Stereospecific Formation of a Ternary Complex of (S)-α,β-Fluoromethylene-dATP with DNA Pol β

ChemBioChem

Volumn 13, Issue 4, 2012, Pages 528-530

  Chamberlain, Brian T ^b   Batra, Vinod K ^a   Beard, William A ^a   Kadina, Anastasia P ^b   Shock, David D ^a   Kashemirov, Boris A ^b   Mckenna, Charles E ^b   Goodman, Myron F ^b   Wilson, Samuel H ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Enzymes; Fluorine; Inhibitors; Nucleotides

Indexed keywords

ALPHA BETA FLUOROMETHYLENE DEOXYADENOSINE TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DNA SYNTHESIS; ENZYME BINDING; FLUORINE NUCLEAR MAGNETIC RESONANCE; MOLECULAR DOCKING; PRIORITY JOURNAL; STEREOISOMERISM; STEREOSPECIFICITY; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DEOXYADENINE NUCLEOTIDES; DNA POLYMERASE BETA; MODELS, MOLECULAR; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 84857512594     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201100738     Document Type: Article

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