Clonotype-specific avidity influences the dynamics and hierarchy of virus-specific regulatory and effector CD4+ T-cell responses

European Journal of Immunology

Volumn 44, Issue 4, 2014, Pages 1058-1068

  Liu, Jie ^a   Cao, Shirley ^a   Peppers, Gretchen ^a   Kim, Sung Han ^a   Graham, Barney S ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Precursor frequency; Respiratory syncytial virus; T cell hierarchy; T cell receptor (TCR) avidity; Treg cell

Indexed keywords

EPITOPE; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; DYNAMICS; IMMUNOPATHOLOGY; IN VITRO STUDY; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PATHOGEN CLEARANCE; PRIMARY INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SECONDARY INFECTION; T LYMPHOCYTE;

PRECURSOR FREQUENCY; RESPIRATORY SYNCYTIAL VIRUS; T-CELL HIERARCHY; T-CELL RECEPTOR (TCR) AVIDITY; TREG CELL;

ANIMALS; BINDING, COMPETITIVE; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; CLONE CELLS; EPITOPES, T-LYMPHOCYTE; FLOW CYTOMETRY; HOST-PATHOGEN INTERACTIONS; HUMANS; KINETICS; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUSES; T-LYMPHOCYTES, REGULATORY;

EID: 84898014205     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201343766     Document Type: Article

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