The cytotoxic role of intermittent high glucose on apoptosis and cell viability in pancreatic beta cells

Journal of Diabetes Research

Volumn 2014, Issue , 2014, Pages

  Zhang, Zhen ^a   Li, Jing ^b   Yang, Lei ^c   Chen, Rongping ^a   Yang, Rui ^a   Zhang, Hua ^a   Cai, Dehong ^a   Chen, Hong ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGDONG MEDICAL UNIVERSITY   (China)

^c SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN D1; GLUCOSE; PROTEIN P21; PROTEIN P27; REACTIVE OXYGEN METABOLITE; S PHASE KINASE ASSOCIATED PROTEIN 2; XANTHINE OXIDASE; CCND1 PROTEIN, RAT; CDKN1A PROTEIN, RAT; CDKN1B PROTEIN, RAT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; S PHASE KINASE ASSOCIATED PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL LEVEL; CELL PROLIFERATION; CELL STRESS; CELL VIABILITY; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DOWN REGULATION; DRUG ANTAGONISM; DRUG POTENTIATION; ENZYMOLOGY; HYPERGLYCEMIA; METABOLISM; PATHOLOGY; RAT; TIME; UPREGULATION;

ANIMALS; APOPTOSIS; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOWN-REGULATION; G0 PHASE; GLUCOSE; HYPERGLYCEMIA; INSULIN-SECRETING CELLS; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES; S-PHASE KINASE-ASSOCIATED PROTEINS; TIME FACTORS; UP-REGULATION; XANTHINE OXIDASE;

EID: 84897533618     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2014/712781     Document Type: Article

References (38)

1. Donath M. Y., Ehses J. A., Maedler K., Schumann D. M., Ellingsgaard H., Eppler E., Reinecke M., Mechanisms of β -cell death in type 2 diabetes. Diabetes 2005 54 2 S108 S113 2-s2.0-33644747390 10.2337/diabetes.54.suppl-2.S108 (Pubitemid 43343338)
2. Prentki M., Nolan C. J., Islet β cell failure in type 2 diabetes. Journal of Clinical Investigation 2006 116 7 1802 1812 2-s2.0-33745863033 10.1172/JCI29103 (Pubitemid 44033300)
3. Rhodes C. J., Type 2 diabetes-a matter of β -cell life and death? Science 2005 307 5708 380 384 2-s2.0-12344323484 10.1126/science.1104345 (Pubitemid 40139973)
4. Butler A. E., Janson J., Bonner-Weir S., Ritzel R., Rizza R. A., Butler P. C., β -cell deficit and increased β -cell apoptosis in humans with type 2 diabetes. Diabetes 2003 52 1 102 110 2-s2.0-0037219411 10.2337/diabetes.52.1.102 (Pubitemid 36042113)
5. Yoon K. H., Ko S. H., Cho J. H., Lee J. M., Ahn Y. B., Song K. H., Yoo S. J., Kang M. I., Cha B. Y., Lee K. W., Son H. Y., Kang S. K., Kim H. S., Lee I. K., Bonner-Weir S., Selective β -cell loss and α -cell expansion in patients with type 2 diabetes mellitus in Korea. Journal of Clinical Endocrinology and Metabolism 2003 88 5 2300 2308 2-s2.0-0038707331 10.1210/jc.2002-020735 (Pubitemid 36549911)
6. UK Prospective Diabetes Study (UKPDS) Group, Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). The Lancet 1998 352 9131 837 853 2-s2.0-0032511583 10.1016/S0140-6736(98)07019-6 (Pubitemid 28416718)
7. Murata G. H., Duckworth W. C., Shah J. H., Wendel C. S., Hoffman R. M., Sources of glucose variability in insulin-treated type 2 diabetes: the Diabetes Outcomes in Veterans Study (DOVES). Clinical Endocrinology 2004 60 4 451 456 2-s2.0-1842633633 10.1111/j.1365-2265.2004.02001.x (Pubitemid 38482507)
8. Piconi L., Corgnali M., Da Ros R., Assaloni R., Piliego T., Ceriello A., The protective effect of rosuvastatin in human umbilical endothelial cells exposed to constant or intermittent high glucose. Journal of Diabetes and its Complications 2008 22 1 38 45 2-s2.0-37749030539 10.1016/j.jdiacomp.2007.03.004
9. Ceriello A., Ihnat M. A., 'Glycaemic variability': a new therapeutic challenge in diabetes and the critical care setting. Diabetic Medicine 2010 27 8 862 867 2-s2.0-77954790519 10.1111/j.1464-5491.2010.02967.x
10. Muggeo M., Zoppini G., Bonora E., Brun E., Bonadonna R. C., Moghetti P., Verlato G., Fasting plasma glucose variability predicts 10-year survival of type 2 diabetic patients: the Verona Diabetes Study. Diabetes Care 2000 23 1 45 50 2-s2.0-0033957393 (Pubitemid 30022893)
11. Kohnert K. D., Freyse E. J., Salzsieder E., Glycaemic variability and pancreatic β -cell dysfunction. Current Diabetes Reviews 2012 8 5 345 354 10.2174/157339912802083513
12. Hou Z. Q., Li H. L., Gao L., Pan L., Zhao J. J., Li G. W., Involvement of chronic stresses in rat islet and INS-1 cell glucotoxicityn induced by intermittent high glucose. Molecular and Cellular Endocrinology 2008 291 1-2 71 78 10.1016/j.mce.2008.03.004
13. Yesil P., Lammert E., Islet dynamics: a glimpse at beta cell proliferation. Histology and Histopathology 2008 23 7-9 883 895 2-s2.0-44449107712
14. Sheu M. L., Ho F. M., Yang R. S., Chao K. F., Lin W. W., Lin-Shiau S. Y., Liu S. H., High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway. Arteriosclerosis, Thrombosis, and Vascular Biology 2005 25 3 539 545 2-s2.0-14644425394 10.1161/01.ATV.0000155462.24263.e4 (Pubitemid 40315675)
15. Tamta H., Kalra S., Mukhopadhyay A. K., Biochemical characterization of some pyrazolopyrimidine-based inhibitors of xanthine oxidase. Biochemistry 2006 71 supplement 1 S49 S54 2-s2.0-33646188496 10.1134/S0006297906130086
16. Mwitari P. G., Ayeka P. A., Ondicho J., Matu E. N., Bii C. C., Antimicrobial activity and probable mechanisms of action of medicinal plants of Kenya: withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatus. PLOS ONE 2013 8 6 e65619 10.1371/journal.pone.0065619
17. Zhang T., Tan Y., Zhao R., Liu Z., DNA damage induced by oridonin involves cell cycle arrest at G2/M phase in human MCF-7 cells. Contemporary Oncology 2013 17 1 38 44
18. Shi X. L., Ren Y. Z., Wu J., Intermittent high glucose enhances apoptosis in INS-1 cells. Experimental Diabetes Research 2011 2011 2-s2.0-80052712251 10.1155/2011/754673 754673
19. Mohanty S., Spinas G. A., Maedler K., Zuellig R. A., Lehmann R., Donath M. Y., Trüb T., Niessen M., Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human β -cells from hyperglycemia-induced apoptosis. Experimental Cell Research 2005 303 1 68 78 2-s2.0-9644268058 10.1016/j.yexcr.2004.09.011 (Pubitemid 39575145)
20. Maedler K., Schulthess F. T., Bielman C., Berney T., Bonny C., Prentki M., Donath M. Y., Roduit R., Glucose and leptin induce apoptosis in human β -cells and impair glucose-stimulated insulin secretion through activation of c-Jun N-terminal kinases. FASEB Journal 2008 22 6 1905 1913 2-s2.0-44949143027 10.1096/fj.07-101824 (Pubitemid 351811467)
21. Li H., Télémaque S., Miller R. E., Marsh J. D., High glucose inhibits apoptosis induced by serum deprivation in vascular smooth muscle cells via upregulation of Bcl-2 and Bcl-xl. Diabetes 2005 54 2 540 545 2-s2.0-12744279316 10.2337/diabetes.54.2.540
22. Chen G., Chen Y., Chen H., Li L., Yao J., Jiang Q., Lin X., Wen J., Lin L., The effect of NF- B pathway on proliferation and apoptosis of human umbilical vein endothelial cells induced by intermittent high glucose. Molecular and Cellular Biochemistry 2011 347 1-2 127 133 2-s2.0-78651337702 10.1007/s11010-010-0620-5
23. Kim M., Chung H., Yoon C., Lee E., Kim T., Kim T., Kwon M., Lee S., Rhee B., Park J., Increase of INS-1 cell apoptosis under glucose fluctuation and the involvement of FOXO-SIRT pathway. Diabetes Research and Clinical Practice 2012 98 1 132 139 10.1016/j.diabres.2012.04.013
24. Sun L. Q., Chen Y. Y., Wang Li XJ X., Xue B., Qu L., Zhang T. T., Mu Y. M., Lu J. M., The protective effect of alpha lipoic acid on Schwann cells exposed to constant or intermittent high glucose. Biochemical Pharmacology 2012 84 7 961 973 10.1016/j.bcp.2012.07.005
25. Del Guerra S., Grupillo M., Masini M., Lupi R., Bugliani M., Torri S., Boggi U., Del Chiaro M., Vistoli F., Mosca F., Del Prato S., Marchetti P., Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose. Diabetes/Metabolism Research and Reviews 2007 23 3 234 238 2-s2.0-33947305767 10.1002/dmrr.680 (Pubitemid 46437850)
26. Gibbings S., Elkins N. D., Fitzgerald H., Tiao J., Weyman M. E., Shibao G., Fini M. A., Wright R. M., Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor- γ sumoylation, and HIF-1 α Journal of Biological Chemistry 2011 286 2 961 975 2-s2.0-78651409652 10.1074/jbc.M110.150847
27. Kushiyama A., Okubo H., Sakoda H., Kikuchi T., Fujishiro M., Sato H., Kushiyama S., Iwashita M., Nishimura F., Fukushima T., Nakatsu Y., Kamata H., Kawazu S., Higashi Y., Kurihara H., Asano T., Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development. Arteriosclerosis, Thrombosis, and Vascular Biology 2012 32 2 291 298 2-s2.0-84856228005 10.1161/ATVBAHA.111.234559
28. Miric D., Kisic B., Stolic R., Miric B., Mitic R., Janicijevic-Hudomal S., The role of xanthine oxidase in hemodialysis-induced oxidative injury: relationship with nutritional status. Oxidative Medicine and Cellular Longevity 2013 2013 8 245253 10.1155/2013/245253
29. Dor Y., Brown J., Martinez O. I., Melton D. A., Adult pancreatic β -cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004 429 6987 41 46 2-s2.0-2342510386 10.1038/nature02520 (Pubitemid 38620543)
30. Garcia-Ocaña A., Alonso L. C., Glucose mediated regulation of beta cell proliferation. The Open Endocrinology Journal 2010 4 55 65 10.2174/1874216501004010055
31. Bicknell K. A., Surry E. L., Brooks G., Targeting the cell cycle machinery for the treatment of cardiovascular disease. Journal of Pharmacy and Pharmacology 2003 55 5 571 591 2-s2.0-0038719694 10.1211/002235703765344487 (Pubitemid 36705569)
32. Cozar-Castellano I., Takane K. K., Bottino R., Balamurugan A. N., Stewart A. F., Induction of β -cell proliferation and retinoblastoma protein phosphorylation in rat and human islets using adenovirus-mediated transfer of cyclin-dependent kinase-4 and cyclin D1. Diabetes 2004 53 1 149 159 2-s2.0-0347990598 10.2337/diabetes.53.1.149 (Pubitemid 38044709)
33. Zhang X., Gaspard J. P., Mizukami Y., Li J., Graeme-Cook F., Chung D. C., Overexpression of cyclin D1 in pancreatic β -cells in vivo results in islet hyperplasia without hypoglycemia. Diabetes 2005 54 3 712 719 2-s2.0-14644422601 10.2337/diabetes.54.3.712 (Pubitemid 40322073)
34. Pines J., Cyclin-dependent kinase inhibitors: the age of crystals. Biochimica et Biophysica Acta-Reviews on Cancer 1997 1332 1 M39 M42 2-s2.0-0031055253 10.1016/S0304-419X(96)00042-X (Pubitemid 27112551)
35. Cozar-Castellano I., Weinstock M., Haught M., Velázquez-Garcia S., Sipula D., Stewart A. F., Evaluation of β -cell replication in mice transgenic for hepatocyte growth factor and placental lactogen: comprehensive characterization of the G1/S regulatory proteins reveals unique involvement of p21 cip. Diabetes 2006 55 1 70 77 2-s2.0-33644773614 10.2337/diabetes.55.1.70 (Pubitemid 43343300)
36. Karnik S. K., Hughes C. M., Gu X., Rozenblatt-Rosen O., McLean G. W., Xiong Y., Meyerson M., Kim S. K., Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proceedings of the National Academy of Sciences of the United States of America 2005 102 41 14659 14664 2-s2.0-26844548626 10.1073/pnas.0503484102 (Pubitemid 41457112)
37. Carrano A. C., Eytan E., Hershko A., Pagano M., SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nature Cell Biology 1999 1 4 193 199 2-s2.0-0033176887 (Pubitemid 129500937)
38. Bornstein G., Bloom J., Sitry-Shevah D., Nakayama K., Pagano M., Hershko A., Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase. Journal of Biological Chemistry 2003 278 28 25752 25757 2-s2.0-0038152755 10.1074/jbc.M301774200 (Pubitemid 36835332)