-
2
-
-
0017078404
-
Ageing and degeneration in the macular region: A clinico-pathological study
-
S.H. Sarks Ageing and degeneration in the macular region: a clinico-pathological study Brit. J. Ophthalmol. 60 1976 324 341
-
(1976)
Brit. J. Ophthalmol.
, vol.60
, pp. 324-341
-
-
Sarks, S.H.1
-
4
-
-
17244379811
-
Complement factor H polymorphism and age-related macular degeneration
-
A.O. Edwards, R. Ritter 3rd, K.J. Abel, A. Manning, and C. Panhuysen et al. Complement factor H polymorphism and age-related macular degeneration Science 308 2005 421 424
-
(2005)
Science
, vol.308
, pp. 421-424
-
-
Edwards, A.O.1
Ritter III, R.2
Abel, K.J.3
Manning, A.4
Panhuysen, C.5
-
5
-
-
21044453724
-
A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration
-
G.S. Hageman, D.H. Anderson, L.V. Johnson, L.S. Hancox, and A.J. Taiber et al. A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration Proc. Natl. Acad. Sci. U S A 102 2005 7227 7232
-
(2005)
Proc. Natl. Acad. Sci. U S A
, vol.102
, pp. 7227-7232
-
-
Hageman, G.S.1
Anderson, D.H.2
Johnson, L.V.3
Hancox, L.S.4
Taiber, A.J.5
-
6
-
-
20244388812
-
Complement factor H variant increases the risk of age-related macular degeneration
-
J.L. Haines, M.A. Hauser, S. Schmidt, W.K. Scott, and L.M. Olson et al. Complement factor H variant increases the risk of age-related macular degeneration Science 308 2005 419 421
-
(2005)
Science
, vol.308
, pp. 419-421
-
-
Haines, J.L.1
Hauser, M.A.2
Schmidt, S.3
Scott, W.K.4
Olson, L.M.5
-
7
-
-
20244380171
-
Complement factor H polymorphism in age-related macular degeneration
-
R.J. Klein, C. Zeiss, E.Y. Chew, J.Y. Tsai, and R.S. Sackler et al. Complement factor H polymorphism in age-related macular degeneration Science 308 2005 385 389
-
(2005)
Science
, vol.308
, pp. 385-389
-
-
Klein, R.J.1
Zeiss, C.2
Chew, E.Y.3
Tsai, J.Y.4
Sackler, R.S.5
-
8
-
-
0036864198
-
Factor H family proteins: On complement, microbes and human diseases
-
P.F. Zipfel, C. Skerka, J. Hellwage, S.T. Jokiranta, and S. Meri et al. Factor H family proteins: on complement, microbes and human diseases Biochem. Soc. Trans. 30 2002 971 978
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 971-978
-
-
Zipfel, P.F.1
Skerka, C.2
Hellwage, J.3
Jokiranta, S.T.4
Meri, S.5
-
9
-
-
33749123246
-
A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration
-
A.E. Hughes, N. Orr, H. Esfandiary, M. Diaz-Torres, and T. Goodship et al. A common CFH haplotype, with deletion of CFHR1 and CFHR3, is associated with lower risk of age-related macular degeneration Nat. Genet. 38 2006 1173 1177
-
(2006)
Nat. Genet.
, vol.38
, pp. 1173-1177
-
-
Hughes, A.E.1
Orr, N.2
Esfandiary, H.3
Diaz-Torres, M.4
Goodship, T.5
-
10
-
-
78149270873
-
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)
-
L.G. Fritsche, N. Lauer, A. Hartmann, S. Stippa, and C.N. Keilhauer et al. An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD) Hum. Mol. Genet. 19 2010 4694 4704
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4694-4704
-
-
Fritsche, L.G.1
Lauer, N.2
Hartmann, A.3
Stippa, S.4
Keilhauer, C.N.5
-
11
-
-
34249697078
-
The clearance of apoptotic cells by complement
-
R. Flierman, and M.R. Daha The clearance of apoptotic cells by complement Immunobiology 212 2007 363 370
-
(2007)
Immunobiology
, vol.212
, pp. 363-370
-
-
Flierman, R.1
Daha, M.R.2
-
13
-
-
77249147331
-
The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited
-
D.H. Anderson, M.J. Radeke, N.B. Gallo, E.A. Chapin, and P.T. Johnson et al. The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited Prog. Retin. Eye Res. 29 2010 95 112
-
(2010)
Prog. Retin. Eye Res.
, vol.29
, pp. 95-112
-
-
Anderson, D.H.1
Radeke, M.J.2
Gallo, N.B.3
Chapin, E.A.4
Johnson, P.T.5
-
14
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
E.L. Gautier, T. Shay, J. Miller, M. Greter, and C. Jakubzick et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages Nat. Immunol. 13 2012 1118 1128
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
Shay, T.2
Miller, J.3
Greter, M.4
Jakubzick, C.5
-
15
-
-
79959966904
-
Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid
-
C. Luo, M. Chen, and H. Xu Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid Mol. Vis. 17 2011 1588 1597
-
(2011)
Mol. Vis.
, vol.17
, pp. 1588-1597
-
-
Luo, C.1
Chen, M.2
Xu, H.3
-
16
-
-
84875796877
-
Ubiquinone-quantum dot bioconjugates for in vitro and intracellular complex i sensing
-
W. Ma, L.X. Qin, F.T. Liu, Z. Gu, and J. Wang et al. Ubiquinone-quantum dot bioconjugates for in vitro and intracellular complex I sensing Sci. Rep. 3 2013 1537
-
(2013)
Sci. Rep.
, vol.3
, pp. 1537
-
-
Ma, W.1
Qin, L.X.2
Liu, F.T.3
Gu, Z.4
Wang, J.5
-
17
-
-
0034868775
-
Expression and regulation of complement factors H and i in rat and human cells: Some critical notes
-
G. Schlaf, T. Demberg, N. Beisel, H.L. Schieferdecker, and O. Gotze Expression and regulation of complement factors H and I in rat and human cells: some critical notes Mol. Immunol. 38 2001 231 239
-
(2001)
Mol. Immunol.
, vol.38
, pp. 231-239
-
-
Schlaf, G.1
Demberg, T.2
Beisel, N.3
Schieferdecker, H.L.4
Gotze, O.5
-
18
-
-
64249098087
-
Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis
-
M.R. Griffiths, J.W. Neal, M. Fontaine, T. Das, and P. Gasque Complement factor H, a marker of self protects against experimental autoimmune encephalomyelitis J. Immunol. 182 2009 4368 4377
-
(2009)
J. Immunol.
, vol.182
, pp. 4368-4377
-
-
Griffiths, M.R.1
Neal, J.W.2
Fontaine, M.3
Das, T.4
Gasque, P.5
-
19
-
-
0021736976
-
Localization of the complement-component-C3b-binding site and the cofactor activity for factor i in the 38 kDa tryptic fragment of factor H
-
J. Alsenz, J.D. Lambris, T.F. Schulz, and M.P. Dierich Localization of the complement-component-C3b-binding site and the cofactor activity for factor I in the 38 kDa tryptic fragment of factor H Biochem. J. 224 1984 389 398
-
(1984)
Biochem. J.
, vol.224
, pp. 389-398
-
-
Alsenz, J.1
Lambris, J.D.2
Schulz, T.F.3
Dierich, M.P.4
-
20
-
-
0029850245
-
Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H
-
S. Kuhn, and P.F. Zipfel Mapping of the domains required for decay acceleration activity of the human factor H-like protein 1 and factor H Eur. J. Immunol. 26 1996 2383 2387
-
(1996)
Eur. J. Immunol.
, vol.26
, pp. 2383-2387
-
-
Kuhn, S.1
Zipfel, P.F.2
-
21
-
-
0027496024
-
Characterization of factor H binding to human polymorphonuclear leukocytes
-
V.M. Avery, and D.L. Gordon Characterization of factor H binding to human polymorphonuclear leukocytes J. Immunol. 151 1993 5545 5553
-
(1993)
J. Immunol.
, vol.151
, pp. 5545-5553
-
-
Avery, V.M.1
Gordon, D.L.2
-
22
-
-
76249101650
-
Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3 mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity
-
J. Losse, P.F. Zipfel, and M. Jozsi Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3 mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity J. Immunol. 184 2010 912 921
-
(2010)
J. Immunol.
, vol.184
, pp. 912-921
-
-
Losse, J.1
Zipfel, P.F.2
Jozsi, M.3
-
23
-
-
0030590494
-
Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: Evidence for multiple interactions between H and surface bound C3b
-
T.S. Jokiranta, P.F. Zipfel, J. Hakulinen, S. Kuhn, and M.K. Pangburn et al. Analysis of the recognition mechanism of the alternative pathway of complement by monoclonal anti-factor H antibodies: evidence for multiple interactions between H and surface bound C3b FEBS Lett. 393 1996 297 302
-
(1996)
FEBS Lett.
, vol.393
, pp. 297-302
-
-
Jokiranta, T.S.1
Zipfel, P.F.2
Hakulinen, J.3
Kuhn, S.4
Pangburn, M.K.5
-
24
-
-
0038068044
-
A common site within factor H SCR 7 responsible for binding heparin C-reactive protein and streptococcal M protein
-
E. Giannakis, T.S. Jokiranta, D.A. Male, S. Ranganathan, and R.J. Ormsby et al. A common site within factor H SCR 7 responsible for binding heparin C-reactive protein and streptococcal M protein Eur. J. Immunol. 33 2003 962 969
-
(2003)
Eur. J. Immunol.
, vol.33
, pp. 962-969
-
-
Giannakis, E.1
Jokiranta, T.S.2
Male, D.A.3
Ranganathan, S.4
Ormsby, R.J.5
-
25
-
-
70449724676
-
Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H
-
M. Mihlan, S. Stippa, M. Jozsi, and P.F. Zipfel Monomeric CRP contributes to complement control in fluid phase and on cellular surfaces and increases phagocytosis by recruiting factor H Cell Death Differ. 16 2009 1630 1640
-
(2009)
Cell Death Differ.
, vol.16
, pp. 1630-1640
-
-
Mihlan, M.1
Stippa, S.2
Jozsi, M.3
Zipfel, P.F.4
-
26
-
-
80053904386
-
Complement factor H binds malondialdehyde epitopes and protects from oxidative stress
-
D. Weismann, K. Hartvigsen, N. Lauer, K.L. Bennett, and H.P. Scholl et al. Complement factor H binds malondialdehyde epitopes and protects from oxidative stress Nature 478 2011 76 81
-
(2011)
Nature
, vol.478
, pp. 76-81
-
-
Weismann, D.1
Hartvigsen, K.2
Lauer, N.3
Bennett, K.L.4
Scholl, H.P.5
-
27
-
-
0029763437
-
Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis
-
A.K. Sharma, and M.K. Pangburn Identification of three physically and functionally distinct binding sites for C3b in human complement factor H by deletion mutagenesis Proc. Natl. Acad. Sci. U S A 93 1996 10996 11001
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 10996-11001
-
-
Sharma, A.K.1
Pangburn, M.K.2
-
28
-
-
0032055196
-
Identification of the second heparin-binding domain in human complement factor H
-
T.K. Blackmore, J. Hellwage, T.A. Sadlon, N. Higgs, and P.F. Zipfel et al. Identification of the second heparin-binding domain in human complement factor H J. Immunol. 160 1998 3342 3348
-
(1998)
J. Immunol.
, vol.160
, pp. 3342-3348
-
-
Blackmore, T.K.1
Hellwage, J.2
Sadlon, T.A.3
Higgs, N.4
Zipfel, P.F.5
-
29
-
-
33747700932
-
His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form
-
S.J. Clark, V.A. Higman, B. Mulloy, S.J. Perkins, and S.M. Lea et al. His-384 allotypic variant of factor H associated with age-related macular degeneration has different heparin binding properties from the non-disease-associated form J. Biol. Chem. 281 2006 24713 24720
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 24713-24720
-
-
Clark, S.J.1
Higman, V.A.2
Mulloy, B.3
Perkins, S.J.4
Lea, S.M.5
-
30
-
-
0028875543
-
Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1
-
S. Kuhn, C. Skerka, and P.F. Zipfel Mapping of the complement regulatory domains in the human factor H-like protein 1 and in factor H1 J. Immunol. 155 1995 5663 5670
-
(1995)
J. Immunol.
, vol.155
, pp. 5663-5670
-
-
Kuhn, S.1
Skerka, C.2
Zipfel, P.F.3
-
31
-
-
84875239064
-
Dimerization of complement factor H-related proteins modulates complement activation in vivo
-
E. Goicoechea de Jorge, J.J. Caesar, T.H. Malik, M. Patel, and M. Colledge et al. Dimerization of complement factor H-related proteins modulates complement activation in vivo Proc. Natl. Acad. Sci. U S A 110 2013 4685 4690
-
(2013)
Proc. Natl. Acad. Sci. U S A
, vol.110
, pp. 4685-4690
-
-
Goicoechea De Jorge, E.1
Caesar, J.J.2
Malik, T.H.3
Patel, M.4
Colledge, M.5
-
32
-
-
0036699540
-
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H
-
M.C. Pickering, H.T. Cook, J. Warren, A.E. Bygrave, and J. Moss et al. Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor H Nat. Genet. 31 2002 424 428
-
(2002)
Nat. Genet.
, vol.31
, pp. 424-428
-
-
Pickering, M.C.1
Cook, H.T.2
Warren, J.3
Bygrave, A.E.4
Moss, J.5
-
33
-
-
0026019531
-
Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions
-
C. Timmann, M. Leippe, and R.D. Horstmann Two major serum components antigenically related to complement factor H are different glycosylation forms of a single protein with no factor H-like complement regulatory functions J. Immunol. 146 1991 1265 1270
-
(1991)
J. Immunol.
, vol.146
, pp. 1265-1270
-
-
Timmann, C.1
Leippe, M.2
Horstmann, R.D.3
-
34
-
-
70349441306
-
Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation
-
S. Heinen, A. Hartmann, N. Lauer, U. Wiehl, and H.M. Dahse et al. Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formation Blood 114 2009 2439 2447
-
(2009)
Blood
, vol.114
, pp. 2439-2447
-
-
Heinen, S.1
Hartmann, A.2
Lauer, N.3
Wiehl, U.4
Dahse, H.M.5
-
35
-
-
0032438352
-
Genetic risk of age-related maculopathy population-based familial aggregation study
-
C.C. Klaver, R.C. Wolfs, J.J. Assink, C.M. van Duijn, and A. Hofman et al. Genetic risk of age-related maculopathy population-based familial aggregation study Arch. Ophthalmol. 116 1998 1646 1651
-
(1998)
Arch. Ophthalmol.
, vol.116
, pp. 1646-1651
-
-
Klaver, C.C.1
Wolfs, R.C.2
Assink, J.J.3
Van Duijn, C.M.4
Hofman, A.5
-
36
-
-
0033833611
-
The second eye of Japanese patients with unilateral exudative age related macular degeneration
-
M. Uyama, K. Takahashi, N. Ida, M. Miyashiro, and A. Ando et al. The second eye of Japanese patients with unilateral exudative age related macular degeneration Brit. J. Ophthalmol. 84 2000 1018 1023
-
(2000)
Brit. J. Ophthalmol.
, vol.84
, pp. 1018-1023
-
-
Uyama, M.1
Takahashi, K.2
Ida, N.3
Miyashiro, M.4
Ando, A.5
-
37
-
-
33745728418
-
No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese
-
N. Gotoh, R. Yamada, H. Hiratani, V. Renault, and S. Kuroiwa et al. No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese Hum. Genet. 120 2006 139 143
-
(2006)
Hum. Genet.
, vol.120
, pp. 139-143
-
-
Gotoh, N.1
Yamada, R.2
Hiratani, H.3
Renault, V.4
Kuroiwa, S.5
-
38
-
-
77951622654
-
Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population
-
K. Mori, K. Horie-Inoue, P.L. Gehlbach, H. Takita, and S. Kabasawa et al. Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population Ophthalmology 117 2010 928 938
-
(2010)
Ophthalmology
, vol.117
, pp. 928-938
-
-
Mori, K.1
Horie-Inoue, K.2
Gehlbach, P.L.3
Takita, H.4
Kabasawa, S.5
-
39
-
-
32044474231
-
CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD
-
K.P. Magnusson, S. Duan, H. Sigurdsson, H. Petursson, and Z. Yang et al. CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD PLoS Med. 3 2006 e5
-
(2006)
PLoS Med.
, vol.3
, pp. 5
-
-
Magnusson, K.P.1
Duan, S.2
Sigurdsson, H.3
Petursson, H.4
Yang, Z.5
-
40
-
-
33746041795
-
Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration
-
D.D. Despriet, C.C. Klaver, J.C. Witteman, A.A. Bergen, and I. Kardys et al. Complement factor H polymorphism, complement activators, and risk of age-related macular degeneration JAMA 296 2006 301 309
-
(2006)
JAMA
, vol.296
, pp. 301-309
-
-
Despriet, D.D.1
Klaver, C.C.2
Witteman, J.C.3
Bergen, A.A.4
Kardys, I.5
-
41
-
-
34548418473
-
Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes
-
C.L. Thompson, B.E. Klein, R. Klein, Z. Xu, and J. Capriotti et al. Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes Hum. Mol. Genet. 16 2007 2135 2148
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 2135-2148
-
-
Thompson, C.L.1
Klein, B.E.2
Klein, R.3
Xu, Z.4
Capriotti, J.5
-
42
-
-
84860585042
-
Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models
-
Y. Yu, R. Reynolds, B. Rosner, M.J. Daly, and J.M. Seddon Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models Invest. Ophthalmol. Vis. Sci. 53 2012 1548 1556
-
(2012)
Invest. Ophthalmol. Vis. Sci.
, vol.53
, pp. 1548-1556
-
-
Yu, Y.1
Reynolds, R.2
Rosner, B.3
Daly, M.J.4
Seddon, J.M.5
-
43
-
-
84875706378
-
Seven new loci associated with age-related macular degeneration
-
439e431-432
-
L.G. Fritsche, W. Chen, M. Schu, B.L. Yaspan, and Y. Yu et al. Seven new loci associated with age-related macular degeneration Nat. Genet. 45 2013 433 439 439e431-432
-
(2013)
Nat. Genet.
, vol.45
, pp. 433-439
-
-
Fritsche, L.G.1
Chen, W.2
Schu, M.3
Yaspan, B.L.4
Yu, Y.5
-
44
-
-
34247470278
-
Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration
-
J.M. Seddon, P.J. Francis, S. George, D.W. Schultz, and B. Rosner et al. Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration JAMA 297 2007 1793 1800
-
(2007)
JAMA
, vol.297
, pp. 1793-1800
-
-
Seddon, J.M.1
Francis, P.J.2
George, S.3
Schultz, D.W.4
Rosner, B.5
-
45
-
-
84865282678
-
Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids
-
P.X. Shaw, L. Zhang, M. Zhang, H. Du, and L. Zhao et al. Complement factor H genotypes impact risk of age-related macular degeneration by interaction with oxidized phospholipids Proc. Natl. Acad. Sci. U S A 109 2012 13757 13762
-
(2012)
Proc. Natl. Acad. Sci. U S A
, vol.109
, pp. 13757-13762
-
-
Shaw, P.X.1
Zhang, L.2
Zhang, M.3
Du, H.4
Zhao, L.5
-
46
-
-
33748325757
-
CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration
-
M. Li, P. Atmaca-Sonmez, M. Othman, K.E. Branham, and R. Khanna et al. CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration Nat. Genet. 38 2006 1049 1054
-
(2006)
Nat. Genet.
, vol.38
, pp. 1049-1054
-
-
Li, M.1
Atmaca-Sonmez, P.2
Othman, M.3
Branham, K.E.4
Khanna, R.5
-
47
-
-
82255162545
-
A rare penetrant mutation in CFH confers high risk of age-related macular degeneration
-
S. Raychaudhuri, O. Iartchouk, K. Chin, P.L. Tan, and A.K. Tai et al. A rare penetrant mutation in CFH confers high risk of age-related macular degeneration Nat. Genet. 43 2011 1232 1236
-
(2011)
Nat. Genet.
, vol.43
, pp. 1232-1236
-
-
Raychaudhuri, S.1
Iartchouk, O.2
Chin, K.3
Tan, P.L.4
Tai, A.K.5
-
48
-
-
33645451557
-
Factor H and atypical hemolytic uremic syndrome: Mutations in the C-terminus cause structural changes and defective recognition functions
-
M. Jozsi, S. Heinen, A. Hartmann, C.W. Ostrowicz, and S. Halbich et al. Factor H and atypical hemolytic uremic syndrome: mutations in the C-terminus cause structural changes and defective recognition functions J. Am. Soc. Nephrol. 17 2006 170 177
-
(2006)
J. Am. Soc. Nephrol.
, vol.17
, pp. 170-177
-
-
Jozsi, M.1
Heinen, S.2
Hartmann, A.3
Ostrowicz, C.W.4
Halbich, S.5
-
49
-
-
69449090499
-
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity
-
A. Tortajada, T. Montes, R. Martinez-Barricarte, B.P. Morgan, and C.L. Harris et al. The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity Hum. Mol. Genet. 18 2009 3452 3461
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3452-3461
-
-
Tortajada, A.1
Montes, T.2
Martinez-Barricarte, R.3
Morgan, B.P.4
Harris, C.L.5
-
50
-
-
33847153137
-
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: Characterization, ethnic distribution and evolutionary implications
-
G.S. Hageman, L.S. Hancox, A.J. Taiber, K.M. Gehrs, and D.H. Anderson et al. Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications Ann. Med. 38 2006 592 604
-
(2006)
Ann. Med.
, vol.38
, pp. 592-604
-
-
Hageman, G.S.1
Hancox, L.S.2
Taiber, A.J.3
Gehrs, K.M.4
Anderson, D.H.5
-
51
-
-
41149171882
-
Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration
-
K.L. Spencer, M.A. Hauser, L.M. Olson, S. Schmidt, and W.K. Scott et al. Deletion of CFHR3 and CFHR1 genes in age-related macular degeneration Hum. Mol. Genet. 17 2008 971 977
-
(2008)
Hum. Mol. Genet.
, vol.17
, pp. 971-977
-
-
Spencer, K.L.1
Hauser, M.A.2
Olson, L.M.3
Schmidt, S.4
Scott, W.K.5
-
52
-
-
57649215855
-
Variation near complement factor i is associated with risk of advanced AMD
-
J.A. Fagerness, J.B. Maller, B.M. Neale, R.C. Reynolds, and M.J. Daly et al. Variation near complement factor I is associated with risk of advanced AMD Eur. J. Hum. Genet. 17 2009 100 104
-
(2009)
Eur. J. Hum. Genet.
, vol.17
, pp. 100-104
-
-
Fagerness, J.A.1
Maller, J.B.2
Neale, B.M.3
Reynolds, R.C.4
Daly, M.J.5
-
53
-
-
33645419787
-
Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration
-
B. Gold, J.E. Merriam, J. Zernant, L.S. Hancox, and A.J. Taiber et al. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration Nat. Genet. 38 2006 458 462
-
(2006)
Nat. Genet.
, vol.38
, pp. 458-462
-
-
Gold, B.1
Merriam, J.E.2
Zernant, J.3
Hancox, L.S.4
Taiber, A.J.5
-
54
-
-
34748819371
-
Variation in complement factor 3 is associated with risk of age-related macular degeneration
-
J.B. Maller, J.A. Fagerness, R.C. Reynolds, B.M. Neale, and M.J. Daly et al. Variation in complement factor 3 is associated with risk of age-related macular degeneration Nat. Genet. 39 2007 1200 1201
-
(2007)
Nat. Genet.
, vol.39
, pp. 1200-1201
-
-
Maller, J.B.1
Fagerness, J.A.2
Reynolds, R.C.3
Neale, B.M.4
Daly, M.J.5
-
55
-
-
34247147197
-
Estimation of systemic complement C3 activity in age-related macular degeneration
-
S. Sivaprasad, T. Adewoyin, T.A. Bailey, S.S. Dandekar, and S. Jenkins et al. Estimation of systemic complement C3 activity in age-related macular degeneration Arch. Ophthalmol. 125 2007 515 519
-
(2007)
Arch. Ophthalmol.
, vol.125
, pp. 515-519
-
-
Sivaprasad, S.1
Adewoyin, T.2
Bailey, T.A.3
Dandekar, S.S.4
Jenkins, S.5
-
56
-
-
73349112242
-
Plasma complement components and activation fragments: Associations with age-related macular degeneration genotypes and phenotypes
-
R. Reynolds, M.E. Hartnett, J.P. Atkinson, P.C. Giclas, and B. Rosner et al. Plasma complement components and activation fragments: associations with age-related macular degeneration genotypes and phenotypes Invest. Ophthalmol. Vis. Sci. 50 2009 5818 5827
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 5818-5827
-
-
Reynolds, R.1
Hartnett, M.E.2
Atkinson, J.P.3
Giclas, P.C.4
Rosner, B.5
-
57
-
-
49749150467
-
Systemic complement activation in age-related macular degeneration
-
H.P. Scholl, P. Charbel Issa, M. Walier, S. Janzer, and B. Pollok-Kopp et al. Systemic complement activation in age-related macular degeneration PLoS One 3 2008 e2593
-
(2008)
PLoS One
, vol.3
, pp. 2593
-
-
Scholl, H.P.1
Charbel Issa, P.2
Walier, M.3
Janzer, S.4
Pollok-Kopp, B.5
-
58
-
-
79957691055
-
Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk
-
M. Heurich, R. Martinez-Barricarte, N.J. Francis, D.L. Roberts, and S. Rodriguez de Cordoba et al. Common polymorphisms in C3, factor B, and factor H collaborate to determine systemic complement activity and disease risk Proc. Natl. Acad. Sci. U S A 108 2011 8761 8766
-
(2011)
Proc. Natl. Acad. Sci. U S A
, vol.108
, pp. 8761-8766
-
-
Heurich, M.1
Martinez-Barricarte, R.2
Francis, N.J.3
Roberts, D.L.4
Rodriguez De Cordoba, S.5
-
59
-
-
84871876710
-
Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration
-
K.M. Loyet, L.E. Deforge, K.J. Katschke Jr., L. Diehl, and R.R. Graham et al. Activation of the alternative complement pathway in vitreous is controlled by genetics in age-related macular degeneration Invest. Ophthalmol. Vis. Sci. 53 2012 6628 6637
-
(2012)
Invest. Ophthalmol. Vis. Sci.
, vol.53
, pp. 6628-6637
-
-
Loyet, K.M.1
Deforge, L.E.2
Katschke, Jr.K.J.3
Diehl, L.4
Graham, R.R.5
-
60
-
-
0034012166
-
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
-
R.F. Mullins, S.R. Russell, D.H. Anderson, and G.S. Hageman Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease FASEB J. 14 2000 835 846
-
(2000)
FASEB J.
, vol.14
, pp. 835-846
-
-
Mullins, R.F.1
Russell, S.R.2
Anderson, D.H.3
Hageman, G.S.4
-
61
-
-
84881161121
-
Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation
-
S. Khandhadia, S. Hakobyan, L.Z. Heng, J. Gibson, and D.H. Adams et al. Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation Ophthalmology 2013
-
(2013)
Ophthalmology
-
-
Khandhadia, S.1
Hakobyan, S.2
Heng, L.Z.3
Gibson, J.4
Adams, D.H.5
-
62
-
-
2442580225
-
Genetic and environmental factors influencing the human factor H plasma levels
-
J. Esparza-Gordillo, J.M. Soria, A. Buil, L. Almasy, and J. Blangero et al. Genetic and environmental factors influencing the human factor H plasma levels Immunogenetics 56 2004 77 82
-
(2004)
Immunogenetics
, vol.56
, pp. 77-82
-
-
Esparza-Gordillo, J.1
Soria, J.M.2
Buil, A.3
Almasy, L.4
Blangero, J.5
-
63
-
-
44649151935
-
Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: Application to assessing risk of age-related macular degeneration
-
S. Hakobyan, C.L. Harris, A. Tortajada, E. Goicochea de Jorge, and A. Garcia-Layana et al. Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration Invest. Ophthalmol. Vis. Sci. 49 2008 1983 1990
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 1983-1990
-
-
Hakobyan, S.1
Harris, C.L.2
Tortajada, A.3
Goicochea De Jorge, E.4
Garcia-Layana, A.5
-
64
-
-
33751243644
-
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid
-
P.T. Johnson, K.E. Betts, M.J. Radeke, G.S. Hageman, and D.H. Anderson et al. Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroid Proc. Natl. Acad. Sci. U S A 103 2006 17456 17461
-
(2006)
Proc. Natl. Acad. Sci. U S A
, vol.103
, pp. 17456-17461
-
-
Johnson, P.T.1
Betts, K.E.2
Radeke, M.J.3
Hageman, G.S.4
Anderson, D.H.5
-
65
-
-
0037396993
-
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome
-
T. Manuelian, J. Hellwage, S. Meri, J. Caprioli, and M. Noris et al. Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome J. Clin. Invest. 111 2003 1181 1190
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1181-1190
-
-
Manuelian, T.1
Hellwage, J.2
Meri, S.3
Caprioli, J.4
Noris, M.5
-
66
-
-
84874253499
-
Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions
-
S.J. Clark, L.A. Ridge, A.P. Herbert, S. Hakobyan, and B. Mulloy et al. Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions J. Immunol. 190 2013 2049 2057
-
(2013)
J. Immunol.
, vol.190
, pp. 2049-2057
-
-
Clark, S.J.1
Ridge, L.A.2
Herbert, A.P.3
Hakobyan, S.4
Mulloy, B.5
-
67
-
-
0029741681
-
Identification of glycosaminoglycans in age-related macular deposits
-
M. Kliffen, C.M. Mooy, T.M. Luider, J.G. Huijmans, and S. Kerkvliet et al. Identification of glycosaminoglycans in age-related macular deposits Arch. Ophthalmol. 114 1996 1009 1014
-
(1996)
Arch. Ophthalmol.
, vol.114
, pp. 1009-1014
-
-
Kliffen, M.1
Mooy, C.M.2
Luider, T.M.3
Huijmans, J.G.4
Kerkvliet, S.5
-
68
-
-
36749004311
-
Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction
-
P.J. Coffey, C. Gias, C.J. McDermott, P. Lundh, and M.C. Pickering et al. Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction Proc. Natl. Acad. Sci. U S A 104 2007 16651 16656
-
(2007)
Proc. Natl. Acad. Sci. U S A
, vol.104
, pp. 16651-16656
-
-
Coffey, P.J.1
Gias, C.2
McDermott, C.J.3
Lundh, P.4
Pickering, M.C.5
-
69
-
-
77957329394
-
Role of ocular complement factor H in a murine model of choroidal neovascularization
-
V.V. Lyzogubov, R.G. Tytarenko, P. Jha, J. Liu, and N.S. Bora et al. Role of ocular complement factor H in a murine model of choroidal neovascularization Am. J. Pathol. 177 2010 1870 1880
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 1870-1880
-
-
Lyzogubov, V.V.1
Tytarenko, R.G.2
Jha, P.3
Liu, J.4
Bora, N.S.5
-
70
-
-
79955050748
-
Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings
-
R.L. Ufret-Vincenty, B. Aredo, X. Liu, A. McMahon, and P.W. Chen et al. Transgenic mice expressing variants of complement factor H develop AMD-like retinal findings Invest. Ophthalmol. Vis. Sci. 51 2012 5878 5887
-
(2012)
Invest. Ophthalmol. Vis. Sci.
, vol.51
, pp. 5878-5887
-
-
Ufret-Vincenty, R.L.1
Aredo, B.2
Liu, X.3
McMahon, A.4
Chen, P.W.5
|