(5R)-5-hydroxytriptolide (LLDT-8), a novel triptolide analog mediates immunosuppressive effects in vitro and in vivo

International Immunopharmacology

Volumn 5, Issue 13-14, 2005, Pages 1895-1903

  Zhou, Ru ^a   Zhang, Fan ^a   He, Pei Lan ^a   Zhou, Wen Liang ^a   Wu, Qing Li ^a   Xu, Jian Yi ^a   Zhou, Yu ^a   Tang, Wei ^a   Li, Xiao Yu ^a   Yang, Yi Fu ^a   Li, Yuan Chao ^a   Zuo, Jian Ping ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

(5R) 5 hydroxytriptolide; Immunosuppression

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; CONCANAVALIN A; GAMMA INTERFERON; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 2; INTERLEUKIN 6; TRIPTOLIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONCENTRATION (PARAMETERS); CYTOKINE RELEASE; CYTOTOXICITY; DELAYED HYPERSENSITIVITY; DOSE RESPONSE; ERYTHROCYTE; FEMALE; HUMORAL IMMUNITY; IC 50; IMMUNOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LOW DRUG DOSE; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SHEEP; SPLEEN CELL; TH1 CELL;

ANIMALS; B-LYMPHOCYTES; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYTOKINES; DINITROFLUOROBENZENE; DISEASE MODELS, ANIMAL; DITERPENES; DRUGS, CHINESE HERBAL; FEMALE; HYPERSENSITIVITY, DELAYED; IMMUNOSUPPRESSIVE AGENTS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MALE; MICE; MICE, INBRED BALB C; SHEEP; SPLEEN; T-LYMPHOCYTES;

EID: 27744534829     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2005.06.009     Document Type: Article

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