Mutation of the Na+-K+-2Cl- cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia

American Journal of Physiology - Renal Physiology

Volumn 298, Issue 6, 2010, Pages

  Kemter, Elisabeth ^a   Rathkolb, Birgit ^a   Bankir, Lise ^b   Schrewe, Anja ^c,d   Hans, Wolfgang ^d   Landbrecht, Christina ^a   Klaften, Matthias ^d,e   Ivandic, Boris ^c   Fuchs, Helmut ^d,e   Gailus Durner, Valérie ^d,e   De Angelis, Martin Hrabé ^d,e   Wolf, Eckhard ^a   Wanke, Ruediger ^a   Aigner, Bernhard ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b CENTRE DE RECHERCHE DES CORDELIERS   (France)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

N ethyl N nitrosourea; Renin; Solute carrier family 12 member 1

Indexed keywords

CALCIUM; CREATININE; MAGNESIUM; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; UREA; URIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARTTER SYNDROME; BLOOD FLOW; CONTROLLED STUDY; CREATININE CLEARANCE; EXCRETION; FEMALE; HYPERMAGNESEMIA; HYPERRENINEMIA; HYPOTENSION; MALE; METABOLIC ALKALOSIS; MOUSE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOPENIA; POLYURIA; PRIORITY JOURNAL; UREA BLOOD LEVEL; URIC ACID URINE LEVEL; URINARY EXCRETION;

EID: 77952719683     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00522.2009     Document Type: Article

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