Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism

American Journal of Physiology - Renal Physiology

Volumn 297, Issue 5, 2009, Pages

  Kemter, Elisabeth ^a   Rathkolb, Birgit ^a   Rozman, Jan ^b   Hans, Wolfgang ^b,c   Schrewe, Anja ^d   Landbrecht, Christina ^a   Klaften, Matthias ^b,c   Ivandic, Boris ^d   Fuchs, Helmut ^b,c   Gailus Durner, Valérie ^b,c   Klingenspor, Martin ^b   De Angelis, Martin Hrabé ^b,c   Wolf, Eckhard ^a   Wanke, Ruediger ^a   Aigner, Bernhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Kidney; N ethyl N nitrosourea; Renal disease; Umod

Indexed keywords

CHOLESTEROL; TAMM HORSFALL GLYCOPROTEIN; TRIACYLGLYCEROL; UREA; URIC ACID;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY FAT; BODY MASS; BODY WEIGHT; BONE METABOLISM; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; ENERGY METABOLISM; FEMALE; GENE FUNCTION; HENLE LOOP; HOMOZYGOSITY; HYPERCALCIURIA; KIDNEY CONCENTRATING CAPACITY; KIDNEY DYSFUNCTION; LIPID METABOLISM; MALE; METABOLIC RATE; MISSENSE MUTATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOPENIA; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL; UREA CYCLE; UREMIA; URIC ACID URINE LEVEL; URINARY EXCRETION;

EID: 70350721790     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00261.2009     Document Type: Article

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