-
1
-
-
48249126806
-
The prion's elusive reason for being
-
PMID:18558863
-
Aguzzi A, Baumann F, Bremer J. The prion's elusive reason for being. Annu Rev Neurosci 2008; 31:439- 77; PMID:18558863; http://dx.doi.org/10.1146/ annurev.neuro.31.060407.125620
-
(2008)
Annu Rev Neurosci
, vol.31
, pp. 439-477
-
-
Aguzzi, A.1
Baumann, F.2
Bremer, J.3
-
2
-
-
82455164097
-
Infectious prion protein alters manganese transport and neurotoxicity in a cell culture model of prion disease
-
PMID:21871919
-
Martin DP, Anantharam V, Jin H, Witte T, Houk R, Kanthasamy A, Kanthasamy AG. Infectious prion protein alters manganese transport and neurotoxicity in a cell culture model of prion disease. Neurotoxicology 2011; 32:554-62; PMID:21871919; http://dx.doi.org/10.1016/j.neuro.2011.07.008
-
(2011)
Neurotoxicology
, vol.32
, pp. 554-562
-
-
Martin, D.P.1
Anantharam, V.2
Jin, H.3
Witte, T.4
Houk, R.5
Kanthasamy, A.6
Kanthasamy, A.G.7
-
3
-
-
0030478022
-
Molecular biology and pathogenesis of prion diseases
-
PMID:9009832
-
Prusiner SB. Molecular biology and pathogenesis of prion diseases. Trends Biochem Sci 1996; 21:482- 7; PMID:9009832; http://dx.doi.org/10.1016/ S0968-0004(96)10063-3
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 482-487
-
-
Prusiner, S.B.1
-
4
-
-
56049121173
-
Opposing roles of prion protein in oxidative stressand ER stress-induced apoptotic signaling
-
PMID:18835352
-
Anantharam V, Kanthasamy A, Choi CJ, Martin DP, Latchoumycandane C, Richt JA, Kanthasamy AG. Opposing roles of prion protein in oxidative stressand ER stress-induced apoptotic signaling. Free Radic Biol Med 2008; 45:1530-41; PMID:18835352; http:// dx.doi.org/10.1016/j.freeradbiomed.2008.08.028
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1530-1541
-
-
Anantharam, V.1
Kanthasamy, A.2
Choi, C.J.3
Martin, D.P.4
Latchoumycandane, C.5
Richt, J.A.6
Kanthasamy, A.G.7
-
5
-
-
0027997387
-
Prion protein is necessary for normal synaptic function
-
PMID:8035877
-
Collinge J, Whittington MA, Sidle KC, Smith CJ, Palmer MS, Clarke AR, Jefferys JG. Prion protein is necessary for normal synaptic function. Nature 1994; 370:295-7; PMID:8035877; http://dx.doi. org/10.1038/370295a0
-
(1994)
Nature
, vol.370
, pp. 295-297
-
-
Collinge, J.1
Whittington, M.A.2
Sidle, K.C.3
Smith, C.J.4
Palmer, M.S.5
Clarke, A.R.6
Jefferys, J.G.7
-
6
-
-
84867235684
-
Effect of divalent metals on the neuronal proteasomal system, prion protein ubiquitination and aggregation
-
PMID:22995398
-
Kanthasamy AG, Choi C, Jin H, Harischandra DS, Anantharam V, Kanthasamy A. Effect of divalent metals on the neuronal proteasomal system, prion protein ubiquitination and aggregation. Toxicol Lett 2012; 214:288-95; PMID:22995398; http://dx.doi. org/10.1016/j.toxlet.2012.09.008
-
(2012)
Toxicol Lett
, vol.214
, pp. 288-295
-
-
Kanthasamy, A.G.1
Choi, C.2
Jin, H.3
Harischandra, D.S.4
Anantharam, V.5
Kanthasamy, A.6
-
7
-
-
33747164172
-
Interaction of metals with prion protein: Possible role of divalent cations in the pathogenesis of prion diseases
-
PMID:16860868
-
Choi CJ, Kanthasamy A, Anantharam V, Kanthasamy AG. Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases. Neurotoxicology 2006; 27:777-87; PMID:16860868; http://dx.doi.org/10.1016/j. neuro.2006.06.004
-
(2006)
Neurotoxicology
, vol.27
, pp. 777-787
-
-
Choi, C.J.1
Kanthasamy, A.2
Anantharam, V.3
Kanthasamy, A.G.4
-
8
-
-
0027491308
-
Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti- PrP antibodies
-
PMID:7902565
-
Prusiner SB, Groth D, Serban A, Koehler R, Foster D, Torchia M, Burton D, Yang SL, DeArmond SJ. Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti- PrP antibodies. Proc Natl Acad Sci U S A 1993; 90:10608-12; PMID:7902565; http://dx.doi. org/10.1073/pnas.90.22. 10608
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 10608-10612
-
-
Prusiner, S.B.1
Groth, D.2
Serban, A.3
Koehler, R.4
Foster, D.5
Torchia, M.6
Burton, D.7
Yang, S.L.8
Dearmond, S.J.9
-
9
-
-
0033826082
-
Evidence for oxidative stress in experimental prion disease
-
PMID:10964599
-
Guentchev M, Voigtländer T, Haberler C, Groschup MH, Budka H. Evidence for oxidative stress in experimental prion disease. Neurobiol Dis 2000; 7:270- 3; PMID:10964599; http://dx.doi.org/10.1006/ nbdi.2000.0290
-
(2000)
Neurobiol Dis
, vol.7
, pp. 270-273
-
-
Guentchev, M.1
Voigtländer, T.2
Haberler, C.3
Groschup, M.H.4
Budka, H.5
-
10
-
-
0035033411
-
Oxidative stress and neurodegeneration in prion diseases
-
PMID:11795509
-
Kim JI, Choi SI, Kim NH, Jin JK, Choi EK, Carp RI, Kim YS. Oxidative stress and neurodegeneration in prion diseases. Ann N Y Acad Sci 2001; 928:182-6; PMID:11795509; http://dx.doi. org/10.1111/j.1749-6632.2001.tb05648.x
-
(2001)
Ann N y Acad Sci
, vol.928
, pp. 182-186
-
-
Kim, J.I.1
Choi, S.I.2
Kim, N.H.3
Jin, J.K.4
Choi, E.K.5
Carp, R.I.6
Kim, Y.S.7
-
11
-
-
30944453898
-
Neurodegeneration and oxidative stress: Prion disease results from loss of antioxidant defence
-
PMID:16416388
-
Brown DR. Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 2005; 43:229-43; PMID:16416388
-
(2005)
Folia Neuropathol
, vol.43
, pp. 229-243
-
-
Brown, D.R.1
-
12
-
-
77956228435
-
Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: Relevance to oxidative stress and neuroinflammation in Parkinson's disease
-
PMID:20005250
-
Kanthasamy A, Jin H, Mehrotra S, Mishra R, Kanthasamy A, Rana A. Novel cell death signaling pathways in neurotoxicity models of dopaminergic degeneration: relevance to oxidative stress and neuroinflammation in Parkinson's disease. Neurotoxicology 2010; 31:555-61; PMID:20005250; http://dx.doi.org/10. 1016/j.neuro.2009.12.003
-
(2010)
Neurotoxicology
, vol.31
, pp. 555-561
-
-
Kanthasamy, A.1
Jin, H.2
Mehrotra, S.3
Mishra, R.4
Kanthasamy, A.5
Rana, A.6
-
13
-
-
23344444562
-
Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells
-
PMID:15961393
-
Kaul S, Anantharam V, Yang Y, Choi CJ, Kanthasamy A, Kanthasamy AG. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells. J Biol Chem 2005; 280:28721-30; PMID:15961393; http:// dx.doi.org/10.1074/jbc.M501092200
-
(2005)
J Biol Chem
, vol.280
, pp. 28721-28730
-
-
Kaul, S.1
Anantharam, V.2
Yang, Y.3
Choi, C.J.4
Kanthasamy, A.5
Kanthasamy, A.G.6
-
14
-
-
84861202134
-
Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells
-
PMID:22445524
-
Lin M, Chandramani-Shivalingappa P, Jin H, Ghosh A, Anantharam V, Ali S, Kanthasamy AG, Kanthasamy A. Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells. Neuroscience 2012; 210:308- 32; PMID:22445524; http://dx.doi.org/10.1016/j. neuroscience.2012.03.004
-
(2012)
Neuroscience
, vol.210
, pp. 308-332
-
-
Lin, M.1
Chandramani-Shivalingappa, P.2
Jin, H.3
Ghosh, A.4
Anantharam, V.5
Ali, S.6
Kanthasamy, A.G.7
Kanthasamy, A.8
-
15
-
-
82455199222
-
Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCβ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model
-
PMID:21801747
-
Saminathan H, Asaithambi A, Anantharam V, Kanthasamy AG, Kanthasamy A. Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCβ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model. Neurotoxicology 2011; 32:567- 77; PMID:21801747; http://dx.doi.org/10.1016/j. neuro.2011.06.009
-
(2011)
Neurotoxicology
, vol.32
, pp. 567-577
-
-
Saminathan, H.1
Asaithambi, A.2
Anantharam, V.3
Kanthasamy, A.G.4
Kanthasamy, A.5
-
16
-
-
84866290238
-
Organotypic brain slice cultures of adult transgenic P301S mice-A model for tauopathy studies
-
PMID:22984603
-
Mewes A, Franke H, Singer D. Organotypic brain slice cultures of adult transgenic P301S mice-a model for tauopathy studies. PLoS One 2012; 7:e45017; PMID:22984603; http://dx.doi.org/10.1371/journal. pone.0045017
-
(2012)
PLoS One
, vol.7
-
-
Mewes, A.1
Franke, H.2
Singer, D.3
-
17
-
-
33947653114
-
Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics
-
PMID:18615151
-
Cho S, Wood A, Bowlby MR. Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics. Curr Neuropharmacol 2007; 5:19-33; PMID:18615151; http://dx.doi. org/10.2174/ 157015907780077105
-
(2007)
Curr Neuropharmacol
, vol.5
, pp. 19-33
-
-
Cho, S.1
Wood, A.2
Bowlby, M.R.3
-
18
-
-
37549043842
-
A versatile prion replication assay in organotypic brain slices
-
PMID:18066056
-
Falsig J, Julius C, Margalith I, Schwarz P, Heppner FL, Aguzzi A. A versatile prion replication assay in organotypic brain slices. Nat Neurosci 2008; 11:109- 17; PMID:18066056; http://dx.doi.org/10.1038/ nn2028
-
(2008)
Nat Neurosci
, vol.11
, pp. 109-117
-
-
Falsig, J.1
Julius, C.2
Margalith, I.3
Schwarz, P.4
Heppner, F.L.5
Aguzzi, A.6
-
19
-
-
84870843645
-
Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures
-
PMID:23133383
-
Falsig J, Sonati T, Herrmann US, Saban D, Li B, Arroyo K, Ballmer B, Liberski PP, Aguzzi A. Prion pathogenesis is faithfully reproduced in cerebellar organotypic slice cultures. PLoS Pathog 2012; 8:e1002985; PMID:23133383; http://dx.doi. org/10.1371/journal.ppat.1002985
-
(2012)
PLoS Pathog
, vol.8
-
-
Falsig, J.1
Sonati, T.2
Herrmann, U.S.3
Saban, D.4
Li, B.5
Arroyo, K.6
Ballmer, B.7
Liberski, P.P.8
Aguzzi, A.9
-
20
-
-
0020490156
-
Identification of a protein that purifies with the scrapie prion
-
PMID:6815801
-
Bolton DC, McKinley MP, Prusiner SB. Identification of a protein that purifies with the scrapie prion. Science 1982; 218:1309-11; PMID:6815801; http:// dx.doi.org/10.1126/science.6815801
-
(1982)
Science
, vol.218
, pp. 1309-1311
-
-
Bolton, D.C.1
McKinley, M.P.2
Prusiner, S.B.3
-
21
-
-
57549096688
-
The POM monoclonals: A comprehensive set of antibodies to non-overlapping prion protein epitopes
-
PMID:19060956
-
Polymenidou M, Moos R, Scott M, Sigurdson C, Shi YZ, Yajima B, Hafner-Bratkovic I, Jerala R, Hornemann S, Wuthrich K, et al. The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes. PLoS One 2008; 3:e3872; PMID:19060956; http://dx.doi. org/10.1371/journal.pone.0003872
-
(2008)
PLoS One
, vol.3
-
-
Polymenidou, M.1
Moos, R.2
Scott, M.3
Sigurdson, C.4
Shi, Y.Z.5
Yajima, B.6
Hafner-Bratkovic, I.7
Jerala, R.8
Hornemann, S.9
Wuthrich, K.10
-
22
-
-
80053226172
-
Spongiform encephalopathy in transgenic mice expressing a point mutation in the ?2-?2 loop of the prion protein
-
PMID:21957246
-
Sigurdson CJ, Joshi-Barr S, Bett C, Winson O, Manco G, Schwarz P, Rülicke T, Nilsson KP, Margalith I, Raeber A, et al. Spongiform encephalopathy in transgenic mice expressing a point mutation in the ?2-?2 loop of the prion protein. J Neurosci 2011; 31:13840-7; PMID:21957246; http://dx.doi. org/10.1523/JNEUROSCI.3504-11.2011
-
(2011)
J Neurosci
, vol.31
, pp. 13840-13847
-
-
Sigurdson, C.J.1
Joshi-Barr, S.2
Bett, C.3
Winson, O.4
Manco, G.5
Schwarz, P.6
Rülicke, T.7
Nilsson, K.P.8
Margalith, I.9
Raeber, A.10
-
23
-
-
79957606079
-
Transcriptional regulation of proapoptotic protein kinase Cdelta: Implications for oxidative stress-induced neuronal cell death
-
PMID:21467032
-
Jin H, Kanthasamy A, Anantharam V, Rana A, Kanthasamy AG. Transcriptional regulation of proapoptotic protein kinase Cdelta: implications for oxidative stress-induced neuronal cell death. J Biol Chem 2011; 286:19840-59; PMID:21467032; http:// dx.doi.org/10.1074/jbc.M110.203687
-
(2011)
J Biol Chem
, vol.286
, pp. 19840-19859
-
-
Jin, H.1
Kanthasamy, A.2
Anantharam, V.3
Rana, A.4
Kanthasamy, A.G.5
-
24
-
-
84862208552
-
Proteolytic activation of proapoptotic kinase protein kinase C by tumor necrosis factor death receptor signaling in dopaminergic neurons during neuroinflammation
-
PMID:22540228
-
Gordon R, Anantharam V, Kanthasamy AG, Kanthasamy A. Proteolytic activation of proapoptotic kinase protein kinase C? by tumor necrosis factor ? death receptor signaling in dopaminergic neurons during neuroinflammation. J Neuroinflammation 2012; 9:82; PMID:22540228; http://dx.doi. org/10.1186/1742- 2094-9-82
-
(2012)
J Neuroinflammation
, vol.9
, pp. 82
-
-
Gordon, R.1
Anantharam, V.2
Kanthasamy, A.G.3
Kanthasamy, A.4
-
25
-
-
1342305460
-
Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: Implications for oxidative stress and environmental factors in Parkinson's disease
-
PMID:15033812
-
Kanthasamy AG, Kitazawa M, Kaul S, Yang Y, Lahiri DK, Anantharam V, Kanthasamy A. Proteolytic activation of proapoptotic kinase PKCdelta is regulated by overexpression of Bcl-2: implications for oxidative stress and environmental factors in Parkinson's disease. Ann N Y Acad Sci 2003; 1010:683-6; PMID:15033812; http://dx.doi.org/10.1196/ annals.1299.125
-
(2003)
Ann N y Acad Sci
, vol.1010
, pp. 683-686
-
-
Kanthasamy, A.G.1
Kitazawa, M.2
Kaul, S.3
Yang, Y.4
Lahiri, D.K.5
Anantharam, V.6
Kanthasamy, A.7
-
26
-
-
53249095492
-
Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease
-
PMID:18703134
-
Pamplona R, Naudí A, Gavín R, Pastrana MA, Sajnani G, Ilieva EV, Del Río JA, Portero-Otín M, Ferrer I, Requena JR. Increased oxidation, glycoxidation, and lipoxidation of brain proteins in prion disease. Free Radic Biol Med 2008; 45:1159-66; PMID:18703134; http://dx.doi.org/10.1016/j. freeradbiomed.2008.07.009
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 1159-1166
-
-
Pamplona, R.1
Naudí, A.2
Gavín, R.3
Pastrana, M.A.4
Sajnani, G.5
Ilieva, E.V.6
Del Río, J.A.7
Portero-Otín, M.8
Ferrer, I.9
Requena, J.R.10
-
27
-
-
33749139691
-
Oxidation, glycoxidation, lipoxidation, nitration, and responses to oxidative stress in the cerebral cortex in Creutzfeldt-Jakob disease
-
PMID:16310893
-
Freixes M, Rodríguez A, Dalfó E, Ferrer I. Oxidation, glycoxidation, lipoxidation, nitration, and responses to oxidative stress in the cerebral cortex in Creutzfeldt-Jakob disease. Neurobiol Aging 2006; 27:1807-15; PMID:16310893; http://dx.doi. org/10.1016/j.neurobiolaging.2005.10.006
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1807-1815
-
-
Freixes, M.1
Rodríguez, A.2
Dalfó, E.3
Ferrer, I.4
-
28
-
-
84882261910
-
Cellular prion protein (PrPC) of the neuron cell transformed to a PK-resistant protein under oxidative stress, comprising main mitochondrial damage in prion diseases
-
PMID:23715697
-
Yuan F, Yang L, Zhang Z, Wu W, Zhou X, Yin X, Zhao D. Cellular prion protein (PrPC) of the neuron cell transformed to a PK-resistant protein under oxidative stress, comprising main mitochondrial damage in prion diseases. J Mol Neurosci 2013; 51:219-24; PMID:23715697; http://dx.doi.org/10.1007/ s12031-013-0008-6
-
(2013)
J Mol Neurosci
, vol.51
, pp. 219-224
-
-
Yuan, F.1
Yang, L.2
Zhang, Z.3
Wu, W.4
Zhou, X.5
Yin, X.6
Zhao, D.7
-
29
-
-
84903301367
-
Mitochondriatargeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes
-
PMID:24060637
-
Jin H, Kanthasamy A, Ghosh A, Anantharam V, Kalyanaraman B, Kanthasamy AG. Mitochondriatargeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes. Biochim Biophys Acta 2013; PMID:24060637; http://dx.doi. org/10.1016/j.bbadis.2013.09.007
-
(2013)
Biochim Biophys Acta
-
-
Jin, H.1
Kanthasamy, A.2
Ghosh, A.3
Anantharam, V.4
Kalyanaraman, B.5
Kanthasamy, A.G.6
-
30
-
-
80855132749
-
Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease
-
PMID:21846476
-
Latchoumycandane C, Anantharam V, Jin H, Kanthasamy A, Kanthasamy A. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease. Toxicol Appl Pharmacol 2011; 256:314-23; PMID:21846476; http://dx.doi.org/10.1016/j.taap.2011.07.021
-
(2011)
Toxicol Appl Pharmacol
, vol.256
, pp. 314-323
-
-
Latchoumycandane, C.1
Anantharam, V.2
Jin, H.3
Kanthasamy, A.4
Kanthasamy, A.5
-
31
-
-
0028145277
-
Tyrosine phosphorylation of protein kinase C-delta in response to its activation
-
PMID:7507923
-
Li W, Mischak H, Yu JC, Wang LM, Mushinski JF, Heidaran MA, Pierce JH. Tyrosine phosphorylation of protein kinase C-delta in response to its activation. J Biol Chem 1994; 269:2349-52; PMID:7507923
-
(1994)
J Biol Chem
, vol.269
, pp. 2349-2352
-
-
Li, W.1
Mischak, H.2
Yu, J.C.3
Wang, L.M.4
Mushinski, J.F.5
Heidaran, M.A.6
Pierce, J.H.7
-
32
-
-
0032566691
-
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
-
PMID:9748166
-
Le Good JA, Ziegler WH, Parekh DB, Alessi DR, Cohen P, Parker PJ. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science 1998; 281:2042- 5; PMID:9748166; http://dx.doi.org/10.1126/ science.281.5385.2042
-
(1998)
Science
, vol.281
, pp. 2042-2045
-
-
Le Good, J.A.1
Ziegler, W.H.2
Parekh, D.B.3
Alessi, D.R.4
Cohen, P.5
Parker, P.J.6
-
33
-
-
0032989424
-
Neuropathological study of cerebellar degeneration in prion disease
-
PMID:19519645
-
Yang Q, Hashizume Y, Yoshida M, Wang Y. Neuropathological study of cerebellar degeneration in prion disease. Neuropathology 1999; 19:33-9; PMID:19519645; http://dx.doi. org/10.1046/j.1440-1789.1999.00212.x
-
(1999)
Neuropathology
, vol.19
, pp. 33-39
-
-
Yang, Q.1
Hashizume, Y.2
Yoshida, M.3
Wang, Y.4
-
34
-
-
20444499045
-
Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection
-
PMID:15932590
-
Carimalo J, Cronier S, Petit G, Peyrin JM, Boukhtouche F, Arbez N, Lemaigre-Dubreuil Y, Brugg B, Miquel MC. Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection. Eur J Neurosci 2005; 21:2311-9; PMID:15932590; http:// dx.doi.org/10.1111/j.1460-9568.2005.04080.x
-
(2005)
Eur J Neurosci
, vol.21
, pp. 2311-2319
-
-
Carimalo, J.1
Cronier, S.2
Petit, G.3
Peyrin, J.M.4
Boukhtouche, F.5
Arbez, N.6
Lemaigre-Dubreuil, Y.7
Brugg, B.8
Miquel, M.C.9
-
35
-
-
34547868484
-
Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein
-
PMID:17573907
-
Bourteele S, Oesterle K, Weinzierl AO, Paxian S, Riemann M, Schmid RM, Planz O. Alteration of NF-kappaB activity leads to mitochondrial apoptosis after infection with pathological prion protein. Cell Microbiol 2007; 9:2202-17; PMID:17573907; http://dx.doi.org/10.1111/j.1462-5822.2007.00950.x
-
(2007)
Cell Microbiol
, vol.9
, pp. 2202-2217
-
-
Bourteele, S.1
Oesterle, K.2
Weinzierl, A.O.3
Paxian, S.4
Riemann, M.5
Schmid, R.M.6
Planz, O.7
-
36
-
-
33748857338
-
Pathogenesis of prion diseases: Current status and future outlook
-
PMID:16980938
-
Aguzzi A, Heikenwalder M. Pathogenesis of prion diseases: current status and future outlook. Nat Rev Microbiol 2006; 4:765-75; PMID:16980938; http:// dx.doi.org/10.1038/nrmicro1492
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 765-775
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
37
-
-
83155167557
-
Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters
-
PMID:22174765
-
Bessen RA, Robinson CJ, Seelig DM, Watschke CP, Lowe D, Shearin H, Martinka S, Babcock AM. Transmission of chronic wasting disease identifies a prion strain causing cachexia and heart infection in hamsters. PLoS One 2011; 6:e28026; PMID:22174765; http://dx.doi.org/10.1371/journal. pone.0028026
-
(2011)
PLoS One
, vol.6
-
-
Bessen, R.A.1
Robinson, C.J.2
Seelig, D.M.3
Watschke, C.P.4
Lowe, D.5
Shearin, H.6
Martinka, S.7
Babcock, A.M.8
-
38
-
-
53549095695
-
Cell-free propagation of prion strains
-
PMID:18800058
-
Castilla J, Morales R, Saá P, Barria M, Gambetti P, Soto C. Cell-free propagation of prion strains. EMBO J 2008; 27:2557-66; PMID:18800058; http://dx.doi. org/10.1038/emboj.2008.181
-
(2008)
EMBO J
, vol.27
, pp. 2557-2566
-
-
Castilla, J.1
Morales, R.2
Saá, P.3
Barria, M.4
Gambetti, P.5
Soto, C.6
-
39
-
-
0034856144
-
Gerstmann- Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: A review of these less common human transmissible spongiform encephalopathies
-
PMID:11535002
-
Collins S, McLean CA, Masters CL. Gerstmann- Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies. J Clin Neurosci 2001; 8:387-97; PMID:11535002; http:// dx.doi.org/10.1054/jocn.2001.0919
-
(2001)
J Clin Neurosci
, vol.8
, pp. 387-397
-
-
Collins, S.1
McLean, C.A.2
Masters, C.L.3
-
40
-
-
56049100019
-
Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse
-
PMID:18716327
-
O'Shea M, Maytham EG, Linehan JM, Brandner S, Collinge J, Lloyd SE. Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse. Genetics 2008; 180:559-66; PMID:18716327; http://dx.doi.org/10. 1534/ genetics.108.090894
-
(2008)
Genetics
, vol.180
, pp. 559-566
-
-
O'Shea, M.1
Maytham, E.G.2
Linehan, J.M.3
Brandner, S.4
Collinge, J.5
Lloyd, S.E.6
-
41
-
-
34548101125
-
Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease
-
PMID:17565007
-
Zhang D, Anantharam V, Kanthasamy A, Kanthasamy AG. Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease. J Pharmacol Exp Ther 2007; 322:913-22; PMID:17565007; http://dx.doi.org/10.1124/jpet.107.124669
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 913-922
-
-
Zhang, D.1
Anantharam, V.2
Kanthasamy, A.3
Kanthasamy, A.G.4
-
42
-
-
42049098068
-
The prion organotypic slice culture assay-POSCA
-
PMID:18388937
-
Falsig J, Aguzzi A. The prion organotypic slice culture assay-POSCA. Nat Protoc 2008; 3:555- 62; PMID:18388937; http://dx.doi.org/10.1038/ nprot.2008.13
-
(2008)
Nat Protoc
, vol.3
, pp. 555-562
-
-
Falsig, J.1
Aguzzi, A.2
-
43
-
-
0142200985
-
Role of proteolytic activation of protein kinase Cdelta in oxidative stressinduced apoptosis
-
PMID:14580317
-
Kanthasamy AG, Kitazawa M, Kanthasamy A, Anantharam V. Role of proteolytic activation of protein kinase Cdelta in oxidative stressinduced apoptosis. Antioxid Redox Signal 2003; 5:609-20; PMID:14580317; http://dx.doi. org/10.1089/152308603770310275
-
(2003)
Antioxid Redox Signal
, vol.5
, pp. 609-620
-
-
Kanthasamy, A.G.1
Kitazawa, M.2
Kanthasamy, A.3
Anantharam, V.4
-
44
-
-
79951536222
-
β-Synuclein negatively regulates protein kinase C expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity
-
PMID:21307242
-
Jin H, Kanthasamy A, Ghosh A, Yang Y, Anantharam V, Kanthasamy AG. β-Synuclein negatively regulates protein kinase C? expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity. J Neurosci 2011; 31:2035- 51; PMID:21307242; http://dx.doi.org/10. 1523/ JNEUROSCI.5634-10.2011
-
(2011)
J Neurosci
, vol.31
, pp. 2035-2051
-
-
Jin, H.1
Kanthasamy, A.2
Ghosh, A.3
Yang, Y.4
Anantharam, V.5
Kanthasamy, A.G.6
-
45
-
-
84879998438
-
Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection
-
PMID:23580200
-
Sinclair L, Lewis V, Collins SJ, Haigh CL. Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection. Dis Model Mech 2013; 6:952-63; PMID:23580200; http:// dx.doi.org/10.1242/dmm.010678
-
(2013)
Dis Model Mech
, vol.6
, pp. 952-963
-
-
Sinclair, L.1
Lewis, V.2
Collins, S.J.3
Haigh, C.L.4
-
46
-
-
84883742582
-
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein
-
PMID:23903654
-
Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, et al. The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature 2013; 501:102-6; PMID:23903654; http:// dx.doi.org/10.1038/nature12402
-
(2013)
Nature
, vol.501
, pp. 102-106
-
-
Sonati, T.1
Reimann, R.R.2
Falsig, J.3
Baral, P.K.4
O'Connor, T.5
Hornemann, S.6
Yaganoglu, S.7
Li, B.8
Herrmann, U.S.9
Wieland, B.10
-
47
-
-
0036947279
-
Protein kinase C delta (PKC delta): Activation mechanisms and functions
-
PMID:12473183
-
Kikkawa U, Matsuzaki H, Yamamoto T. Protein kinase C delta (PKC delta): activation mechanisms and functions. J Biochem 2002; 132:831-9; PMID:12473183; http://dx.doi.org/10.1093/oxfordjournals. jbchem.a003294
-
(2002)
J Biochem
, vol.132
, pp. 831-839
-
-
Kikkawa, U.1
Matsuzaki, H.2
Yamamoto, T.3
-
48
-
-
0036523088
-
Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
-
PMID:11880503
-
Anantharam V, Kitazawa M, Wagner J, Kaul S, Kanthasamy AG. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. J Neurosci 2002; 22:1738-51; PMID:11880503
-
(2002)
J Neurosci
, vol.22
, pp. 1738-1751
-
-
Anantharam, V.1
Kitazawa, M.2
Wagner, J.3
Kaul, S.4
Kanthasamy, A.G.5
-
49
-
-
0038433325
-
Dieldrin induces apoptosis by promoting caspase- 3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: Relevance to oxidative stress and dopaminergic degeneration
-
PMID:12831855
-
Kitazawa M, Anantharam V, Kanthasamy AG. Dieldrin induces apoptosis by promoting caspase- 3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration. Neuroscience 2003; 119:945-64; PMID:12831855; http://dx.doi. org/10.1016/S0306-4522(03)00226-4
-
(2003)
Neuroscience
, vol.119
, pp. 945-964
-
-
Kitazawa, M.1
Anantharam, V.2
Kanthasamy, A.G.3
-
50
-
-
36749025313
-
Protein kinase Cdelta and apoptosis
-
PMID:17956263
-
Reyland ME. Protein kinase Cdelta and apoptosis. Biochem Soc Trans 2007; 35:1001-4; PMID:17956263; http://dx.doi.org/10.1042/ BST0351001
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1001-1004
-
-
Reyland, M.E.1
-
51
-
-
33747093723
-
Oxidative stress in the brain at early preclinical stages of mouse scrapie
-
PMID:16806186
-
Yun SW, Gerlach M, Riederer P, Klein MA. Oxidative stress in the brain at early preclinical stages of mouse scrapie. Exp Neurol 2006; 201:90- 8; PMID:16806186; http://dx.doi.org/10.1016/j. expneurol.2006.03.025
-
(2006)
Exp Neurol
, vol.201
, pp. 90-98
-
-
Yun, S.W.1
Gerlach, M.2
Riederer, P.3
Klein, M.A.4
-
52
-
-
0027365520
-
Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system
-
PMID:8263228
-
Merchenthaler I, Liposits Z, Reid JJ, Wetsel WC. Light and electron microscopic immunocytochemical localization of PKC delta immunoreactivity in the rat central nervous system. J Comp Neurol 1993; 336:378-99; PMID:8263228; http://dx.doi. org/10.1002/cne.903360306
-
(1993)
J Comp Neurol
, vol.336
, pp. 378-399
-
-
Merchenthaler, I.1
Liposits, Z.2
Reid, J.J.3
Wetsel, W.C.4
-
53
-
-
0034645382
-
Regional and cellular distribution of protein kinase C in rat cerebellar Purkinje cells
-
PMID:11054691
-
Barmack NH, Qian Z, Yoshimura J. Regional and cellular distribution of protein kinase C in rat cerebellar Purkinje cells. J Comp Neurol 2000; 427:235-54; PMID:11054691; http://dx.doi.org/10.1002/1096-9861(20001113)427: 2<235::AID-CNE6>3.0.CO;2-6
-
(2000)
J Comp Neurol
, vol.427
, pp. 235-254
-
-
Barmack, N.H.1
Qian, Z.2
Yoshimura, J.3
-
54
-
-
33750445915
-
Sporadic Creutzfeldt-Jakob disease with cerebellar ataxia at onset in the UK
-
PMID:16835290
-
Cooper SA, Murray KL, Heath CA, Will RG, Knight RS. Sporadic Creutzfeldt-Jakob disease with cerebellar ataxia at onset in the UK. J Neurol Neurosurg Psychiatry 2006; 77:1273-5; PMID:16835290; http://dx.doi.org/10.1136/ jnnp.2006.088930
-
(2006)
J Neurol Neurosurg Psychiatry
, vol.77
, pp. 1273-1275
-
-
Cooper, S.A.1
Murray, K.L.2
Heath, C.A.3
Will, R.G.4
Knight, R.S.5
-
55
-
-
16844370011
-
Human prion diseases: Molecular and clinical aspects
-
PMID:15824251
-
Glatzel M, Stoeck K, Seeger H, Lührs T, Aguzzi A. Human prion diseases: molecular and clinical aspects. Arch Neurol 2005; 62:545-52; PMID:15824251; http://dx.doi.org/10.1001/archneur.62.4.545
-
(2005)
Arch Neurol
, vol.62
, pp. 545-552
-
-
Glatzel, M.1
Stoeck, K.2
Seeger, H.3
Lührs, T.4
Aguzzi, A.5
-
56
-
-
85003230044
-
Measuring the strength of mice
-
PMID:23770643
-
Deacon RM. Measuring the strength of mice. J Vis Exp 2013; PMID:23770643
-
(2013)
J Vis Exp
-
-
Deacon, R.M.1
-
57
-
-
45049085458
-
Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation
-
PMID:18502140
-
Chou AH, Yeh TH, Ouyang P, Chen YL, Chen SY, Wang HL. Polyglutamine-expanded ataxin-3 causes cerebellar dysfunction of SCA3 transgenic mice by inducing transcriptional dysregulation. Neurobiol Dis 2008; 31:89-101; PMID:18502140; http:// dx.doi.org/10.1016/j.nbd.2008.03.011
-
(2008)
Neurobiol Dis
, vol.31
, pp. 89-101
-
-
Chou, A.H.1
Yeh, T.H.2
Ouyang, P.3
Chen, Y.L.4
Chen, S.Y.5
Wang, H.L.6
-
58
-
-
80055101576
-
A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia
-
PMID:20495529
-
Guyenet SJ, Furrer SA, Damian VM, Baughan TD, La Spada AR, Garden GA. A simple composite phenotype scoring system for evaluating mouse models of cerebellar ataxia. J Vis Exp 2010; PMID:20495529; http://dx.doi.org/10.3791/1787
-
(2010)
J Vis Exp
-
-
Guyenet, S.J.1
Furrer, S.A.2
Damian, V.M.3
Baughan, T.D.4
La Spada, A.R.5
Garden, G.A.6
-
59
-
-
84881224985
-
The peptidylprolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: Relevance to the pathogenesis of Parkinson disease
-
PMID:23754278
-
Ghosh A, Saminathan H, Kanthasamy A, Anantharam V, Jin H, Sondarva G, Harischandra DS, Qian Z, Rana A, Kanthasamy AG. The peptidylprolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. J Biol Chem 2013; 288:21955-71; PMID:23754278; http://dx.doi. org/10.1074/jbc.M112.444224
-
(2013)
J Biol Chem
, vol.288
, pp. 21955-21971
-
-
Ghosh, A.1
Saminathan, H.2
Kanthasamy, A.3
Anantharam, V.4
Jin, H.5
Sondarva, G.6
Harischandra, D.S.7
Qian, Z.8
Rana, A.9
Kanthasamy, A.G.10
-
60
-
-
33749522194
-
A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models
-
PMID:17045926
-
Kanthasamy AG, Anantharam V, Zhang D, Latchoumycandane C, Jin H, Kaul S, Kanthasamy A. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models. Free Radic Biol Med 2006; 41:1578-89; PMID:17045926; http://dx.doi.org/10.1016/j. freeradbiomed.2006.08.016
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1578-1589
-
-
Kanthasamy, A.G.1
Anantharam, V.2
Zhang, D.3
Latchoumycandane, C.4
Jin, H.5
Kaul, S.6
Kanthasamy, A.7
-
61
-
-
0037171731
-
Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta
-
PMID:11976687
-
Miyamoto A, Nakayama K, Imaki H, Hirose S, Jiang Y, Abe M, Tsukiyama T, Nagahama H, Ohno S, Hatakeyama S, et al. Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta. Nature 2002; 416:865-9; PMID:11976687; http://dx.doi.org/10.1038/416865a
-
(2002)
Nature
, vol.416
, pp. 865-869
-
-
Miyamoto, A.1
Nakayama, K.2
Imaki, H.3
Hirose, S.4
Jiang, Y.5
Abe, M.6
Tsukiyama, T.7
Nagahama, H.8
Ohno, S.9
Hatakeyama, S.10
-
62
-
-
33846538022
-
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice
-
PMID:17270731
-
Mallucci GR, White MD, Farmer M, Dickinson A, Khatun H, Powell AD, Brandner S, Jefferys JG, Collinge J. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron 2007; 53:325-35; PMID:17270731; http://dx.doi. org/10.1016/j. neuron.2007.01.005
-
(2007)
Neuron
, vol.53
, pp. 325-335
-
-
Mallucci, G.R.1
White, M.D.2
Farmer, M.3
Dickinson, A.4
Khatun, H.5
Powell, A.D.6
Brandner, S.7
Jefferys, J.G.8
Collinge, J.9
-
63
-
-
0034883360
-
Early behavioural changes in scrapie-affected mice and the influence of dapsone
-
PMID:11553290
-
Guenther K, Deacon RM, Perry VH, Rawlins JN. Early behavioural changes in scrapie-affected mice and the influence of dapsone. Eur J Neurosci 2001; 14:401-9; PMID:11553290; http://dx.doi. org/10.1046/j.0953-816x.2001.01645.x
-
(2001)
Eur J Neurosci
, vol.14
, pp. 401-409
-
-
Guenther, K.1
Deacon, R.M.2
Perry, V.H.3
Rawlins, J.N.4
|