Overexpression of miR-125a in myelodysplastic syndrome CD34+ cells modulates NF-κB activation and enhances erythroid differentiation arrest

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Gañán Gómez, Irene ^a   Wei, Yue ^b   Yang, Hui ^b   Pierce, Sherry ^b   Bueso Ramos, Carlos ^b   Calin, George ^b   Del Carmen Boyano Adánez, María ^a   García Manero, Guillermo ^b  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; CYTARABINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LET 7E; MESSENGER RNA; MICRORNA; MICRORNA 125A; MICRORNA 125B; MICRORNA 99B; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; MIRN125 MICRORNA, HUMAN; MIRN99 MICRORNA, HUMAN; MIRNLET7 MICRORNA, HUMAN; TOLL LIKE RECEPTOR;

ARTICLE; CELL CYCLE ARREST; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; ERYTHROID CELL; ERYTHROPOIESIS; GENE CLUSTER; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; LEUKEMIA CELL LINE; MYELODYSPLASTIC SYNDROME; PATHOGENESIS; PROGNOSIS; SURVIVAL; TRANSCRIPTION REGULATION; BIOLOGICAL MODEL; CELL CYCLE CHECKPOINT; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HEMATOPOIETIC STEM CELL; K562 CELL LINE; METABOLISM; MORTALITY; MULTIGENE FAMILY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ANTIGENS, CD34; BIOMARKERS; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYTARABINE; ENZYME ACTIVATION; ERYTHROPOIESIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEMATOPOIETIC STEM CELLS; HUMANS; K562 CELLS; MICRORNAS; MODELS, BIOLOGICAL; MULTIGENE FAMILY; MYELODYSPLASTIC SYNDROMES; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROGNOSIS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84898606191     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093404     Document Type: Article

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