메뉴 건너뛰기




Volumn 36, Issue 2, 2014, Pages 613-623

Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi

Author keywords

ERK1 2; SIRT1; Streptozotocin; Tau phosphorylation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RESVERATROL; SIRTUIN 1; STREPTOZOCIN; TAU PROTEIN;

EID: 84898873423     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-013-9592-1     Document Type: Article
Times cited : (73)

References (52)
  • 1
    • 79251623365 scopus 로고    scopus 로고
    • Diabetes mellitus and Alzheimer's disease: Shared pathology and treatment?
    • 10.1111/j.1365-2125.2010.03830.x 1:CAS:528:DC%2BC3MXjvFSnurk%3D 21284695 10.1111/j.1365-2125.2010.03830.x 3045545
    • Akter K, Lanza EA, Martin SA, Myronyuk N, Rua M, Raffa RB (2011) Diabetes mellitus and Alzheimer's disease: shared pathology and treatment? Br J Clin Pharmacol 71(3):365-376. doi: 10.1111/j.1365-2125.2010.03830.x
    • (2011) Br J Clin Pharmacol , vol.71 , Issue.3 , pp. 365-376
    • Akter, K.1    Lanza, E.A.2    Martin, S.A.3    Myronyuk, N.4    Rua, M.5    Raffa, R.B.6
  • 2
    • 4043165678 scopus 로고    scopus 로고
    • Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
    • 10.1126/science.1098014 1:CAS:528:DC%2BD2cXmsVGmsbc%3D 15310905 10.1126/science.1098014
    • Araki T, Sasaki Y, Milbrandt J (2004) Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305(5686):1010-1013. doi: 10.1126/science.1098014
    • (2004) Science , vol.305 , Issue.5686 , pp. 1010-1013
    • Araki, T.1    Sasaki, Y.2    Milbrandt, J.3
  • 3
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function
    • 10.1001/archneur.61.5.661 15148141 10.1001/archneur.61.5.661
    • Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA (2004) Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol 61(5):661-666. doi: 10.1001/archneur.61.5.661
    • (2004) Arch Neurol , vol.61 , Issue.5 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 4
    • 33845609090 scopus 로고    scopus 로고
    • Effect of naringenin on intracerebroventricular streptozotocin-induced cognitive deficits in rat: A behavioral analysis
    • 10.1159/000096585 1:CAS:528:DC%2BD28Xht1eqsrvK 17065836 10.1159/000096585
    • Baluchnejadmojarad T, Roghani M (2006) Effect of naringenin on intracerebroventricular streptozotocin-induced cognitive deficits in rat: a behavioral analysis. Pharmacology 78(4):193-197. doi: 10.1159/000096585
    • (2006) Pharmacology , vol.78 , Issue.4 , pp. 193-197
    • Baluchnejadmojarad, T.1    Roghani, M.2
  • 5
    • 52749091816 scopus 로고    scopus 로고
    • SirT1 gain of function increases energy efficiency and prevents diabetes in mice
    • 10.1016/j.cmet.2008.08.014 1:CAS:528:DC%2BD1cXht1Cit77L 18840364 10.1016/j.cmet.2008.08.014 3222897
    • Banks AS, Kon N, Knight C, Matsumoto M, Gutierrez-Juarez R, Rossetti L, Gu W, Accili D (2008) SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 8(4):333-341. doi: 10.1016/j.cmet.2008.08. 014
    • (2008) Cell Metab , vol.8 , Issue.4 , pp. 333-341
    • Banks, A.S.1    Kon, N.2    Knight, C.3    Matsumoto, M.4    Gutierrez-Juarez, R.5    Rossetti, L.6    Gu, W.7    Accili, D.8
  • 6
    • 0029821906 scopus 로고    scopus 로고
    • Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats
    • 1:CAS:528:DyaK28XlsFemtLk%3D 8772732 10.2337/diab.45.9.1259
    • Biessels GJ, Kamal A, Ramakers GM, Urban IJ, Spruijt BM, Erkelens DW, Gispen WH (1996a) Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. Diabetes 45(9):1259-1266
    • (1996) Diabetes , vol.45 , Issue.9 , pp. 1259-1266
    • Biessels, G.J.1    Kamal, A.2    Ramakers, G.M.3    Urban, I.J.4    Spruijt, B.M.5    Erkelens, D.W.6    Gispen, W.H.7
  • 7
    • 0012702580 scopus 로고    scopus 로고
    • Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes
    • 1:CAS:528:DyaK28XlslKktro%3D 8866422 10.1016/0022-510X(96)00080-9
    • Biessels GJ, Stevens EJ, Mahmood SJ, Gispen WH, Tomlinson DR (1996b) Insulin partially reverses deficits in peripheral nerve blood flow and conduction in experimental diabetes. J Neurol Sci 140(1-2):12-20
    • (1996) J Neurol Sci , vol.140 , Issue.1-2 , pp. 12-20
    • Biessels, G.J.1    Stevens, E.J.2    Mahmood, S.J.3    Gispen, W.H.4    Tomlinson, D.R.5
  • 8
    • 84859429591 scopus 로고    scopus 로고
    • Sirtuins in cognitive ageing and Alzheimer's disease
    • 10.1097/YCO.0b013e32835112c1 22327552 10.1097/YCO.0b013e32835112c1
    • Braidy N, Jayasena T, Poljak A, Sachdev PS (2012) Sirtuins in cognitive ageing and Alzheimer's disease. Curr Opin Psychiatry 25(3):226-230. doi: 10.1097/YCO.0b013e32835112c1
    • (2012) Curr Opin Psychiatry , vol.25 , Issue.3 , pp. 226-230
    • Braidy, N.1    Jayasena, T.2    Poljak, A.3    Sachdev, P.S.4
  • 9
    • 0036255284 scopus 로고    scopus 로고
    • Low-dose radiation hypersensitivity in human tumor cell lines: Effects of cell-cell contact and nutritional deprivation
    • 1:CAS:528:DC%2BD38XjsFamtbw%3D 11966317 10.1667/0033-7587(2002)157[0516: LDRHIH]2.0.CO;2
    • Chandna S, Dwarakanath BS, Khaitan D, Mathew TL, Jain V (2002) Low-dose radiation hypersensitivity in human tumor cell lines: effects of cell-cell contact and nutritional deprivation. Radiat Res 157(5):516-525
    • (2002) Radiat Res , vol.157 , Issue.5 , pp. 516-525
    • Chandna, S.1    Dwarakanath, B.S.2    Khaitan, D.3    Mathew, T.L.4    Jain, V.5
  • 10
    • 34548055825 scopus 로고    scopus 로고
    • Expressions of Abeta1-40, Abeta1-42, tau202, tau396 and tau404 after intracerebroventricular injection of streptozotocin in rats
    • 1:CAS:528:DC%2BD2MXis1Cgtbk%3D 173
    • Chu WZ, Qian CY (2005) Expressions of Abeta1-40, Abeta1-42, tau202, tau396 and tau404 after intracerebroventricular injection of streptozotocin in rats. Acad J First Med Coll PLA (Di 1 jun yi da xue xue bao) 25(2):168-170, 173
    • (2005) Acad J First Med Coll PLA (Di 1 Jun Yi da Xue Xue Bao) , vol.25 , Issue.2 , pp. 168-170
    • Chu, W.Z.1    Qian, C.Y.2
  • 11
    • 79953087890 scopus 로고    scopus 로고
    • The acetylation of tau inhibits its function and promotes pathological tau aggregation
    • 10.1038/ncomms1255 21427723 10.1038/ncomms1255 3120096
    • Cohen TJ, Guo JL, Hurtado DE, Kwong LK, Mills IP, Trojanowski JQ, Lee VM (2011) The acetylation of tau inhibits its function and promotes pathological tau aggregation. Nat Commun 2:252. doi: 10.1038/ncomms1255
    • (2011) Nat Commun , vol.2 , pp. 252
    • Cohen, T.J.1    Guo, J.L.2    Hurtado, D.E.3    Kwong, L.K.4    Mills, I.P.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 12
    • 73649112749 scopus 로고    scopus 로고
    • Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease
    • 10.2353/ajpath.2009.090157 1:CAS:528:DC%2BC3cXhslSjtb0%3D 19815707 10.2353/ajpath.2009.090157 2774072
    • Deng Y, Li B, Liu Y, Iqbal K, Grundke-Iqbal I, Gong CX (2009) Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: implication for Alzheimer's disease. Am J Pathol 175(5):2089-2098. doi: 10.2353/ajpath.2009. 090157
    • (2009) Am J Pathol , vol.175 , Issue.5 , pp. 2089-2098
    • Deng, Y.1    Li, B.2    Liu, Y.3    Iqbal, K.4    Grundke-Iqbal, I.5    Gong, C.X.6
  • 13
    • 77955046461 scopus 로고    scopus 로고
    • SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
    • 10.1016/j.cell.2010.06.020 1:CAS:528:DC%2BC3cXpsVahsrw%3D 20655472 10.1016/j.cell.2010.06.020 2911635
    • Donmez G, Wang D, Cohen DE, Guarente L (2010) SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142(2):320-332. doi: 10.1016/j.cell.2010.06.020
    • (2010) Cell , vol.142 , Issue.2 , pp. 320-332
    • Donmez, G.1    Wang, D.2    Cohen, D.E.3    Guarente, L.4
  • 14
    • 28444485025 scopus 로고    scopus 로고
    • Experimental treatment for focal hyperglycemic ischemic brain injury in the rat
    • 10.1007/s00221-005-0157-0 1:CAS:528:DC%2BD2MXht1OqsLvK 16261339 10.1007/s00221-005-0157-0
    • Farrokhnia N, Roos MW, Terent A, Lennmyr F (2005) Experimental treatment for focal hyperglycemic ischemic brain injury in the rat. Exp Brain Res 167(2):310-314. doi: 10.1007/s00221-005-0157-0
    • (2005) Exp Brain Res , vol.167 , Issue.2 , pp. 310-314
    • Farrokhnia, N.1    Roos, M.W.2    Terent, A.3    Lennmyr, F.4
  • 15
    • 0030992061 scopus 로고    scopus 로고
    • Binding properties of glutamate receptors in streptozotocin-induced diabetes in rats
    • 1:CAS:528:DyaK2sXjtVGntLc%3D 9133553 10.2337/diabetes.46.5.841
    • Gagne J, Milot M, Gelinas S, Lahsaini A, Trudeau F, Martinoli MG, Massicotte G (1997) Binding properties of glutamate receptors in streptozotocin-induced diabetes in rats. Diabetes 46(5):841-846
    • (1997) Diabetes , vol.46 , Issue.5 , pp. 841-846
    • Gagne, J.1    Milot, M.2    Gelinas, S.3    Lahsaini, A.4    Trudeau, F.5    Martinoli, M.G.6    Massicotte, G.7
  • 16
  • 17
    • 78650987216 scopus 로고    scopus 로고
    • Sirtuin-1 regulation of mammalian metabolism
    • 10.1016/j.molmed.2010.09.005
    • Gillum MP, Erion DM, Shulman GI (2010) Sirtuin-1 regulation of mammalian metabolism. Trends Mol Med 17(1):8-13. doi: 10.1016/j.molmed.2010.09.005
    • (2010) Trends Mol Med , vol.17 , Issue.1 , pp. 8-13
    • Gillum, M.P.1    Erion, D.M.2    Shulman, G.I.3
  • 18
    • 34247324303 scopus 로고    scopus 로고
    • Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
    • 10.1111/j.1471-4159.2006.04368.x 17448147 10.1111/j.1471-4159.2006.04368. x
    • Grunblatt E, Salkovic-Petrisic M, Osmanovic J, Riederer P, Hoyer S (2007) Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein. J Neurochem 101(3):757-770. doi: 10.1111/j.1471-4159.2006.04368.x
    • (2007) J Neurochem , vol.101 , Issue.3 , pp. 757-770
    • Grunblatt, E.1    Salkovic-Petrisic, M.2    Osmanovic, J.3    Riederer, P.4    Hoyer, S.5
  • 19
    • 13844262643 scopus 로고    scopus 로고
    • The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways
    • 10.1016/j.brainres.2004.11.050 1:CAS:528:DC%2BD2MXhtlSmu78%3D 15713276 10.1016/j.brainres.2004.11.050
    • Guan QH, Pei DS, Zhang QG, Hao ZB, Xu TL, Zhang GY (2005) The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways. Brain Res 1035(1):51-59. doi: 10.1016/j.brainres.2004. 11.050
    • (2005) Brain Res , vol.1035 , Issue.1 , pp. 51-59
    • Guan, Q.H.1    Pei, D.S.2    Zhang, Q.G.3    Hao, Z.B.4    Xu, T.L.5    Zhang, G.Y.6
  • 20
    • 4944235387 scopus 로고    scopus 로고
    • Effects of hyperglycemic and normoglycemic cerebral ischemia on phosphorylation of c-jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK)
    • 1:CAS:528:DC%2BD2cXhslSisLg%3D
    • He QP, Ding C, Li PA (2003) Effects of hyperglycemic and normoglycemic cerebral ischemia on phosphorylation of c-jun NH2-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK). Cell Mol Biol (Noisy-le-grand) 49(8):1241-1247
    • (2003) Cell Mol Biol (Noisy-le-grand) , vol.49 , Issue.8 , pp. 1241-1247
    • He, Q.P.1    Ding, C.2    Li, P.A.3
  • 21
    • 50649105709 scopus 로고    scopus 로고
    • Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: Comparison to intracerebroventricular streptozotocin
    • 10.1007/s00702-008-0079-7 1:CAS:528:DC%2BD1cXhtVektb%2FM 18679562 10.1007/s00702-008-0079-7
    • Hoyer S, Lannert H (2008) Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin. J Neural Transm 115(9):1241-1249. doi: 10.1007/s00702-008-0079-7
    • (2008) J Neural Transm , vol.115 , Issue.9 , pp. 1241-1249
    • Hoyer, S.1    Lannert, H.2
  • 22
    • 0034537362 scopus 로고    scopus 로고
    • Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease?
    • 1:CAS:528:DC%2BD3MXotlaitQ%3D%3D 11193160 10.1111/j.1749-6632.2000. tb06932.x
    • Hoyer S, Lee SK, Loffler T, Schliebs R (2000) Inhibition of the neuronal insulin receptor. An in vivo model for sporadic Alzheimer disease? Ann N Y Acad Sci 920:256-258
    • (2000) Ann N y Acad Sci , vol.920 , pp. 256-258
    • Hoyer, S.1    Lee, S.K.2    Loffler, T.3    Schliebs, R.4
  • 23
    • 0024545260 scopus 로고
    • Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type
    • 1:STN:280:DyaL1M7nslSrsw%3D%3D 2926384 10.1007/BF01258634
    • Hoyer S, Nitsch R (1989) Cerebral excess release of neurotransmitter amino acids subsequent to reduced cerebral glucose metabolism in early-onset dementia of Alzheimer type. J Neural Transm 75(3):227-232
    • (1989) J Neural Transm , vol.75 , Issue.3 , pp. 227-232
    • Hoyer, S.1    Nitsch, R.2
  • 24
    • 64049092736 scopus 로고    scopus 로고
    • Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease
    • 10.1097/NEN.0b013e3181922348 1:CAS:528:DC%2BD1MXhsFGlsrg%3D 19104446 10.1097/NEN.0b013e3181922348 2813570
    • Julien C, Tremblay C, Emond V, Lebbadi M, Salem N Jr, Bennett DA, Calon F (2009) Sirtuin 1 reduction parallels the accumulation of tau in Alzheimer disease. J Neuropathol Exp Neurol 68(1):48-58. doi: 10.1097/NEN.0b013e3181922348
    • (2009) J Neuropathol Exp Neurol , vol.68 , Issue.1 , pp. 48-58
    • Julien, C.1    Tremblay, C.2    Emond, V.3    Lebbadi, M.4    Salem, Jr.N.5    Bennett, D.A.6    Calon, F.7
  • 25
    • 33644941776 scopus 로고    scopus 로고
    • Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats
    • 10.1016/j.brainres.2005.12.070 16455062 10.1016/j.brainres.2005.12.070
    • Kamal A, Biessels GJ, Gispen WH, Ramakers GM (2006) Synaptic transmission changes in the pyramidal cells of the hippocampus in streptozotocin-induced diabetes mellitus in rats. Brain Res 1073-1074:276-280. doi: 10.1016/j.brainres.2005.12.070
    • (2006) Brain Res , vol.1073-1074 , pp. 276-280
    • Kamal, A.1    Biessels, G.J.2    Gispen, W.H.3    Ramakers, G.M.4
  • 27
    • 0348112441 scopus 로고    scopus 로고
    • Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex
    • 1:CAS:528:DC%2BD3sXps1Gkt7o%3D 14672811 10.1016/j.brainres.2003.10.005
    • Kurihara J, Katsura K, Siesjo BK, Wieloch T (2004) Hyperglycemia and hypercapnia differently affect post-ischemic changes in protein kinases and protein phosphorylation in the rat cingulate cortex. Brain Res 995(2):218-225
    • (2004) Brain Res , vol.995 , Issue.2 , pp. 218-225
    • Kurihara, J.1    Katsura, K.2    Siesjo, B.K.3    Wieloch, T.4
  • 28
    • 0035112956 scopus 로고    scopus 로고
    • Phosphorylation of extracellular signal-regulated kinase after transient cerebral ischemia in hyperglycemic rats
    • 10.1006/nbdi.2000.0363 1:CAS:528:DC%2BD3MXpvVSqsg%3D%3D 11162246 10.1006/nbdi.2000.0363
    • Li PA, He QP, Yi-Bing O, Hu BR, Siesjo BK (2001) Phosphorylation of extracellular signal-regulated kinase after transient cerebral ischemia in hyperglycemic rats. Neurobiol Dis 8(1):127-135. doi: 10.1006/nbdi.2000.0363
    • (2001) Neurobiol Dis , vol.8 , Issue.1 , pp. 127-135
    • Li, P.A.1    He, Q.P.2    Yi-Bing, O.3    Hu, B.R.4    Siesjo, B.K.5
  • 29
    • 34347377319 scopus 로고    scopus 로고
    • Alzheimer-like changes in rat models of spontaneous diabetes
    • 10.2337/db07-0171 1:CAS:528:DC%2BD2sXnvVWju70%3D 17456849 10.2337/db07-0171
    • Li ZG, Zhang W, Sima AA (2007) Alzheimer-like changes in rat models of spontaneous diabetes. Diabetes 56(7):1817-1824. doi: 10.2337/db07-0171
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1817-1824
    • Li, Z.G.1    Zhang, W.2    Sima, A.A.3
  • 30
    • 42949083261 scopus 로고    scopus 로고
    • Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye
    • 1:CAS:528:DC%2BD1cXmtFWrt7c%3D 18432318 2324119
    • Liu WB, Li Y, Zhang L, Chen HG, Sun S, Liu JP, Liu Y, Li DW (2008) Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye. Mol Vis 14:762-773
    • (2008) Mol Vis , vol.14 , pp. 762-773
    • Liu, W.B.1    Li, Y.2    Zhang, L.3    Chen, H.G.4    Sun, S.5    Liu, J.P.6    Liu, Y.7    Li, D.W.8
  • 31
    • 79960896430 scopus 로고    scopus 로고
    • Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes
    • 10.1002/path.2912 1:CAS:528:DC%2BC3MXpt1Cns78%3D 21598254 10.1002/path.2912
    • Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2011) Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. J Pathol 225(1):54-62. doi: 10.1002/path.2912
    • (2011) J Pathol , vol.225 , Issue.1 , pp. 54-62
    • Liu, Y.1    Liu, F.2    Grundke-Iqbal, I.3    Iqbal, K.4    Gong, C.X.5
  • 34
    • 0035949472 scopus 로고    scopus 로고
    • Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia
    • 10.1073/pnas.181213498 1:CAS:528:DC%2BD3MXnt12js74%3D 11504919 10.1073/pnas.181213498 58770
    • Namura S, Iihara K, Takami S, Nagata I, Kikuchi H, Matsushita K, Moskowitz MA, Bonventre JV, Alessandrini A (2001) Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia. Proc Natl Acad Sci U S A 98(20):11569-11574. doi: 10.1073/pnas.181213498
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.20 , pp. 11569-11574
    • Namura, S.1    Iihara, K.2    Takami, S.3    Nagata, I.4    Kikuchi, H.5    Matsushita, K.6    Moskowitz, M.A.7    Bonventre, J.V.8    Alessandrini, A.9
  • 35
    • 12244279939 scopus 로고    scopus 로고
    • Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease
    • 1:CAS:528:DC%2BD3sXivVChsw%3D%3D 12531514 10.1016/S0169-328X(02)00488-6
    • Pei JJ, Braak H, An WL, Winblad B, Cowburn RF, Iqbal K, Grundke-Iqbal I (2002) Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Res Mol Brain Res 109(1-2):45-55
    • (2002) Brain Res Mol Brain Res , vol.109 , Issue.1-2 , pp. 45-55
    • Pei, J.J.1    Braak, H.2    An, W.L.3    Winblad, B.4    Cowburn, R.F.5    Iqbal, K.6    Grundke-Iqbal, I.7
  • 36
    • 0042679509 scopus 로고    scopus 로고
    • Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease
    • 10.1016/S0002-9440(10)63445-1 1:CAS:528:DC%2BD3sXnsVCjur0%3D 12937126 10.1016/S0002-9440(10)63445-1 1868262
    • Pei JJ, Gong CX, An WL, Winblad B, Cowburn RF, Grundke-Iqbal I, Iqbal K (2003) Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. Am J Pathol 163(3):845-858. doi: 10.1016/S0002-9440(10)63445-1
    • (2003) Am J Pathol , vol.163 , Issue.3 , pp. 845-858
    • Pei, J.J.1    Gong, C.X.2    An, W.L.3    Winblad, B.4    Cowburn, R.F.5    Grundke-Iqbal, I.6    Iqbal, K.7
  • 37
    • 77049100748 scopus 로고    scopus 로고
    • Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice
    • 10.3233/JAD-2010-1270 1:CAS:528:DC%2BC3cXht1SltL4%3D 20110613
    • Plaschke K, Kopitz J, Siegelin M, Schliebs R, Salkovic-Petrisic M, Riederer P, Hoyer S (2010) Insulin-resistant brain state after intracerebroventricular streptozotocin injection exacerbates Alzheimer-like changes in Tg2576 AbetaPP-overexpressing mice. J Alzheimers Dis 19(2):691-704. doi: 10.3233/JAD-2010-1270
    • (2010) J Alzheimers Dis , vol.19 , Issue.2 , pp. 691-704
    • Plaschke, K.1    Kopitz, J.2    Siegelin, M.3    Schliebs, R.4    Salkovic-Petrisic, M.5    Riederer, P.6    Hoyer, S.7
  • 38
    • 84863012694 scopus 로고    scopus 로고
    • Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding
    • 10.1096/fj.11-195172 1:CAS:528:DC%2BC38XitFOnsL8%3D 22006157 10.1096/fj.11-195172 3290439
    • Purushotham A, Xu Q, Li X (2012) Systemic SIRT1 insufficiency results in disruption of energy homeostasis and steroid hormone metabolism upon high-fat-diet feeding. FASEB J 26(2):656-667. doi: 10.1096/fj.11-195172
    • (2012) FASEB J , vol.26 , Issue.2 , pp. 656-667
    • Purushotham, A.1    Xu, Q.2    Li, X.3
  • 41
    • 14544282413 scopus 로고    scopus 로고
    • Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
    • 10.1038/nature03354 1:CAS:528:DC%2BD2MXhslClsb0%3D 15744310 10.1038/nature03354
    • Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P (2005) Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434(7029):113-118. doi: 10.1038/nature03354
    • (2005) Nature , vol.434 , Issue.7029 , pp. 113-118
    • Rodgers, J.T.1    Lerin, C.2    Haas, W.3    Gygi, S.P.4    Spiegelman, B.M.5    Puigserver, P.6
  • 42
    • 84862294189 scopus 로고    scopus 로고
    • ERK1/2 MAP kinases: Structure, function, and regulation
    • 10.1016/j.phrs.2012.04.005 1:CAS:528:DC%2BC38XovVygs7k%3D
    • Roskoski R Jr (2012) ERK1/2 MAP kinases: structure, function, and regulation. Pharmacol Res Off J Ital Pharmacol Soc 66(2):105-143. doi: 10.1016/j.phrs.2012.04.005
    • (2012) Pharmacol Res off J Ital Pharmacol Soc , vol.66 , Issue.2 , pp. 105-143
    • Roskoski, Jr.R.1
  • 43
    • 38449088511 scopus 로고    scopus 로고
    • Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: An experimental approach
    • 1:CAS:528:DC%2BD2sXhsVKns7bN 17982898 10.1007/978-3-211-73574-9-28
    • Salkovic-Petrisic M, Hoyer S (2007) Central insulin resistance as a trigger for sporadic Alzheimer-like pathology: an experimental approach. J Neural Transm Suppl 72:217-233
    • (2007) J Neural Transm Suppl , vol.72 , pp. 217-233
    • Salkovic-Petrisic, M.1    Hoyer, S.2
  • 44
    • 33645100144 scopus 로고    scopus 로고
    • Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway
    • 10.1111/j.1471-4159.2005.03637.x 1:CAS:528:DC%2BD28XivFWjsr8%3D 16412093 10.1111/j.1471-4159.2005.03637.x
    • Salkovic-Petrisic M, Tribl F, Schmidt M, Hoyer S, Riederer P (2006) Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway. J Neurochem 96(4):1005-1015. doi: 10.1111/j.1471-4159.2005.03637.x
    • (2006) J Neurochem , vol.96 , Issue.4 , pp. 1005-1015
    • Salkovic-Petrisic, M.1    Tribl, F.2    Schmidt, M.3    Hoyer, S.4    Riederer, P.5
  • 45
    • 84858214548 scopus 로고    scopus 로고
    • Diabetes mellitus as a modulator of functional impairment and decline in Alzheimer's disease. The Real.FR cohort
    • 10.1111/j.1464-5491.2011.03445.x 1:STN:280:DC%2BC38zgtlCgtw%3D%3D 21913970 10.1111/j.1464-5491.2011.03445.x
    • Sanz CM, Hanaire H, Vellas BJ, Sinclair AJ, Andrieu S, Group RFS (2012) Diabetes mellitus as a modulator of functional impairment and decline in Alzheimer's disease. The Real.FR cohort. Diabet Med 29(4):541-548. doi: 10.1111/j.1464-5491.2011.03445.x
    • (2012) Diabet Med , vol.29 , Issue.4 , pp. 541-548
    • Sanz, C.M.1    Hanaire, H.2    Vellas, B.J.3    Sinclair, A.J.4    Andrieu, S.5    Group, R.F.S.6
  • 47
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - Is this type 3 diabetes?
    • 1:CAS:528:DC%2BD2MXhvVSrtL8%3D 15750215
    • Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM (2005) Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes? J Alzheimers Dis 7(1):63-80
    • (2005) J Alzheimers Dis , vol.7 , Issue.1 , pp. 63-80
    • Steen, E.1    Terry, B.M.2    Rivera, E.J.3    Cannon, J.L.4    Neely, T.R.5    Tavares, R.6    Xu, X.J.7    Wands, J.R.8    De La Monte, S.M.9
  • 48
    • 0032707190 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, cognitive impairment and dementia
    • 1:STN:280:DyaK1M3ksVejug%3D%3D 10229302 10.1046/j.1464-5491.1999.00027.x
    • Stewart R, Liolitsa D (1999) Type 2 diabetes mellitus, cognitive impairment and dementia. Diabet Med 16(2):93-112
    • (1999) Diabet Med , vol.16 , Issue.2 , pp. 93-112
    • Stewart, R.1    Liolitsa, D.2
  • 49
    • 73249130996 scopus 로고    scopus 로고
    • High glucose induces transactivation of the alpha2-HS glycoprotein gene through the ERK1/2 signaling pathway
    • 1:CAS:528:DC%2BD1MXht1antrjP 19672022 10.5551/jat.No950
    • Takata H, Ikeda Y, Suehiro T, Ishibashi A, Inoue M, Kumon Y, Terada Y (2009) High glucose induces transactivation of the alpha2-HS glycoprotein gene through the ERK1/2 signaling pathway. J Atheroscler Thromb 16(4):448-456
    • (2009) J Atheroscler Thromb , vol.16 , Issue.4 , pp. 448-456
    • Takata, H.1    Ikeda, Y.2    Suehiro, T.3    Ishibashi, A.4    Inoue, M.5    Kumon, Y.6    Terada, Y.7
  • 50
    • 0021001470 scopus 로고
    • Distribution and metabolism in Syrian golden hamsters of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen
    • 1:STN:280:DyaL2c3jsFKjsQ%3D%3D 6677480
    • Tjalve H, Castonguay A (1983) Distribution and metabolism in Syrian golden hamsters of 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen. Dev Toxicol Environ Sci 11:423-427
    • (1983) Dev Toxicol Environ Sci , vol.11 , pp. 423-427
    • Tjalve, H.1    Castonguay, A.2
  • 51
    • 7044270594 scopus 로고    scopus 로고
    • Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses
    • 10.1002/bit.20235 1:CAS:528:DC%2BD2cXot1Kju7c%3D 15449293 10.1002/bit.20235
    • Visser D, van Zuylen GA, van Dam JC, Eman MR, Proll A, Ras C, Wu L, van Gulik WM, Heijnen JJ (2004) Analysis of in vivo kinetics of glycolysis in aerobic Saccharomyces cerevisiae by application of glucose and ethanol pulses. Biotechnol Bioeng 88(2):157-167. doi: 10.1002/bit.20235
    • (2004) Biotechnol Bioeng , vol.88 , Issue.2 , pp. 157-167
    • Visser, D.1    Van Zuylen, G.A.2    Van Dam, J.C.3    Eman, M.R.4    Proll, A.5    Ras, C.6    Wu, L.7    Van Gulik, W.M.8    Heijnen, J.J.9
  • 52
    • 30944439466 scopus 로고    scopus 로고
    • Hyperglycemia increased brain ischemia injury through extracellular signal-regulated protein Kinase
    • 10.1016/j.prp.2005.10.002 1:CAS:528:DC%2BD28XhsFyntLg%3D 16343798 10.1016/j.prp.2005.10.002
    • Zhang JZ, Jing L, Ma AL, Wang F, Yu X, Wang YL (2006) Hyperglycemia increased brain ischemia injury through extracellular signal-regulated protein Kinase. Pathol Res Pract 202(1):31-36. doi: 10.1016/j.prp.2005.10.002
    • (2006) Pathol Res Pract , vol.202 , Issue.1 , pp. 31-36
    • Zhang, J.Z.1    Jing, L.2    Ma, A.L.3    Wang, F.4    Yu, X.5    Wang, Y.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.