-
1
-
-
15244340939
-
Altering protein specificity: Techniques and applications
-
Antikainen,N.M. and Martin,S.F. (2005) Altering protein specificity: techniques and applications. Bioorg. Med. Chem., 13, 2701-2716.
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 2701-2716
-
-
Antikainen, N.M.1
Martin, S.F.2
-
2
-
-
18044390504
-
Directed evolution: Selecting today's biocatalysts
-
Otten,L.G. and Quax,W.J. (2005) Directed evolution: Selecting today's biocatalysts. Biomol. Eng., 22, 1-9.
-
(2005)
Biomol. Eng.
, vol.22
, pp. 1-9
-
-
Otten, L.G.1
Quax, W.J.2
-
3
-
-
1842531448
-
Recent progress in biocatalyst discovery and optimization
-
Robertson,D.E. and Steer,B.A. (2004) Recent progress in biocatalyst discovery and optimization. Curr. Opin. Chem. Biol., 8, 141-149.
-
(2004)
Curr. Opin. Chem. Biol.
, vol.8
, pp. 141-149
-
-
Robertson, D.E.1
Steer, B.A.2
-
4
-
-
0035813878
-
Directed evolution and biocatalysis
-
Powell,K.A., Ramer,S.W., del Cardayre,S.B., Stemmer,W.P.C., Tobin,M.B., Longchamp,P.F. and Huisman,G.W. (2001) Directed evolution and biocatalysis. Angew. Chem. Int. Ed. Engl., 40, 3948-3959.
-
(2001)
Angew. Chem. Int. Ed. Engl.
, vol.40
, pp. 3948-3959
-
-
Powell, K.A.1
Ramer, S.W.2
del Cardayre, S.B.3
Stemmer, W.P.C.4
Tobin, M.B.5
Longchamp, P.F.6
Huisman, G.W.7
-
5
-
-
0035804151
-
Discovery of superior enzymes by directed molecular evolution
-
Brakmann,S. (2001) Discovery of superior enzymes by directed molecular evolution. Chembiochem, 2, 865-871.
-
(2001)
Chembiochem
, vol.2
, pp. 865-871
-
-
Brakmann, S.1
-
6
-
-
0035712796
-
Directed enzyme evolution
-
Farinas,E.T., Bulter,T. and Arnold,F.H. (2001) Directed enzyme evolution. Curr. Opin. Biotechnol., 12, 545-551.
-
(2001)
Curr. Opin. Biotechnol.
, vol.12
, pp. 545-551
-
-
Farinas, E.T.1
Bulter, T.2
Arnold, F.H.3
-
7
-
-
2542563521
-
Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: Library construction methods for directed evolution
-
Neylon,C. (2004) Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: Library construction methods for directed evolution. Nucleic Acids Res., 32, 1448-1459.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1448-1459
-
-
Neylon, C.1
-
8
-
-
0002694056
-
A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction
-
Leung,D.W., Chen,E. and Goeddel,D.V. (1989) A method for random mutagenesis of a defined DNA segment using a modified polymerase chain reaction. Technique, 1, 11-15.
-
(1989)
Technique
, vol.1
, pp. 11-15
-
-
Leung, D.W.1
Chen, E.2
Goeddel, D.V.3
-
9
-
-
0029130841
-
The emerging role of insertions and deletions in protein engineering
-
Shortle,D. and Sondek,J. (1995) The emerging role of insertions and deletions in protein engineering. Curr. Opin. Biotechnol., 6, 387-393.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 387-393
-
-
Shortle, D.1
Sondek, J.2
-
10
-
-
0036137462
-
Random insertion and deletion of arbitrary number of bases for codon-based random mutation of DNAs
-
Murakami,H., Hohsaka,T. and Sisido,M. (2002) Random insertion and deletion of arbitrary number of bases for codon-based random mutation of DNAs. Nature Biotechnol., 20, 76-81.
-
(2002)
Nature Biotechnol.
, vol.20
, pp. 76-81
-
-
Murakami, H.1
Hohsaka, T.2
Sisido, M.3
-
11
-
-
0037092188
-
Generating segmental mutations in haloalkane dehalogenase: A novel part in the directed evolution toolbox
-
Pikkemaat,M.G. and Janssen,D.B. (2002) Generating segmental mutations in haloalkane dehalogenase: A novel part in the directed evolution toolbox. Nucleic Acids Res., 30, e35.
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Pikkemaat, M.G.1
Janssen, D.B.2
-
12
-
-
0034548711
-
Pentapeptide scanning mutagenesis: Encouraging old proteins to execute unusual tricks
-
Hayes,F. and Hallet,B. (2000) Pentapeptide scanning mutagenesis: encouraging old proteins to execute unusual tricks. Trends Microbiol., 8, 571-577.
-
(2000)
Trends Microbiol.
, vol.8
, pp. 571-577
-
-
Hayes, F.1
Hallet, B.2
-
13
-
-
23444458590
-
Directed evolution and identification of control regions of ColE1 plasmid replication origins using only nucleotide deletions
-
Kim,D., Rhee,Y., Rhodes,D., Sharma,V., Sorenson,O., Greener,A. and Smider,V. (2005) Directed evolution and identification of control regions of ColE1 plasmid replication origins using only nucleotide deletions. J. Mol. Biol., 351, 763-775.
-
(2005)
J. Mol. Biol.
, vol.351
, pp. 763-775
-
-
Kim, D.1
Rhee, Y.2
Rhodes, D.3
Sharma, V.4
Sorenson, O.5
Greener, A.6
Smider, V.7
-
14
-
-
27244448322
-
Triplet nucleotide removal at random positions in a target gene: The tolerance of TEM-1 β-lactamase to an amino acid deletion
-
Jones,D.D. (2005) Triplet nucleotide removal at random positions in a target gene: The tolerance of TEM-1 β-lactamase to an amino acid deletion. Nucleic Acids Res., 33, e80.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Jones, D.D.1
-
15
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer,W.P.C. (1994) Rapid evolution of a protein in vitro by DNA shuffling. Nature, 370, 389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.C.1
-
16
-
-
0004038637
-
-
Oxford University Press, Oxford
-
Lewin,B. (1994) Genes V. Oxford University Press, Oxford.
-
(1994)
Genes V.
-
-
Lewin, B.1
-
17
-
-
0028048275
-
The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
-
Dixon,F.J. (ed.), Academic Press Inc, San Diego
-
Lewis,S.M. (1994) The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses. In Dixon,F.J. (ed.), Advances in Immunology. Academic Press Inc, San Diego, Vol. 56, pp. 27-150.
-
(1994)
Advances in Immunology
, vol.56
, pp. 27-150
-
-
Lewis, S.M.1
-
18
-
-
0027369562
-
Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes
-
Komori,T., Okada,A., Stewart,V. and Alt,F.W. (1993) Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science, 261, 1171-1175.
-
(1993)
Science
, vol.261
, pp. 1171-1175
-
-
Komori, T.1
Okada, A.2
Stewart, V.3
Alt, F.W.4
-
19
-
-
0034763241
-
Extended-spectrum β-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat
-
Bradford,P.A. (2001) Extended-spectrum β-lactamases in the 21st century: Characterization, epidemiology, and detection of this important resistance threat. Clin. Microbiol. Rev., 14, 933-951.
-
(2001)
Clin. Microbiol. Rev.
, vol.14
, pp. 933-951
-
-
Bradford, P.A.1
-
20
-
-
0028821830
-
Extended-spectrum and inhibitor-resistant TEM-type β-lactamases - Mutations, specificity, and 3-dimensional structure
-
Knox,J.R. (1995) Extended-spectrum and inhibitor-resistant TEM-type β-lactamases - mutations, specificity, and 3-dimensional structure. Antimicrob. Agents Chemother., 39, 2593-2601.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 2593-2601
-
-
Knox, J.R.1
-
21
-
-
0035122917
-
Predicting the emergence of antibiotic resistance by directed evolution and structural analysis
-
Orencia,M.C., Yoon,J.S., Ness,J.E., Stemmer,W.P.C. and Stevens,R.C. (2001) Predicting the emergence of antibiotic resistance by directed evolution and structural analysis. Nature Struct. Biol., 8, 238-242.
-
(2001)
Nature Struct. Biol.
, vol.8
, pp. 238-242
-
-
Orencia, M.C.1
Yoon, J.S.2
Ness, J.E.3
Stemmer, W.P.C.4
Stevens, R.C.5
-
22
-
-
0036193868
-
Predicting evolutionary potential: In vitro evolution accurately reproduces natural evolution of the TEM β-lactamase
-
Barlow,M. and Hall,B.G. (2002) Predicting evolutionary potential: In vitro evolution accurately reproduces natural evolution of the TEM β-lactamase. Genetics, 160, 823-832.
-
(2002)
Genetics
, vol.160
, pp. 823-832
-
-
Barlow, M.1
Hall, B.G.2
-
24
-
-
0028140829
-
Simultaneous mutagenesis of antibody CDR regions by overlap extension and PCR
-
Hayashi,N., Welschof,M., Zewe,M., Braunagel,M., Dubel,S., Breitling,F. and Little,M. (1994) Simultaneous mutagenesis of antibody CDR regions by overlap extension and PCR. Biotechniques, 17, 310-315.
-
(1994)
Biotechniques
, vol.17
, pp. 310-315
-
-
Hayashi, N.1
Welschof, M.2
Zewe, M.3
Braunagel, M.4
Dubel, S.5
Breitling, F.6
Little, M.7
-
25
-
-
0026566796
-
Analysis of insertions/deletions in protein structures
-
Pascarella,S. and Argos,P. (1992) Analysis of insertions/deletions in protein structures. J. Mol. Biol., 224, 461-471.
-
(1992)
J. Mol. Biol.
, vol.224
, pp. 461-471
-
-
Pascarella, S.1
Argos, P.2
-
26
-
-
13844250741
-
High-throughput screens and selections of enzyme-encoding genes
-
Aharoni,A., Griffiths,A.D. and Tawfik,D.S. (2005) High-throughput screens and selections of enzyme-encoding genes. Curr. Opin. Chem. Biol., 9, 210-216.
-
(2005)
Curr. Opin. Chem. Biol.
, vol.9
, pp. 210-216
-
-
Aharoni, A.1
Griffiths, A.D.2
Tawfik, D.S.3
-
28
-
-
3543116602
-
Enzyme assays for high-throughput screening
-
Goddard,J.P. and Reymond,J.L. (2004) Enzyme assays for high-throughput screening. Curr. Opin. Biotechnol., 15, 314-322.
-
(2004)
Curr. Opin. Biotechnol.
, vol.15
, pp. 314-322
-
-
Goddard, J.P.1
Reymond, J.L.2
-
29
-
-
18044397530
-
High-throughput assays for lipases and esterases
-
Schmidt,M. and Bornscheuer,U.T. (2005) High-throughput assays for lipases and esterases. Biomol. Eng., 22, 51-56.
-
(2005)
Biomol. Eng.
, vol.22
, pp. 51-56
-
-
Schmidt, M.1
Bornscheuer, U.T.2
-
30
-
-
0025870126
-
A standard numbering scheme for the class A β-lactamases
-
Ambler,R.P., Coulson,A.F.W., Frere,J.M., Ghuysen,J.M., Joris,B., Forsman,M., Levesque,R.C., Tiraby,G. and Waley,S.G. (1991) A standard numbering scheme for the class A β-lactamases. Biochem. J., 276, 269-270.
-
(1991)
Biochem. J.
, vol.276
, pp. 269-270
-
-
Ambler, R.P.1
Coulson, A.F.W.2
Frere, J.M.3
Ghuysen, J.M.4
Joris, B.5
Forsman, M.6
Levesque, R.C.7
Tiraby, G.8
Waley, S.G.9
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