-
1
-
-
0035321067
-
The evolution and genetics of innate immunity
-
Kimbrell D.A., Beutler B. The evolution and genetics of innate immunity. Nat Rev Genet 2001, 2(4):256-267.
-
(2001)
Nat Rev Genet
, vol.2
, Issue.4
, pp. 256-267
-
-
Kimbrell, D.A.1
Beutler, B.2
-
2
-
-
34848852208
-
Toll-like receptors: key activators of leucocytes and regulator of haematopoiesis
-
McGettrick A.F., O'Neill L.A. Toll-like receptors: key activators of leucocytes and regulator of haematopoiesis. Br J Haematol 2007, 139(2):185-193.
-
(2007)
Br J Haematol
, vol.139
, Issue.2
, pp. 185-193
-
-
McGettrick, A.F.1
O'Neill, L.A.2
-
3
-
-
0035475338
-
Tumor necrosis factor receptor-associated factors (TRAFs)
-
Bradley J.R., Pober J.S. Tumor necrosis factor receptor-associated factors (TRAFs). Oncogene 2001, 20(44):6482-6491.
-
(2001)
Oncogene
, vol.20
, Issue.44
, pp. 6482-6491
-
-
Bradley, J.R.1
Pober, J.S.2
-
4
-
-
47249089097
-
IL-1, IL-18, and IL-33 families of cytokines
-
Arend W.P., Palmer G., Gabay C. IL-1, IL-18, and IL-33 families of cytokines. Immunol Rev 2008, 223:20-38.
-
(2008)
Immunol Rev
, vol.223
, pp. 20-38
-
-
Arend, W.P.1
Palmer, G.2
Gabay, C.3
-
5
-
-
32844469977
-
Lipopolysaccharide signaling in endothelial cells
-
Dauphinee S.M., Karsan A. Lipopolysaccharide signaling in endothelial cells. Lab Invest 2006, 86(1):9-22.
-
(2006)
Lab Invest
, vol.86
, Issue.1
, pp. 9-22
-
-
Dauphinee, S.M.1
Karsan, A.2
-
6
-
-
0035399769
-
Toll receptors in innate immunity
-
Imler J.L., Hoffmann J.A. Toll receptors in innate immunity. Trends Cell Biol 2001, 11(7):304-311.
-
(2001)
Trends Cell Biol
, vol.11
, Issue.7
, pp. 304-311
-
-
Imler, J.L.1
Hoffmann, J.A.2
-
7
-
-
0242720415
-
TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology
-
Wu H., Arron J.R. TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology. Bioessays 2003, 25(11):1096-1105.
-
(2003)
Bioessays
, vol.25
, Issue.11
, pp. 1096-1105
-
-
Wu, H.1
Arron, J.R.2
-
8
-
-
0038785874
-
Bacterial LPS and CpG DNA differentially induce gene expression profiles in mouse macrophages
-
Gao J.J., Diesl V., Wittmann T., et al. Bacterial LPS and CpG DNA differentially induce gene expression profiles in mouse macrophages. J Endotoxin Res 2003, 9(4):237-243.
-
(2003)
J Endotoxin Res
, vol.9
, Issue.4
, pp. 237-243
-
-
Gao, J.J.1
Diesl, V.2
Wittmann, T.3
-
10
-
-
0141670818
-
The interferon in TLR signaling: more than just antiviral
-
Hertzog P.J., O'Neill L.A., Hamilton J.A. The interferon in TLR signaling: more than just antiviral. Trends Immunol 2003, 24(10):534-539.
-
(2003)
Trends Immunol
, vol.24
, Issue.10
, pp. 534-539
-
-
Hertzog, P.J.1
O'Neill, L.A.2
Hamilton, J.A.3
-
11
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116(2):281-297.
-
(2004)
Cell
, vol.116
, Issue.2
, pp. 281-297
-
-
Bartel, D.P.1
-
12
-
-
33747608638
-
NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
-
Taganov K.D., Boldin M.P., Chang K.J., et al. NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci U S A 2006, 103(33):12481-12486.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, Issue.33
, pp. 12481-12486
-
-
Taganov, K.D.1
Boldin, M.P.2
Chang, K.J.3
-
13
-
-
41149130219
-
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder
-
O'Connell R.M., Rao D.S., Chaudhuri A.A., et al. Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. J Exp Med 2008, 205(3):585-594.
-
(2008)
J Exp Med
, vol.205
, Issue.3
, pp. 585-594
-
-
O'Connell, R.M.1
Rao, D.S.2
Chaudhuri, A.A.3
-
14
-
-
35348929402
-
A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection
-
Chen X.M., Splinter P.L., O'Hara S.P., et al. A cellular micro-RNA, let-7i, regulates Toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem 2007, 282(39):28929-28938.
-
(2007)
J Biol Chem
, vol.282
, Issue.39
, pp. 28929-28938
-
-
Chen, X.M.1
Splinter, P.L.2
O'Hara, S.P.3
-
15
-
-
70349439320
-
MiR-147, a microRNA that is induced upon toll-like receptor stimulation, regulates murine macrophage inflammatory responses
-
Liu G., Friggeri A., Yang Y., et al. miR-147, a microRNA that is induced upon toll-like receptor stimulation, regulates murine macrophage inflammatory responses. Proc Natl Acad Sci U S A 2009, 106(37):15819-15824.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.37
, pp. 15819-15824
-
-
Liu, G.1
Friggeri, A.2
Yang, Y.3
-
16
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki A., Iliopoulos D., Arranz A., et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 2009, 31(2):220-231.
-
(2009)
Immunity
, vol.31
, Issue.2
, pp. 220-231
-
-
Androulidaki, A.1
Iliopoulos, D.2
Arranz, A.3
-
17
-
-
46449092527
-
A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis
-
Labbaye C., Spinello I., Quaranta M.T., et al. A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis. Nat Cell Biol 2008, 10(7):788-801.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.7
, pp. 788-801
-
-
Labbaye, C.1
Spinello, I.2
Quaranta, M.T.3
-
18
-
-
73849121794
-
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype
-
Starczynowski D.T., Kuchenbauer F., Argiropoulos B., et al. Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med 2010, 16:49-58.
-
(2010)
Nat Med
, vol.16
, pp. 49-58
-
-
Starczynowski, D.T.1
Kuchenbauer, F.2
Argiropoulos, B.3
-
19
-
-
0346727524
-
MicroRNAs modulate hematopoietic lineage differentiation
-
Chen C.Z., Li L., Lodish H.F., et al. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004, 303(5654):83-86.
-
(2004)
Science
, vol.303
, Issue.5654
, pp. 83-86
-
-
Chen, C.Z.1
Li, L.2
Lodish, H.F.3
-
20
-
-
22344437262
-
Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow
-
Ueda Y., Kondo M., Kelsoe G. Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow. J Exp Med 2005, 201(11):1771-1780.
-
(2005)
J Exp Med
, vol.201
, Issue.11
, pp. 1771-1780
-
-
Ueda, Y.1
Kondo, M.2
Kelsoe, G.3
-
21
-
-
33744978765
-
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
-
Nagai Y., Garrett K.P., Ohta S., et al. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 2006, 24(6):801-812.
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 801-812
-
-
Nagai, Y.1
Garrett, K.P.2
Ohta, S.3
-
22
-
-
46949097612
-
TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice
-
Tang M., Wei X., Guo Y., et al. TAK1 is required for the survival of hematopoietic cells and hepatocytes in mice. J Exp Med 2008, 205(7):1611-1619.
-
(2008)
J Exp Med
, vol.205
, Issue.7
, pp. 1611-1619
-
-
Tang, M.1
Wei, X.2
Guo, Y.3
-
23
-
-
0141483064
-
Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?
-
Passegue E., Jamieson C.H., Ailles L.E., et al. Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?. Proc Natl Acad Sci U S A 2003, 100(Suppl 1):11842-11849.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.1 SUPPL.
, pp. 11842-11849
-
-
Passegue, E.1
Jamieson, C.H.2
Ailles, L.E.3
-
24
-
-
77950530165
-
The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms
-
[Epub ahead of print]
-
Vardiman J.W. The World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues: an overview with emphasis on the myeloid neoplasms. Chem Biol Interact 2009, [Epub ahead of print].
-
(2009)
Chem Biol Interact
-
-
Vardiman, J.W.1
-
25
-
-
27744455719
-
Gains, losses and complex karyotypes in myeloid disorders: a light at the end of the tunnel
-
Alvarez S., Cigudosa J.C. Gains, losses and complex karyotypes in myeloid disorders: a light at the end of the tunnel. Hematol Oncol 2005, 23(1):18-25.
-
(2005)
Hematol Oncol
, vol.23
, Issue.1
, pp. 18-25
-
-
Alvarez, S.1
Cigudosa, J.C.2
-
27
-
-
34548841921
-
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML
-
Heuser M., Argiropoulos B., Kuchenbauer F., et al. MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. Blood 2007, 110(5):1639-1647.
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1639-1647
-
-
Heuser, M.1
Argiropoulos, B.2
Kuchenbauer, F.3
-
28
-
-
75649149337
-
Modelling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal
-
Heuser M., Sly L.M., Argiropoulos B., et al. Modelling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal. Blood 2009, 114:3983-3993.
-
(2009)
Blood
, vol.114
, pp. 3983-3993
-
-
Heuser, M.1
Sly, L.M.2
Argiropoulos, B.3
-
29
-
-
33845263501
-
High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
-
Heuser M., Beutel G., Krauter J., et al. High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood 2006, 108(12):3898-3905.
-
(2006)
Blood
, vol.108
, Issue.12
, pp. 3898-3905
-
-
Heuser, M.1
Beutel, G.2
Krauter, J.3
-
30
-
-
0036093475
-
FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model
-
Kelly L.M., Liu Q., Kutok J.L., et al. FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model. Blood 2002, 99(1):310-318.
-
(2002)
Blood
, vol.99
, Issue.1
, pp. 310-318
-
-
Kelly, L.M.1
Liu, Q.2
Kutok, J.L.3
-
31
-
-
6344253247
-
Interleukin-1beta maintains an apoptosis-resistant phenotype in the blast cells of acute myeloid leukaemia via multiple pathways
-
Turzanski J., Grundy M., Russell N.H., et al. Interleukin-1beta maintains an apoptosis-resistant phenotype in the blast cells of acute myeloid leukaemia via multiple pathways. Leukemia 2004, 18(10):1662-1670.
-
(2004)
Leukemia
, vol.18
, Issue.10
, pp. 1662-1670
-
-
Turzanski, J.1
Grundy, M.2
Russell, N.H.3
-
32
-
-
0034326624
-
TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies
-
Zapata J.M., Krajewska M., Krajewski S., et al. TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J Immunol 2000, 165(9):5084-5096.
-
(2000)
J Immunol
, vol.165
, Issue.9
, pp. 5084-5096
-
-
Zapata, J.M.1
Krajewska, M.2
Krajewski, S.3
-
33
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman M.L., Neering S.J., Upchurch D., et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 2001, 98(8):2301-2307.
-
(2001)
Blood
, vol.98
, Issue.8
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
-
34
-
-
85047692516
-
Signalling pathways of the TNF superfamily: a double-edged sword
-
Aggarwal B.B. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 2003, 3(9):745-756.
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.9
, pp. 745-756
-
-
Aggarwal, B.B.1
-
35
-
-
0032762178
-
Frequent expression of the variant CD30 in human malignant myeloid and lymphoid neoplasms
-
Horie R., Gattei V., Ito K., et al. Frequent expression of the variant CD30 in human malignant myeloid and lymphoid neoplasms. Am J Pathol 1999, 155(6):2029-2041.
-
(1999)
Am J Pathol
, vol.155
, Issue.6
, pp. 2029-2041
-
-
Horie, R.1
Gattei, V.2
Ito, K.3
-
36
-
-
84934436278
-
LMP1 TRAFficking activates growth and survival pathways
-
Soni V., Cahir-McFarland E., Kieff E. LMP1 TRAFficking activates growth and survival pathways. Adv Exp Med Biol 2007, 597:173-187.
-
(2007)
Adv Exp Med Biol
, vol.597
, pp. 173-187
-
-
Soni, V.1
Cahir-McFarland, E.2
Kieff, E.3
-
37
-
-
0036841640
-
CD40L induces proliferation, self-renewal, rescue from apoptosis, and production of cytokines by CD40-expressing AML blasts
-
Aldinucci D., Poletto D., Nanni P., et al. CD40L induces proliferation, self-renewal, rescue from apoptosis, and production of cytokines by CD40-expressing AML blasts. Exp Hematol 2002, 30(11):1283-1292.
-
(2002)
Exp Hematol
, vol.30
, Issue.11
, pp. 1283-1292
-
-
Aldinucci, D.1
Poletto, D.2
Nanni, P.3
-
38
-
-
33646344737
-
Circulating levels and clinical significance of soluble CD40 in patients with hematologic malignancies
-
Hock B.D., McKenzie J.L., Patton N.W., et al. Circulating levels and clinical significance of soluble CD40 in patients with hematologic malignancies. Cancer 2006, 106(10):2148-2157.
-
(2006)
Cancer
, vol.106
, Issue.10
, pp. 2148-2157
-
-
Hock, B.D.1
McKenzie, J.L.2
Patton, N.W.3
-
39
-
-
77950547739
-
The roles of ASK family proteins in stress responses and diseases
-
Hattori K., Naguro I., Runchel C., et al. The roles of ASK family proteins in stress responses and diseases. Cell Commun Signal 2009, 7:9.
-
(2009)
Cell Commun Signal
, vol.7
, pp. 9
-
-
Hattori, K.1
Naguro, I.2
Runchel, C.3
-
40
-
-
33847636024
-
ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis
-
Yan W., Arai A., Aoki M., et al. ASK1 is activated by arsenic trioxide in leukemic cells through accumulation of reactive oxygen species and may play a negative role in induction of apoptosis. Biochem Biophys Res Commun 2007, 355(4):1038-1044.
-
(2007)
Biochem Biophys Res Commun
, vol.355
, Issue.4
, pp. 1038-1044
-
-
Yan, W.1
Arai, A.2
Aoki, M.3
-
41
-
-
58149170439
-
Azinomycin epoxide induces activation of apoptosis signal-regulating kinase 1 (ASK1) and caspase 3 in a HIF-1alpha-independent manner in human leukaemia myeloid macrophages
-
Casely-Hayford M.A., Nicholas S.A., Sumbayev V.V. Azinomycin epoxide induces activation of apoptosis signal-regulating kinase 1 (ASK1) and caspase 3 in a HIF-1alpha-independent manner in human leukaemia myeloid macrophages. Eur J Pharmacol 2009, 602(2-3):262-267.
-
(2009)
Eur J Pharmacol
, vol.602
, Issue.2-3
, pp. 262-267
-
-
Casely-Hayford, M.A.1
Nicholas, S.A.2
Sumbayev, V.V.3
-
42
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H., Nishida E., Irie K., et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997, 275(5296):90-94.
-
(1997)
Science
, vol.275
, Issue.5296
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
-
43
-
-
44449109622
-
The c-myc apoptotic response is not intrinsic to blocking terminal myeloid differentiation
-
D'Angelo S., Liebermann D., Hoffman B. The c-myc apoptotic response is not intrinsic to blocking terminal myeloid differentiation. J Cell Physiol 2008, 216(1):120-127.
-
(2008)
J Cell Physiol
, vol.216
, Issue.1
, pp. 120-127
-
-
D'Angelo, S.1
Liebermann, D.2
Hoffman, B.3
-
44
-
-
42949083345
-
MicroRNA expression in cytogenetically normal acute myeloid leukemia
-
Marcucci G., Radmacher M.D., Maharry K., et al. MicroRNA expression in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008, 358(18):1919-1928.
-
(2008)
N Engl J Med
, vol.358
, Issue.18
, pp. 1919-1928
-
-
Marcucci, G.1
Radmacher, M.D.2
Maharry, K.3
-
45
-
-
34247648712
-
MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis
-
Debernardi S., Skoulakis S., Molloy G., et al. MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis. Leukemia 2007, 21(5):912-916.
-
(2007)
Leukemia
, vol.21
, Issue.5
, pp. 912-916
-
-
Debernardi, S.1
Skoulakis, S.2
Molloy, G.3
-
46
-
-
33846515640
-
Myelodysplastic syndromes: the complexity of stem-cell diseases
-
Corey S.J., Minden M.D., Barber D.L., et al. Myelodysplastic syndromes: the complexity of stem-cell diseases. Nat Rev Cancer 2007, 7(2):118-129.
-
(2007)
Nat Rev Cancer
, vol.7
, Issue.2
, pp. 118-129
-
-
Corey, S.J.1
Minden, M.D.2
Barber, D.L.3
-
47
-
-
70349256226
-
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
-
Vardiman J.W., Thiele J., Arber D.A., et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009, 114(5):937-951.
-
(2009)
Blood
, vol.114
, Issue.5
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
-
48
-
-
0242361657
-
Visceral leishmaniasis masquerading as myelodysplasia
-
Kopterides P., Halikias S., Tsavaris N. Visceral leishmaniasis masquerading as myelodysplasia. Am J Hematol 2003, 74(3):198-199.
-
(2003)
Am J Hematol
, vol.74
, Issue.3
, pp. 198-199
-
-
Kopterides, P.1
Halikias, S.2
Tsavaris, N.3
-
49
-
-
0027985811
-
Chronic parvovirus infection mimicking myelodysplastic syndrome in a child with subclinical immunodeficiency
-
Hasle H., Kerndrup G., Jacobsen B.B., et al. Chronic parvovirus infection mimicking myelodysplastic syndrome in a child with subclinical immunodeficiency. Am J Pediatr Hematol Oncol 1994, 16(4):329-333.
-
(1994)
Am J Pediatr Hematol Oncol
, vol.16
, Issue.4
, pp. 329-333
-
-
Hasle, H.1
Kerndrup, G.2
Jacobsen, B.B.3
-
50
-
-
33749438404
-
Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
-
List A., Dewald G., Bennett J., et al. Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med 2006, 355(14):1456-1465.
-
(2006)
N Engl J Med
, vol.355
, Issue.14
, pp. 1456-1465
-
-
List, A.1
Dewald, G.2
Bennett, J.3
-
51
-
-
22044450619
-
NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
-
Lin Y.W., Slape C., Zhang Z., et al. NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. Blood 2005, 106(1):287-295.
-
(2005)
Blood
, vol.106
, Issue.1
, pp. 287-295
-
-
Lin, Y.W.1
Slape, C.2
Zhang, Z.3
-
52
-
-
52949153952
-
Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell
-
Chung Y.J., Choi C.W., Slape C., et al. Transplantation of a myelodysplastic syndrome by a long-term repopulating hematopoietic cell. Proc Natl Acad Sci U S A 2008, 105(37):14088-14093.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.37
, pp. 14088-14093
-
-
Chung, Y.J.1
Choi, C.W.2
Slape, C.3
-
53
-
-
24344437303
-
Role of nucleophosmin in embryonic development and tumorigenesis
-
Grisendi S., Bernardi R., Rossi M., et al. Role of nucleophosmin in embryonic development and tumorigenesis. Nature 2005, 437(7055):147-153.
-
(2005)
Nature
, vol.437
, Issue.7055
, pp. 147-153
-
-
Grisendi, S.1
Bernardi, R.2
Rossi, M.3
-
54
-
-
85047694750
-
EVI1 induces myelodysplastic syndrome in mice
-
Buonamici S., Li D., Chi Y., et al. EVI1 induces myelodysplastic syndrome in mice. J Clin Invest 2004, 114(5):713-719.
-
(2004)
J Clin Invest
, vol.114
, Issue.5
, pp. 713-719
-
-
Buonamici, S.1
Li, D.2
Chi, Y.3
-
55
-
-
2942627120
-
Anemia, thrombocytopenia, leukocytosis, extramedullary hematopoiesis, and impaired progenitor function in Pten+/-SHIP-/- mice: a novel model of myelodysplasia
-
Moody J.L., Xu L., Helgason C.D., et al. Anemia, thrombocytopenia, leukocytosis, extramedullary hematopoiesis, and impaired progenitor function in Pten+/-SHIP-/- mice: a novel model of myelodysplasia. Blood 2004, 103(12):4503-4510.
-
(2004)
Blood
, vol.103
, Issue.12
, pp. 4503-4510
-
-
Moody, J.L.1
Xu, L.2
Helgason, C.D.3
-
56
-
-
45349089427
-
Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo
-
Minella A.C., Loeb K.R., Knecht A., et al. Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo. Genes Dev 2008, 22(12):1677-1689.
-
(2008)
Genes Dev
, vol.22
, Issue.12
, pp. 1677-1689
-
-
Minella, A.C.1
Loeb, K.R.2
Knecht, A.3
-
57
-
-
54049149411
-
Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS
-
Zhou L., Nguyen A.N., Sohal D., et al. Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS. Blood 2008, 112(8):3434-3443.
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3434-3443
-
-
Zhou, L.1
Nguyen, A.N.2
Sohal, D.3
-
58
-
-
34548066815
-
Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1
-
Peng J., Kitchen S.M., West R.A., et al. Myeloproliferative defects following targeting of the Drf1 gene encoding the mammalian diaphanous related formin mDia1. Cancer Res 2007, 67(16):7565-7571.
-
(2007)
Cancer Res
, vol.67
, Issue.16
, pp. 7565-7571
-
-
Peng, J.1
Kitchen, S.M.2
West, R.A.3
-
59
-
-
67650859652
-
Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer
-
Ebert B.L. Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer. Leukemia 2009, 23(7):1252-1256.
-
(2009)
Leukemia
, vol.23
, Issue.7
, pp. 1252-1256
-
-
Ebert, B.L.1
-
60
-
-
38349088899
-
Identification of RPS14 as a 5q-syndrome gene by RNA interference screen
-
Ebert B.L., Pretz J., Bosco J., et al. Identification of RPS14 as a 5q-syndrome gene by RNA interference screen. Nature 2008, 451(7176):335-339.
-
(2008)
Nature
, vol.451
, Issue.7176
, pp. 335-339
-
-
Ebert, B.L.1
Pretz, J.2
Bosco, J.3
-
61
-
-
34548128327
-
Common deleted genes in the 5q-syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice
-
Lehmann S., O'Kelly J., Raynaud S., et al. Common deleted genes in the 5q-syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice. Leukemia 2007, 21(9):1931-1936.
-
(2007)
Leukemia
, vol.21
, Issue.9
, pp. 1931-1936
-
-
Lehmann, S.1
O'Kelly, J.2
Raynaud, S.3
-
62
-
-
73849128091
-
A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome
-
Barlow J.L., Drynan L.F., Hewett D.R., et al. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q-syndrome. Nat Med 2010, 16:59-66.
-
(2010)
Nat Med
, vol.16
, pp. 59-66
-
-
Barlow, J.L.1
Drynan, L.F.2
Hewett, D.R.3
-
63
-
-
28444479122
-
NF-kappaB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
-
Kerbauy D.M., Lesnikov V., Abbasi N., et al. NF-kappaB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs). Blood 2005, 106(12):3917-3925.
-
(2005)
Blood
, vol.106
, Issue.12
, pp. 3917-3925
-
-
Kerbauy, D.M.1
Lesnikov, V.2
Abbasi, N.3
-
64
-
-
34250333058
-
NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia
-
Fabre C., Carvalho G., Tasdemir E., et al. NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia. Oncogene 2007, 26(28):4071-4083.
-
(2007)
Oncogene
, vol.26
, Issue.28
, pp. 4071-4083
-
-
Fabre, C.1
Carvalho, G.2
Tasdemir, E.3
-
65
-
-
0033562798
-
An essential role for NF-kappaB in human CD34(+) bone marrow cell survival
-
Pyatt D.W., Stillman W.S., Yang Y., et al. An essential role for NF-kappaB in human CD34(+) bone marrow cell survival. Blood 1999, 93(10):3302-3308.
-
(1999)
Blood
, vol.93
, Issue.10
, pp. 3302-3308
-
-
Pyatt, D.W.1
Stillman, W.S.2
Yang, Y.3
-
66
-
-
31544448567
-
NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome
-
Braun T., Carvalho G., Coquelle A., et al. NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome. Blood 2006, 107(3):1156-1165.
-
(2006)
Blood
, vol.107
, Issue.3
, pp. 1156-1165
-
-
Braun, T.1
Carvalho, G.2
Coquelle, A.3
-
67
-
-
20244364979
-
Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha
-
Rupec R.A., Jundt F., Rebholz B., et al. Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity 2005, 22(4):479-491.
-
(2005)
Immunity
, vol.22
, Issue.4
, pp. 479-491
-
-
Rupec, R.A.1
Jundt, F.2
Rebholz, B.3
-
68
-
-
33947255107
-
Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes
-
Maratheftis C.I., Andreakos E., Moutsopoulos H.M., et al. Toll-like receptor-4 is up-regulated in hematopoietic progenitor cells and contributes to increased apoptosis in myelodysplastic syndromes. Clin Cancer Res 2007, 13(4):1154-1160.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.4
, pp. 1154-1160
-
-
Maratheftis, C.I.1
Andreakos, E.2
Moutsopoulos, H.M.3
-
69
-
-
35448934364
-
Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome
-
Kerbauy D.B., Deeg H.J. Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Exp Hematol 2007, 35(11):1739-1746.
-
(2007)
Exp Hematol
, vol.35
, Issue.11
, pp. 1739-1746
-
-
Kerbauy, D.B.1
Deeg, H.J.2
-
70
-
-
0037111773
-
Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow
-
Hofmann W.K., de Vos S., Komor M., et al. Characterization of gene expression of CD34+ cells from normal and myelodysplastic bone marrow. Blood 2002, 100(10):3553-3560.
-
(2002)
Blood
, vol.100
, Issue.10
, pp. 3553-3560
-
-
Hofmann, W.K.1
de Vos, S.2
Komor, M.3
-
71
-
-
0037411227
-
Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes
-
Sawanobori M., Yamaguchi S., Hasegawa M., et al. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Leuk Res 2003, 27(7):583-591.
-
(2003)
Leuk Res
, vol.27
, Issue.7
, pp. 583-591
-
-
Sawanobori, M.1
Yamaguchi, S.2
Hasegawa, M.3
-
72
-
-
54049105351
-
High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival
-
Starczynowski D.T., Vercauteren S., Telenius A., et al. High-resolution whole genome tiling path array CGH analysis of CD34+ cells from patients with low-risk myelodysplastic syndromes reveals cryptic copy number alterations and predicts overall and leukemia-free survival. Blood 2008, 112(8):3412-3424.
-
(2008)
Blood
, vol.112
, Issue.8
, pp. 3412-3424
-
-
Starczynowski, D.T.1
Vercauteren, S.2
Telenius, A.3
-
73
-
-
38949123096
-
Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
-
Gondek L.P., Tiu R., O'Keefe C.L., et al. Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 2008, 111(3):1534-1542.
-
(2008)
Blood
, vol.111
, Issue.3
, pp. 1534-1542
-
-
Gondek, L.P.1
Tiu, R.2
O'Keefe, C.L.3
-
74
-
-
0027086859
-
Measurement of serum cytokine levels in patients with myelodysplastic syndromes
-
Verhoef G.E., De Schouwer P., Ceuppens J.L., et al. Measurement of serum cytokine levels in patients with myelodysplastic syndromes. Leukemia 1992, 6(12):1268-1272.
-
(1992)
Leukemia
, vol.6
, Issue.12
, pp. 1268-1272
-
-
Verhoef, G.E.1
De Schouwer, P.2
Ceuppens, J.L.3
-
75
-
-
0029154403
-
Spontaneous cytokine overproduction by peripheral blood mononuclear cells from patients with myelodysplastic syndromes and aplastic anemia
-
Koike M., Ishiyama T., Tomoyasu S., et al. Spontaneous cytokine overproduction by peripheral blood mononuclear cells from patients with myelodysplastic syndromes and aplastic anemia. Leuk Res 1995, 19(9):639-644.
-
(1995)
Leuk Res
, vol.19
, Issue.9
, pp. 639-644
-
-
Koike, M.1
Ishiyama, T.2
Tomoyasu, S.3
-
76
-
-
0026780525
-
Increased serum interleukin 6 levels in patients with myelodysplastic syndromes
-
Herold M., Schmalzl F., Zwierzina H. Increased serum interleukin 6 levels in patients with myelodysplastic syndromes. Leuk Res 1992, 16(6-7):585-588.
-
(1992)
Leuk Res
, vol.16
, Issue.6-7
, pp. 585-588
-
-
Herold, M.1
Schmalzl, F.2
Zwierzina, H.3
-
77
-
-
0036369821
-
Circulating levels of thrombopoietic and inflammatory cytokines in patients with acute myeloblastic leukemia and myelodysplastic syndrome
-
Hsu H.C., Lee Y.M., Tsai W.H., et al. Circulating levels of thrombopoietic and inflammatory cytokines in patients with acute myeloblastic leukemia and myelodysplastic syndrome. Oncology 2002, 63(1):64-69.
-
(2002)
Oncology
, vol.63
, Issue.1
, pp. 64-69
-
-
Hsu, H.C.1
Lee, Y.M.2
Tsai, W.H.3
-
78
-
-
17644368573
-
Interleukin-6: from basic science to medicine-40 years in immunology
-
Kishimoto T. Interleukin-6: from basic science to medicine-40 years in immunology. Annu Rev Immunol 2005, 23:1-21.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 1-21
-
-
Kishimoto, T.1
-
79
-
-
0026672334
-
Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus
-
Hawley R.G., Fong A.Z., Burns B.F., et al. Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus. J Exp Med 1992, 176(4):1149-1163.
-
(1992)
J Exp Med
, vol.176
, Issue.4
, pp. 1149-1163
-
-
Hawley, R.G.1
Fong, A.Z.2
Burns, B.F.3
-
80
-
-
0033168605
-
Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha
-
Corral L.G., Haslett P.A., Muller G.W., et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 1999, 163(1):380-386.
-
(1999)
J Immunol
, vol.163
, Issue.1
, pp. 380-386
-
-
Corral, L.G.1
Haslett, P.A.2
Muller, G.W.3
-
81
-
-
57749114621
-
250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies
-
Dunbar A.J., Gondek L.P., O'Keefe C.L., et al. 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies. Cancer Res 2008, 68(24):10349-10357.
-
(2008)
Cancer Res
, vol.68
, Issue.24
, pp. 10349-10357
-
-
Dunbar, A.J.1
Gondek, L.P.2
O'Keefe, C.L.3
-
82
-
-
0035839450
-
A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation
-
Arron J.R., Vologodskaia M., Wong B.R., et al. A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation. J Biol Chem 2001, 276(32):30011-30017.
-
(2001)
J Biol Chem
, vol.276
, Issue.32
, pp. 30011-30017
-
-
Arron, J.R.1
Vologodskaia, M.2
Wong, B.R.3
-
83
-
-
0035865603
-
Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12)
-
Kuno Y., Abe A., Emi N., et al. Constitutive kinase activation of the TEL-Syk fusion gene in myelodysplastic syndrome with t(9;12)(q22;p12). Blood 2001, 97(4):1050-1055.
-
(2001)
Blood
, vol.97
, Issue.4
, pp. 1050-1055
-
-
Kuno, Y.1
Abe, A.2
Emi, N.3
-
84
-
-
1542398767
-
TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways
-
Kanie T., Abe A., Matsuda T., et al. TEL-Syk fusion constitutively activates PI3-K/Akt, MAPK and JAK2-independent STAT5 signal pathways. Leukemia 2004, 18(3):548-555.
-
(2004)
Leukemia
, vol.18
, Issue.3
, pp. 548-555
-
-
Kanie, T.1
Abe, A.2
Matsuda, T.3
-
85
-
-
0035399733
-
IL-1 induced chemokine production through the association of Syk with TNF receptor-associated factor-6 in nasal fibroblast lines
-
Yamada T., Fujieda S., Yanagi S., et al. IL-1 induced chemokine production through the association of Syk with TNF receptor-associated factor-6 in nasal fibroblast lines. J Immunol 2001, 167(1):283-288.
-
(2001)
J Immunol
, vol.167
, Issue.1
, pp. 283-288
-
-
Yamada, T.1
Fujieda, S.2
Yanagi, S.3
-
86
-
-
24944476696
-
Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome
-
Brakensiek K., Langer F., Schlegelberger B., et al. Hypermethylation of the suppressor of cytokine signalling-1 (SOCS-1) in myelodysplastic syndrome. Br J Haematol 2005, 130(2):209-217.
-
(2005)
Br J Haematol
, vol.130
, Issue.2
, pp. 209-217
-
-
Brakensiek, K.1
Langer, F.2
Schlegelberger, B.3
-
87
-
-
17144366936
-
Aberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia
-
Johan M.F., Bowen D.T., Frew M.E., et al. Aberrant methylation of the negative regulators RASSFIA, SHP-1 and SOCS-1 in myelodysplastic syndromes and acute myeloid leukaemia. Br J Haematol 2005, 129(1):60-65.
-
(2005)
Br J Haematol
, vol.129
, Issue.1
, pp. 60-65
-
-
Johan, M.F.1
Bowen, D.T.2
Frew, M.E.3
-
88
-
-
52949090018
-
SOCS regulation of the JAK/STAT signalling pathway
-
Croker B.A., Kiu H., Nicholson S.E. SOCS regulation of the JAK/STAT signalling pathway. Semin Cell Dev Biol 2008, 19(4):414-422.
-
(2008)
Semin Cell Dev Biol
, vol.19
, Issue.4
, pp. 414-422
-
-
Croker, B.A.1
Kiu, H.2
Nicholson, S.E.3
-
89
-
-
66149147424
-
Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism
-
Scott M.J., Liu S., Shapiro R.A., et al. Endotoxin uptake in mouse liver is blocked by endotoxin pretreatment through a suppressor of cytokine signaling-1-dependent mechanism. Hepatology 2009, 49(5):1695-1708.
-
(2009)
Hepatology
, vol.49
, Issue.5
, pp. 1695-1708
-
-
Scott, M.J.1
Liu, S.2
Shapiro, R.A.3
-
90
-
-
0036624741
-
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications
-
Mitsiades N., Mitsiades C.S., Poulaki V., et al. Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications. Blood 2002, 99(11):4079-4086.
-
(2002)
Blood
, vol.99
, Issue.11
, pp. 4079-4086
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Poulaki, V.3
-
91
-
-
59849096576
-
Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression
-
Noman A.S., Koide N., Hassan F., et al. Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression. Innate Immun 2009, 15(1):33-41.
-
(2009)
Innate Immun
, vol.15
, Issue.1
, pp. 33-41
-
-
Noman, A.S.1
Koide, N.2
Hassan, F.3
-
92
-
-
60849098162
-
Single-agent lenalidomide induces complete remission of acute myeloid leukemia in patients with isolated trisomy 13
-
Fehniger T.A., Byrd J.C., Marcucci G., et al. Single-agent lenalidomide induces complete remission of acute myeloid leukemia in patients with isolated trisomy 13. Blood 2009, 113(5):1002-1005.
-
(2009)
Blood
, vol.113
, Issue.5
, pp. 1002-1005
-
-
Fehniger, T.A.1
Byrd, J.C.2
Marcucci, G.3
-
93
-
-
13444256401
-
Efficacy of lenalidomide in myelodysplastic syndromes
-
List A., Kurtin S., Roe D.J., et al. Efficacy of lenalidomide in myelodysplastic syndromes. N Engl J Med 2005, 352(6):549-557.
-
(2005)
N Engl J Med
, vol.352
, Issue.6
, pp. 549-557
-
-
List, A.1
Kurtin, S.2
Roe, D.J.3
|