In vivo evolution of metabolic pathways by homeologous recombination in mitotic cells

Metabolic Engineering

Volumn 23, Issue , 2014, Pages 123-135

  Luque, Alejandro ^a   Sebai, Sarra C ^a   Santiago Schübel, Beatrix ^b   Le Coz, Yann ^a   Jenot, Delphine ^a   Ramaen, Odile ^a   Sauveplane, Vincent ^a   Pandjaitan, Rudy ^a  

^a EVIAGENICS   (France)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

DNA repair deficiency; Flavonoids; Heterologous expression; Homeologous homologous recombination; In vivo evolution; Metabolic reconstitution; Mosaic pathways; Phenylpropanoids; Yeast

Indexed keywords

GENES; LIBRARIES; METABOLISM; PLANTS (BOTANY); STYRENE; YEAST;

DNA REPAIR; HETEROLOGOUS EXPRESSION; HOMEOLOGOUS/HOMOLOGOUS RECOMBINATION; IN-VIVO; METABOLIC RECONSTITUTION; MOSAIC PATHWAYS; PHENYLPROPANOIDS;

FLAVONOIDS;

CINNAMIC ACID; COUMARIC ACID; DIHYDROKAEMPHEROL 7 GLUCOSIDE; DNA FRAGMENT; FLAVONOID; GALANGIN; GENOMIC DNA; KAEMPFEROL; NARINGENIN; PHLORETIN; PINOCEMBRINE; STYRENE; UNCLASSIFIED DRUG;

ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DNA REPAIR; DNA SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; GEL ELECTROPHORESIS; GENE CLUSTER; GENOME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOLOGOUS RECOMBINATION; IN VIVO STUDY; METABOLITE; MITOSIS; MOSAICISM; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; TANDEM MASS SPECTROMETRY; YEAST CELL; DIRECTED MOLECULAR EVOLUTION; GENETICS; METABOLIC ENGINEERING; METABOLISM; PROCEDURES; SACCHAROMYCES CEREVISIAE;

DIRECTED MOLECULAR EVOLUTION; HOMOLOGOUS RECOMBINATION; METABOLIC ENGINEERING; MITOSIS; SACCHAROMYCES CEREVISIAE;

EID: 84898875126     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2014.02.010     Document Type: Article

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