Triptolide inhibits the differentiation of Th17 cells and suppresses collagen-induced arthritis

Scandinavian Journal of Immunology

Volumn 68, Issue 4, 2008, Pages 383-390

  Wang, Y ^a   Jia, L ^a   Wu, C Y ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 2; DITERPENOID; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 17; INTERLEUKIN 6; MESSENGER RNA; STAT3 PROTEIN; TRIPTERYGIUM WILFORDII EXTRACT; TRIPTOLIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTHRITIS; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DOWN REGULATION; DRUG MECHANISM; FEMALE; HELPER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN CELL; TH17 CELL; TRANSCRIPTION REGULATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BLOTTING, WESTERN; CELL DIFFERENTIATION; DITERPENES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPOXY COMPOUNDS; FEMALE; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-17; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; PHENANTHRENES; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 51349088720     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2008.02147.x     Document Type: Article

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