PH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 47, 2010, Pages 20246-20250

  An, Ming ^a   Wijesinghe, Dayanjali ^b   Andreev, Oleg A ^b   Reshetnyak, Yana K ^b   Engelman, Donald M ^a  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Cytoplasmic delivery; Drug delivery; Hydrophilic drugs; Targeted chemotherapy; Targeting acidity

Indexed keywords

1 PALMITOYL 2 OLEOYL SN GLYCERO 3 PHOSPHOCHOLINE; F ACTIN; PEPTIDE; PH LOW INSERTION PEPTIDE; PHALLOIDIN; PHOSPHORYLCHOLINE; RHODAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CARBOXY TERMINAL SEQUENCE; CELL CULTURE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DEPOLYMERIZATION; DISULFIDE BOND; DRUG DELIVERY SYSTEM; GENE INSERTION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 78650553199     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1014403107     Document Type: Article

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