메뉴 건너뛰기




Volumn 125, Issue 1, 2009, Pages 41-46

Triptolide promotes generation of FoxP3+ T regulatory cells in rats

Author keywords

CD4+ cells; FoxP3 expression; Kidney transplantation; T regulatory cells; Triptolide

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CYCLOSPORIN A; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TRIPTOLIDE;

EID: 67651083724     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.06.020     Document Type: Article
Times cited : (19)

References (23)
  • 1
    • 20444373376 scopus 로고    scopus 로고
    • Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
    • Battaglia M., Stabilini A., and Roncarolo M.G. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 105 (2005) 4743-4748
    • (2005) Blood , vol.105 , pp. 4743-4748
    • Battaglia, M.1    Stabilini, A.2    Roncarolo, M.G.3
  • 2
    • 34547769253 scopus 로고    scopus 로고
    • All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
    • Benson M.J., Pino-Lagos K., Rosemblatt M., and Noelle R.J. All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. The Journal of Experimental Medicine 204 (2007) 1765-1774
    • (2007) The Journal of Experimental Medicine , vol.204 , pp. 1765-1774
    • Benson, M.J.1    Pino-Lagos, K.2    Rosemblatt, M.3    Noelle, R.J.4
  • 3
    • 0034909663 scopus 로고    scopus 로고
    • Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F. Leuk Lymphoma
    • Chen B.J. Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F. Leuk Lymphoma. Leukemia and Lymphoma 42 (2001) 253-265
    • (2001) Leukemia and Lymphoma , vol.42 , pp. 253-265
    • Chen, B.J.1
  • 4
    • 0037080958 scopus 로고    scopus 로고
    • Mechanisms of tolerance induced by PG490-88 in a bone marrow transplantation model
    • Chen B.J., Chen Y., Cui X., Fidler J.M., and Chao N.J. Mechanisms of tolerance induced by PG490-88 in a bone marrow transplantation model. Transplantation 73 (2002) 115-121
    • (2002) Transplantation , vol.73 , pp. 115-121
    • Chen, B.J.1    Chen, Y.2    Cui, X.3    Fidler, J.M.4    Chao, N.J.5
  • 5
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • Chen W., Jin W., Hardegen N., Lei K.J., Li L., Marinos N., McGrady G., and Wahl S.M. Conversion of peripheral CD4+CD25-naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. The Journal of Experimental Medicine 198 (2003) 1875-1886
    • (2003) The Journal of Experimental Medicine , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 6
    • 27144467100 scopus 로고    scopus 로고
    • Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking
    • Chen X., Murakami T., Oppenheim J.J., and Howard O.M. Triptolide, a constituent of immunosuppressive Chinese herbal medicine, is a potent suppressor of dendritic-cell maturation and trafficking. Blood 106 (2005) 2409-2416
    • (2005) Blood , vol.106 , pp. 2409-2416
    • Chen, X.1    Murakami, T.2    Oppenheim, J.J.3    Howard, O.M.4
  • 7
    • 41149178744 scopus 로고    scopus 로고
    • Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting?
    • Demirkiran A., Hendrikx T.K., Baan C.C., and van der Laan L.J. Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting?. Transplantation 85 (2008) 783-789
    • (2008) Transplantation , vol.85 , pp. 783-789
    • Demirkiran, A.1    Hendrikx, T.K.2    Baan, C.C.3    van der Laan, L.J.4
  • 8
    • 0042318615 scopus 로고    scopus 로고
    • Analysis of triptolide-regulated gene expression in Jurkat cells by complementary DNA microarray
    • Du Z.Y., Li X.Y., Li Y.C., and Wang S.Y. Analysis of triptolide-regulated gene expression in Jurkat cells by complementary DNA microarray. Acta Pharmacologica Sinica 24 (2003) 864-872
    • (2003) Acta Pharmacologica Sinica , vol.24 , pp. 864-872
    • Du, Z.Y.1    Li, X.Y.2    Li, Y.C.3    Wang, S.Y.4
  • 9
    • 34250156673 scopus 로고    scopus 로고
    • Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells
    • Gao W., Lu Y., El Essawy B., Oukka M., Kuchroo V.K., and Strom T.B. Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. American Journal of Transplantation 7 (2007) 1722-1732
    • (2007) American Journal of Transplantation , vol.7 , pp. 1722-1732
    • Gao, W.1    Lu, Y.2    El Essawy, B.3    Oukka, M.4    Kuchroo, V.K.5    Strom, T.B.6
  • 10
    • 0032891801 scopus 로고    scopus 로고
    • Mechanism of immunosuppression of the antirheumatic herb TWHf in human T cells
    • Ho L.J., Chang D.M., Chang M.L., Kuo S.Y., and Lai J.H. Mechanism of immunosuppression of the antirheumatic herb TWHf in human T cells. The Journal of Rheumatology 26 (1999) 14-24
    • (1999) The Journal of Rheumatology , vol.26 , pp. 14-24
    • Ho, L.J.1    Chang, D.M.2    Chang, M.L.3    Kuo, S.Y.4    Lai, J.H.5
  • 11
    • 34248679904 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects
    • Kang S.M., Tang Q., and Bluestone J.A. CD4+CD25+ regulatory T cells in transplantation: progress, challenges and prospects. American Journal of Transplantation 7 (2007) 1457-1463
    • (2007) American Journal of Transplantation , vol.7 , pp. 1457-1463
    • Kang, S.M.1    Tang, Q.2    Bluestone, J.A.3
  • 13
    • 41749112206 scopus 로고    scopus 로고
    • Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation
    • Liu Y., Chen Y., Liu F.Q., Lamb J.R., and Tam P.K. Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation. Transplant International 21 (2008) 483-494
    • (2008) Transplant International , vol.21 , pp. 483-494
    • Liu, Y.1    Chen, Y.2    Liu, F.Q.3    Lamb, J.R.4    Tam, P.K.5
  • 16
    • 0042662901 scopus 로고    scopus 로고
    • Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f. Drugs R D
    • Qiu D., and Kao P.N. Immunosuppressive and anti-inflammatory mechanisms of triptolide, the principal active diterpenoid from the Chinese medicinal herb Tripterygium wilfordii Hook. f. Drugs R D. Drugs in R&D 4 (2003) 1-18
    • (2003) Drugs in R&D , vol.4 , pp. 1-18
    • Qiu, D.1    Kao, P.N.2
  • 18
    • 0041331504 scopus 로고    scopus 로고
    • Kidney transplantation in rats: an appraisal of surgical techniques and outcome
    • Schumacher M., Van Vliet B.N., and Ferrari P. Kidney transplantation in rats: an appraisal of surgical techniques and outcome. Microsurgery 23 (2003) 387-394
    • (2003) Microsurgery , vol.23 , pp. 387-394
    • Schumacher, M.1    Van Vliet, B.N.2    Ferrari, P.3
  • 21
    • 27744515382 scopus 로고    scopus 로고
    • Prevention of graft-versus-host disease by a novel immunosuppressant, (5R)-5-hydroxytriptolide (LLDT-8), through expansion of regulatory T cells
    • Tang W., Yang Y., Zhang F., Li Y.C., Zhou R., Wang J.X., Zhu Y.N., Li X.Y., Yang Y.F., and Zuo J.P. Prevention of graft-versus-host disease by a novel immunosuppressant, (5R)-5-hydroxytriptolide (LLDT-8), through expansion of regulatory T cells. International Immunopharmacology 5 (2005) 1904-1913
    • (2005) International Immunopharmacology , vol.5 , pp. 1904-1913
    • Tang, W.1    Yang, Y.2    Zhang, F.3    Li, Y.C.4    Zhou, R.5    Wang, J.X.6    Zhu, Y.N.7    Li, X.Y.8    Yang, Y.F.9    Zuo, J.P.10
  • 22
    • 0034663944 scopus 로고    scopus 로고
    • Immunosuppressive activity of the Chinese medicinal plant Tripterygium wilfordii. I. Prolongation of rat cardiac and renal allograft survival by the PG27 extract and immunosuppressive synergy in combination therapy with cyclosporine
    • Wang J., Xu R., Jin R., Chen Z., and Fidler J.M. Immunosuppressive activity of the Chinese medicinal plant Tripterygium wilfordii. I. Prolongation of rat cardiac and renal allograft survival by the PG27 extract and immunosuppressive synergy in combination therapy with cyclosporine. Transplantation 70 (2000) 447-455
    • (2000) Transplantation , vol.70 , pp. 447-455
    • Wang, J.1    Xu, R.2    Jin, R.3    Chen, Z.4    Fidler, J.M.5
  • 23
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation tolerance
    • Wood K.J., and Sakaguchi S. Regulatory T cells in transplantation tolerance. Nature Reviews Immunology 3 (2003) 199-210
    • (2003) Nature Reviews Immunology , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.