-
1
-
-
34547691071
-
The role of GSK3 in glucose homeostasis and the development of insulin resistance
-
Lee J, Kim MS. The role of GSK3 in glucose homeostasis and the development of insulin resistance. Diabetes Res Clin Pract 2007; 77(Suppl 1): S49-S57
-
(2007)
Diabetes Res Clin Pract
, vol.77
, Issue.SUPPL. . 1
-
-
Lee, J.1
Kim, M.S.2
-
2
-
-
77954874401
-
GSK3 signalling in neural development
-
Hur EM, Zhou FQ. GSK3 signalling in neural development. Nat Rev Neurosci 2010; 11: 539-551
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 539-551
-
-
Hur, E.M.1
Zhou, F.Q.2
-
3
-
-
57349143530
-
Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
-
Luo J. Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett 2009; 273: 194-200
-
(2009)
Cancer Lett
, vol.273
, pp. 194-200
-
-
Luo, J.1
-
4
-
-
54549120290
-
Glycogen synthase kinase-3 and cancer: Good cop, bad cop
-
Patel S, Woodgett J. Glycogen synthase kinase-3 and cancer: Good cop, bad cop? Cancer Cell 2008; 14: 351-353
-
(2008)
Cancer Cell
, vol.14
, pp. 351-353
-
-
Patel, S.1
Woodgett, J.2
-
5
-
-
0036190970
-
Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways
-
Manoukian AS, Woodgett JR. Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways. Adv Cancer Res 2002; 84: 203-229
-
(2002)
Adv Cancer Res
, vol.84
, pp. 203-229
-
-
Manoukian, A.S.1
Woodgett, J.R.2
-
6
-
-
73349140832
-
An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3beta
-
Miyashita K, Nakada M, Shakoori A, Ishigaki Y, Shimasaki T, Motoo Y, et al. An emerging strategy for cancer treatment targeting aberrant glycogen synthase kinase 3beta. Anticancer Agents Med Chem 2009; 9: 1114-1122
-
(2009)
Anticancer Agents Med Chem
, vol.9
, pp. 1114-1122
-
-
Miyashita, K.1
Nakada, M.2
Shakoori, A.3
Ishigaki, Y.4
Shimasaki, T.5
Motoo, Y.6
-
7
-
-
77953233857
-
GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis
-
Wang Z, Iwasaki M, Ficara F, Lin C, Matheny C, Wong SH, et al. GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis. Cancer Cell 2010; 17: 597-608
-
(2010)
Cancer Cell
, vol.17
, pp. 597-608
-
-
Wang, Z.1
Iwasaki, M.2
Ficara, F.3
Lin, C.4
Matheny, C.5
Wong, S.H.6
-
8
-
-
55249120170
-
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
-
Wang Z, Smith KS, Murphy M, Piloto O, Somervaille TC, Cleary ML. Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy. Nature 2008; 455: 1205-1209
-
(2008)
Nature
, vol.455
, pp. 1205-1209
-
-
Wang, Z.1
Smith, K.S.2
Murphy, M.3
Piloto, O.4
Somervaille, T.C.5
Cleary, M.L.6
-
9
-
-
82755187773
-
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation
-
Shin S, Wolgamott L, Yu Y, Blenis J, Yoon SO. Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation. Proc Natl Acad Sci USA 2011; 108: E1204-E1213
-
(2011)
Proc Natl Acad Sci USA
, vol.108
-
-
Shin, S.1
Wolgamott, L.2
Yu, Y.3
Blenis, J.4
Yoon, S.O.5
-
10
-
-
34547114509
-
Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
-
Ougolkov AV, Bone ND, Fernandez-Zapico ME, Kay NE, Billadeau DD. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 2007; 110: 735-742
-
(2007)
Blood
, vol.110
, pp. 735-742
-
-
Ougolkov, A.V.1
Bone, N.D.2
Fernandez-Zapico, M.E.3
Kay, N.E.4
Billadeau, D.D.5
-
11
-
-
0034612636
-
Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
-
Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000; 406: 86-90
-
(2000)
Nature
, vol.406
, pp. 86-90
-
-
Hoeflich, K.P.1
Luo, J.2
Rubie, E.A.3
Tsao, M.S.4
Jin, O.5
Woodgett, J.R.6
-
12
-
-
0037172661
-
Glycogen synthase kinase-3beta modulates notch signaling and stability
-
Foltz DR, Santiago MC, Berechid BE, Nye JS. Glycogen synthase kinase-3beta modulates notch signaling and stability. Curr Biol 2002; 12: 1006-1011
-
(2002)
Curr Biol
, vol.12
, pp. 1006-1011
-
-
Foltz, D.R.1
Santiago, M.C.2
Berechid, B.E.3
Nye, J.S.4
-
13
-
-
10744232627
-
Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta
-
Qu L, Huang S, Baltzis D, Rivas-Estilla AM, Pluquet O, Hatzoglou M, et al. Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta. Genes Dev 2004; 18: 261-277
-
(2004)
Genes Dev
, vol.18
, pp. 261-277
-
-
Qu, L.1
Huang, S.2
Baltzis, D.3
Rivas-Estilla, A.M.4
Pluquet, O.5
Hatzoglou, M.6
-
14
-
-
36249022250
-
GSK-3-mediated phosphorylation enhances Maf-Transforming activity
-
Rocques N, Abou Zeid N, Sii-Felice K, Lecoin L, Felder-Schmittbuhl MP, Eychene A, et al. GSK-3-mediated phosphorylation enhances Maf-Transforming activity. Mol Cell 2007; 28: 584-597
-
(2007)
Mol Cell
, vol.28
, pp. 584-597
-
-
Rocques, N.1
Abou Zeid, N.2
Sii-Felice, K.3
Lecoin, L.4
Felder-Schmittbuhl, M.P.5
Eychene, A.6
-
15
-
-
80755132133
-
Kinome siRNAphosphoproteomic screen identifies networks regulating AKT signaling
-
Lu Y, Muller M, Smith D, Dutta B, Komurov K, Iadevaia S, et al. Kinome siRNAphosphoproteomic screen identifies networks regulating AKT signaling. Oncogene 2011; 30: 4567-4577
-
(2011)
Oncogene
, vol.30
, pp. 4567-4577
-
-
Lu, Y.1
Muller, M.2
Smith, D.3
Dutta, B.4
Komurov, K.5
Iadevaia, S.6
-
16
-
-
33646795341
-
Targeting gsk-3 a promising approach for cancer therapy
-
Ougolkov AV, Billadeau DD. Targeting GSK-3: A promising approach for cancer therapy? Future Oncol 2006; 2: 91-100
-
(2006)
Future Oncol
, vol.2
, pp. 91-100
-
-
Ougolkov, A.V.1
Billadeau, D.D.2
-
17
-
-
80051592124
-
Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells
-
Liu T, Yacoub R, Taliaferro-Smith LD, Sun SY, Graham TR, Dolan R, et al. Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells. Mol Cancer Ther 2011; 10: 1460-1469
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1460-1469
-
-
Liu, T.1
Yacoub, R.2
Taliaferro-Smith, L.D.3
Sun, S.Y.4
Graham, T.R.5
Dolan, R.6
-
18
-
-
77949659245
-
Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: An in vivo bioluminescence imaging study
-
Zeng Q, Yang Z, Gao YJ, Yuan H, Cui K, Shi Y, et al. Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: An in vivo bioluminescence imaging study. Eur J Cancer 2010; 46: 1132-1143
-
(2010)
Eur J Cancer
, vol.46
, pp. 1132-1143
-
-
Zeng, Q.1
Yang, Z.2
Gao, Y.J.3
Yuan, H.4
Cui, K.5
Shi, Y.6
-
19
-
-
79955637310
-
The biological and therapeutic relevance of mRNA translation in cancer
-
Blagden SP, Willis AE. The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol 2011; 8: 280-291
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 280-291
-
-
Blagden, S.P.1
Willis, A.E.2
-
20
-
-
57149118433
-
A protein that replaces the entire cellular eIF4F complex
-
Mir MA, Panganiban AT. A protein that replaces the entire cellular eIF4F complex. EMBO J 2008; 27: 3129-3139
-
(2008)
EMBO J
, vol.27
, pp. 3129-3139
-
-
Mir, M.A.1
Panganiban, A.T.2
-
21
-
-
0033153166
-
Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism
-
Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, et al. Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism. Genes Dev 1999; 13: 1422-1437
-
(1999)
Genes Dev
, vol.13
, pp. 1422-1437
-
-
Gingras, A.C.1
Gygi, S.P.2
Raught, B.3
Polakiewicz, R.D.4
Abraham, R.T.5
Hoekstra, M.F.6
-
22
-
-
78049381472
-
New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress
-
Ayuso MI, Hernandez-Jimenez M, Martin ME, Salinas M, Alcazar A. New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress. J Biol Chem 2010; 285: 34355-34363
-
(2010)
J Biol Chem
, vol.285
, pp. 34355-34363
-
-
Ayuso, M.I.1
Hernandez-Jimenez, M.2
Martin, M.E.3
Salinas, M.4
Alcazar, A.5
-
23
-
-
38449110890
-
Methods for studying signal-dependent regulation of translation factor activity
-
Wang X, Proud CG. Methods for studying signal-dependent regulation of translation factor activity. Methods Enzymol 2007; 431: 113-142
-
(2007)
Methods Enzymol
, vol.431
, pp. 113-142
-
-
Wang, X.1
Proud, C.G.2
-
24
-
-
0035498939
-
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
-
Gingras AC, Raught B, Gygi SP, Niedzwiecka A, Miron M, Burley SK, et al. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes Dev 2001; 15: 2852-2864
-
(2001)
Genes Dev
, vol.15
, pp. 2852-2864
-
-
Gingras, A.C.1
Raught, B.2
Gygi, S.P.3
Niedzwiecka, A.4
Miron, M.5
Burley, S.K.6
-
25
-
-
0037373346
-
The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation
-
Wang X, Li W, Parra JL, Beugnet A, Proud CG. The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation. Mol Cell Biol 2003; 23: 1546-1557
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1546-1557
-
-
Wang, X.1
Li, W.2
Parra, J.L.3
Beugnet, A.4
Proud, C.G.5
-
26
-
-
80052899298
-
A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells
-
Tullai JW, Graham JR, Cooper GM. A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells. Cell Cycle 2011; 10: 3072-3077
-
(2011)
Cell Cycle
, vol.10
, pp. 3072-3077
-
-
Tullai, J.W.1
Graham, J.R.2
Cooper, G.M.3
-
27
-
-
0037205315
-
Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development
-
Hardt SE, Sadoshima J. Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development. Circ Res 2002; 90: 1055-1063
-
(2002)
Circ Res
, vol.90
, pp. 1055-1063
-
-
Hardt, S.E.1
Sadoshima, J.2
-
28
-
-
0036090823
-
Glycogen synthase kinase 3: An emerging therapeutic target
-
Eldar-Finkelman H. Glycogen synthase kinase 3: An emerging therapeutic target. Trends Mol Med 2002; 8: 126-132
-
(2002)
Trends Mol Med
, vol.8
, pp. 126-132
-
-
Eldar-Finkelman, H.1
-
29
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-Tasking kinase
-
Doble BW, Woodgett JR. GSK-3: Tricks of the trade for a multi-Tasking kinase. J Cell Sci 2003; 116: 1175-1186
-
(2003)
J Cell Sci
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
30
-
-
79958696336
-
Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
-
Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villen J, et al. Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 2011; 332: 1322-1326
-
(2011)
Science
, vol.332
, pp. 1322-1326
-
-
Yu, Y.1
Yoon, S.O.2
Poulogiannis, G.3
Yang, Q.4
Ma, X.M.5
Villen, J.6
-
31
-
-
80555129351
-
Oncogenic and tumor suppressor functions of notch in cancer: It's notch what you think
-
Lobry C, Oh P, Aifantis I. Oncogenic and tumor suppressor functions of Notch in cancer: It's NOTCH what you think. J Exp Med 2011; 208: 1931-1935
-
(2011)
J Exp Med
, vol.208
, pp. 1931-1935
-
-
Lobry, C.1
Oh, P.2
Aifantis, I.3
-
32
-
-
79957562024
-
No paradox, no progress: Inverse cancer comorbidity in people with other complex diseases
-
Tabares-Seisdedos R, Dumont N, Baudot A, Valderas JM, Climent J, Valencia A, et al. No paradox, no progress: Inverse cancer comorbidity in people with other complex diseases. Lancet Oncol 2011; 12: 604-608
-
(2011)
Lancet Oncol
, vol.12
, pp. 604-608
-
-
Tabares-Seisdedos, R.1
Dumont, N.2
Baudot, A.3
Valderas, J.M.4
Climent, J.5
Valencia, A.6
-
33
-
-
58049192725
-
Long-Term all-cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta-Analysis
-
Barone BB, Yeh HC, Snyder CF, Peairs KS, Stein KB, Derr RL, et al. Long-Term all-cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta-Analysis. JAMA 2008; 300: 2754-2764
-
(2008)
JAMA
, vol.300
, pp. 2754-2764
-
-
Barone, B.B.1
Yeh, H.C.2
Snyder, C.F.3
Peairs, K.S.4
Stein, K.B.5
Derr, R.L.6
-
34
-
-
13344270279
-
Diabetes mellitus and breast cancer
-
Wolf I, Sadetzki S, Catane R, Karasik A, Kaufman B. Diabetes mellitus and breast cancer. Lancet Oncol 2005; 6: 103-111
-
(2005)
Lancet Oncol
, vol.6
, pp. 103-111
-
-
Wolf, I.1
Sadetzki, S.2
Catane, R.3
Karasik, A.4
Kaufman, B.5
-
35
-
-
77953262873
-
Glycogen synthase kinase-3 and leukemia: Restoring the balance
-
Birch NW, Zeleznik-Le NJ. Glycogen synthase kinase-3 and leukemia: Restoring the balance. Cancer Cell 2010; 17: 529-531
-
(2010)
Cancer Cell
, vol.17
, pp. 529-531
-
-
Birch, N.W.1
Zeleznik-Le, N.J.2
-
36
-
-
4544220704
-
Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 2004; 431: 200-205
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
Picard, F.4
Joaquin, M.5
Sticker, M.6
-
37
-
-
0035815669
-
Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver
-
Jiang YP, Ballou LM, Lin RZ. Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver. J Biol Chem 2001; 276: 10943-10951
-
(2001)
J Biol Chem
, vol.276
, pp. 10943-10951
-
-
Jiang, Y.P.1
Ballou, L.M.2
Lin, R.Z.3
-
38
-
-
56249147509
-
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-Type-specific repression of mRNA translation
-
Choo AY, Yoon SO, Kim SG, Roux PP, Blenis J. Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-Type-specific repression of mRNA translation. Proc Natl Acad Sci USA 2008; 105: 17414-17419
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17414-17419
-
-
Choo, A.Y.1
Yoon, S.O.2
Kim, S.G.3
Roux, P.P.4
Blenis, J.5
-
39
-
-
84863116501
-
Mtor-independent 4e-bp1 phosphorylation is associated with cancer resistance to mtor kinase inhibitors
-
Zhang Y, Zheng XF. mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors. Cell Cycle 2012; 11: 594-603
-
(2012)
Cell Cycle
, vol.11
, pp. 594-603
-
-
Zhang, Y.1
Zheng, X.F.2
-
40
-
-
77649286736
-
Genetic dissection of the oncogenic mtor pathway reveals druggable addiction to translational control via 4ebp-eif4e
-
Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, et al. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell 2010; 17: 249-261
-
(2010)
Cancer Cell
, vol.17
, pp. 249-261
-
-
Hsieh, A.C.1
Costa, M.2
Zollo, O.3
Davis, C.4
Feldman, M.E.5
Testa, J.R.6
-
41
-
-
80052592002
-
A directed protein interaction network for investigating intracellular signal transduction
-
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, et al. A directed protein interaction network for investigating intracellular signal transduction. Sci Signal 2011; 4: Rs8
-
(2011)
Sci Signal
, vol.4
-
-
Vinayagam, A.1
Stelzl, U.2
Foulle, R.3
Plassmann, S.4
Zenkner, M.5
Timm, J.6
-
43
-
-
77951231349
-
MTOR and cancer: Many loops in one pathway
-
Efeyan A, Sabatini DM. mTOR and cancer: Many loops in one pathway. Curr Opin Cell Biol 2010; 22: 169-176
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 169-176
-
-
Efeyan, A.1
Sabatini, D.M.2
-
44
-
-
0037043851
-
P53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation
-
Horton LE, Bushell M, Barth-Baus D, Tilleray VJ, Clemens MJ, Hensold JO. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation. Oncogene 2002; 21: 5325-5334
-
(2002)
Oncogene
, vol.21
, pp. 5325-5334
-
-
Horton, L.E.1
Bushell, M.2
Barth-Baus, D.3
Tilleray, V.J.4
Clemens, M.J.5
Hensold, J.O.6
-
45
-
-
23344447873
-
Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
-
Kulikov R, Boehme KA, Blattner C. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Mol Cell Biol 2005; 25: 7170-7180
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7170-7180
-
-
Kulikov, R.1
Boehme, K.A.2
Blattner, C.3
-
46
-
-
78649712949
-
MTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
-
Oh WJ, Wu CC, Kim SJ, Facchinetti V, Julien LA, Finlan M, et al. mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J 2010; 29: 3939-3951
-
(2010)
EMBO J
, vol.29
, pp. 3939-3951
-
-
Oh, W.J.1
Wu, C.C.2
Kim, S.J.3
Facchinetti, V.4
Julien, L.A.5
Finlan, M.6
-
47
-
-
79959568260
-
Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1
-
Keshwani MM, von Daake S, Newton AC, Harris TK, Taylor SS. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1). J Biol Chem 2011; 286: 23552-23558
-
(2011)
J Biol Chem
, vol.286
, pp. 23552-23558
-
-
Keshwani, M.M.1
Von Daake, S.2
Newton, A.C.3
Harris, T.K.4
Taylor, S.S.5
-
48
-
-
84856772150
-
GSK-3b inhibition in pancreatic cancer
-
Lowy AM, Leach SD, Philip PA (eds Springer: US
-
Kim GP, Billadeau DD. GSK-3b inhibition in pancreatic cancer. In: Lowy AM, Leach SD, Philip PA (eds). Pancreatic Cancer. Springer: US, 2008, pp 635-646
-
(2008)
Pancreatic Cancer
, pp. 635-646
-
-
Kim, G.P.1
Billadeau, D.D.2
-
49
-
-
16844374033
-
Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells
-
Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD. Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 2005; 65: 2076-2081
-
(2005)
Cancer Res
, vol.65
, pp. 2076-2081
-
-
Ougolkov, A.V.1
Fernandez-Zapico, M.E.2
Savoy, D.N.3
Urrutia, R.A.4
Billadeau, D.D.5
-
50
-
-
77953312514
-
Glycogen synthase kinase 3 beta: Can it be a target for oral cancer
-
Mishra R. Glycogen synthase kinase 3 beta: Can it be a target for oral cancer. Mol Cancer 2010; 9: 144
-
(2010)
Mol Cancer
, vol.9
, pp. 144
-
-
Mishra, R.1
-
51
-
-
23044444841
-
Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
-
Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, et al. Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 2005; 334: 1365-1373
-
(2005)
Biochem Biophys Res Commun
, vol.334
, pp. 1365-1373
-
-
Shakoori, A.1
Ougolkov, A.2
Yu, Z.W.3
Zhang, B.4
Modarressi, M.H.5
Billadeau, D.D.6
-
52
-
-
77950353276
-
ERK2 but not ERK1 induces epithelial-To-mesenchymal transformation via DEF motif-dependent signaling events
-
Shin S, Dimitri CA, Yoon SO, Dowdle W, Blenis J. ERK2 but not ERK1 induces epithelial-To-mesenchymal transformation via DEF motif-dependent signaling events. Mol Cell 2010; 38: 114-127
-
(2010)
Mol Cell
, vol.38
, pp. 114-127
-
-
Shin, S.1
Dimitri, C.A.2
Yoon, S.O.3
Dowdle, W.4
Blenis, J.5
-
53
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
-
54
-
-
34347242470
-
Ras/erk signaling promotes site-specific ribosomal protein s6 phosphorylation via rsk and stimulates cap-dependent translation
-
Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, et al. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 2007; 282: 14056-14064
-
(2007)
J Biol Chem
, vol.282
, pp. 14056-14064
-
-
Roux, P.P.1
Shahbazian, D.2
Vu, H.3
Holz, M.K.4
Cohen, M.S.5
Taunton, J.6
-
55
-
-
77950886468
-
Methods for detecting autophagy and determining autophagy-induced cell death
-
Chen Y, Azad MB, Gibson SB. Methods for detecting autophagy and determining autophagy-induced cell death. Can J Physiol Pharmacol 2010; 88: 285-295
-
(2010)
Can J Physiol Pharmacol
, vol.88
, pp. 285-295
-
-
Chen, Y.1
Azad, M.B.2
Gibson, S.B.3
-
56
-
-
34547782316
-
Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents
-
Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, et al. Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents. Cancer Sci 2007; 98: 1388-1393
-
(2007)
Cancer Sci
, vol.98
, pp. 1388-1393
-
-
Shakoori, A.1
Mai, W.2
Miyashita, K.3
Yasumoto, K.4
Takahashi, Y.5
Ooi, A.6
-
57
-
-
72549086625
-
Deregulated GSK3(beta) sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase
-
Mai W, Kawakami K, Shakoori A, Kyo S, Miyashita K, Yokoi K, et al. Deregulated GSK3(beta) sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase. Clin Cancer Res 2009; 15: 6810-6819
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6810-6819
-
-
Mai, W.1
Kawakami, K.2
Shakoori, A.3
Kyo, S.4
Miyashita, K.5
Yokoi, K.6
-
58
-
-
59249088869
-
Monitoring mammalian target of rapamycin (mTOR) activity
-
Ikenoue T, Hong S, Inoki K. Monitoring mammalian target of rapamycin (mTOR) activity. Methods Enzymol 2009; 452: 165-180
-
(2009)
Methods Enzymol
, vol.452
, pp. 165-180
-
-
Ikenoue, T.1
Hong, S.2
Inoki, K.3
-
59
-
-
34248650697
-
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
-
Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, Spellman PT, et al. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol 2007; 1: 84-96
-
(2007)
Mol Oncol
, vol.1
, pp. 84-96
-
-
Kenny, P.A.1
Lee, G.Y.2
Myers, C.A.3
Neve, R.M.4
Semeiks, J.R.5
Spellman, P.T.6
-
60
-
-
34247864012
-
Three-dimensional culture models of normal and malignant breast epithelial cells
-
Lee GY, Kenny PA, Lee EH, Bissell MJ. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 2007; 4: 359-365.
-
(2007)
Nat Methods
, vol.4
, pp. 359-365
-
-
Lee, G.Y.1
Kenny, P.A.2
Lee, E.H.3
Bissell, M.J.4
|