Uncontrolled c3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor h

Nature Genetics

Volumn 31, Issue 4, 2002, Pages 424-428

  Pickering, Matthew C ^a   Cook, H Terence ^a   Warren, Joanna ^a   Bygrave, Anne E ^a   Moss, Jill ^b   Walport, Mark J ^a   Botto, Marina ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; COMPLEMENT ACTIVATION; COMPLEMENT DEFICIENCY; DISSOCIATION; GENE MUTATION; HYDROLYSIS; KIDNEY INJURY; MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; COMPLEMENT ACTIVATION; COMPLEMENT C3; COMPLEMENT C9; COMPLEMENT FACTOR H; DISEASE MODELS, ANIMAL; FEMALE; GLOMERULONEPHRITIS; KIDNEY; MALE; MICE; MICE, INBRED STRAINS; MICE, MUTANT STRAINS; MUTATION;

ACARI; ANIMALIA;

EID: 0036699540     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng912     Document Type: Article

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