Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Christian, Michelle L ^a   Demorest, Zachary L ^a   Starker, Colby G ^a   Osborn, Mark J ^a   Nyquist, Michael D ^a   Zhang, Yong ^a   Carlson, Daniel F ^b   Bradley, Philip ^c   Bogdanove, Adam J ^d   Voytas, Daniel F ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c Fred Hutchinson Cancer Research Center   (United States)

^d IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ARGININE NUCLEOTIDE; GUANINE NUCLEOTIDE; NUCLEASE; NUCLEOTIDE; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; TRANSCRIPTION FACTOR; TYROSINE NUCLEOTIDE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA CLEAVAGE; DNA STRUCTURE; ENZYME ACTIVITY; ENZYME SPECIFICITY; FUNGAL GENETICS; GENE CONSTRUCT; GENE TARGETING; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INTERMETHOD COMPARISON; NK REPEAT VARIABLE DI RESIDUE; NN REPEAT VARIABLE DI RESIDUE; NONHUMAN; PROTEIN DNA INTERACTION; PROTEIN ENGINEERING; REPEAT VARIABLE DI RESIDUE; YEAST;

AMINO ACID SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE TARGETING; HUMANS; REPETITIVE SEQUENCES, AMINO ACID; TRANS-ACTIVATORS;

EID: 84866721599     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045383     Document Type: Article

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