Transition state in DNA polymerase β Catalysis: Rate-Limiting chemistry altered by base-pair configuration

Biochemistry

Volumn 53, Issue 11, 2014, Pages 1842-1848

  Oertell, Keriann ^a   Chamberlain, Brian T ^a   Wu, Yue ^a   Ferri, Elena ^a   Kashemirov, Boris A ^a   Beard, William A ^b   Wilson, Samuel H ^b   McKenna, Charles E ^a   Goodman, Myron F ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RATE CONSTANTS;

CATALYTIC RATES; CONFORMATIONAL CHANGE; DNA POLYMERASE; KINETICS STUDIES; LEAVING GROUPS; LINEAR FREE ENERGY RELATIONSHIPS; NEGATIVE SLOPE; TRANSITION-STATE;

BROMINE;

DNA DIRECTED DNA POLYMERASE BETA; THYMIDINE TRIPHOSPHATE;

ARTICLE; BASE PAIRING; CATALYSIS; CHIRALITY; CONFORMATIONAL TRANSITION; DIASTEREOISOMER; HYDROGEN BOND; PHASE TRANSITION; PKA; PRIORITY JOURNAL; STATIC ELECTRICITY; STEADY STATE;

BASE PAIRING; CATALYSIS; DNA DAMAGE; DNA POLYMERASE BETA; ENZYME STABILITY; HYDROGEN BONDING; PROTEIN CONFORMATION;

EID: 84897040751     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500101z     Document Type: Article

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