LPS-induced systemic inflammation is more severe in P2Y12 null mice

Journal of Leukocyte Biology

Volumn 95, Issue 2, 2014, Pages 313-323

  Liverani, Elisabetta ^a   Rico, Mario C ^a   Yaratha, Laxmikausthubha ^a   Tsygankov, Alexander Y ^a   Kilpatrick, Laurie E ^a   Kunapuli, Satya P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

P2Y receptor antagonism; Thienopyridine platelets

Indexed keywords

CLOPIDOGREL; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PURINERGIC P2Y12 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; P2RY12 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; INFLAMMATION; LEUKOCYTE; LOADING DRUG DOSE; MAINTENANCE DRUG DOSE; MOUSE; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPLEEN LYMPHOCYTE; SYSTEMIC DISEASE; THROMBOCYTE COUNT; ANIMAL; BLOOD; BODY WEIGHT; BONE MARROW; C57BL MOUSE; DRUG EFFECT; IMMUNOLOGY; KNOCKOUT MOUSE; LEUKOCYTE COUNT; LUNG INJURY; MALE; METABOLISM; ORGAN SIZE; P2Y RECEPTOR ANTAGONISM; PATHOLOGY; SPLENOMEGALY; SURVIVAL; THIENOPYRIDINE PLATELETS;

P2Y RECEPTOR ANTAGONISM; THIENOPYRIDINE PLATELETS;

ANIMALS; BODY WEIGHT; BONE MARROW; CYTOKINES; INFLAMMATION; LEUKOCYTE COUNT; LEUKOCYTES; LIPOPOLYSACCHARIDES; LUNG INJURY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; RECEPTORS, PURINERGIC P2Y12; SPLENOMEGALY; SURVIVAL ANALYSIS;

EID: 84897022751     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.1012518     Document Type: Article

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