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Volumn 105, Issue 4, 2014, Pages 363-369

Epigenetic dysregulation in glioma

Author keywords

DNA methylation; Epigenetics; Glioma stem cell; Histone modification; Non coding RNA

Indexed keywords

UNTRANSLATED RNA;

EID: 84898405904     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/cas.12379     Document Type: Article
Times cited : (50)

References (73)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 2005; 352: 987-96.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 2
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359: 492-507.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 3
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007; 128: 683-92.
    • (2007) Cell , vol.128 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 4
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Noushmehr H, Weisenberger DJ, Diefes K et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell 2010; 17: 510-22.
    • (2010) Cancer Cell , vol.17 , pp. 510-522
    • Noushmehr, H.1    Weisenberger, D.J.2    Diefes, K.3
  • 5
    • 84885074034 scopus 로고    scopus 로고
    • The somatic genomic landscape of glioblastoma
    • Brennan CW, Verhaak RG, McKenna A et al. The somatic genomic landscape of glioblastoma. Cell 2013; 155: 462-77.
    • (2013) Cell , vol.155 , pp. 462-477
    • Brennan, C.W.1    Verhaak, R.G.2    McKenna, A.3
  • 6
    • 84863621527 scopus 로고    scopus 로고
    • Cancer epigenetics: from mechanism to therapy
    • Dawson MA, Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell 2012; 150: 12-27.
    • (2012) Cell , vol.150 , pp. 12-27
    • Dawson, M.A.1    Kouzarides, T.2
  • 7
    • 34250305146 scopus 로고    scopus 로고
    • Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
    • Birney E, Stamatoyannopoulos JA, Dutta A et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature 2007; 447: 799-816.
    • (2007) Nature , vol.447 , pp. 799-816
    • Birney, E.1    Stamatoyannopoulos, J.A.2    Dutta, A.3
  • 8
    • 34249088350 scopus 로고    scopus 로고
    • Genome-wide transcription and the implications for genomic organization
    • Kapranov P, Willingham AT, Gingeras TR. Genome-wide transcription and the implications for genomic organization. Nat Rev Genet 2007; 8: 413-23.
    • (2007) Nat Rev Genet , vol.8 , pp. 413-423
    • Kapranov, P.1    Willingham, A.T.2    Gingeras, T.R.3
  • 9
    • 80052869283 scopus 로고    scopus 로고
    • lincRNAs act in the circuitry controlling pluripotency and differentiation
    • Guttman M, Donaghey J, Carey BW et al. lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature 2011; 477: 295-300.
    • (2011) Nature , vol.477 , pp. 295-300
    • Guttman, M.1    Donaghey, J.2    Carey, B.W.3
  • 11
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller M. Non-coding RNAs in human disease. Nat Rev Genet 2011; 12: 861-74.
    • (2011) Nat Rev Genet , vol.12 , pp. 861-874
    • Esteller, M.1
  • 14
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa JP. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004; 4: 988-93.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 15
    • 79953123510 scopus 로고    scopus 로고
    • Breast cancer methylomes establish an epigenomic foundation for metastasis
    • 75ra25
    • Fang F, Turcan S, Rimner A et al. Breast cancer methylomes establish an epigenomic foundation for metastasis. Sci Transl Med 2011; 3: 75ra25.
    • (2011) Sci Transl Med , vol.3
    • Fang, F.1    Turcan, S.2    Rimner, A.3
  • 16
    • 84865160485 scopus 로고    scopus 로고
    • Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma
    • Shinjo K, Okamoto Y, An B et al. Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma. Carcinogenesis 2012; 33: 1277-85.
    • (2012) Carcinogenesis , vol.33 , pp. 1277-1285
    • Shinjo, K.1    Okamoto, Y.2    An, B.3
  • 17
    • 83355163405 scopus 로고    scopus 로고
    • Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin
    • Lai A, Kharbanda S, Pope WB et al. Evidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin. J Clin Oncol 2011; 29: 4482-90.
    • (2011) J Clin Oncol , vol.29 , pp. 4482-4490
    • Lai, A.1    Kharbanda, S.2    Pope, W.B.3
  • 18
    • 78650019179 scopus 로고    scopus 로고
    • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
    • Figueroa ME, Abdel-Wahab O, Lu C et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 2010; 18: 553-67.
    • (2010) Cancer Cell , vol.18 , pp. 553-567
    • Figueroa, M.E.1    Abdel-Wahab, O.2    Lu, C.3
  • 19
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang L, White DW, Gross S et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009; 462: 739-44.
    • (2009) Nature , vol.462 , pp. 739-744
    • Dang, L.1    White, D.W.2    Gross, S.3
  • 20
    • 84858796263 scopus 로고    scopus 로고
    • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
    • Turcan S, Rohle D, Goenka A et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature 2012; 483: 479-83.
    • (2012) Nature , vol.483 , pp. 479-483
    • Turcan, S.1    Rohle, D.2    Goenka, A.3
  • 21
    • 78751662908 scopus 로고    scopus 로고
    • The Polycomb complex PRC2 and its mark in life
    • Margueron R, Reinberg D. The Polycomb complex PRC2 and its mark in life. Nature 2011; 469: 343-9.
    • (2011) Nature , vol.469 , pp. 343-349
    • Margueron, R.1    Reinberg, D.2
  • 22
    • 51349105905 scopus 로고    scopus 로고
    • Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
    • Gal-Yam EN, Egger G, Iniguez L et al. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci U S A 2008; 105: 12979-84.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 12979-12984
    • Gal-Yam, E.N.1    Egger, G.2    Iniguez, L.3
  • 23
    • 44349131472 scopus 로고    scopus 로고
    • Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation
    • Kondo Y, Shen L, Cheng AS et al. Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation. Nat Genet 2008; 40: 741-50.
    • (2008) Nat Genet , vol.40 , pp. 741-750
    • Kondo, Y.1    Shen, L.2    Cheng, A.S.3
  • 24
    • 84861883921 scopus 로고    scopus 로고
    • Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk
    • Brinkman AB, Gu H, Bartels SJ et al. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-talk. Genome Res 2012; 22: 1128-38.
    • (2012) Genome Res , vol.22 , pp. 1128-1138
    • Brinkman, A.B.1    Gu, H.2    Bartels, S.J.3
  • 25
    • 0037215568 scopus 로고    scopus 로고
    • Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer
    • Kondo Y, Shen L, Issa JP. Critical role of histone methylation in tumor suppressor gene silencing in colorectal cancer. Mol Cell Biol 2003; 23: 206-15.
    • (2003) Mol Cell Biol , vol.23 , pp. 206-215
    • Kondo, Y.1    Shen, L.2    Issa, J.P.3
  • 26
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: patterns and paradigms
    • Cedar H, Bergman Y. Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet 2009; 10: 295-304.
    • (2009) Nat Rev Genet , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 27
    • 84555189745 scopus 로고    scopus 로고
    • DNA methylation: TET proteins-guardians of CpG islands?
    • Williams K, Christensen J, Helin K. DNA methylation: TET proteins-guardians of CpG islands? EMBO Rep 2011; 13: 28-35.
    • (2011) EMBO Rep , vol.13 , pp. 28-35
    • Williams, K.1    Christensen, J.2    Helin, K.3
  • 28
    • 0036340237 scopus 로고    scopus 로고
    • The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans
    • Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, Kingston RE. The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans. Mol Cell Biol 2002; 22: 6070-8.
    • (2002) Mol Cell Biol , vol.22 , pp. 6070-6078
    • Levine, S.S.1    Weiss, A.2    Erdjument-Bromage, H.3    Shao, Z.4    Tempst, P.5    Kingston, R.E.6
  • 29
    • 55449105221 scopus 로고    scopus 로고
    • Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains
    • Ku M, Koche RP, Rheinbay E et al. Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet 2008; 4: e1000242.
    • (2008) PLoS Genet , vol.4
    • Ku, M.1    Koche, R.P.2    Rheinbay, E.3
  • 30
    • 76149142791 scopus 로고    scopus 로고
    • Polycomb complexes act redundantly to repress genomic repeats and genes
    • Leeb M, Pasini D, Novatchkova M, Jaritz M, Helin K, Wutz A. Polycomb complexes act redundantly to repress genomic repeats and genes. Genes Dev 2010; 24: 265-76.
    • (2010) Genes Dev , vol.24 , pp. 265-276
    • Leeb, M.1    Pasini, D.2    Novatchkova, M.3    Jaritz, M.4    Helin, K.5    Wutz, A.6
  • 31
    • 77956282774 scopus 로고    scopus 로고
    • Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells
    • Majewski IJ, Ritchie ME, Phipson B et al. Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood 2010; 116: 731-9.
    • (2010) Blood , vol.116 , pp. 731-739
    • Majewski, I.J.1    Ritchie, M.E.2    Phipson, B.3
  • 32
    • 0242667922 scopus 로고    scopus 로고
    • Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
    • Molofsky AV, Pardal R, Iwashita T, Park IK, Clarke MF, Morrison SJ. Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 2003; 425: 962-7.
    • (2003) Nature , vol.425 , pp. 962-967
    • Molofsky, A.V.1    Pardal, R.2    Iwashita, T.3    Park, I.K.4    Clarke, M.F.5    Morrison, S.J.6
  • 33
    • 0037673984 scopus 로고    scopus 로고
    • Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
    • Lessard J, Sauvageau G. Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 2003; 423: 255-60.
    • (2003) Nature , vol.423 , pp. 255-260
    • Lessard, J.1    Sauvageau, G.2
  • 34
    • 77957680712 scopus 로고    scopus 로고
    • Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
    • Pereira JD, Sansom SN, Smith J, Dobenecker MW, Tarakhovsky A, Livesey FJ. Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex. Proc Natl Acad Sci U S A 2010; 107: 15957-62.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 15957-15962
    • Pereira, J.D.1    Sansom, S.N.2    Smith, J.3    Dobenecker, M.W.4    Tarakhovsky, A.5    Livesey, F.J.6
  • 35
    • 77957357566 scopus 로고    scopus 로고
    • TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration
    • Palacios D, Mozzetta C, Consalvi S et al. TNF/p38alpha/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration. Cell Stem Cell 2010; 7: 455-69.
    • (2010) Cell Stem Cell , vol.7 , pp. 455-469
    • Palacios, D.1    Mozzetta, C.2    Consalvi, S.3
  • 36
    • 84880857612 scopus 로고    scopus 로고
    • Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma
    • Natsume A, Ito M, Katsushima K et al. Chromatin regulator PRC2 is a key regulator of epigenetic plasticity in glioblastoma. Cancer Res 2013; 73: 4559-70.
    • (2013) Cancer Res , vol.73 , pp. 4559-4570
    • Natsume, A.1    Ito, M.2    Katsushima, K.3
  • 37
    • 84862777348 scopus 로고    scopus 로고
    • Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
    • Schwartzentruber J, Korshunov A, Liu XY et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012; 482: 226-31.
    • (2012) Nature , vol.482 , pp. 226-231
    • Schwartzentruber, J.1    Korshunov, A.2    Liu, X.Y.3
  • 38
    • 84862777410 scopus 로고    scopus 로고
    • Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
    • Wu G, Broniscer A, McEachron TA et al. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 2012; 44: 251-3.
    • (2012) Nat Genet , vol.44 , pp. 251-253
    • Wu, G.1    Broniscer, A.2    McEachron, T.A.3
  • 39
    • 84887617868 scopus 로고    scopus 로고
    • Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas
    • Bender S, Tang Y, Lindroth AM et al. Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas. Cancer Cell 2013; 24: 660-72.
    • (2013) Cancer Cell , vol.24 , pp. 660-672
    • Bender, S.1    Tang, Y.2    Lindroth, A.M.3
  • 40
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M et al. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002; 419: 624-9.
    • (2002) Nature , vol.419 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3
  • 41
    • 84864567410 scopus 로고    scopus 로고
    • Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia
    • Tanaka S, Miyagi S, Sashida G et al. Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia. Blood 2012; 120: 1107-17.
    • (2012) Blood , vol.120 , pp. 1107-1117
    • Tanaka, S.1    Miyagi, S.2    Sashida, G.3
  • 42
    • 84863252826 scopus 로고    scopus 로고
    • EZH2 couples pancreatic regeneration to neoplastic progression
    • Mallen-St Clair J, Soydaner-Azeloglu R, Lee KE et al. EZH2 couples pancreatic regeneration to neoplastic progression. Genes Dev 2012; 26: 439-44.
    • (2012) Genes Dev , vol.26 , pp. 439-444
    • Mallen-St Clair, J.1    Soydaner-Azeloglu, R.2    Lee, K.E.3
  • 43
    • 84859475727 scopus 로고    scopus 로고
    • Polycomb repressive complex 2 is required for MLL-AF9 leukemia
    • Neff T, Sinha AU, Kluk MJ et al. Polycomb repressive complex 2 is required for MLL-AF9 leukemia. Proc Natl Acad Sci U S A 2012; 109: 5028-33.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5028-5033
    • Neff, T.1    Sinha, A.U.2    Kluk, M.J.3
  • 44
    • 84867606428 scopus 로고    scopus 로고
    • Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma
    • Sturm D, Witt H, Hovestadt V et al. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma. Cancer Cell 2012; 22: 425-37.
    • (2012) Cancer Cell , vol.22 , pp. 425-437
    • Sturm, D.1    Witt, H.2    Hovestadt, V.3
  • 45
    • 78651463452 scopus 로고    scopus 로고
    • Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
    • Xu W, Yang H, Liu Y et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases. Cancer Cell 2011; 19: 17-30.
    • (2011) Cancer Cell , vol.19 , pp. 17-30
    • Xu, W.1    Yang, H.2    Liu, Y.3
  • 46
    • 84858796262 scopus 로고    scopus 로고
    • IDH mutation impairs histone demethylation and results in a block to cell differentiation
    • Lu C, Ward PS, Kapoor GS et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation. Nature 2012; 483: 474-8.
    • (2012) Nature , vol.483 , pp. 474-478
    • Lu, C.1    Ward, P.S.2    Kapoor, G.S.3
  • 47
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-97.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 48
    • 58849163959 scopus 로고    scopus 로고
    • MicroRNAs: key regulators of stem cells
    • Gangaraju VK, Lin H. MicroRNAs: key regulators of stem cells. Nat Rev 2009; 10: 116-25.
    • (2009) Nat Rev , vol.10 , pp. 116-125
    • Gangaraju, V.K.1    Lin, H.2
  • 49
    • 80054937128 scopus 로고    scopus 로고
    • CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells
    • Schraivogel D, Weinmann L, Beier D et al. CAMTA1 is a novel tumour suppressor regulated by miR-9/9* in glioblastoma stem cells. EMBO J 2011; 30: 4309-22.
    • (2011) EMBO J , vol.30 , pp. 4309-4322
    • Schraivogel, D.1    Weinmann, L.2    Beier, D.3
  • 50
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 51
    • 65349115320 scopus 로고    scopus 로고
    • SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma
    • Son MJ, Woolard K, Nam DH, Lee J, Fine HA. SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 2009; 4: 440-52.
    • (2009) Cell Stem Cell , vol.4 , pp. 440-452
    • Son, M.J.1    Woolard, K.2    Nam, D.H.3    Lee, J.4    Fine, H.A.5
  • 52
    • 77953478056 scopus 로고    scopus 로고
    • De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures
    • Ernst A, Campos B, Meier J et al. De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures. Oncogene 2010; 29: 3411-22.
    • (2010) Oncogene , vol.29 , pp. 3411-3422
    • Ernst, A.1    Campos, B.2    Meier, J.3
  • 53
    • 48949116262 scopus 로고    scopus 로고
    • miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
    • Silber J, Lim DA, Petritsch C et al. miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med 2008; 6: 14.
    • (2008) BMC Med , vol.6 , pp. 14
    • Silber, J.1    Lim, D.A.2    Petritsch, C.3
  • 54
    • 70350221952 scopus 로고    scopus 로고
    • MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
    • Li Y, Guessous F, Zhang Y et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res 2009; 69: 7569-76.
    • (2009) Cancer Res , vol.69 , pp. 7569-7576
    • Li, Y.1    Guessous, F.2    Zhang, Y.3
  • 55
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • Fan X, Matsui W, Khaki L et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res 2006; 66: 7445-52.
    • (2006) Cancer Res , vol.66 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3
  • 56
    • 75349108271 scopus 로고    scopus 로고
    • Notch promotes radioresistance of glioma stem cells
    • Wang J, Wakeman TP, Lathia JD et al. Notch promotes radioresistance of glioma stem cells. Stem Cells 2010; 28: 17-28.
    • (2010) Stem Cells , vol.28 , pp. 17-28
    • Wang, J.1    Wakeman, T.P.2    Lathia, J.D.3
  • 57
    • 56449126945 scopus 로고    scopus 로고
    • Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
    • Godlewski J, Nowicki MO, Bronisz A et al. Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res 2008; 68: 9125-30.
    • (2008) Cancer Res , vol.68 , pp. 9125-9130
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3
  • 58
    • 84883189850 scopus 로고    scopus 로고
    • MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells
    • Peruzzi P, Bronisz A, Nowicki MO et al. MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. Neuro Oncol 2013; 15: 1212-24.
    • (2013) Neuro Oncol , vol.15 , pp. 1212-1224
    • Peruzzi, P.1    Bronisz, A.2    Nowicki, M.O.3
  • 59
    • 69949129056 scopus 로고    scopus 로고
    • Cancer stem cells: mirage or reality?
    • Gupta PB, Chaffer CL, Weinberg RA. Cancer stem cells: mirage or reality? Nat Med 2009; 15: 1010-2.
    • (2009) Nat Med , vol.15 , pp. 1010-1012
    • Gupta, P.B.1    Chaffer, C.L.2    Weinberg, R.A.3
  • 60
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
    • Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer 2009; 9: 265-73.
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 61
    • 80051967505 scopus 로고    scopus 로고
    • Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
    • Gupta PB, Fillmore CM, Jiang G et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell 2011; 146: 633-44.
    • (2011) Cell , vol.146 , pp. 633-644
    • Gupta, P.B.1    Fillmore, C.M.2    Jiang, G.3
  • 62
    • 79958849271 scopus 로고    scopus 로고
    • Heterogeneity maintenance in glioblastoma: a social network
    • Bonavia R, Inda MM, Cavenee WK, Furnari FB. Heterogeneity maintenance in glioblastoma: a social network. Cancer Res 2011; 71: 4055-60.
    • (2011) Cancer Res , vol.71 , pp. 4055-4060
    • Bonavia, R.1    Inda, M.M.2    Cavenee, W.K.3    Furnari, F.B.4
  • 63
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • Lee J, Kotliarova S, Kotliarov Y et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006; 9: 391-403.
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3
  • 64
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • Chen J, Li Y, Yu TS et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012; 488: 522-6.
    • (2012) Nature , vol.488 , pp. 522-526
    • Chen, J.1    Li, Y.2    Yu, T.S.3
  • 65
    • 84875755046 scopus 로고    scopus 로고
    • Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
    • Cheng L, Huang Z, Zhou W et al. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell 2013; 153: 139-52.
    • (2013) Cell , vol.153 , pp. 139-152
    • Cheng, L.1    Huang, Z.2    Zhou, W.3
  • 66
    • 33646872978 scopus 로고    scopus 로고
    • Chromatin signatures of pluripotent cell lines
    • Azuara V, Perry P, Sauer S et al. Chromatin signatures of pluripotent cell lines. Nat Cell Biol 2006; 8: 532-8.
    • (2006) Nat Cell Biol , vol.8 , pp. 532-538
    • Azuara, V.1    Perry, P.2    Sauer, S.3
  • 67
    • 33646865180 scopus 로고    scopus 로고
    • Control of developmental regulators by Polycomb in human embryonic stem cells
    • Lee TI, Jenner RG, Boyer LA et al. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006; 125: 301-13.
    • (2006) Cell , vol.125 , pp. 301-313
    • Lee, T.I.1    Jenner, R.G.2    Boyer, L.A.3
  • 68
    • 84864992390 scopus 로고    scopus 로고
    • Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells
    • Katsushima K, Shinjo K, Natsume A et al. Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells. J Biol Chem 2012; 287: 27396-406.
    • (2012) J Biol Chem , vol.287 , pp. 27396-27406
    • Katsushima, K.1    Shinjo, K.2    Natsume, A.3
  • 69
    • 65349141942 scopus 로고    scopus 로고
    • Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study
    • Galanis E, Jaeckle KA, Maurer MJ et al. Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study. J Clin Oncol 2009; 27: 2052-8.
    • (2009) J Clin Oncol , vol.27 , pp. 2052-2058
    • Galanis, E.1    Jaeckle, K.A.2    Maurer, M.J.3
  • 70
    • 84859538161 scopus 로고    scopus 로고
    • Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study
    • Friday BB, Anderson SK, Buckner J et al. Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study. Neuro Oncol 2012; 14: 215-21.
    • (2012) Neuro Oncol , vol.14 , pp. 215-221
    • Friday, B.B.1    Anderson, S.K.2    Buckner, J.3
  • 71
    • 79953748673 scopus 로고    scopus 로고
    • A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
    • Wang KC, Yang YW, Liu B et al. A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature 2011; 472: 120-4.
    • (2011) Nature , vol.472 , pp. 120-124
    • Wang, K.C.1    Yang, Y.W.2    Liu, B.3
  • 72
    • 82155186923 scopus 로고    scopus 로고
    • The emergence of lncRNAs in cancer biology
    • Prensner JR, Chinnaiyan AM. The emergence of lncRNAs in cancer biology. Cancer Discov 2011; 1: 391-407.
    • (2011) Cancer Discov , vol.1 , pp. 391-407
    • Prensner, J.R.1    Chinnaiyan, A.M.2
  • 73
    • 84868683051 scopus 로고    scopus 로고
    • Regulation of mammalian cell differentiation by long non-coding RNAs
    • Hu W, Alvarez-Dominguez JR, Lodish HF. Regulation of mammalian cell differentiation by long non-coding RNAs. EMBO Rep 2012; 13: 971-83.
    • (2012) EMBO Rep , vol.13 , pp. 971-983
    • Hu, W.1    Alvarez-Dominguez, J.R.2    Lodish, H.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.