-
1
-
-
77951209408
-
Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif
-
Aghajanian A, Wittchen ES, Campbell SL, and Burridge K. Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. PLoS One 4: E8045, 2009
-
(2009)
PLoS One
, vol.4
-
-
Aghajanian, A.1
Wittchen, E.S.2
Campbell, S.L.3
Burridge, K.4
-
2
-
-
79959213985
-
Bacterial protein toxins that modify host regulatory GTPases
-
Aktories K. Bacterial protein toxins that modify host regulatory GTPases. Nat Rev Microbiol 9: 487-498, 2011
-
(2011)
Nat Rev Microbiol
, vol.9
, pp. 487-498
-
-
Aktories, K.1
-
3
-
-
70350418724
-
Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions
-
Albiges-Rizo C, Destaing O, Fourcade B, Planus E, and Block MR. Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions. J Cell Sci 122: 3037-3049, 2009
-
(2009)
J Cell Sci
, vol.122
, pp. 3037-3049
-
-
Albiges-Rizo, C.1
Destaing, O.2
Fourcade, B.3
Planus, E.4
Block, M.R.5
-
4
-
-
84866133072
-
Reactive oxygen species in health and disease
-
Alfadda AA and Sallam RM. Reactive oxygen species in health and disease. J Biomed Biotechnol 2012: 936486, 2012
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 936486
-
-
Alfadda, A.A.1
Sallam, R.M.2
-
5
-
-
80053444351
-
Filopodia and adhesion in cancer cell motility
-
Arjonen A, Kaukonen R, and Ivaska J. Filopodia and adhesion in cancer cell motility. Cell Adh Migr 5: 421-430, 2011
-
(2011)
Cell Adh Migr
, vol.5
, pp. 421-430
-
-
Arjonen, A.1
Kaukonen, R.2
Ivaska, J.3
-
6
-
-
33846794822
-
The NOX family of ROSgenerating NADPH oxidases: Physiology and pathophysiology
-
Bedard K and Krause KH. The NOX family of ROSgenerating NADPH oxidases: Physiology and pathophysiology. Physiol Rev 87: 245-313, 2007
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
7
-
-
0034213327
-
Rho gtpases and their effector proteins
-
Bishop AL and Hall A. Rho GTPases and their effector proteins. Biochem J 348 Pt 2: 241-255, 2000
-
(2000)
Biochem J
, vol.348
, Issue.PART 2
, pp. 241-255
-
-
Bishop, A.L.1
Hall, A.2
-
8
-
-
84866432422
-
Reactive oxygen species: From health to disease
-
Brieger K, Schiavone S, Miller FJ, Jr., and Krause KH. Reactive oxygen species: From health to disease. Swiss Med Wkly 142: W13659, 2012
-
(2012)
Swiss Med Wkly
, vol.142
, pp. 13659
-
-
Brieger, K.1
Schiavone, S.2
Miller Jr., F.J.3
Krause, K.H.4
-
9
-
-
74949129817
-
Chronic hypoxia augments depolarizationinduced ca2 + sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of rhoa
-
Broughton BR, Jernigan NL, Norton CE, Walker BR, and Resta TC. Chronic hypoxia augments depolarizationinduced Ca2 + sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA. Am J Physiol Lung Cell Mol Physiol 298: L232-L242, 2010
-
(2010)
Am J Physiol Lung Cell Mol Physiol
, vol.298
-
-
Broughton, B.R.1
Jernigan, N.L.2
Norton, C.E.3
Walker, B.R.4
Resta, T.C.5
-
10
-
-
54549091120
-
From cells to organs: Building polarized tissue
-
Bryant DM and Mostov KE. From cells to organs: Building polarized tissue. Nat Rev Mol Cell Biol 9: 887-901, 2008
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 887-901
-
-
Bryant, D.M.1
Mostov, K.E.2
-
11
-
-
65349137933
-
Redox regulation of ephrin/ integrin cross-Talk
-
Buricchi F, Giannoni E, Grimaldi G, Parri M, Raugei G, Ramponi G, and Chiarugi P. Redox regulation of ephrin/ integrin cross-Talk. Cell Adh Migr 1: 33-42, 2007
-
(2007)
Cell Adh Migr
, vol.1
, pp. 33-42
-
-
Buricchi, F.1
Giannoni, E.2
Grimaldi, G.3
Parri, M.4
Raugei, G.5
Ramponi, G.6
Chiarugi, P.7
-
12
-
-
70349341899
-
Downstream targets and intracellular compartmentalization in Nox signaling
-
Chen K, Craige SE, and Keaney JF, Jr. Downstream targets and intracellular compartmentalization in Nox signaling. Antioxid Redox Signal 11: 2467-2480, 2009
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2467-2480
-
-
Chen, K.1
Craige, S.E.2
Keaney Jr., J.F.3
-
13
-
-
84874433733
-
Regulation of small gtpases by gefs gaps, and gdis
-
Cherfils J and Zeghouf M. Regulation of small GTPases by GEFs, GAPs, and GDIs. Physiol Rev 93: 269-309, 2013
-
(2013)
Physiol Rev
, vol.93
, pp. 269-309
-
-
Cherfils, J.1
Zeghouf, M.2
-
14
-
-
34848927902
-
The many faces of actin: Matching assembly factors with cellular structures
-
Chhabra ES and Higgs HN. The many faces of actin: Matching assembly factors with cellular structures. Nat Cell Biol 9: 1110-1121, 2007
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1110-1121
-
-
Chhabra, E.S.1
Higgs, H.N.2
-
15
-
-
76249131229
-
Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells
-
Chi AY, Waypa GB, Mungai PT, and Schumacker PT. Prolonged hypoxia increases ROS signaling and RhoA activation in pulmonary artery smooth muscle and endothelial cells. Antioxid Redox Signal 12: 603-610, 2010
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 603-610
-
-
Chi, A.Y.1
Waypa, G.B.2
Mungai, P.T.3
Schumacker, P.T.4
-
16
-
-
26244449496
-
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells
-
Czuchra A, Wu X, Meyer H, van Hengel J, Schroeder T, Geffers R, Rottner K, and Brakebusch C. Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells. Mol Biol Cell 16: 4473-4484, 2005
-
(2005)
Mol Biol Cell
, vol.16
, pp. 4473-4484
-
-
Czuchra, A.1
Wu, X.2
Meyer, H.3
Van Hengel, J.4
Schroeder, T.5
Geffers, R.6
Rottner, K.7
Brakebusch, C.8
-
17
-
-
34447522003
-
Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells
-
Dada LA, Novoa E, Lecuona E, Sun H, and Sznajder JI. Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells. J Cell Sci 120: 2214-2222, 2007
-
(2007)
J Cell Sci
, vol.120
, pp. 2214-2222
-
-
Dada, L.A.1
Novoa, E.2
Lecuona, E.3
Sun, H.4
Sznajder, J.I.5
-
18
-
-
0035893961
-
The actin cytoskeleton response to oxidants: From small heat shock protein phosphorylation to changes in the redox state of actin itself
-
Dalle-Donne I, Rossi R, Milzani A, Di Simplicio P, and Colombo R. The actin cytoskeleton response to oxidants: From small heat shock protein phosphorylation to changes in the redox state of actin itself. Free Radic Biol Med 31: 1624-1632, 2001
-
(2001)
Free Radic Biol Med
, vol.31
, pp. 1624-1632
-
-
Dalle-Donne, I.1
Rossi, R.2
Milzani, A.3
Di Simplicio, P.4
Colombo, R.5
-
19
-
-
76549123909
-
Generation of branched actin networks: Assembly and regulation of the N-WASP and WAVE molecular machines
-
Derivery E and Gautreau A. Generation of branched actin networks: Assembly and regulation of the N-WASP and WAVE molecular machines. Bioessays 32: 119-131, 2010
-
(2010)
Bioessays
, vol.32
, pp. 119-131
-
-
Derivery, E.1
Gautreau, A.2
-
20
-
-
73949101383
-
Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation
-
Diaz B, Shani G, Pass I, Anderson D, Quintavalle M, and Courtneidge SA. Tks5-dependent, nox-mediated generation of reactive oxygen species is necessary for invadopodia formation. Sci Signal 2: Ra53, 2009
-
(2009)
Sci Signal
, vol.2
, pp. 53
-
-
Diaz, B.1
Shani, G.2
Pass, I.3
Anderson, D.4
Quintavalle, M.5
Courtneidge, S.A.6
-
21
-
-
0033233262
-
P40phox associates with the neutrophil Triton X-100-insoluble cytoskeletal fraction and PMA-Activated membrane skeleton: A comparative study with P67phox and P47phox
-
El Benna J, Dang PM, Andrieu V, Vergnaud S, Dewas C, Cachia O, Fay M, Morel F, Chollet-Martin S, Hakim J, and Gougerot-Pocidalo MA. P40phox associates with the neutrophil Triton X-100-insoluble cytoskeletal fraction and PMA-Activated membrane skeleton: A comparative study with P67phox and P47phox. J Leukoc Biol 66: 1014-1020, 1999
-
(1999)
J Leukoc Biol
, vol.66
, pp. 1014-1020
-
-
El Benna, J.1
Dang, P.M.2
Andrieu, V.3
Vergnaud, S.4
Dewas, C.5
Cachia, O.6
Fay, M.7
Morel, F.8
Chollet-Martin, S.9
Hakim, J.10
Gougerot-Pocidalo, M.A.11
-
22
-
-
0028227249
-
Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation
-
El Benna J, Ruedi JM, and Babior BM. Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Transfer of Rac2 and the cytosolic oxidase components p47phox and p67phox to the submembranous actin cytoskeleton during oxidase activation. J Biol Chem 269: 6729-6734, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 6729-6734
-
-
El Benna, J.1
Ruedi, J.M.2
Babior, B.M.3
-
23
-
-
33747362096
-
Redox regulation of beta-Actin during integrin-mediated cell adhesion
-
Fiaschi T, Cozzi G, Raugei G, Formigli L, Ramponi G, and Chiarugi P. Redox regulation of beta-Actin during integrin-mediated cell adhesion. J Biol Chem 281: 22983-22991, 2006
-
(2006)
J Biol Chem
, vol.281
, pp. 22983-22991
-
-
Fiaschi, T.1
Cozzi, G.2
Raugei, G.3
Formigli, L.4
Ramponi, G.5
Chiarugi, P.6
-
24
-
-
75749107907
-
Cell mechanics and the cytoskeleton
-
Fletcher DA and Mullins RD. Cell mechanics and the cytoskeleton. Nature 463: 485-492, 2010
-
(2010)
Nature
, vol.463
, pp. 485-492
-
-
Fletcher, D.A.1
Mullins, R.D.2
-
25
-
-
67649528138
-
Collective cell migration in morphogenesis, regeneration and cancer
-
Friedl P and Gilmour D. Collective cell migration in morphogenesis, regeneration and cancer. Nat Rev Mol Cell Biol 10: 445-457, 2009
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 445-457
-
-
Friedl, P.1
Gilmour, D.2
-
26
-
-
1542495339
-
Proteolytic and non-proteolytic migration of tumour cells and leucocytes
-
Friedl P and Wolf K. Proteolytic and non-proteolytic migration of tumour cells and leucocytes. Biochem Soc Symp 70: 277-285, 2003
-
(2003)
Biochem Soc Symp
, vol.70
, pp. 277-285
-
-
Friedl, P.1
Wolf, K.2
-
27
-
-
67349276010
-
RhoA effector mDia1 is required for PI 3-kinase-dependent actin remodeling and spreading by thrombin in platelets
-
Gao G, Chen L, Dong B, Gu H, Dong H, Pan Y, Gao Y, and Chen X. RhoA effector mDia1 is required for PI 3-kinase-dependent actin remodeling and spreading by thrombin in platelets. Biochem Biophys Res Commun 385: 439-444, 2009
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 439-444
-
-
Gao, G.1
Chen, L.2
Dong, B.3
Gu, H.4
Dong, H.5
Pan, Y.6
Gao, Y.7
Chen, X.8
-
29
-
-
36849088611
-
Cdc42 regulates cofilin during the establishment of neuronal polarity
-
Garvalov BK, Flynn KC, Neukirchen D, Meyn L, Teusch N, Wu X, Brakebusch C, Bamburg JR, and Bradke F. Cdc42 regulates cofilin during the establishment of neuronal polarity. J Neurosci 27: 13117-13129, 2007
-
(2007)
J Neurosci
, vol.27
, pp. 13117-13129
-
-
Garvalov, B.K.1
Flynn, K.C.2
Neukirchen, D.3
Meyn, L.4
Teusch, N.5
Wu, X.6
Brakebusch, C.7
Bamburg, J.R.8
Bradke, F.9
-
30
-
-
33745209498
-
NADPH oxidases: New kids on the block
-
Geiszt M. NADPH oxidases: New kids on the block. Cardiovasc Res 71: 289-299, 2006
-
(2006)
Cardiovasc Res
, vol.71
, pp. 289-299
-
-
Geiszt, M.1
-
31
-
-
77958098686
-
A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells
-
Gianni D, Taulet N, Zhang H, DerMardirossian C, Kister J, Martinez L, Roush WR, Brown SJ, Bokoch GM, and Rosen H. A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. ACS Chem Biol 5: 981-993, 2010
-
(2010)
ACS Chem Biol
, vol.5
, pp. 981-993
-
-
Gianni, D.1
Taulet, N.2
Zhang, H.3
DerMardirossian, C.4
Kister, J.5
Martinez, L.6
Roush, W.R.7
Brown, S.J.8
Bokoch, G.M.9
Rosen, H.10
-
32
-
-
33749037156
-
The ARP2/3 complex: An actin nucleator comes of age
-
Goley ED and Welch MD. The ARP2/3 complex: An actin nucleator comes of age. Nat Rev Mol Cell Biol 7: 713-726, 2006
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 713-726
-
-
Goley, E.D.1
Welch, M.D.2
-
33
-
-
0035995644
-
TNFalpha activates c-Jun amino terminal kinase through p47(phox
-
Gu Y, Xu YC, Wu RF, Souza RF, Nwariaku FE, and Terada LS. TNFalpha activates c-Jun amino terminal kinase through p47(phox). Exp Cell Res 272: 62-74, 2002
-
(2002)
Exp Cell Res
, vol.272
, pp. 62-74
-
-
Gu, Y.1
Xu, Y.C.2
Wu, R.F.3
Souza, R.F.4
Nwariaku, F.E.5
Terada, L.S.6
-
34
-
-
50149083752
-
Mammalian rho gtpases new insights into their functions from in vivo studies
-
Heasman SJ and Ridley AJ. Mammalian Rho GTPases: New insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9: 690-701, 2008
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
35
-
-
79251582896
-
Redox control of GTPases: From molecular mechanisms to functional significance in health and disease
-
Heo J. Redox control of GTPases: From molecular mechanisms to functional significance in health and disease. Antioxid Redox Signal 14: 689-724, 2011
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 689-724
-
-
Heo, J.1
-
36
-
-
24744433531
-
Mechanism of redox-mediated guanine nucleotide exchange on redox-Active Rho GTPases
-
Heo J and Campbell SL. Mechanism of redox-mediated guanine nucleotide exchange on redox-Active Rho GTPases. J Biol Chem 280: 31003-31010, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 31003-31010
-
-
Heo, J.1
Campbell, S.L.2
-
37
-
-
33845253796
-
Redox regulation of RhoA
-
Heo J, Raines KW, Mocanu V, and Campbell SL. Redox regulation of RhoA. Biochemistry 45: 14481-14489, 2006
-
(2006)
Biochemistry
, vol.45
, pp. 14481-14489
-
-
Heo, J.1
Raines, K.W.2
Mocanu, V.3
Campbell, S.L.4
-
38
-
-
79955713787
-
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool
-
Herzog D, Loetscher P, van Hengel J, Knusel S, Brakebusch C, Taylor V, Suter U, and Relvas JB. The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool. J Neurosci 31: 5120-5130, 2011
-
(2011)
J Neurosci
, vol.31
, pp. 5120-5130
-
-
Herzog, D.1
Loetscher, P.2
Van Hengel, J.3
Knusel, S.4
Brakebusch, C.5
Taylor, V.6
Suter, U.7
Relvas, J.B.8
-
39
-
-
0030756377
-
Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the nadph oxidase complex evidence for a novel cycle of phosphorylation and dephosphorylation
-
Heyworth PG, Robinson JM, Ding J, Ellis BA, and Badwey JA. Cofilin undergoes rapid dephosphorylation in stimulated neutrophils and translocates to ruffled membranes enriched in products of the NADPH oxidase complex. Evidence for a novel cycle of phosphorylation and dephosphorylation. Histochem Cell Biol 108: 221-233, 1997
-
(1997)
Histochem Cell Biol
, vol.108
, pp. 221-233
-
-
Heyworth, P.G.1
Robinson, J.M.2
Ding, J.3
Ellis, B.A.4
Badwey, J.A.5
-
40
-
-
18844438774
-
Formin proteins: A domain-based approach
-
Higgs HN. Formin proteins: A domain-based approach. Trends Biochem Sci 30: 342-353, 2005
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 342-353
-
-
Higgs, H.N.1
-
41
-
-
0034911925
-
Regulation of actin filament network formation through ARP2/3 complex: Activation by a diverse array of proteins
-
Higgs HN and Pollard TD. Regulation of actin filament network formation through ARP2/3 complex: Activation by a diverse array of proteins. Annu Rev Biochem 70: 649-676, 2001
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 649-676
-
-
Higgs, H.N.1
Pollard, T.D.2
-
42
-
-
78650348130
-
Conformational dynamics of actin: Effectors and implications for biological function
-
Hild G, Bugyi B, and Nyitrai M. Conformational dynamics of actin: Effectors and implications for biological function. Cytoskeleton (Hoboken) 67: 609-629, 2010
-
(2010)
Cytoskeleton (Hoboken
, vol.67
, pp. 609-629
-
-
Hild, G.1
Bugyi, B.2
Nyitrai, M.3
-
43
-
-
33645285957
-
Regulation of NADPH oxidases: The role of Rac proteins
-
Hordijk PL. Regulation of NADPH oxidases: The role of Rac proteins. Circ Res 98: 453-462, 2006
-
(2006)
Circ Res
, vol.98
, pp. 453-462
-
-
Hordijk, P.L.1
-
45
-
-
84856535275
-
Redox regulation of cell migration and adhesion
-
Hurd TR, DeGennaro M, and Lehmann R. Redox regulation of cell migration and adhesion. Trends Cell Biol 22: 107-115, 2012
-
(2012)
Trends Cell Biol
, vol.22
, pp. 107-115
-
-
Hurd, T.R.1
DeGennaro, M.2
Lehmann, R.3
-
46
-
-
79952329256
-
RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes
-
Jackson B, Peyrollier K, Pedersen E, Basse A, Karlsson R, Wang Z, Lefever T, Ochsenbein AM, Schmidt G, Aktories K, Stanley A, Quondamatteo F, Ladwein M, Rottner K, van Hengel J, and Brakebusch C. RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes. Mol Biol Cell 22: 593-605, 2011
-
(2011)
Mol Biol Cell
, vol.22
, pp. 593-605
-
-
Jackson, B.1
Peyrollier, K.2
Pedersen, E.3
Basse, A.4
Karlsson, R.5
Wang, Z.6
Lefever, T.7
Ochsenbein, A.M.8
Schmidt, G.9
Aktories, K.10
Stanley, A.11
Quondamatteo, F.12
Ladwein, M.13
Rottner, K.14
Van Hengel, J.15
Brakebusch, C.16
-
47
-
-
27944479854
-
Rho GTPases biochemistry and biology
-
Jaffe AB and Hall A. Rho GTPases: Biochemistry and biology. Annu Rev Cell Dev Biol 21: 247-269, 2005
-
(2005)
Annu Rev Cell Dev Biol
, vol.21
, pp. 247-269
-
-
Jaffe, A.B.1
Hall, A.2
-
48
-
-
52649126946
-
Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2 + sensitization in pulmonary vascular smooth muscle following chronic hypoxia
-
Jernigan NL, Walker BR, and Resta TC. Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2 + sensitization in pulmonary vascular smooth muscle following chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 295: L515-L529, 2008
-
(2008)
Am J Physiol Lung Cell Mol Physiol
, vol.295
-
-
Jernigan, N.L.1
Walker, B.R.2
Resta, T.C.3
-
49
-
-
4744347777
-
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta
-
Jin L, Ying Z, and Webb RC. Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta. Am J Physiol Heart Circ Physiol 287: H1495-H1500, 2004
-
(2004)
Am J Physiol Heart Circ Physiol
, vol.287
-
-
Jin, L.1
Ying, Z.2
Webb, R.C.3
-
50
-
-
38849100878
-
Glutathionylation of betaactin via a cysteinyl sulfenic acid intermediary
-
Johansson M and Lundberg M. Glutathionylation of betaactin via a cysteinyl sulfenic acid intermediary. BMC Biochem 8: 26, 2007
-
(2007)
BMC Biochem
, vol.8
, pp. 26
-
-
Johansson, M.1
Lundberg, M.2
-
51
-
-
34247216078
-
Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: A newly recognized mechanism for sustaining ductal constriction
-
Kajimoto H, Hashimoto K, Bonnet SN, Haromy A, Harry G, Moudgil R, Nakanishi T, Rebeyka I, Thebaud B, Michelakis ED, and Archer SL. Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: A newly recognized mechanism for sustaining ductal constriction. Circulation 115: 1777-1788, 2007
-
(2007)
Circulation
, vol.115
, pp. 1777-1788
-
-
Kajimoto, H.1
Hashimoto, K.2
Bonnet, S.N.3
Haromy, A.4
Harry, G.5
Moudgil, R.6
Nakanishi, T.7
Rebeyka, I.8
Thebaud, B.9
Michelakis, E.D.10
Archer, S.L.11
-
52
-
-
80051918956
-
Neuregulin induces HaCaT keratinocyte migration via Rac1-mediated NADPH-oxidase activation
-
Kim JS, Bak EJ, Lee BC, Kim YS, Park JB, and Choi IG. Neuregulin induces HaCaT keratinocyte migration via Rac1-mediated NADPH-oxidase activation. J Cell Physiol 226: 3014-3021, 2011
-
(2011)
J Cell Physiol
, vol.226
, pp. 3014-3021
-
-
Kim, J.S.1
Bak, E.J.2
Lee, B.C.3
Kim, Y.S.4
Park, J.B.5
Choi, I.G.6
-
53
-
-
66349108700
-
Reactive oxygen species regulate a slingshot-cofilin activation pathway
-
Kim JS, Huang TY, and Bokoch GM. Reactive oxygen species regulate a slingshot-cofilin activation pathway. Mol Biol Cell 20: 2650-2660, 2009
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2650-2660
-
-
Kim, J.S.1
Huang, T.Y.2
Bokoch, G.M.3
-
54
-
-
83055161506
-
Rac regulates PtdInsP(3) signaling and the chemotactic compass through a redox-mediated feedback loop
-
Kuiper JW, Sun C, Magalhaes MA, and Glogauer M. Rac regulates PtdInsP(3) signaling and the chemotactic compass through a redox-mediated feedback loop. Blood 118: 6164-6171, 2011
-
(2011)
Blood
, vol.118
, pp. 6164-6171
-
-
Kuiper, J.W.1
Sun, C.2
Magalhaes, M.A.3
Glogauer, M.4
-
55
-
-
1542373753
-
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor
-
Kurokawa K, Itoh RE, Yoshizaki H, Nakamura YO, and Matsuda M. Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. Mol Biol Cell 15: 1003-1010, 2004
-
(2004)
Mol Biol Cell
, vol.15
, pp. 1003-1010
-
-
Kurokawa, K.1
Itoh, R.E.2
Yoshizaki, H.3
Nakamura, Y.O.4
Matsuda, M.5
-
56
-
-
17644371672
-
Perturbation of actin dynamics induces NF-kappaB activation in myelomonocytic cells through an NADPH oxidasedependent pathway
-
Kustermans G, El Benna J, Piette J, and Legrand-Poels S. Perturbation of actin dynamics induces NF-kappaB activation in myelomonocytic cells through an NADPH oxidasedependent pathway. Biochem J 387: 531-540, 2005
-
(2005)
Biochem J
, vol.387
, pp. 531-540
-
-
Kustermans, G.1
El Benna, J.2
Piette, J.3
Legrand-Poels, S.4
-
57
-
-
67749124073
-
Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases
-
Lai FP, Szczodrak M, Oelkers JM, Ladwein M, Acconcia F, Benesch S, Auinger S, Faix J, Small JV, Polo S, Stradal TE, and Rottner K. Cortactin promotes migration and platelet-derived growth factor-induced actin reorganization by signaling to Rho-GTPases. Mol Biol Cell 20: 3209-3223, 2009
-
(2009)
Mol Biol Cell
, vol.20
, pp. 3209-3223
-
-
Lai, F.P.1
Szczodrak, M.2
Oelkers, J.M.3
Ladwein, M.4
Acconcia, F.5
Benesch, S.6
Auinger, S.7
Faix, J.8
Small, J.V.9
Polo, S.10
Stradal, T.E.11
Rottner, K.12
-
58
-
-
1542406446
-
NOX enzymes and the biology of reactive oxygen
-
Lambeth JD. NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol 4: 181-189, 2004
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 181-189
-
-
Lambeth, J.D.1
-
59
-
-
67651096057
-
Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration
-
Lammermann T, Renkawitz J, Wu X, Hirsch K, Brakebusch C, and Sixt M. Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration. Blood 113: 5703-5710, 2009
-
(2009)
Blood
, vol.113
, pp. 5703-5710
-
-
Lammermann, T.1
Renkawitz, J.2
Wu, X.3
Hirsch, K.4
Brakebusch, C.5
Sixt, M.6
-
60
-
-
58049213341
-
Specificity of interactions between mDia isoforms and Rho proteins
-
Lammers M, Meyer S, Kuhlmann D, and Wittinghofer A. Specificity of interactions between mDia isoforms and Rho proteins. J Biol Chem 283: 35236-35246, 2008
-
(2008)
J Biol Chem
, vol.283
, pp. 35236-35246
-
-
Lammers, M.1
Meyer, S.2
Kuhlmann, D.3
Wittinghofer, A.4
-
61
-
-
42049092972
-
Regulation of actin assembly associated with protrusion and adhesion in cell migration
-
Le Clainche C and Carlier MF. Regulation of actin assembly associated with protrusion and adhesion in cell migration. Physiol Rev 88: 489-513, 2008
-
(2008)
Physiol Rev
, vol.88
, pp. 489-513
-
-
Le Clainche, C.1
Carlier, M.F.2
-
62
-
-
33845999557
-
Proteomic profiling and identification of cofilin responding to oxidative stress in vascular smooth muscle
-
Lee CK, Park HJ, So HH, Kim HJ, Lee KS, Choi WS, Lee HM, Won KJ, Yoon TJ, Park TK, and Kim B. Proteomic profiling and identification of cofilin responding to oxidative stress in vascular smooth muscle. Proteomics 6: 6455-6475, 2006
-
(2006)
Proteomics
, vol.6
, pp. 6455-6475
-
-
Lee, C.K.1
Park, H.J.2
So, H.H.3
Kim, H.J.4
Lee, K.S.5
Choi, W.S.6
Lee, H.M.7
Won, K.J.8
Yoon, T.J.9
Park, T.K.10
Kim, B.11
-
63
-
-
77956020315
-
Regulation of actin cytoskeleton dynamics in cells
-
Lee SH and Dominguez R. Regulation of actin cytoskeleton dynamics in cells. Mol Cells 29: 311-325, 2010
-
(2010)
Mol Cells
, vol.29
, pp. 311-325
-
-
Lee, S.H.1
Dominguez, R.2
-
64
-
-
77954394980
-
The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain
-
Leone DP, Srinivasan K, Brakebusch C, and McConnell SK. The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol 70: 659-678, 2010
-
(2010)
Dev Neurobiol
, vol.70
, pp. 659-678
-
-
Leone, D.P.1
Srinivasan, K.2
Brakebusch, C.3
McConnell, S.K.4
-
65
-
-
80054772505
-
Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression
-
Li A, Ma Y, Yu X, Mort RL, Lindsay CR, Stevenson D, Strathdee D, Insall RH, Chernoff J, Snapper SB, Jackson IJ, Larue L, Sansom OJ, and Machesky LM. Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Dev Cell 21: 722-734, 2011
-
(2011)
Dev Cell
, vol.21
, pp. 722-734
-
-
Li, A.1
Ma, Y.2
Yu, X.3
Mort, R.L.4
Lindsay, C.R.5
Stevenson, D.6
Strathdee, D.7
Insall, R.H.8
Chernoff, J.9
Snapper, S.B.10
Jackson, I.J.11
Larue, L.12
Sansom, O.J.13
Machesky, L.M.14
-
66
-
-
0037205457
-
Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells
-
Li JM and Shah AM. Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells. J Biol Chem 277: 19952-19960, 2002
-
(2002)
J Biol Chem
, vol.277
, pp. 19952-19960
-
-
Li, J.M.1
Shah, A.M.2
-
67
-
-
68849112046
-
Cdc42GAP, reactive oxygen species, and the vimentin network
-
Li QF, Spinelli AM, and Tang DD. Cdc42GAP, reactive oxygen species, and the vimentin network. Am J Physiol Cell Physiol 297: C299-C309, 2009
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Li, Q.F.1
Spinelli, A.M.2
Tang, D.D.3
-
68
-
-
73449112677
-
Role of p47(phox) in regulating Cdc42GAP, vimentin, and contraction in smooth muscle cells
-
Li QF and Tang DD. Role of p47(phox) in regulating Cdc42GAP, vimentin, and contraction in smooth muscle cells. Am J Physiol Cell Physiol 297: C1424-C1433, 2009
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Li, Q.F.1
Tang, D.D.2
-
69
-
-
54549102288
-
Beyond polymer polarity: How the cytoskeleton builds a polarized cell
-
Li R and Gundersen GG. Beyond polymer polarity: How the cytoskeleton builds a polarized cell. Nat Rev Mol Cell Biol 9: 860-873, 2008
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 860-873
-
-
Li, R.1
Gundersen, G.G.2
-
70
-
-
65649134364
-
Rac1 expression by fibroblasts is required for tissue repair in vivo
-
Liu S, Kapoor M, and Leask A. Rac1 expression by fibroblasts is required for tissue repair in vivo. Am J Pathol 174: 1847-1856, 2009
-
(2009)
Am J Pathol
, vol.174
, pp. 1847-1856
-
-
Liu, S.1
Kapoor, M.2
Leask, A.3
-
71
-
-
0034769365
-
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells
-
Lommel S, Benesch S, Rottner K, Franz T, Wehland J, and Kuhn R. Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells. EMBO Rep 2: 850-857, 2001
-
(2001)
EMBO Rep
, vol.2
, pp. 850-857
-
-
Lommel, S.1
Benesch, S.2
Rottner, K.3
Franz, T.4
Wehland, J.5
Kuhn, R.6
-
72
-
-
80053906943
-
Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells
-
Maheswaranathan M, Gole HK, Fernandez I, Lassegue B, Griendling KK, and San Martin A. Platelet-derived growth factor (PDGF) regulates Slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. J Biol Chem 286: 35430-35437, 2011
-
(2011)
J Biol Chem
, vol.286
-
-
Maheswaranathan, M.1
Gole, H.K.2
Fernandez, I.3
Lassegue, B.4
Griendling, K.K.5
San Martin, A.6
-
73
-
-
0028078824
-
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
-
Manser E, Leung T, Salihuddin H, Zhao ZS, and Lim L. A brain serine/threonine protein kinase activated by Cdc42 and Rac1. Nature 367: 40-46, 1994
-
(1994)
Nature
, vol.367
, pp. 40-46
-
-
Manser, E.1
Leung, T.2
Salihuddin, H.3
Zhao, Z.S.4
Lim, L.5
-
74
-
-
84878628246
-
Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds
-
Martinelli R, Kamei M, Sage PT, Massol R, Varghese L, Sciuto T, Toporsian M, Dvorak AM, Kirchhausen T, Springer TA, and Carman CV. Release of cellular tension signals self-restorative ventral lamellipodia to heal barrier micro-wounds. J Cell Biol 201: 449-465, 2013
-
(2013)
J Cell Biol
, vol.201
, pp. 449-465
-
-
Martinelli, R.1
Kamei, M.2
Sage, P.T.3
Massol, R.4
Varghese, L.5
Sciuto, T.6
Toporsian, M.7
Dvorak, A.M.8
Kirchhausen, T.9
Springer, T.A.10
Carman, C.V.11
-
75
-
-
77956814772
-
Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse
-
Migeotte I, Omelchenko T, Hall A, and Anderson KV. Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biol 8: E1000442, 2010
-
(2010)
PLoS Biol
, vol.8
-
-
Migeotte, I.1
Omelchenko, T.2
Hall, A.3
Anderson, K.V.4
-
76
-
-
84858218213
-
Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species
-
Miki H and Funato Y. Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species. J Biochem 151: 255-261, 2012
-
(2012)
J Biochem
, vol.151
, pp. 255-261
-
-
Miki, H.1
Funato, Y.2
-
77
-
-
0031952518
-
Induction of filopodium formation by a WASP-related actindepolymerizing protein N-WASP
-
Miki H, Sasaki T, Takai Y, and Takenawa T. Induction of filopodium formation by a WASP-related actindepolymerizing protein N-WASP. Nature 391: 93-96, 1998
-
(1998)
Nature
, vol.391
, pp. 93-96
-
-
Miki, H.1
Sasaki, T.2
Takai, Y.3
Takenawa, T.4
-
78
-
-
0034619847
-
IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling
-
Miki H, Yamaguchi H, Suetsugu S, and Takenawa T. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature 408: 732-735, 2000
-
(2000)
Nature
, vol.408
, pp. 732-735
-
-
Miki, H.1
Yamaguchi, H.2
Suetsugu, S.3
Takenawa, T.4
-
79
-
-
84870673830
-
Redox regulation of Ras and Rho GTPases: Mechanism and function
-
Mitchell L, Hobbs GA, Aghajanian A, and Campbell SL. Redox regulation of Ras and Rho GTPases: Mechanism and function. Antioxid Redox Signal 18: 250-258, 2013
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 250-258
-
-
Mitchell, L.1
Hobbs, G.A.2
Aghajanian, A.3
Campbell, S.L.4
-
80
-
-
0031550240
-
Actin enhances the activation of human neutrophil NADPH oxidase in a cell-free system
-
Morimatsu T, Kawagoshi A, Yoshida K, and Tamura M. Actin enhances the activation of human neutrophil NADPH oxidase in a cell-free system. Biochem Biophys Res Commun 230: 206-210, 1997
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 206-210
-
-
Morimatsu, T.1
Kawagoshi, A.2
Yoshida, K.3
Tamura, M.4
-
81
-
-
84861528238
-
Minimum requirements for the actin-like treadmilling motor system
-
Narita A. Minimum requirements for the actin-like treadmilling motor system. Bioarchitecture 1: 205-208, 2011
-
(2011)
Bioarchitecture
, vol.1
, pp. 205-208
-
-
Narita, A.1
-
82
-
-
0026062962
-
Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components
-
Nauseef WM, Volpp BD, McCormick S, Leidal KG, and Clark RA. Assembly of the neutrophil respiratory burst oxidase. Protein kinase C promotes cytoskeletal and membrane association of cytosolic oxidase components. J Biol Chem 266: 5911-5917, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 5911-5917
-
-
Nauseef, W.M.1
Volpp, B.D.2
McCormick, S.3
Leidal, K.G.4
Clark, R.A.5
-
84
-
-
0034602959
-
Rho-Associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
-
Ohashi K, Nagata K, Maekawa M, Ishizaki T, Narumiya S, and Mizuno K. Rho-Associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop. J Biol Chem 275: 3577-3582, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 3577-3582
-
-
Ohashi, K.1
Nagata, K.2
Maekawa, M.3
Ishizaki, T.4
Narumiya, S.5
Mizuno, K.6
-
85
-
-
84870155534
-
Regulation of collective cell migration by RhoGAP myosin IXA
-
Omelchenko T. Regulation of collective cell migration by RhoGAP myosin IXA. Small GTPases 3: 213-218, 2012
-
(2012)
Small GTPases
, vol.3
, pp. 213-218
-
-
Omelchenko, T.1
-
86
-
-
44449149681
-
Cell responses regulated by early reorganization of actin cytoskeleton
-
Papakonstanti EA and Stournaras C. Cell responses regulated by early reorganization of actin cytoskeleton. FEBS Lett 582: 2120-2127, 2008
-
(2008)
FEBS Lett
, vol.582
, pp. 2120-2127
-
-
Papakonstanti, E.A.1
Stournaras, C.2
-
87
-
-
84863453927
-
Antioxidant dieckol downregulates the Rac1/ROS signaling pathway and inhibits Wiskott-Aldrich syndrome protein (WASP)-family verprolin-homologous protein 2 (WAVE2)-mediated invasive migration of B16 mouse melanoma cells
-
Park SJ, Kim YT, and Jeon YJ. Antioxidant dieckol downregulates the Rac1/ROS signaling pathway and inhibits Wiskott-Aldrich syndrome protein (WASP)-family verprolin-homologous protein 2 (WAVE2)-mediated invasive migration of B16 mouse melanoma cells. Mol Cells 33: 363-369, 2012
-
(2012)
Mol Cells
, vol.33
, pp. 363-369
-
-
Park, S.J.1
Kim, Y.T.2
Jeon, Y.J.3
-
88
-
-
77956459044
-
Rac and Rho GTPases in cancer cell motility control
-
Parri M and Chiarugi P. Rac and Rho GTPases in cancer cell motility control. Cell Commun Signal 8: 23, 2010
-
(2010)
Cell Commun Signal
, vol.8
, pp. 23
-
-
Parri, M.1
Chiarugi, P.2
-
90
-
-
84862876945
-
Rho GTPase function in development: How in vivo models change our view
-
Pedersen E and Brakebusch C. Rho GTPase function in development: How in vivo models change our view. Exp Cell Res 318: 1779-1787, 2012
-
(2012)
Exp Cell Res
, vol.318
, pp. 1779-1787
-
-
Pedersen, E.1
Brakebusch, C.2
-
91
-
-
84875580811
-
At the leading edge of threedimensional cell migration
-
DOI: 10.1002/9780470015902.a0022525
-
Petrie RJ and Yamada KM. At the leading edge of threedimensional cell migration. J Cell Sci 125: 5917-5926, 2012. DOI: 10.1002/9780470015902.a0022525
-
(2012)
J Cell Sci
, vol.125
, pp. 5917-5926
-
-
Petrie, R.J.1
Yamada, K.M.2
-
92
-
-
77951459334
-
Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets
-
Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, Bender M, Wu X, Lanza F, Gachet C, Brakebusch C, and Nieswandt B. Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood 115: 3364-3373, 2010
-
(2010)
Blood
, vol.115
, pp. 3364-3373
-
-
Pleines, I.1
Eckly, A.2
Elvers, M.3
Hagedorn, I.4
Eliautou, S.5
Bender, M.6
Wu, X.7
Lanza, F.8
Gachet, C.9
Brakebusch, C.10
Nieswandt, B.11
-
93
-
-
0037459075
-
Cellular motility driven by assembly and disassembly of actin filaments
-
Pollard TD and Borisy GG. Cellular motility driven by assembly and disassembly of actin filaments. Cell 112: 453-465, 2003
-
(2003)
Cell
, vol.112
, pp. 453-465
-
-
Pollard, T.D.1
Borisy, G.G.2
-
94
-
-
0022555884
-
Actin and actin-binding proteins A critical evaluation of mechanisms and functions
-
Pollard TD and Cooper JA. Actin and actin-binding proteins. A critical evaluation of mechanisms and functions. Annu Rev Biochem 55: 987-1035, 1986
-
(1986)
Annu Rev Biochem
, vol.55
, pp. 987-035
-
-
Pollard, T.D.1
Cooper, J.A.2
-
95
-
-
69549114949
-
WASP and SCAR/WAVE proteins: The drivers of actin assembly
-
Pollitt AY and Insall RH. WASP and SCAR/WAVE proteins: The drivers of actin assembly. J Cell Sci 122: 2575-2578, 2009
-
(2009)
J Cell Sci
, vol.122
, pp. 2575-2578
-
-
Pollitt, A.Y.1
Insall, R.H.2
-
96
-
-
33745804975
-
The expanding role of NADPH oxidases in health and disease: No longer just agents of death and destruction
-
Quinn MT, Ammons MC, and Deleo FR. The expanding role of NADPH oxidases in health and disease: No longer just agents of death and destruction. Clin Sci (Lond) 111: 1-20, 2006
-
(2006)
Clin Sci (Lond
, vol.111
, pp. 1-20
-
-
Quinn, M.T.1
Ammons, M.C.2
Deleo, F.R.3
-
97
-
-
34250778409
-
Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases
-
Raines KW, Bonini MG, and Campbell SL. Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases. Cardiovasc Res 75: 229-239, 2007
-
(2007)
Cardiovasc Res
, vol.75
, pp. 229-239
-
-
Raines, K.W.1
Bonini, M.G.2
Campbell, S.L.3
-
98
-
-
33748994545
-
Rho gtPases and actin dynamics in membrane protrusions and vesicle trafficking
-
Ridley AJ. Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 16: 522-529, 2006
-
(2006)
Trends Cell Biol
, vol.16
, pp. 522-529
-
-
Ridley, A.J.1
-
99
-
-
79959677602
-
Life at the leading edge
-
Ridley AJ. Life at the leading edge. Cell 145: 1012-1022, 2011
-
(2011)
Cell
, vol.145
, pp. 1012-1022
-
-
Ridley, A.J.1
-
100
-
-
0024315423
-
Morphogenesis of the polarized epithelial cell phenotype
-
Rodriguez-Boulan E and Nelson WJ. Morphogenesis of the polarized epithelial cell phenotype. Science 245: 718-725, 1989
-
(1989)
Science
, vol.245
, pp. 718-725
-
-
Rodriguez-Boulan, E.1
Nelson, W.J.2
-
101
-
-
79959340042
-
Protein sulfenic acid formation: From cellular damage to redox regulation
-
Roos G and Messens J. Protein sulfenic acid formation: From cellular damage to redox regulation. Free Radic Biol Med 51: 314-326, 2011
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 314-326
-
-
Roos, G.1
Messens, J.2
-
102
-
-
80053328974
-
Actin dynamics and turnover in cell motility
-
Rottner K and Stradal TE. Actin dynamics and turnover in cell motility. Curr Opin Cell Biol 23: 569-578, 2011
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 569-578
-
-
Rottner, K.1
Stradal, T.E.2
-
103
-
-
38049078282
-
The structural basis of actin filament branching by the Arp2/3 complex
-
Rouiller I, Xu XP, Amann KJ, Egile C, Nickell S, Nicastro D, Li R, Pollard TD, Volkmann N, and Hanein D. The structural basis of actin filament branching by the Arp2/3 complex. J Cell Biol 180: 887-895, 2008
-
(2008)
J Cell Biol
, vol.180
, pp. 887-895
-
-
Rouiller, I.1
Xu, X.P.2
Amann, K.J.3
Egile, C.4
Nickell, S.5
Nicastro, D.6
Li, R.7
Pollard, T.D.8
Volkmann, N.9
Hanein, D.10
-
104
-
-
67650073105
-
NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/ alpha3 integrins
-
Sadok A, Pierres A, Dahan L, Prevot C, Lehmann M, and Kovacic H. NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of alpha2/ alpha3 integrins. Mol Cell Biol 29: 3915-3928, 2009
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3915-3928
-
-
Sadok, A.1
Pierres, A.2
Dahan, L.3
Prevot, C.4
Lehmann, M.5
Kovacic, H.6
-
105
-
-
0042354574
-
Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis
-
Sahai E and Marshall CJ. Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis. Nat Cell Biol 5: 711-719, 2003
-
(2003)
Nat Cell Biol
, vol.5
, pp. 711-719
-
-
Sahai, E.1
Marshall, C.J.2
-
106
-
-
84870878170
-
Reactive oxygen speciesinduced actin glutathionylation controls actin dynamics in neutrophils
-
Sakai J, Li J, Subramanian KK, Mondal S, Bajrami B, Hattori H, Jia Y, Dickinson BC, Zhong J, Ye K, Chang CJ, Ho YS, Zhou J, and Luo HR. Reactive oxygen speciesinduced actin glutathionylation controls actin dynamics in neutrophils. Immunity 37: 1037-1049, 2012
-
(2012)
Immunity
, vol.37
, pp. 1037-1049
-
-
Sakai, J.1
Li, J.2
Subramanian, K.K.3
Mondal, S.4
Bajrami, B.5
Hattori, H.6
Jia, Y.7
Dickinson, B.C.8
Zhong, J.9
Ye, K.10
Chang, C.J.11
Ho, Y.S.12
Zhou, J.13
Luo, H.R.14
-
107
-
-
76249110094
-
Redox control of vascular smooth muscle migration
-
San Martin A and Griendling KK. Redox control of vascular smooth muscle migration. Antioxid Redox Signal 12: 625-640, 2010
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 625-640
-
-
San Martin, A.1
Griendling, K.K.2
-
108
-
-
41549124089
-
WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells
-
Sarmiento C, Wang W, Dovas A, Yamaguchi H, Sidani M, El-Sibai M, Desmarais V, Holman HA, Kitchen S, Backer JM, Alberts A, and Condeelis J. WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells. J Cell Biol 180: 1245-1260, 2008
-
(2008)
J Cell Biol
, vol.180
, pp. 1245-1260
-
-
Sarmiento, C.1
Wang, W.2
Dovas, A.3
Yamaguchi, H.4
Sidani, M.5
El-Sibai, M.6
Desmarais, V.7
Holman, H.A.8
Kitchen, S.9
Backer, J.M.10
Alberts, A.11
Condeelis, J.12
-
109
-
-
84898413435
-
NADPH oxidases in redox regulation of cell adhesion and migration
-
Schröder K. NADPH oxidases in redox regulation of cell adhesion and migration. Antioxid Redox Signal 20: 2043-2058, 2014
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 2043-2058
-
-
Schröder, K.1
-
110
-
-
50649106845
-
Unravelling the structure of the lamellipodium
-
Small JV, Auinger S, Nemethova M, Koestler S, Goldie KN, Hoenger A, and Resch GP. Unravelling the structure of the lamellipodium. J Microsc 231: 479-485, 2008
-
(2008)
J Microsc
, vol.231
, pp. 479-485
-
-
Small, J.V.1
Auinger, S.2
Nemethova, M.3
Koestler, S.4
Goldie, K.N.5
Hoenger, A.6
Resch, G.P.7
-
111
-
-
0034795423
-
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actinbased motility
-
Snapper SB, Takeshima F, Anton I, Liu CH, Thomas SM, Nguyen D, Dudley D, Fraser H, Purich D, Lopez-Ilasaca M, Klein C, Davidson L, Bronson R, Mulligan RC, Southwick F, Geha R, Goldberg MB, Rosen FS, Hartwig JH, and Alt FW. N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actinbased motility. Nat Cell Biol 3: 897-904, 2001
-
(2001)
Nat Cell Biol
, vol.3
, pp. 897-904
-
-
Snapper, S.B.1
Takeshima, F.2
Anton, I.3
Liu, C.H.4
Thomas, S.M.5
Nguyen, D.6
Dudley, D.7
Fraser, H.8
Purich, D.9
Lopez-Ilasaca, M.10
Klein, C.11
Davidson, L.12
Bronson, R.13
Mulligan, R.C.14
Southwick, F.15
Geha, R.16
Goldberg, M.B.17
Rosen, F.S.18
Hartwig, J.H.19
Alt, F.W.20
more..
-
112
-
-
79952352658
-
Dynamics of the Rho-family small GTPases in actin regulation and motility
-
Spiering D and Hodgson L. Dynamics of the Rho-family small GTPases in actin regulation and motility. Cell Adh Migr 5: 170-180, 2011
-
(2011)
Cell Adh Migr
, vol.5
, pp. 170-180
-
-
Spiering, D.1
Hodgson, L.2
-
113
-
-
84869434980
-
Rho gtpases and nox dependent ros production in skin is there a connection?
-
Stanley A, Hynes A, Brakebusch C, and Quondamatteo F. Rho GTPases and Nox dependent ROS production in skin. Is there a connection?. Histol Histopathol 27: 1395-1406, 2012
-
(2012)
Histol Histopathol
, vol.27
, pp. 1395-1406
-
-
Stanley, A.1
Hynes, A.2
Brakebusch, C.3
Quondamatteo, F.4
-
114
-
-
0033600187
-
Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex
-
Suetsugu S, Miki H, and Takenawa T. Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex. Biochem Biophys Res Commun 260: 296-302, 1999
-
(1999)
Biochem Biophys Res Commun
, vol.260
, pp. 296-302
-
-
Suetsugu, S.1
Miki, H.2
Takenawa, T.3
-
115
-
-
0033620689
-
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia
-
Svitkina TM and Borisy GG. Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol 145: 1009-1026, 1999
-
(1999)
J Cell Biol
, vol.145
, pp. 1009-1026
-
-
Svitkina, T.M.1
Borisy, G.G.2
-
116
-
-
0030006284
-
Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
-
Symons M, Derry JM, Karlak B, Jiang S, Lemahieu V, McCormick F, Francke U, and Abo A. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell 84: 723-734, 1996
-
(1996)
Cell
, vol.84
, pp. 723-734
-
-
Symons, M.1
Derry, J.M.2
Karlak, B.3
Jiang, S.4
Lemahieu, V.5
McCormick, F.6
Francke, U.7
Abo, A.8
-
117
-
-
77952602705
-
Rac1 regulates neuronal polarization through the WAVE complex
-
Tahirovic S, Hellal F, Neukirchen D, Hindges R, Garvalov BK, Flynn KC, Stradal TE, Chrostek-Grashoff A, Brakebusch C, and Bradke F. Rac1 regulates neuronal polarization through the WAVE complex. J Neurosci 30: 6930-6943, 2010
-
(2010)
J Neurosci
, vol.30
, pp. 6930-6943
-
-
Tahirovic, S.1
Hellal, F.2
Neukirchen, D.3
Hindges, R.4
Garvalov, B.K.5
Flynn, K.C.6
Stradal, T.E.7
Chrostek-Grashoff, A.8
Brakebusch, C.9
Bradke, F.10
-
118
-
-
29344447062
-
Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase
-
Tamura M, Itoh K, Akita H, Takano K, and Oku S. Identification of an actin-binding site in p47phox an organizer protein of NADPH oxidase. FEBS Lett 580: 261-267, 2006
-
(2006)
FEBS Lett
, vol.580
, pp. 261-267
-
-
Tamura, M.1
Itoh, K.2
Akita, H.3
Takano, K.4
Oku, S.5
-
119
-
-
0034609962
-
Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase
-
Tamura M, Kai T, Tsunawaki S, Lambeth JD, and Kameda K. Direct interaction of actin with p47(phox) of neutrophil NADPH oxidase. Biochem Biophys Res Commun 276: 1186-1190, 2000
-
(2000)
Biochem Biophys Res Commun
, vol.276
, pp. 1186-1190
-
-
Tamura, M.1
Kai, T.2
Tsunawaki, S.3
Lambeth, J.D.4
Kameda, K.5
-
120
-
-
84873731427
-
Post-Translational modification and regulation of actin
-
Terman JR and Kashina A. Post-Translational modification and regulation of actin. Curr Opin Cell Biol 25: 30-38, 2013
-
(2013)
Curr Opin Cell Biol
, vol.25
, pp. 30-38
-
-
Terman, J.R.1
Kashina, A.2
-
121
-
-
84867886120
-
Cadherins in collective cell migration of mesenchymal cells
-
Theveneau E and Mayor R. Cadherins in collective cell migration of mesenchymal cells. Curr Opin Cell Biol 24: 677-684, 2012
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 677-684
-
-
Theveneau, E.1
Mayor, R.2
-
122
-
-
14644404356
-
P47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: Role in NAD(P)H oxidase regulation by angiotensin II
-
Touyz RM, Yao G, Quinn MT, Pagano PJ, and Schiffrin EL. p47phox associates with the cytoskeleton through cortactin in human vascular smooth muscle cells: Role in NAD(P)H oxidase regulation by angiotensin II. Arterioscler Thromb Vasc Biol 25: 512-518, 2005
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 512-518
-
-
Touyz, R.M.1
Yao, G.2
Quinn, M.T.3
Pagano, P.J.4
Schiffrin, E.L.5
-
123
-
-
34249097854
-
Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1
-
Tscharntke M, Pofahl R, Chrostek-Grashoff A, Smyth N, Niessen C, Niemann C, Hartwig B, Herzog V, Klein HW, Krieg T, Brakebusch C, and Haase I. Impaired epidermal wound healing in vivo upon inhibition or deletion of Rac1. J Cell Sci 120: 1480-1490, 2007
-
(2007)
J Cell Sci
, vol.120
, pp. 1480-1490
-
-
Tscharntke, M.1
Pofahl, R.2
Chrostek-Grashoff, A.3
Smyth, N.4
Niessen, C.5
Niemann, C.6
Hartwig, B.7
Herzog, V.8
Klein, H.W.9
Krieg, T.10
Brakebusch, C.11
Haase, I.12
-
124
-
-
0038348531
-
HIF-1alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma
-
Turcotte S, Desrosiers RR, and Beliveau R. HIF-1alpha mRNA and protein upregulation involves Rho GTPase expression during hypoxia in renal cell carcinoma. J Cell Sci 116: 2247-2260, 2003
-
(2003)
J Cell Sci
, vol.116
, pp. 2247-2260
-
-
Turcotte, S.1
Desrosiers, R.R.2
Beliveau, R.3
-
125
-
-
34548168822
-
Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin
-
Usatyuk PV, Romer LH, He D, Parinandi NL, Kleinberg ME, Zhan S, Jacobson JR, Dudek SM, Pendyala S, Garcia JG, and Natarajan V. Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin. J Biol Chem 282: 23284-23295, 2007
-
(2007)
J Biol Chem
, vol.282
, pp. 23284-23295
-
-
Usatyuk, P.V.1
Romer, L.H.2
He, D.3
Parinandi, N.L.4
Kleinberg, M.E.5
Zhan, S.6
Jacobson, J.R.7
Dudek, S.M.8
Pendyala, S.9
Garcia, J.G.10
Natarajan, V.11
-
126
-
-
33749047437
-
Localizing NADPH oxidase-derived ROS
-
Ushio-Fukai M. Localizing NADPH oxidase-derived ROS. Sci STKE 2006: Re8, 2006
-
(2006)
Sci STKE
, vol.2006
, pp. 8
-
-
Ushio-Fukai, M.1
-
127
-
-
65349157681
-
Compartmentalization of redox signaling through NADPH oxidase-derived ROS
-
Ushio-Fukai M. Compartmentalization of redox signaling through NADPH oxidase-derived ROS. Antioxid Redox Signal 11: 1289-1299, 2009
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 1289-1299
-
-
Ushio-Fukai, M.1
-
128
-
-
1542365175
-
Continuous translocation of Rac2 and the NADPH oxidase component p67(phox) during phagocytosis
-
van Bruggen R, Anthony E, Fernandez-Borja M, and Roos D. Continuous translocation of Rac2 and the NADPH oxidase component p67(phox) during phagocytosis. J Biol Chem 279: 9097-9102, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 9097-9102
-
-
Van Bruggen, R.1
Anthony, E.2
Fernandez-Borja, M.3
Roos, D.4
-
129
-
-
49049101658
-
Ins and outs of ADF/cofilin activity and regulation
-
Van Troys M, Huyck L, Leyman S, Dhaese S, Vandekerkhove J, and Ampe C. Ins and outs of ADF/cofilin activity and regulation. Eur J Cell Biol 87: 649-667, 2008
-
(2008)
Eur J Cell Biol
, vol.87
, pp. 649-667
-
-
Van Troys, M.1
Huyck, L.2
Leyman, S.3
Dhaese, S.4
Vandekerkhove, J.5
Ampe, C.6
-
130
-
-
0035930608
-
Reversible glutathionylation regulates actin polymerization in A431 cells
-
Wang J, Boja ES, Tan W, Tekle E, Fales HM, English S, Mieyal JJ, and Chock PB. Reversible glutathionylation regulates actin polymerization in A431 cells. J Biol Chem276: 47763-47766, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 47763-47766
-
-
Wang, J.1
Boja, E.S.2
Tan, W.3
Tekle, E.4
Fales, H.M.5
English, S.6
Mieyal, J.J.7
Chock, P.B.8
-
131
-
-
84865972972
-
Regulation of the actin cytoskeleton in Helicobacter pylori-induced migration and invasive growth of gastric epithelial cells
-
Wessler S, Gimona M, and Rieder G. Regulation of the actin cytoskeleton in Helicobacter pylori-induced migration and invasive growth of gastric epithelial cells. Cell Commun Signal 9: 27, 2011
-
(2011)
Cell Commun Signal
, vol.9
, pp. 27
-
-
Wessler, S.1
Gimona, M.2
Rieder, G.3
-
132
-
-
15544387084
-
Rac and Rho play opposing roles in the regulation of hypoxia/ reoxygenation-induced permeability changes in pulmonary artery endothelial cells
-
Wojciak-Stothard B, Tsang LY, and Haworth SG. Rac and Rho play opposing roles in the regulation of hypoxia/reoxygenation-induced permeability changes in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 288: L749-L760, 2005
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Wojciak-Stothard, B.1
Tsang, L.Y.2
Haworth, S.G.3
-
133
-
-
0025763670
-
Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils
-
Woodman RC, Ruedi JM, Jesaitis AJ, Okamura N, Quinn MT, and Smith RM, Curnutte JT, Babior BM. Respiratory burst oxidase and three of four oxidase-related polypeptides are associated with the cytoskeleton of human neutrophils. J Clin Invest 87: 1345-1351, 1991
-
(1991)
J Clin Invest
, vol.87
, pp. 1345-1351
-
-
Woodman, R.C.1
Ruedi, J.M.2
Jesaitis, A.J.3
Okamura, N.4
Quinn, M.T.5
Smith, R.M.6
Curnutte, J.T.7
Babior, B.M.8
-
134
-
-
0141703529
-
Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1
-
Wu RF, Gu Y, Xu YC, Nwariaku FE, and Terada LS. Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1. J Biol Chem 278: 36830-36840, 2003
-
(2003)
J Biol Chem
, vol.278
, pp. 36830-36840
-
-
Wu, R.F.1
Gu, Y.2
Xu, Y.C.3
Nwariaku, F.E.4
Terada, L.S.5
-
135
-
-
80053458405
-
Filopodia initiation: Focus on the Arp2/3 complex and formins
-
Yang C and Svitkina T. Filopodia initiation: Focus on the Arp2/3 complex and formins. Cell Adh Migr 5: 402-408, 2011
-
(2011)
Cell Adh Migr
, vol.5
, pp. 402-408
-
-
Yang, C.1
Svitkina, T.2
-
136
-
-
33750493895
-
Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts
-
Yang L, Wang L, and Zheng Y. Gene targeting of Cdc42 and Cdc42GAP affirms the critical involvement of Cdc42 in filopodia induction, directed migration, and proliferation in primary mouse embryonic fibroblasts. Mol Biol Cell 17: 4675-4685, 2006
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4675-4685
-
-
Yang, L.1
Wang, L.2
Zheng, Y.3
-
137
-
-
56149118852
-
Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells
-
Zaoui K, Honore S, Isnardon D, Braguer D, and Badache A. Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells. J Cell Biol 183: 401-408, 2008
-
(2008)
J Cell Biol
, vol.183
, pp. 401-408
-
-
Zaoui, K.1
Honore, S.2
Isnardon, D.3
Braguer, D.4
Badache, A.5
-
138
-
-
15944396277
-
P47(phox) X domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton
-
Zhan Y, He D, Newburger PE, and Zhou GW. p47(phox) X domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton. J Cell Biochem 92: 795-809, 2004.
-
(2004)
J Cell Biochem
, vol.92
, pp. 795-809
-
-
Zhan, Y.1
He, D.2
Newburger, P.E.3
Zhou, G.W.4
|