-
1
-
-
78650553199
-
pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation
-
doi: 10.1073/pnas.1014403107
-
An, M., Wijesinghe, D., Andreev, O. A., Reshetnyak, Y. K., and Engelman, D. M. (2010). pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation. Proc. Natl. Acad. Sci. U.S.A. 107, 20246-20250. doi: 10.1073/pnas.1014403107.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 20246-20250
-
-
An, M.1
Wijesinghe, D.2
Andreev, O.A.3
Reshetnyak, Y.K.4
Engelman, D.M.5
-
2
-
-
34249949775
-
Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo
-
doi: 10.1073/pnas.0702439104
-
Andreev, O. A., Dupuy, A. D., Segala, M., Sandugu, S., Serra, D. A., Chichester, C. O., et al. (2007). Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo. Proc. Natl. Acad. Sci. U.S.A. 104, 7893-7898. doi: 10.1073/pnas.0702439104.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 7893-7898
-
-
Andreev, O.A.1
Dupuy, A.D.2
Segala, M.3
Sandugu, S.4
Serra, D.A.5
Chichester, C.O.6
-
3
-
-
77749313553
-
Targeting acidic diseased tissue: new technology based on use of the pH (Low) Insertion Peptide (pHLIP)
-
Andreev, O. A., Engelman, D. M., and Reshetnyak, Y. K. (2009). Targeting acidic diseased tissue: new technology based on use of the pH (Low) Insertion Peptide (pHLIP). Chim. Oggi 27, 34-37.
-
(2009)
Chim. Oggi
, vol.27
, pp. 34-37
-
-
Andreev, O.A.1
Engelman, D.M.2
Reshetnyak, Y.K.3
-
4
-
-
78049333901
-
pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents
-
doi: 10.3109/09687688.2010.509285
-
Andreev, O. A., Engelman, D. M., and Reshetnyak, Y. K. (2010a). pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents. Mol. Membr. Biol. 27, 341-352. doi: 10.3109/09687688.2010.509285.
-
(2010)
Mol. Membr. Biol.
, vol.27
, pp. 341-352
-
-
Andreev, O.A.1
Engelman, D.M.2
Reshetnyak, Y.K.3
-
5
-
-
77749233798
-
pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path
-
doi: 10.1073/pnas.0914330107
-
Andreev, O. A., Karabadzhak, A. G., Weerakkody, D., Andreev, G. O., Engelman, D. M., and Reshetnyak, Y. K. (2010b). pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path. Proc. Natl. Acad. Sci. U.S.A. 107, 4081-4086. doi: 10.1073/pnas.0914330107.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 4081-4086
-
-
Andreev, O.A.1
Karabadzhak, A.G.2
Weerakkody, D.3
Andreev, G.O.4
Engelman, D.M.5
Reshetnyak, Y.K.6
-
6
-
-
80054741747
-
Roles of carboxyl groups in the transmembrane insertion of peptides
-
doi: 10.1016/j.jmb.2011.08.010
-
Barrera, F. N., Weerakkody, D., Anderson, M., Andreev, O. A., Reshetnyak, Y. K., and Engelman, D. M. (2011). Roles of carboxyl groups in the transmembrane insertion of peptides. J. Mol. Biol. 413, 359-371. doi: 10.1016/j.jmb.2011.08.010.
-
(2011)
J. Mol. Biol.
, vol.413
, pp. 359-371
-
-
Barrera, F.N.1
Weerakkody, D.2
Anderson, M.3
Andreev, O.A.4
Reshetnyak, Y.K.5
Engelman, D.M.6
-
7
-
-
84878782419
-
Cell-penetrating peptides: 20 years later, where do we stand?
-
doi: 10.1016/j.febslet.2013.04.031
-
Bechara, C., and Sagan, S. (2013). Cell-penetrating peptides: 20 years later, where do we stand? FEBS Lett. 587, 1693-1702. doi: 10.1016/j.febslet.2013.04.031.
-
(2013)
FEBS Lett.
, vol.587
, pp. 1693-1702
-
-
Bechara, C.1
Sagan, S.2
-
8
-
-
19444382074
-
The engineering of membrane-permeable peptides
-
doi: 10.1016/j.ab.2005.03.026
-
Carrigan, C. N., and Imperiali, B. (2005). The engineering of membrane-permeable peptides. Anal. Biochem. 341, 290-298. doi: 10.1016/j.ab.2005.03.026.
-
(2005)
Anal. Biochem.
, vol.341
, pp. 290-298
-
-
Carrigan, C.N.1
Imperiali, B.2
-
9
-
-
33748988741
-
Tryptophan-and arginine-rich antimicrobial peptides: structures and mechanisms of action
-
doi: 10.1016/j.bbamem.2006.04.006
-
Chan, D. I., Prenner, E. J., and Vogel, H. J. (2006). Tryptophan-and arginine-rich antimicrobial peptides: structures and mechanisms of action. Biochim. Biophys. Acta 1758, 1184-1202. doi: 10.1016/j.bbamem.2006.04.006.
-
(2006)
Biochim. Biophys. Acta
, vol.1758
, pp. 1184-1202
-
-
Chan, D.I.1
Prenner, E.J.2
Vogel, H.J.3
-
10
-
-
84869103855
-
Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities
-
doi: 10.1126/science.1226338
-
Cheng, Z., Al Zaki, A., Hui, J. Z., Muzykantov, V. R., and Tsourkas, A. (2012). Multifunctional nanoparticles: cost versus benefit of adding targeting and imaging capabilities. Science 338, 903-910. doi: 10.1126/science.1226338.
-
(2012)
Science
, vol.338
, pp. 903-910
-
-
Cheng, Z.1
Al Zaki, A.2
Hui, J.Z.3
Muzykantov, V.R.4
Tsourkas, A.5
-
11
-
-
77953935500
-
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
-
doi: 10.1111/j.1582-4934.2009.00994.x
-
Chiche, J., Brahimi-Horn, M. C., and Pouyssegur, J. (2010). Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer. J. Cell. Mol. Med. 14, 771-794. doi: 10.1111/j.1582-4934.2009.00994.x.
-
(2010)
J. Cell. Mol. Med.
, vol.14
, pp. 771-794
-
-
Chiche, J.1
Brahimi-Horn, M.C.2
Pouyssegur, J.3
-
12
-
-
84865125806
-
Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation
-
doi: 10.1021/bc3000222
-
Daumar, P., Wanger-Baumann, C. A., Pillarsetty, N., Fabrizio, L., Carlin, S. D., Andreev, O. A., et al. (2012). Efficient (18)F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjug. Chem. 23, 1557-1566. doi: 10.1021/bc3000222.
-
(2012)
Bioconjug. Chem.
, vol.23
, pp. 1557-1566
-
-
Daumar, P.1
Wanger-Baumann, C.A.2
Pillarsetty, N.3
Fabrizio, L.4
Carlin, S.D.5
Andreev, O.A.6
-
13
-
-
84857134071
-
pH-controlled delivery of luminescent europium coated nanoparticles into platelets
-
doi: 10.1073/pnas.1112132109
-
Davies, A., Lewis, D. J., Watson, S. P., Thomas, S. G., and Pikramenou, Z. (2012). pH-controlled delivery of luminescent europium coated nanoparticles into platelets. Proc. Natl. Acad. Sci. U.S.A. 109, 1862-1867. doi: 10.1073/pnas.1112132109.
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 1862-1867
-
-
Davies, A.1
Lewis, D.J.2
Watson, S.P.3
Thomas, S.G.4
Pikramenou, Z.5
-
14
-
-
51049090204
-
Nanoparticle therapeutics: an emerging treatment modality for cancer
-
doi: 10.1038/nrd2614
-
Davis, M. E., Chen, Z. G., and Shin, D. M. (2008). Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 7, 771-782. doi: 10.1038/nrd2614.
-
(2008)
Nat. Rev. Drug Discov.
, vol.7
, pp. 771-782
-
-
Davis, M.E.1
Chen, Z.G.2
Shin, D.M.3
-
15
-
-
14644439267
-
Cancer nanotechnology: opportunities and challenges
-
doi: 10.1038/nrc1566
-
Ferrari, M. (2005). Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 5, 161-171. doi: 10.1038/nrc1566.
-
(2005)
Nat. Rev. Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
16
-
-
34447094919
-
Glycolysis in cancer: a potential target for therapy
-
doi: 10.1016/j.biocel.2007.03.021
-
Gatenby, R. A., and Gillies, R. J. (2007). Glycolysis in cancer: a potential target for therapy. Int. J. Biochem. Cell Biol. 39, 1358-1366. doi: 10.1016/j.biocel.2007.03.021.
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 1358-1366
-
-
Gatenby, R.A.1
Gillies, R.J.2
-
17
-
-
0029971428
-
Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer
-
Gerweck, L. E., and Seetharaman, K. (1996). Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer. Cancer Res. 56, 1194-1198.
-
(1996)
Cancer Res.
, vol.56
, pp. 1194-1198
-
-
Gerweck, L.E.1
Seetharaman, K.2
-
18
-
-
84862757952
-
Evolutionary dynamics of carcinogenesis and why targeted therapy does not work
-
doi: 10.1038/nrc3298
-
Gillies, R. J., Verduzco, D., and Gatenby, R. A. (2012). Evolutionary dynamics of carcinogenesis and why targeted therapy does not work. Nat. Rev. Cancer 12, 487-493. doi: 10.1038/nrc3298.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 487-493
-
-
Gillies, R.J.1
Verduzco, D.2
Gatenby, R.A.3
-
19
-
-
68149163521
-
Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy
-
doi: 10.1517/17425240902932908
-
Gindy, M. E., and Prud'homme, R. K. (2009). Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy. Expert Opin. Drug Deliv. 6, 865-878. doi: 10.1517/17425240902932908.
-
(2009)
Expert Opin. Drug Deliv.
, vol.6
, pp. 865-878
-
-
Gindy, M.E.1
Prud'homme, R.K.2
-
20
-
-
77953599629
-
Heterogeneous diffusion of a membrane-bound pHLIP peptide
-
doi: 10.1016/j.bpj.2010.03.050
-
Guo, L., and Gai, F. (2010). Heterogeneous diffusion of a membrane-bound pHLIP peptide. Biophys. J. 98, 2914-2922. doi: 10.1016/j.bpj.2010.03.050.
-
(2010)
Biophys. J.
, vol.98
, pp. 2914-2922
-
-
Guo, L.1
Gai, F.2
-
21
-
-
84887210246
-
pH-controlled delivery of nanoparticles into tumor cells
-
doi: 10.1002/adhm.201300013
-
Han, L., Ma, H., Guo, Y., Kuang, Y., He, X., and Jiang, C. (2013). pH-controlled delivery of nanoparticles into tumor cells. Adv. Healthc. Mater. 2, 1435-1439. doi: 10.1002/adhm.201300013.
-
(2013)
Adv. Healthc. Mater.
, vol.2
, pp. 1435-1439
-
-
Han, L.1
Ma, H.2
Guo, Y.3
Kuang, Y.4
He, X.5
Jiang, C.6
-
22
-
-
0036001159
-
Structural basis of perturbed pKa values of catalytic groups in enzyme active sites
-
doi: 10.1080/15216540211468
-
Harris, T. K., and Turner, G. J. (2002). Structural basis of perturbed pKa values of catalytic groups in enzyme active sites. IUBMB Life 53, 85-98. doi: 10.1080/15216540211468.
-
(2002)
IUBMB Life
, vol.53
, pp. 85-98
-
-
Harris, T.K.1
Turner, G.J.2
-
23
-
-
79960825218
-
Imaging pH and metastasis
-
doi: 10.1002/nbm.1644
-
Hashim, A. I., Zhang, X., Wojtkowiak, J. W., Martinez, G. V., and Gillies, R. J. (2011). Imaging pH and metastasis. NMR Biomed. 24, 582-591. doi: 10.1002/nbm.1644.
-
(2011)
NMR Biomed.
, vol.24
, pp. 582-591
-
-
Hashim, A.I.1
Zhang, X.2
Wojtkowiak, J.W.3
Martinez, G.V.4
Gillies, R.J.5
-
24
-
-
0030708557
-
A biophysical study of integral membrane protein folding
-
doi: 10.1021/bi970146j
-
Hunt, J. F., Earnest, T. N., Bousche, O., Kalghatgi, K., Reilly, K., Horvath, C., et al. (1997). A biophysical study of integral membrane protein folding. Biochemistry 36, 15156-15176. doi: 10.1021/bi970146j.
-
(1997)
Biochemistry
, vol.36
, pp. 15156-15176
-
-
Hunt, J.F.1
Earnest, T.N.2
Bousche, O.3
Kalghatgi, K.4
Reilly, K.5
Horvath, C.6
-
25
-
-
84859901776
-
Modulation of the pHLIP transmembrane helix insertion pathway
-
doi: 10.1016/j.bpj.2012.03.021
-
Karabadzhak, A. G., Weerakkody, D., Wijesinghe, D., Thakur, M. S., Engelman, D. M., Andreev, O. A., et al. (2012). Modulation of the pHLIP transmembrane helix insertion pathway. Biophys. J. 102, 1846-1855. doi: 10.1016/j.bpj.2012.03.021.
-
(2012)
Biophys. J.
, vol.102
, pp. 1846-1855
-
-
Karabadzhak, A.G.1
Weerakkody, D.2
Wijesinghe, D.3
Thakur, M.S.4
Engelman, D.M.5
Andreev, O.A.6
-
26
-
-
84873333450
-
Peptide targeting and imaging of damaged lung tissue in influenza-infected mice
-
doi: 10.2217/fmb.12.134
-
Li, N., Yin, L., Thevenin, D., Yamada, Y., Limmon, G., Chen, J., et al. (2013). Peptide targeting and imaging of damaged lung tissue in influenza-infected mice. Future Microbiol. 8, 257-269. doi: 10.2217/fmb.12.134.
-
(2013)
Future Microbiol.
, vol.8
, pp. 257-269
-
-
Li, N.1
Yin, L.2
Thevenin, D.3
Yamada, Y.4
Limmon, G.5
Chen, J.6
-
27
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
doi: 10.1016/S0169-409X(00)00129-0
-
Lipinski, C. A., Lombardo, F., Dominy, B. W., and Feeney, P. J. (2001). Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. 46, 3-26. doi: 10.1016/S0169-409X(00)00129-0.
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
28
-
-
84873088126
-
Optical molecular imaging detects changes in extracellular pH with the development of head and neck cancer
-
doi: 10.1002/ijc.27837
-
Loja, M. N., Luo, Z., Greg Farwell, D., Luu, Q. C., Donald, P. J., Amott, D., et al. (2013). Optical molecular imaging detects changes in extracellular pH with the development of head and neck cancer. Int. J. Cancer 132, 1613-1623. doi: 10.1002/ijc.27837.
-
(2013)
Int. J. Cancer
, vol.132
, pp. 1613-1623
-
-
Loja, M.N.1
Luo, Z.2
Greg Farwell, D.3
Luu, Q.C.4
Donald, P.J.5
Amott, D.6
-
29
-
-
84870434595
-
In vivo pH imaging with (99m)Tc-pHLIP
-
doi: 10.1007/s11307-012-0549-z
-
Macholl, S., Morrison, M. S., Iveson, P., Arbo, B. E., Andreev, O. A., Reshetnyak, Y. K., et al. (2012). In vivo pH imaging with (99m)Tc-pHLIP. Mol. Imaging Biol. 14, 725-734. doi: 10.1007/s11307-012-0549-z.
-
(2012)
Mol. Imaging Biol.
, vol.14
, pp. 725-734
-
-
Macholl, S.1
Morrison, M.S.2
Iveson, P.3
Arbo, B.E.4
Andreev, O.A.5
Reshetnyak, Y.K.6
-
30
-
-
77954352201
-
alpha-Amanitin induced apoptosis in primary cultured dog hepatocytes
-
doi: 10.2478/v10042-010-0010-6
-
Magdalan, J., Ostrowska, A., Piotrowska, A., Izykowska, I., Nowak, M., Gomulkiewicz, A., et al. (2010). alpha-Amanitin induced apoptosis in primary cultured dog hepatocytes. Folia Histochem. Cytobiol. 48, 58-62. doi: 10.2478/v10042-010-0010-6.
-
(2010)
Folia Histochem. Cytobiol.
, vol.48
, pp. 58-62
-
-
Magdalan, J.1
Ostrowska, A.2
Piotrowska, A.3
Izykowska, I.4
Nowak, M.5
Gomulkiewicz, A.6
-
31
-
-
84860142832
-
Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma
-
doi: 10.1093/jnci/djs140
-
Moldenhauer, G., Salnikov, A. V., Luttgau, S., Herr, I., Anderl, J., and Faulstich, H. (2012). Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma. J. Natl. Cancer Inst. 104, 622-634. doi: 10.1093/jnci/djs140.
-
(2012)
J. Natl. Cancer Inst.
, vol.104
, pp. 622-634
-
-
Moldenhauer, G.1
Salnikov, A.V.2
Luttgau, S.3
Herr, I.4
Anderl, J.5
Faulstich, H.6
-
32
-
-
84874056993
-
Antiproliferative effect of pHLIP-amanitin
-
doi: 10.1021/bi301647y
-
Moshnikova, A., Moshnikova, V., Andreev, O. A., and Reshetnyak, Y. K. (2013). Antiproliferative effect of pHLIP-amanitin. Biochemistry 52, 1171-1178. doi: 10.1021/bi301647y.
-
(2013)
Biochemistry
, vol.52
, pp. 1171-1178
-
-
Moshnikova, A.1
Moshnikova, V.2
Andreev, O.A.3
Reshetnyak, Y.K.4
-
33
-
-
77952530942
-
Tuning the insertion properties of pHLIP
-
doi: 10.1016/j.bbamem.2009.08.023
-
Musial-Siwek, M., Karabadzhak, A., Andreev, O. A., Reshetnyak, Y. K., and Engelman, D. M. (2010). Tuning the insertion properties of pHLIP. Biochim. Biophys. Acta 1798, 1041-1046. doi: 10.1016/j.bbamem.2009.08.023.
-
(2010)
Biochim. Biophys. Acta
, vol.1798
, pp. 1041-1046
-
-
Musial-Siwek, M.1
Karabadzhak, A.2
Andreev, O.A.3
Reshetnyak, Y.K.4
Engelman, D.M.5
-
34
-
-
27844485836
-
Protein translocation by the Sec61/SecY channel
-
doi: 10.1146/annurev.cellbio.21.012704.133214
-
Osborne, A. R., Rapoport, T. A., and Van Den Berg, B. (2005). Protein translocation by the Sec61/SecY channel. Annu. Rev. Cell Dev. Biol. 21, 529-550. doi: 10.1146/annurev.cellbio.21.012704.133214.
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 529-550
-
-
Osborne, A.R.1
Rapoport, T.A.2
Van Den Berg, B.3
-
35
-
-
0032927078
-
Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy
-
doi: 10.1016/S0006-2952(98)00306-2
-
Raghunand, N., Altbach, M. I., Van Sluis, R., Baggett, B., Taylor, C. W., Bhujwalla, Z. M., et al. (1999). Plasmalemmal pH-gradients in drug-sensitive and drug-resistant MCF-7 human breast carcinoma xenografts measured by 31P magnetic resonance spectroscopy. Biochem. Pharmacol. 57, 309-312. doi: 10.1016/S0006-2952(98)00306-2.
-
(1999)
Biochem. Pharmacol.
, vol.57
, pp. 309-312
-
-
Raghunand, N.1
Altbach, M.I.2
Van Sluis, R.3
Baggett, B.4
Taylor, C.W.5
Bhujwalla, Z.M.6
-
36
-
-
33646272211
-
Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix
-
doi: 10.1073/pnas.0601463103
-
Reshetnyak, Y. K., Andreev, O. A., Lehnert, U., and Engelman, D. M. (2006). Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix. Proc. Natl. Acad. Sci. U.S.A. 103, 6460-6465. doi: 10.1073/pnas.0601463103.
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 6460-6465
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Lehnert, U.3
Engelman, D.M.4
-
37
-
-
55749112330
-
Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane
-
doi: 10.1073/pnas.0804746105
-
Reshetnyak, Y. K., Andreev, O. A., Segala, M., Markin, V. S., and Engelman, D. M. (2008). Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane. Proc. Natl. Acad. Sci. U.S.A. 105, 15340-15345. doi: 10.1073/pnas.0804746105.
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 15340-15345
-
-
Reshetnyak, Y.K.1
Andreev, O.A.2
Segala, M.3
Markin, V.S.4
Engelman, D.M.5
-
38
-
-
34848885103
-
A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers
-
doi: 10.1529/biophysj.107.109967
-
Reshetnyak, Y. K., Segala, M., Andreev, O. A., and Engelman, D. M. (2007). A monomeric membrane peptide that lives in three worlds: in solution, attached to, and inserted across lipid bilayers. Biophys. J. 93, 2363-2372. doi: 10.1529/biophysj.107.109967.
-
(2007)
Biophys. J.
, vol.93
, pp. 2363-2372
-
-
Reshetnyak, Y.K.1
Segala, M.2
Andreev, O.A.3
Engelman, D.M.4
-
39
-
-
84855683946
-
Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP
-
doi: 10.1007/s11307-010-0457-z
-
Reshetnyak, Y. K., Yao, L., Zheng, S., Kuznetsov, S., Engelman, D. M., and Andreev, O. A. (2011). Measuring tumor aggressiveness and targeting metastatic lesions with fluorescent pHLIP. Mol. Imaging Biol. 13, 1146-1156. doi: 10.1007/s11307-010-0457-z.
-
(2011)
Mol. Imaging Biol.
, vol.13
, pp. 1146-1156
-
-
Reshetnyak, Y.K.1
Yao, L.2
Zheng, S.3
Kuznetsov, S.4
Engelman, D.M.5
Andreev, O.A.6
-
40
-
-
85044534648
-
Acute liver failure caused by amanita phalloides poisoning
-
doi: 10.1155/2012/487480
-
Santi, L., Maggioli, C., Mastroroberto, M., Tufoni, M., Napoli, L., and Caraceni, P. (2012). Acute liver failure caused by amanita phalloides poisoning. Int. J. Hepatol. 2012, 487480. doi: 10.1155/2012/487480.
-
(2012)
Int. J. Hepatol.
, vol.2012
, pp. 487480
-
-
Santi, L.1
Maggioli, C.2
Mastroroberto, M.3
Tufoni, M.4
Napoli, L.5
Caraceni, P.6
-
41
-
-
69549108017
-
Accurate analysis of tumor margins using a fluorescent ph low insertion peptide (pHLIP)
-
doi: 10.3390/ijms10083478
-
Segala, J., Engelman, D. M., Reshetnyak, Y. K., and Andreev, O. A. (2009). Accurate analysis of tumor margins using a fluorescent ph low insertion peptide (pHLIP). Int. J. Mol. Sci. 10, 3478-3487. doi: 10.3390/ijms10083478.
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 3478-3487
-
-
Segala, J.1
Engelman, D.M.2
Reshetnyak, Y.K.3
Andreev, O.A.4
-
42
-
-
84871966458
-
pH (low) insertion peptide (pHLIP) targets ischemic myocardium
-
doi: 10.1073/pnas.1220038110
-
Sosunov, E. A., Anyukhovsky, E. P., Sosunov, A. A., Moshnikova, A., Wijesinghe, D., Engelman, D. M., et al. (2013). pH (low) insertion peptide (pHLIP) targets ischemic myocardium. Proc. Natl. Acad. Sci. U.S.A. 110, 82-86. doi: 10.1073/pnas.1220038110.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 82-86
-
-
Sosunov, E.A.1
Anyukhovsky, E.P.2
Sosunov, A.A.3
Moshnikova, A.4
Wijesinghe, D.5
Engelman, D.M.6
-
43
-
-
67749115965
-
Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas)
-
doi: 10.1016/j.jconrel.2009.05.019
-
Takayama, K., Nakase, I., Michiue, H., Takeuchi, T., Tomizawa, K., Matsui, H., et al. (2009). Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas). J. Control. Release 138, 128-133. doi: 10.1016/j.jconrel.2009.05.019.
-
(2009)
J. Control. Release
, vol.138
, pp. 128-133
-
-
Takayama, K.1
Nakase, I.2
Michiue, H.3
Takeuchi, T.4
Tomizawa, K.5
Matsui, H.6
-
44
-
-
67651095995
-
pHLIP-mediated translocation of membrane-impermeable molecules into cells
-
doi: 10.1016/j.chembiol.2009.06.006
-
Thevenin, D., An, M., and Engelman, D. M. (2009). pHLIP-mediated translocation of membrane-impermeable molecules into cells. Chem. Biol. 16, 754-762. doi: 10.1016/j.chembiol.2009.06.006.
-
(2009)
Chem. Biol.
, vol.16
, pp. 754-762
-
-
Thevenin, D.1
An, M.2
Engelman, D.M.3
-
45
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
doi: 10.1038/nature02218
-
Van Den Berg, B., Clemons, W. M. Jr., Collinson, I., Modis, Y., Hartmann, E., Harrison, S. C., et al. (2004). X-ray structure of a protein-conducting channel. Nature 427, 36-44. doi: 10.1038/nature02218.
-
(2004)
Nature
, vol.427
, pp. 36-44
-
-
Van Den Berg, B.1
Clemons Jr., W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
-
46
-
-
66249099231
-
A novel technology for the imaging of acidic prostate tumors by positron emission tomography
-
doi: 10.1158/0008-5472.CAN-08-3781
-
Vavere, A. L., Biddlecombe, G. B., Spees, W. M., Garbow, J. R., Wijesinghe, D., Andreev, O. A., et al. (2009). A novel technology for the imaging of acidic prostate tumors by positron emission tomography. Cancer Res. 69, 4510-4516. doi: 10.1158/0008-5472.CAN-08-3781.
-
(2009)
Cancer Res.
, vol.69
, pp. 4510-4516
-
-
Vavere, A.L.1
Biddlecombe, G.B.2
Spees, W.M.3
Garbow, J.R.4
Wijesinghe, D.5
Andreev, O.A.6
-
47
-
-
84876020428
-
Family of pH (low) insertion peptides for tumor targeting
-
doi: 10.1073/pnas.1303708110
-
Weerakkody, D., Moshnikova, A., Thakur, M. S., Moshnikova, V., Daniels, J., Engelman, D. M., et al. (2013). Family of pH (low) insertion peptides for tumor targeting. Proc. Natl. Acad. Sci. U.S.A. 110, 5834-5839. doi: 10.1073/pnas.1303708110.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 5834-5839
-
-
Weerakkody, D.1
Moshnikova, A.2
Thakur, M.S.3
Moshnikova, V.4
Daniels, J.5
Engelman, D.M.6
-
48
-
-
4143101547
-
The machinery of membrane protein assembly
-
doi: 10.1016/j.sbi.2004.07.003
-
White, S. H., and Von Heijne, G. (2004). The machinery of membrane protein assembly. Curr. Opin. Struct. Biol. 14, 397-404. doi: 10.1016/j.sbi.2004.07.003.
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 397-404
-
-
White, S.H.1
Von Heijne, G.2
-
49
-
-
84890936296
-
pH dependent transfer of nano-pores into membrane of cancer cells to induce apoptosis
-
doi: 10.1038/srep03560
-
Wijesinghe, D., Arachchige, M. C., Lu, A., Reshetnyak, Y. K., and Andreev, O. A. (2013). pH dependent transfer of nano-pores into membrane of cancer cells to induce apoptosis. Sci. Rep. 3:3560. doi: 10.1038/srep03560.
-
(2013)
Sci. Rep.
, vol.3
, pp. 3560
-
-
Wijesinghe, D.1
Arachchige, M.C.2
Lu, A.3
Reshetnyak, Y.K.4
Andreev, O.A.5
-
50
-
-
81855190867
-
Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide
-
doi: 10.1021/bi2009773
-
Wijesinghe, D., Engelman, D. M., Andreev, O. A., and Reshetnyak, Y. K. (2011). Tuning a polar molecule for selective cytoplasmic delivery by a pH (Low) insertion peptide. Biochemistry 50, 10215-10222. doi: 10.1021/bi2009773.
-
(2011)
Biochemistry
, vol.50
, pp. 10215-10222
-
-
Wijesinghe, D.1
Engelman, D.M.2
Andreev, O.A.3
Reshetnyak, Y.K.4
-
51
-
-
84872198010
-
pHLIP peptide targets nanogold particles to tumors
-
doi: 10.1073/pnas.1219665110
-
Yao, L., Daniels, J., Moshnikova, A., Kuznetsov, S., Ahmed, A., Engelman, D. M., et al. (2013a). pHLIP peptide targets nanogold particles to tumors. Proc. Natl. Acad. Sci. U.S.A. 110, 465-470. doi: 10.1073/pnas.1219665110.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 465-470
-
-
Yao, L.1
Daniels, J.2
Moshnikova, A.3
Kuznetsov, S.4
Ahmed, A.5
Engelman, D.M.6
-
52
-
-
84874933955
-
pHLIP(R)-mediated delivery of PEGylated liposomes to cancer cells
-
doi: 10.1016/j.jconrel.2013.01.037
-
Yao, L., Daniels, J., Wijesinghe, D., Andreev, O. A., and Reshetnyak, Y. K. (2013b). pHLIP(R)-mediated delivery of PEGylated liposomes to cancer cells. J. Control. Release 167, 228-237. doi: 10.1016/j.jconrel.2013.01.037.
-
(2013)
J. Control. Release
, vol.167
, pp. 228-237
-
-
Yao, L.1
Daniels, J.2
Wijesinghe, D.3
Andreev, O.A.4
Reshetnyak, Y.K.5
|