Excretion of [3H]triptolide and its metabolites in rats after oral administration

Acta Pharmacologica Sinica

Volumn 35, Issue 4, 2014, Pages 549-554

  Liu, Jia ^a   Zhou, Xin ^a   Chen, Xiao Yan ^a   Zhong, Da Fang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Excretion pathway; Gender difference; Immunosuppressant; Pharmacokinetics; Triptolide

Indexed keywords

DRUG METABOLITE; SULFOTRANSFERASE; TRIPTOLIDE; TRITIUM; DITERPENE; EPOXIDE; PHENANTHRENE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BILIARY EXCRETION; DRUG ELIMINATION; DRUG EXCRETION; DRUG FECES LEVEL; DRUG URINE LEVEL; FEMALE; ISOTOPE LABELING; MALE; NONHUMAN; PROTEIN EXPRESSION; RADIOACTIVITY; RAT; SEX DIFFERENCE; SPRAGUE DAWLEY RAT; ANIMAL; BILE; BIOTRANSFORMATION; CHEMISTRY; FECES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; ORAL DRUG ADMINISTRATION; SCINTILLATION COUNTING; URINARY EXCRETION; URINE;

ADMINISTRATION, ORAL; ANIMALS; BILE; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES; EPOXY COMPOUNDS; FECES; FEMALE; HEPATOBILIARY ELIMINATION; MALE; PHENANTHRENES; RATS, SPRAGUE-DAWLEY; RENAL ELIMINATION; SCINTILLATION COUNTING; SEX FACTORS; TRITIUM;

EID: 84898716031     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.192     Document Type: Article

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