메뉴 건너뛰기




Volumn 33, Issue 13, 2014, Pages 1690-1699

Glycogen synthase kinase-3β positively regulates protein synthesis and cell proliferation through the regulation of translation initiation factor 4E-binding protein 1

Author keywords

4E BP1; GSK 3; Translation

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; INITIATION FACTOR 4E BINDING PROTEIN 1; RAPAMYCIN; UNCLASSIFIED DRUG;

EID: 84898014860     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2013.113     Document Type: Article
Times cited : (88)

References (60)
  • 1
    • 34547691071 scopus 로고    scopus 로고
    • The role of GSK3 in glucose homeostasis and the development of insulin resistance
    • Lee J, Kim MS. The role of GSK3 in glucose homeostasis and the development of insulin resistance. Diabetes Res Clin Pract 2007; 77(Suppl 1): S49-S57
    • (2007) Diabetes Res Clin Pract , vol.77 , Issue.SUPPL. . 1
    • Lee, J.1    Kim, M.S.2
  • 2
    • 77954874401 scopus 로고    scopus 로고
    • GSK3 signalling in neural development
    • Hur EM, Zhou FQ. GSK3 signalling in neural development. Nat Rev Neurosci 2010; 11: 539-551
    • (2010) Nat Rev Neurosci , vol.11 , pp. 539-551
    • Hur, E.M.1    Zhou, F.Q.2
  • 3
    • 57349143530 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy
    • Luo J. Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy. Cancer Lett 2009; 273: 194-200
    • (2009) Cancer Lett , vol.273 , pp. 194-200
    • Luo, J.1
  • 4
    • 54549120290 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 and cancer: Good cop, bad cop
    • Patel S, Woodgett J. Glycogen synthase kinase-3 and cancer: Good cop, bad cop? Cancer Cell 2008; 14: 351-353
    • (2008) Cancer Cell , vol.14 , pp. 351-353
    • Patel, S.1    Woodgett, J.2
  • 5
    • 0036190970 scopus 로고    scopus 로고
    • Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways
    • Manoukian AS, Woodgett JR. Role of glycogen synthase kinase-3 in cancer: Regulation by Wnts and other signaling pathways. Adv Cancer Res 2002; 84: 203-229
    • (2002) Adv Cancer Res , vol.84 , pp. 203-229
    • Manoukian, A.S.1    Woodgett, J.R.2
  • 7
    • 77953233857 scopus 로고    scopus 로고
    • GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis
    • Wang Z, Iwasaki M, Ficara F, Lin C, Matheny C, Wong SH, et al. GSK-3 promotes conditional association of CREB and its coactivators with MEIS1 to facilitate HOX-mediated transcription and oncogenesis. Cancer Cell 2010; 17: 597-608
    • (2010) Cancer Cell , vol.17 , pp. 597-608
    • Wang, Z.1    Iwasaki, M.2    Ficara, F.3    Lin, C.4    Matheny, C.5    Wong, S.H.6
  • 8
    • 55249120170 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
    • Wang Z, Smith KS, Murphy M, Piloto O, Somervaille TC, Cleary ML. Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy. Nature 2008; 455: 1205-1209
    • (2008) Nature , vol.455 , pp. 1205-1209
    • Wang, Z.1    Smith, K.S.2    Murphy, M.3    Piloto, O.4    Somervaille, T.C.5    Cleary, M.L.6
  • 9
    • 82755187773 scopus 로고    scopus 로고
    • Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation
    • Shin S, Wolgamott L, Yu Y, Blenis J, Yoon SO. Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation. Proc Natl Acad Sci USA 2011; 108: E1204-E1213
    • (2011) Proc Natl Acad Sci USA , vol.108
    • Shin, S.1    Wolgamott, L.2    Yu, Y.3    Blenis, J.4    Yoon, S.O.5
  • 10
    • 34547114509 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells
    • Ougolkov AV, Bone ND, Fernandez-Zapico ME, Kay NE, Billadeau DD. Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells. Blood 2007; 110: 735-742
    • (2007) Blood , vol.110 , pp. 735-742
    • Ougolkov, A.V.1    Bone, N.D.2    Fernandez-Zapico, M.E.3    Kay, N.E.4    Billadeau, D.D.5
  • 11
    • 0034612636 scopus 로고    scopus 로고
    • Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation
    • Hoeflich KP, Luo J, Rubie EA, Tsao MS, Jin O, Woodgett JR. Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation. Nature 2000; 406: 86-90
    • (2000) Nature , vol.406 , pp. 86-90
    • Hoeflich, K.P.1    Luo, J.2    Rubie, E.A.3    Tsao, M.S.4    Jin, O.5    Woodgett, J.R.6
  • 12
    • 0037172661 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta modulates notch signaling and stability
    • Foltz DR, Santiago MC, Berechid BE, Nye JS. Glycogen synthase kinase-3beta modulates notch signaling and stability. Curr Biol 2002; 12: 1006-1011
    • (2002) Curr Biol , vol.12 , pp. 1006-1011
    • Foltz, D.R.1    Santiago, M.C.2    Berechid, B.E.3    Nye, J.S.4
  • 13
    • 10744232627 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta
    • Qu L, Huang S, Baltzis D, Rivas-Estilla AM, Pluquet O, Hatzoglou M, et al. Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta. Genes Dev 2004; 18: 261-277
    • (2004) Genes Dev , vol.18 , pp. 261-277
    • Qu, L.1    Huang, S.2    Baltzis, D.3    Rivas-Estilla, A.M.4    Pluquet, O.5    Hatzoglou, M.6
  • 15
    • 80755132133 scopus 로고    scopus 로고
    • Kinome siRNAphosphoproteomic screen identifies networks regulating AKT signaling
    • Lu Y, Muller M, Smith D, Dutta B, Komurov K, Iadevaia S, et al. Kinome siRNAphosphoproteomic screen identifies networks regulating AKT signaling. Oncogene 2011; 30: 4567-4577
    • (2011) Oncogene , vol.30 , pp. 4567-4577
    • Lu, Y.1    Muller, M.2    Smith, D.3    Dutta, B.4    Komurov, K.5    Iadevaia, S.6
  • 16
    • 33646795341 scopus 로고    scopus 로고
    • Targeting gsk-3 a promising approach for cancer therapy
    • Ougolkov AV, Billadeau DD. Targeting GSK-3: A promising approach for cancer therapy? Future Oncol 2006; 2: 91-100
    • (2006) Future Oncol , vol.2 , pp. 91-100
    • Ougolkov, A.V.1    Billadeau, D.D.2
  • 17
  • 18
    • 77949659245 scopus 로고    scopus 로고
    • Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: An in vivo bioluminescence imaging study
    • Zeng Q, Yang Z, Gao YJ, Yuan H, Cui K, Shi Y, et al. Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: An in vivo bioluminescence imaging study. Eur J Cancer 2010; 46: 1132-1143
    • (2010) Eur J Cancer , vol.46 , pp. 1132-1143
    • Zeng, Q.1    Yang, Z.2    Gao, Y.J.3    Yuan, H.4    Cui, K.5    Shi, Y.6
  • 19
    • 79955637310 scopus 로고    scopus 로고
    • The biological and therapeutic relevance of mRNA translation in cancer
    • Blagden SP, Willis AE. The biological and therapeutic relevance of mRNA translation in cancer. Nat Rev Clin Oncol 2011; 8: 280-291
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 280-291
    • Blagden, S.P.1    Willis, A.E.2
  • 20
    • 57149118433 scopus 로고    scopus 로고
    • A protein that replaces the entire cellular eIF4F complex
    • Mir MA, Panganiban AT. A protein that replaces the entire cellular eIF4F complex. EMBO J 2008; 27: 3129-3139
    • (2008) EMBO J , vol.27 , pp. 3129-3139
    • Mir, M.A.1    Panganiban, A.T.2
  • 22
    • 78049381472 scopus 로고    scopus 로고
    • New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress
    • Ayuso MI, Hernandez-Jimenez M, Martin ME, Salinas M, Alcazar A. New hierarchical phosphorylation pathway of the translational repressor eIF4E-binding protein 1 (4E-BP1) in ischemia-reperfusion stress. J Biol Chem 2010; 285: 34355-34363
    • (2010) J Biol Chem , vol.285 , pp. 34355-34363
    • Ayuso, M.I.1    Hernandez-Jimenez, M.2    Martin, M.E.3    Salinas, M.4    Alcazar, A.5
  • 23
    • 38449110890 scopus 로고    scopus 로고
    • Methods for studying signal-dependent regulation of translation factor activity
    • Wang X, Proud CG. Methods for studying signal-dependent regulation of translation factor activity. Methods Enzymol 2007; 431: 113-142
    • (2007) Methods Enzymol , vol.431 , pp. 113-142
    • Wang, X.1    Proud, C.G.2
  • 25
    • 0037373346 scopus 로고    scopus 로고
    • The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation
    • Wang X, Li W, Parra JL, Beugnet A, Proud CG. The C terminus of initiation factor 4E-binding protein 1 contains multiple regulatory features that influence its function and phosphorylation. Mol Cell Biol 2003; 23: 1546-1557
    • (2003) Mol Cell Biol , vol.23 , pp. 1546-1557
    • Wang, X.1    Li, W.2    Parra, J.L.3    Beugnet, A.4    Proud, C.G.5
  • 26
    • 80052899298 scopus 로고    scopus 로고
    • A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells
    • Tullai JW, Graham JR, Cooper GM. A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells. Cell Cycle 2011; 10: 3072-3077
    • (2011) Cell Cycle , vol.10 , pp. 3072-3077
    • Tullai, J.W.1    Graham, J.R.2    Cooper, G.M.3
  • 27
    • 0037205315 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development
    • Hardt SE, Sadoshima J. Glycogen synthase kinase-3beta: A novel regulator of cardiac hypertrophy and development. Circ Res 2002; 90: 1055-1063
    • (2002) Circ Res , vol.90 , pp. 1055-1063
    • Hardt, S.E.1    Sadoshima, J.2
  • 28
    • 0036090823 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3: An emerging therapeutic target
    • Eldar-Finkelman H. Glycogen synthase kinase 3: An emerging therapeutic target. Trends Mol Med 2002; 8: 126-132
    • (2002) Trends Mol Med , vol.8 , pp. 126-132
    • Eldar-Finkelman, H.1
  • 29
    • 0037383322 scopus 로고    scopus 로고
    • GSK-3: Tricks of the trade for a multi-Tasking kinase
    • Doble BW, Woodgett JR. GSK-3: Tricks of the trade for a multi-Tasking kinase. J Cell Sci 2003; 116: 1175-1186
    • (2003) J Cell Sci , vol.116 , pp. 1175-1186
    • Doble, B.W.1    Woodgett, J.R.2
  • 30
    • 79958696336 scopus 로고    scopus 로고
    • Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling
    • Yu Y, Yoon SO, Poulogiannis G, Yang Q, Ma XM, Villen J, et al. Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. Science 2011; 332: 1322-1326
    • (2011) Science , vol.332 , pp. 1322-1326
    • Yu, Y.1    Yoon, S.O.2    Poulogiannis, G.3    Yang, Q.4    Ma, X.M.5    Villen, J.6
  • 31
    • 80555129351 scopus 로고    scopus 로고
    • Oncogenic and tumor suppressor functions of notch in cancer: It's notch what you think
    • Lobry C, Oh P, Aifantis I. Oncogenic and tumor suppressor functions of Notch in cancer: It's NOTCH what you think. J Exp Med 2011; 208: 1931-1935
    • (2011) J Exp Med , vol.208 , pp. 1931-1935
    • Lobry, C.1    Oh, P.2    Aifantis, I.3
  • 33
    • 58049192725 scopus 로고    scopus 로고
    • Long-Term all-cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta-Analysis
    • Barone BB, Yeh HC, Snyder CF, Peairs KS, Stein KB, Derr RL, et al. Long-Term all-cause mortality in cancer patients with preexisting diabetes mellitus: A systematic review and meta-Analysis. JAMA 2008; 300: 2754-2764
    • (2008) JAMA , vol.300 , pp. 2754-2764
    • Barone, B.B.1    Yeh, H.C.2    Snyder, C.F.3    Peairs, K.S.4    Stein, K.B.5    Derr, R.L.6
  • 35
    • 77953262873 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 and leukemia: Restoring the balance
    • Birch NW, Zeleznik-Le NJ. Glycogen synthase kinase-3 and leukemia: Restoring the balance. Cancer Cell 2010; 17: 529-531
    • (2010) Cancer Cell , vol.17 , pp. 529-531
    • Birch, N.W.1    Zeleznik-Le, N.J.2
  • 36
    • 4544220704 scopus 로고    scopus 로고
    • Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity
    • Um SH, Frigerio F, Watanabe M, Picard F, Joaquin M, Sticker M, et al. Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity. Nature 2004; 431: 200-205
    • (2004) Nature , vol.431 , pp. 200-205
    • Um, S.H.1    Frigerio, F.2    Watanabe, M.3    Picard, F.4    Joaquin, M.5    Sticker, M.6
  • 37
    • 0035815669 scopus 로고    scopus 로고
    • Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver
    • Jiang YP, Ballou LM, Lin RZ. Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver. J Biol Chem 2001; 276: 10943-10951
    • (2001) J Biol Chem , vol.276 , pp. 10943-10951
    • Jiang, Y.P.1    Ballou, L.M.2    Lin, R.Z.3
  • 38
    • 56249147509 scopus 로고    scopus 로고
    • Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-Type-specific repression of mRNA translation
    • Choo AY, Yoon SO, Kim SG, Roux PP, Blenis J. Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-Type-specific repression of mRNA translation. Proc Natl Acad Sci USA 2008; 105: 17414-17419
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17414-17419
    • Choo, A.Y.1    Yoon, S.O.2    Kim, S.G.3    Roux, P.P.4    Blenis, J.5
  • 39
    • 84863116501 scopus 로고    scopus 로고
    • Mtor-independent 4e-bp1 phosphorylation is associated with cancer resistance to mtor kinase inhibitors
    • Zhang Y, Zheng XF. mTOR-independent 4E-BP1 phosphorylation is associated with cancer resistance to mTOR kinase inhibitors. Cell Cycle 2012; 11: 594-603
    • (2012) Cell Cycle , vol.11 , pp. 594-603
    • Zhang, Y.1    Zheng, X.F.2
  • 40
    • 77649286736 scopus 로고    scopus 로고
    • Genetic dissection of the oncogenic mtor pathway reveals druggable addiction to translational control via 4ebp-eif4e
    • Hsieh AC, Costa M, Zollo O, Davis C, Feldman ME, Testa JR, et al. Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. Cancer Cell 2010; 17: 249-261
    • (2010) Cancer Cell , vol.17 , pp. 249-261
    • Hsieh, A.C.1    Costa, M.2    Zollo, O.3    Davis, C.4    Feldman, M.E.5    Testa, J.R.6
  • 41
    • 80052592002 scopus 로고    scopus 로고
    • A directed protein interaction network for investigating intracellular signal transduction
    • Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, et al. A directed protein interaction network for investigating intracellular signal transduction. Sci Signal 2011; 4: Rs8
    • (2011) Sci Signal , vol.4
    • Vinayagam, A.1    Stelzl, U.2    Foulle, R.3    Plassmann, S.4    Zenkner, M.5    Timm, J.6
  • 43
    • 77951231349 scopus 로고    scopus 로고
    • MTOR and cancer: Many loops in one pathway
    • Efeyan A, Sabatini DM. mTOR and cancer: Many loops in one pathway. Curr Opin Cell Biol 2010; 22: 169-176
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 169-176
    • Efeyan, A.1    Sabatini, D.M.2
  • 44
    • 0037043851 scopus 로고    scopus 로고
    • P53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation
    • Horton LE, Bushell M, Barth-Baus D, Tilleray VJ, Clemens MJ, Hensold JO. p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation. Oncogene 2002; 21: 5325-5334
    • (2002) Oncogene , vol.21 , pp. 5325-5334
    • Horton, L.E.1    Bushell, M.2    Barth-Baus, D.3    Tilleray, V.J.4    Clemens, M.J.5    Hensold, J.O.6
  • 45
    • 23344447873 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance
    • Kulikov R, Boehme KA, Blattner C. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Mol Cell Biol 2005; 25: 7170-7180
    • (2005) Mol Cell Biol , vol.25 , pp. 7170-7180
    • Kulikov, R.1    Boehme, K.A.2    Blattner, C.3
  • 46
    • 78649712949 scopus 로고    scopus 로고
    • MTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide
    • Oh WJ, Wu CC, Kim SJ, Facchinetti V, Julien LA, Finlan M, et al. mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide. EMBO J 2010; 29: 3939-3951
    • (2010) EMBO J , vol.29 , pp. 3939-3951
    • Oh, W.J.1    Wu, C.C.2    Kim, S.J.3    Facchinetti, V.4    Julien, L.A.5    Finlan, M.6
  • 47
    • 79959568260 scopus 로고    scopus 로고
    • Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1
    • Keshwani MM, von Daake S, Newton AC, Harris TK, Taylor SS. Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1). J Biol Chem 2011; 286: 23552-23558
    • (2011) J Biol Chem , vol.286 , pp. 23552-23558
    • Keshwani, M.M.1    Von Daake, S.2    Newton, A.C.3    Harris, T.K.4    Taylor, S.S.5
  • 48
    • 84856772150 scopus 로고    scopus 로고
    • GSK-3b inhibition in pancreatic cancer
    • Lowy AM, Leach SD, Philip PA (eds Springer: US
    • Kim GP, Billadeau DD. GSK-3b inhibition in pancreatic cancer. In: Lowy AM, Leach SD, Philip PA (eds). Pancreatic Cancer. Springer: US, 2008, pp 635-646
    • (2008) Pancreatic Cancer , pp. 635-646
    • Kim, G.P.1    Billadeau, D.D.2
  • 49
    • 16844374033 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells
    • Ougolkov AV, Fernandez-Zapico ME, Savoy DN, Urrutia RA, Billadeau DD. Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells. Cancer Res 2005; 65: 2076-2081
    • (2005) Cancer Res , vol.65 , pp. 2076-2081
    • Ougolkov, A.V.1    Fernandez-Zapico, M.E.2    Savoy, D.N.3    Urrutia, R.A.4    Billadeau, D.D.5
  • 50
    • 77953312514 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 beta: Can it be a target for oral cancer
    • Mishra R. Glycogen synthase kinase 3 beta: Can it be a target for oral cancer. Mol Cancer 2010; 9: 144
    • (2010) Mol Cancer , vol.9 , pp. 144
    • Mishra, R.1
  • 51
    • 23044444841 scopus 로고    scopus 로고
    • Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation
    • Shakoori A, Ougolkov A, Yu ZW, Zhang B, Modarressi MH, Billadeau DD, et al. Deregulated GSK3beta activity in colorectal cancer: Its association with tumor cell survival and proliferation. Biochem Biophys Res Commun 2005; 334: 1365-1373
    • (2005) Biochem Biophys Res Commun , vol.334 , pp. 1365-1373
    • Shakoori, A.1    Ougolkov, A.2    Yu, Z.W.3    Zhang, B.4    Modarressi, M.H.5    Billadeau, D.D.6
  • 52
    • 77950353276 scopus 로고    scopus 로고
    • ERK2 but not ERK1 induces epithelial-To-mesenchymal transformation via DEF motif-dependent signaling events
    • Shin S, Dimitri CA, Yoon SO, Dowdle W, Blenis J. ERK2 but not ERK1 induces epithelial-To-mesenchymal transformation via DEF motif-dependent signaling events. Mol Cell 2010; 38: 114-127
    • (2010) Mol Cell , vol.38 , pp. 114-127
    • Shin, S.1    Dimitri, C.A.2    Yoon, S.O.3    Dowdle, W.4    Blenis, J.5
  • 53
    • 33845209913 scopus 로고    scopus 로고
    • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
    • Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, et al. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006; 10: 515-527
    • (2006) Cancer Cell , vol.10 , pp. 515-527
    • Neve, R.M.1    Chin, K.2    Fridlyand, J.3    Yeh, J.4    Baehner, F.L.5    Fevr, T.6
  • 54
    • 34347242470 scopus 로고    scopus 로고
    • Ras/erk signaling promotes site-specific ribosomal protein s6 phosphorylation via rsk and stimulates cap-dependent translation
    • Roux PP, Shahbazian D, Vu H, Holz MK, Cohen MS, Taunton J, et al. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation. J Biol Chem 2007; 282: 14056-14064
    • (2007) J Biol Chem , vol.282 , pp. 14056-14064
    • Roux, P.P.1    Shahbazian, D.2    Vu, H.3    Holz, M.K.4    Cohen, M.S.5    Taunton, J.6
  • 55
    • 77950886468 scopus 로고    scopus 로고
    • Methods for detecting autophagy and determining autophagy-induced cell death
    • Chen Y, Azad MB, Gibson SB. Methods for detecting autophagy and determining autophagy-induced cell death. Can J Physiol Pharmacol 2010; 88: 285-295
    • (2010) Can J Physiol Pharmacol , vol.88 , pp. 285-295
    • Chen, Y.1    Azad, M.B.2    Gibson, S.B.3
  • 56
    • 34547782316 scopus 로고    scopus 로고
    • Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents
    • Shakoori A, Mai W, Miyashita K, Yasumoto K, Takahashi Y, Ooi A, et al. Inhibition of GSK-3 beta activity attenuates proliferation of human colon cancer cells in rodents. Cancer Sci 2007; 98: 1388-1393
    • (2007) Cancer Sci , vol.98 , pp. 1388-1393
    • Shakoori, A.1    Mai, W.2    Miyashita, K.3    Yasumoto, K.4    Takahashi, Y.5    Ooi, A.6
  • 57
    • 72549086625 scopus 로고    scopus 로고
    • Deregulated GSK3(beta) sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase
    • Mai W, Kawakami K, Shakoori A, Kyo S, Miyashita K, Yokoi K, et al. Deregulated GSK3(beta) sustains gastrointestinal cancer cells survival by modulating human telomerase reverse transcriptase and telomerase. Clin Cancer Res 2009; 15: 6810-6819
    • (2009) Clin Cancer Res , vol.15 , pp. 6810-6819
    • Mai, W.1    Kawakami, K.2    Shakoori, A.3    Kyo, S.4    Miyashita, K.5    Yokoi, K.6
  • 58
    • 59249088869 scopus 로고    scopus 로고
    • Monitoring mammalian target of rapamycin (mTOR) activity
    • Ikenoue T, Hong S, Inoki K. Monitoring mammalian target of rapamycin (mTOR) activity. Methods Enzymol 2009; 452: 165-180
    • (2009) Methods Enzymol , vol.452 , pp. 165-180
    • Ikenoue, T.1    Hong, S.2    Inoki, K.3
  • 59
    • 34248650697 scopus 로고    scopus 로고
    • The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
    • Kenny PA, Lee GY, Myers CA, Neve RM, Semeiks JR, Spellman PT, et al. The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol 2007; 1: 84-96
    • (2007) Mol Oncol , vol.1 , pp. 84-96
    • Kenny, P.A.1    Lee, G.Y.2    Myers, C.A.3    Neve, R.M.4    Semeiks, J.R.5    Spellman, P.T.6
  • 60
    • 34247864012 scopus 로고    scopus 로고
    • Three-dimensional culture models of normal and malignant breast epithelial cells
    • Lee GY, Kenny PA, Lee EH, Bissell MJ. Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods 2007; 4: 359-365.
    • (2007) Nat Methods , vol.4 , pp. 359-365
    • Lee, G.Y.1    Kenny, P.A.2    Lee, E.H.3    Bissell, M.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.