Mismatched and matched dNTP incorporation by DNA polymerase β proceed via analogous kinetic pathways

Biochemistry

Volumn 47, Issue 37, 2008, Pages 9718-9727

  Roettger, Michelle P ^a   Bakhtina, Marina ^a   Tsai, Ming Daw ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSTS; CHLORINE COMPOUNDS; DNA; EMISSION SPECTROSCOPY; ENZYMES; FLUORESCENCE; GENES; LUMINESCENCE; NUCLEIC ACIDS; ORGANIC ACIDS; PROTEINS;

BIPHASIC; CHEMICAL TRANSITION; DNA POLYMERASES; ENHANCED EFFICIENCY; ERROR-PRONE; FLUORESCENCE ASSAYS; FLUORESCENCE EMISSIONS; FLUORESCENCE TRANSITIONS; KINETIC EVALUATIONS; KINETIC PATHWAYS; POLYMERASE FIDELITY; STEADY-STATE FLUORESCENCE; STOPPED-FLOW; SUB DOMAINS; TERNARY COMPLEX FORMATION; TERNARY COMPLEXES; WILD-TYPE;

LIGHT EMISSION;

DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; DNA DIRECTED DNA POLYMERASE BETA;

ARTICLE; BASE MISPAIRING; BASE PAIRING; FLUORESCENCE ANALYSIS; FLUORESCENCE SPECTROSCOPY; MOLECULAR MECHANICS; PRIORITY JOURNAL; STEADY STATE; WILD TYPE;

BASE PAIR MISMATCH; DEOXYRIBONUCLEOTIDES; DNA POLYMERASE BETA; DNA PRIMERS; KINETICS; NUCLEIC ACID CONFORMATION; SPECTROMETRY, FLUORESCENCE;

EID: 51849149950     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800689d     Document Type: Article

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