 6688-6695
    • Ge, S.1    Pachter, J.S.2
  • 46
    • 0030014832 scopus 로고    scopus 로고
    • Costimulation of fibroblast collagen and transforming growth factor beta1 gene expression by monocyte chemoattractant protein-1 via specific receptors
    • Gharaee-Kermani M, Denholm EM, Phan SH, (1996) Costimulation of fibroblast collagen and transforming growth factor beta1 gene expression by monocyte chemoattractant protein-1 via specific receptors. J Biol Chem 271: 17779-17784.
    • (1996) J Biol Chem , vol.271 , pp. 17779-17784
    • Gharaee-Kermani, M.1    Denholm, E.M.2    Phan, S.H.3
  • 49
    • 0034672092 scopus 로고    scopus 로고
    • Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun
    • Georganas C, Liu H, Perlman H, Hoffmann A, Thimmapaya B, et al. (2000) Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun. J Immunol 165: 7199-7206.
    • (2000) J Immunol , vol.165 , pp. 7199-7206
    • Georganas, C.1    Liu, H.2    Perlman, H.3    Hoffmann, A.4    Thimmapaya, B.5
  • 50
    • 14644402494 scopus 로고    scopus 로고
    • CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury
    • Moore BB, Kolodsick JE, Thannickal VJ, Cooke K, Moore TA, et al. (2005) CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury. Am J Pathol 166: 675-684.
    • (2005) Am J Pathol , vol.166 , pp. 675-684
    • Moore, B.B.1    Kolodsick, J.E.2    Thannickal, V.J.3    Cooke, K.4    Moore, T.A.5
  • 51
    • 0032843121 scopus 로고    scopus 로고
    • Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseases
    • Suga M, Iyonaga K, Ichiyasu H, Saita N, Yamasaki H, et al. (1999) Clinical significance of MCP-1 levels in BALF and serum in patients with interstitial lung diseases. Eur Respir J 14: 376-382.
    • (1999) Eur Respir J , vol.14 , pp. 376-382
    • Suga, M.1    Iyonaga, K.2    Ichiyasu, H.3    Saita, N.4    Yamasaki, H.5


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