Is There a Place for Dietary Fiber Supplements in Weight Management?

Current Obesity Reports

Volumn 1, Issue 2, 2012, Pages 59-67

  Lyon, Michael R ^a,b   Kacinik, Veronica ^a  

^a Canadian Centre for Functional Medicine   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Appetite regulation; Bile acid receptors; CCK; Dietary fiber; Free fatty acid receptors; GLP 1; Glycemic index; L cells; Obesity; Oxyntomodulin; PYY

Indexed keywords

APPETITE STIMULANT; CHOLECYSTOKININ; CHOLESTEROL; GHRELIN; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; INCRETIN; INSULIN; ISPAGULA; LAXATIVE; OXYNTOMODULIN; PEPTIDE YY; PREBIOTIC AGENT; PROBIOTIC AGENT; SHORT CHAIN FATTY ACID; URIC ACID;

BIFIDOBACTERIUM; BRAN; CALORIC INTAKE; DIET SUPPLEMENTATION; DIETARY FIBER; FERMENTATION; GLUCOSE BLOOD LEVEL; GLYCEMIC INDEX; GLYCEMIC LOAD; HIGH FIBER DIET; HUMAN; INTESTINE TRANSIT TIME; NEUROENDOCRINOLOGY; NONHUMAN; NUTRITIONAL DEFICIENCY; OBESITY; PALATABILITY; PRIORITY JOURNAL; REVIEW; SATIETY; STOMACH EMPTYING; VISCOSITY; WATER ABSORPTION; WEIGHT REDUCTION;

EID: 84896872260     PISSN: None     EISSN: 21624968     Source Type: Journal    
DOI: 10.1007/s13679-012-0016-9     Document Type: Review

References (85)

1. Wanders AJ, van den Borne JJ, de Graaf C, Hulshof T, Jonathan MC, Kristensen M, et al. Effects of dietary fibre on subjective appetite, energy intake and body weight: a systematic review of randomized controlled trials. Obes Rev. 2011; 12(9): 724-39. doi: 10. 1111/j. 1467-789X. 2011. 00895. x. Epub 2011 Jun 16.
2. Dietary, Functional and Total fiber, In Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein, and amino acids (macronutrients). US Department of Agriculture, National Agricultural Library and National Academy of Sciences, Institute of Medicine, Food and Nutrition Board. Washington, DC: National Academies Press; 2005. p. 339-421.
3. Institute of Medicine. Dietary Reference Intakes: proposed definitions of dietary fiber. Washington: National Academy Press; 2001.
4. The Codex Alimentaris Commision of the World Health Organization and the Food and Agriculture Organization of the United Nations. Report Of The 30th Session of the Codex Committee on Nutrition and Foods for Special Dietary Uses. Cape Town, South Africa. 3-7 November 2008.
5. Dietary intake of vitamins, minerals, and fiber of persons ages 2 months and over in the United States: Third National Health and Nutrition Examination Survey, Phase 1, 1988-1991. Advance Data from Vital and Health Statistics, No. 258. Hyattsville, MD: National Center for Health Statistics.
6. Lindberg S. Food and western disease; health and nutrition from an evolutionary perspective. Hoboken: Wiley; 2010.
7. Timm D, Slavin J. Dietary fiber and the relationship to chronic diseases. Am J Lifestyle Med. 2008; 2: 233-40.
8. Hur IY, Reicks M. Relationship between Whole-Grain Intake, Chronic Disease Risk Indicators, and Weight Status among Adolescents in the National Health and Nutrition Examination Survey. J Am Diet Assoc. 2011. [Epub ahead of print], 1999-2004.
9. Mälkki A. Physical properties of dietary fiber as keys to physiological functions. Cereal Foods World. 2001; 46: 196-9.
10. Edwards CA. The physiological effects of dietary fiber. In: Kritchevsky D, Bonfield C, editors. Dietary fiber in health and disease. St. Paul: Eagan Press; 1995. p. 58-71.
11. de Graaf C, Blom WA, Smeets PA, Stafleu A, Hendriks HF. Biomarkers of satiation and satiety. Am J Clin Nutr. 2004; 79: 946-61.
12. Hoad CL, Rayment P, Spiller RC, et al. In vivo imaging of intragastric gelation and its effect on satiety in humans. J Nutr. 2004; 134: 2293-300.
13. Marciani L, Gowland PA, Spiller RC, Manoj P, Moore RJ, Young P, et al. Gastric response to increased meal viscosity assessed by echo-planar magnetic resonance imaging in humans. J Nutr. 2000; 130: 122-7.
14. Overduin J, Frayo RS, Grill HJ, Kaplan JM, Cummings DE. Role of the duodenum and macronutrient type in ghrelin regulation. Endocrinology. 2005; 146: 845-50.
15. Dikeman C, Fahey G. Viscosity as related to dietary fiber: a review. Crit Rev Food Sci Nutr. 2006; 46: 649-63.
16. Koguchi T, Nakajima H, Koguchi H, et al. Suppressive effect of viscous dietary fiber on elevations of uric acid in serum and urine induced by dietary RNA in rats is associated with strength of viscosity. Int J Vitam Nutr Res. 2003; 73: 369-76.
17. Kristensen M, Jensen MG. Dietary fibres in the regulation of appetite and food intake. Importance of viscosity. Appetite. 2011; 56(1): 65-70. Epub 2010 Nov 27. This review summarizes the evidence supporting the notion that the viscosity of a dietary fiber is preeminent with regard to its effects upon appetite and quantity of food consumed.
18. Ito H, Satsukawa M, Arai E, et al. Soluble fiber viscosity affects both goblet cell number and small intestine mucin secretion in rats. J Nutr. 2009; 139: 1640-7.
19. Bourne M. Food texture and viscosity: concept and measurement. 2nd ed. San Diego: Academic; 2002.
20. Jenkins DJ, Wolever TM, Leeds AR, et al. Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity. BMJ. 1978; 1: 1392-4.
21. Chaudhri O, Small C, Bloom S. Gastrointestinal hormones regulating appetite. Phil Trans Biol Sci. 2006; 361: 1187-209.
22. Thomas S, Schauer P. Bariatric surgery and the gut hormone response. Nutr Clin Pract. 2010; 25(2): 175-82. This paper reviews the evidence that the principle mechanism underlying the response to gastric bypass surgery is related to an increase in the transit of nutrients to the distal bowel. This is thought to improve glucose metabolism and reduce appetite by stimulating secretion of GLP-1 and other appetite-suppressing gut peptides.
23. Flood JE, Rolls BJ. Soup preloads in a variety of forms reduce meal energy intake. Appetite. 2007; 49: 626-34.
24. Roe LS, Meengs JS, Rolls BJ. Salad and satiety. The effect of timing of salad consumption on meal energy intake. Appetite. 2012; 58: 242-8. Eating a larger salad with meals reduces caloric intake of the whole meal in most people.
25. Spill MK, Birch LL, Roe LS, Rolls BJ. Hiding vegetables to reduce energy density: an effective strategy to increase children's vegetable intake and reduce energy intake. Am J Clin Nutr. 2011; 94(3): 735-41. Epub 2011 Jul 20. We all know that eating more vegetables promotes a reduced caloric intake. This study demonstrates that high-fiber vegetables can be hidden in foods resulting in increased vegetable fiber intake.
26. Kacinik V, Lyon M, Purnama M, Reimer RA, Gahler R, Green TJ and Wood S. Effect of PGX, a novel functional fibre supplement, on subjective ratings of appetite in overweight and obese women consuming a 3-day structured, low-calorie diet. Nutr Diabetes. (2011); 1: e22; doi: 10. 1038/nutd. 2011. 18. In this double-blind placebo-controlled crossover trial, we showed that the addition of a highly viscous fiber supplement sprinkled on foods in easily consumed doses reduced hunger and promoted satiety in women consuming a structured 1000-kcal/day diet.
27. Rolls BJ. Plenary lecture 1: Dietary strategies for the prevention and treatment of obesity. Proc Nutr Soc. 2010; 69: 70-9. An excellent review of the use of reduced energy-density diets in weight management.
28. Ello-Martin JA, Roe LS, Ledikwe JH, et al. Dietary energy density in the treatment of obesity: a year-long trial comparing 2 weight-loss diets. Am J Clin Nutr. 2007; 85: 1465-77.
29. Rolls BJ. The relationship between dietary energy density and energy intake. Physiol Behav. 2009; 97: 609-15.
30. Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr. 1995; 125: 1401-12.
31. Roberfroid M. Prebiotics: concept, definition, criteria, methodologies, and products. In: Gibson GR, Roberfroid M, editors. Handbook of prebiotics. Boca Raton: CRC; 2008. p. 39-69.
32. Dewulf EM, Cani PD, Neyrink AM, et al. Inulin-type fructans with prebiotic properties counteract GPR43 overexpression and PPARgamma-related adipogenesis in the white adipose tissue of high-fat diet-fed mice. J Nutr Biochem. 2011; 22: 712-22.
33. Delzenne NM, Cani PD. Interaction between obesity and the gut microbiota: relevance in nutrition. Annu Rev Nutr. 2011; 31: 15-31.
34. Gruber C. Prevention of allergy by pro- and prebiotics. Exp Rev Clin Immunol. 2009; 5: 1-3.
35. Eiwegger T, Stahl B, Haidl P. Prebiotic oligosaccharides: in vitro evidence for gastrointestinal epithelial transfer and immunomodulatory properties. Pediatr Allergy Immunol. 2010; 21: 1179-88.
36. van der Aa LB, van Aalderen WM, Heymans HS. et al; Synbad Study Group. Synbiotics prevent asthma-like symptoms in infants with atopic dermatitis. Allergy. 2011; 66: 170-7.
37. Gruber C, van Stuijvenberg M, Mosca F, et al. MIPS 1 Working Group. Reduced occurrence of early atopic dermatitis because of immunoactive prebiotics among low-atopy-risk infants. J Allergy Clin Immunol. 2010; 126: 791-7.
38. Mallappa RH, Rokana N, Duary RK, Panwar H, Batish VK, Grover S. Management of metabolic syndrome through probiotic and prebiotic interventions. Indian J Endocrinol Metab. 2012; 16(1): 20-7.
39. Frazier TH, DiBaise JK, McClain CJ. Gut microbiota, intestinal permeability, obesity-induced inflammation, and liver injury. J Parenter Enteral Nutr. 2011; 35(5 Suppl): 14S-20. Epub 2011 Aug 1.
40. Maurer AD, Eller LK, Hallam MC, et al. Consumption of diets high in prebiotic fiber or protein during growth influences the response to a high fat and sucrose diet in adulthood in rats. Nutr Metab. 2010; 7: 77.
41. Veereman-Wauters G, Staelens S, van de Broek H, et al. Physiological and bifidogenic effects of prebiotic supplements in infant formulae. J Pediatr Gastroenterol Nutr. 2011; 52: 763-71.
42. Angelakis E, Armougom F, Million M, Raoult D. The relationship between gut microbiota and weight gain in humans. Future Microbiol. 2012; 7(1): 91-109.
43. Kaji I, Karaki S, Tanaka R, Kuwahara A. Density distribution of free fatty acid receptor 2 (FFA2)-expressing and GLP-1-producing enteroendocrine L cells in human and rat lower intestine, and increased cell numbers after ingestion of fructo-oligosaccharide. J Molecular Histol. 2011; 42: 27-38.
44. Strader AD, Woods SC. Gastrointestinal hormones and food intake. Gastroenterology. 2005; 128: 175-91.
45. Maljaars PW, Peters HP, Mela DJ, Masclee AA. Ileal brake: a sensible food target for appetite control. A review. Physiol Behav. 2008; 95(3): 271-81. Epub 2008 Jul 21.
46. Cummings DE. Endocrine mechanisms mediating remission of diabetes after gastric bypass surgery. Int J Obes. 2009; 33 Suppl 1: S33-40.
47. Katsuma S, Hirasawa A, Tsujimoto G. Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1. Biochem Biophys Res Commun. 2005; 329: 386-90.
48. Reimann F, Ward PS, Gribble FM. Signalling mechanisms underlying the release of glucagon-like peptide-1. Diabetes. 2006; 55 Suppl 2: S78-85.
49. Hirasawa A, Tsumaya K, Awaji T, et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nat Med. 2005; 11: 90-4.
50. Tolhurst G, Reimann F, Gribble FM. Nutritional regulation of glucagon-like peptide-1 secretion. J Physiol. 2009; 587: 27-32.
51. Patti ME, Houten SM, Bianco AC, et al. Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism. Obesity. 2009; 17: 1671-7.
52. Ichimura A, Hirasawa A, Hara T, Tsujimoto G. Free fatty acid receptors act as nutrient sensors to regulate energy homeostasis. Prostag Other Lipid Mediat. 2009; 89: 82-8.
53. Lin HC, Zhao XT, Chu AW, Lin YP, Wang L. Fiber-supplemented enteral formula slows intestinal transit by intensifying inhibitory feedback from the distal gut. Am J Clin Nutr. 1997; 65: 1840-4.
54. Wen J, Phillips SF, Sarr MG, Kost LJ, Holst JJ. PYY and GLP-1 contribute to feedback inhibition from the canine ileum and colon. Am J Physiol. 1995; 269: G945-52.
55. Roberts RE, Glicksman C, Alaghband-Zadeh J, et al. The relationship between postprandial bile acid concentration, GLP-1, PYY and ghrelin. Clin Endocrinol. 2011; 74: 67-72.
56. Knop FK. Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes? Am J Physiol Endocrinol Metab. 2011; 299: E10-3.
57. Sanchez D, Miguel M, Aleixandre A. Dietary fiber, gut peptides, and adipocytokines. J Med Food. 2011; [Epub ahead of print].
58. Jones PJ. Dietary agents that target gastrointestinal and hepatic handling of bile acids and cholesterol. J Clin Lipid. 2008; 2: S4-10.
59. Wolever TM. Relationship between dietary fiber content and composition in foods and the glycemic index. Am J Clin Nutr. 1990; 51(1): 72-5.
60. Kochan AM, Wolever TM, Chetty VT, Anand SS, Gerstein HC, Sharma AM. Glycemic index predicts individual glucose responses after self-selected breakfasts in free-living, abdominally obese adults. J Nutr. 2012; 142(1): 27-32. Epub 2011 Nov 16.
61. Bao J, Atkinson F, Petocz P, Willett WC, Brand-Miller JC. Prediction of postprandial glycemia and insulinemia in lean, young, healthy adults: glycemic load compared with carbohydrate content alone. Am J Clin Nutr. 2011; 93(5): 984-96. Epub 2011 Feb 16.
62. Fabricatore AN, Ebbeling CB, Wadden TA, Ludwig DS. Continuous glucose monitoring to assess the ecologic validity of dietary glycemic index and glycemic load. Am J Clin Nutr. 2011; 94(6): 1519-24. Epub 2011 Nov 9.
63. Krog-Mikkelsen I, Sloth B, Dimitrov D, Tetens I, Björck I, Flint A, et al. A low glycemic index diet does not affect postprandial energy metabolism but decreases postprandial insulinemia and increases fullness ratings in healthy women. J Nutr. 2011; 141(9): 1679-84. Epub 2011 Jul 20.
64. Esfahani A, Wong JM, Mirrahimi A, Villa CR, Kendall CW. The application of the glycemic index and glycemic load in weight loss: A review of the clinical evidence. IUBMB Life. 2011; 63(1): 7-13. doi: 10. 1002/iub. 418.
65. Larsen TM, Dalskov SM, van Baak M, Jebb SA, Papadaki A, Pfeiffer AF, et al. Diets with high or low protein content and glycemic index for weight-loss maintenance. N Engl J Med. 2010; 363(22): 2102-13. This discusses the Diogenes trial, a landmark study that demonstrated superiority of a low GI, moderately high protein diet in the maintenance of weight loss.
66. Gögebakan O, Kohl A, Osterhoff MA, van Baak MA, Jebb SA, Papadaki A, et al. Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: the diet, obesity, and genes (DiOGenes) study: a randomized, controlled trial. Circulation. 2011; 124(25): 2829-38. Epub 2011 Nov 21.
67. Krishnamurthy VM, Wei G, Baird BC, Murtaugh M, Chonchol MB, Raphael KL, et al. High dietary fiber intake is associated with decreased inflammation and all-cause mortality in patients with chronic kidney disease. Kidney Int. 2012; 81(3): 300-6. doi: 10. 1038/ki. 2011. 355. Epub 2011 Oct 19.
68. Chuang SC, Vermeulen R, Sharabiani MT, Sacerdote C, Fatemeh SH, Berrino F, et al. The intake of grain fibers modulates cytokine levels in blood. Biomarkers. 2011; 16(6): 504-10. doi: 10. 3109/1354750X. 2011. 599042. Epub 2011 Aug 3.
69. Sánchez D, Quiñones M, Moulay L, Muguerza B, Miguel M, Aleixandre A. Soluble fiber-enriched diets improve inflammation and oxidative stress biomarkers in Zucker fatty rats. Pharmacol Res. 2011; 64(1): 31-5. Epub 2011 Feb 22.
70. Lyon M, Wood S, Pelletier X, Donazzolo Y, Gahler R, Bellisle F. Effects of a 3-month supplementation with a novel soluble highly viscous polysaccharide on anthropometry and blood lipids in non-dieting overweight or obese adults. J Hum Nutr Diet. 2011; 24(4): 351-9.
71. Brand-Miller JC, Atkinson FS, Gahler RJ, Kacinik V, Lyon MR, Wood S. Effects of PGX, a novel functional fibre, on acute and delayed postprandial glycaemia. Eur J Clin Nutr. 2010; 64: 1488-93. We demonstrated the effect of consuming varying doses of a highly viscous fiber supplement on the GI.
72. Jenkins AL, Kacinik V, Lyon M, Wolever TM. Effect of adding the novel fiber, PGX, to commonly consumed foods on glycemic response, glycemic index and GRIP: a simple and effective strategy for reducing post prandial blood glucose levels-a randomized, controlled trial. Nutr J. 2010; 9: 58.
73. Jenkins AL, Kacinik V, Lyon M, Wolever TM. Reduction of postprandial glycemia by the novel viscous polysaccharide PGX, in a dose-dependent manner, independent of food form. J Am Coll Nutr. 2010; 29: 92-8. We showed that it is possible to substantially reduce the GI of commonly consumed foods with the addition of small doses of a highly viscous dietary fiber.
74. Vuksan V, Panahi S, Lyon M, et al. Viscosity of fiber preloads affects food intake in adolescents. Nutr Metab Cardiovasc Dis. 2009; 19: 498-503.
75. Brand-Miller JC, Atkinson FS, Gahler RJ, Kacinik V, Lyon MR, Wood S. Effects of added PGX®, a novel functional fibre, on the glycaemic index of starchy foods. Br J Nutr. 2011; 10: 1-4.
76. Reimer RA, Pelletier X, Carabin IG, et al. Differences in faecal short chain fatty acids in healthy subjects consuming placebo versus the functional fibre, PolyGlycopleX®. J Hum Nutr Diet. 2012; doi: 10. 1111/j. 1365-277X. 2012. 01230. x. [Epub ahead of print].
77. Pelletier X, Carabin IG, Lyon M, et al. Increased plasma PYY levels following supplementation with the functional fiber PolyGlycopleX in healthy adults. Eur J Clin Nutr. 2010; 64: 1186-91.
78. Grover GJ, Koetzner L, Wicks J, Gahler RJ, Lyon MR, Reimer RA, et al. Effects of the soluble fiber complex PolyGlycopleX on glucose homeostasis and body weight in young zucker diabetic rats. Front Pharmacol. 2011; 2: 47. Epub 2011 Sep 7.
79. Grover GJ, Koetzner L, Wicks J, Gahler RJ, Lyon MR, Reimer RA, et al. Effects of the soluble fiber complex PolyGlycopleX® (PGX®) on glycemic control, insulin secretion, and GLP-1 levels in Zucker diabetic rats. Life Sci. 2011; 88(9-10): 392-9. Epub 2010 Nov 30.
80. Position of the American Dietetic Association: Health implications of dietary fiber. J Am Diet Assoc. 2002; 102: 993-1000.
81. Tucker LA, Thomas KS. Increasing total fiber intake reduces risk of weight and fat gains in women. J Nutr. 2009; 139(3): 576-81. Epub 2009 Jan 21.
82. Koh-Banerjee P, Franz M, Sampson L, Liu S, Jacobs Jr DR, Spiegelman D, et al. Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men. Am J Clin Nutr. 2004; 80(5): 1237-45.
83. Pal S, Khossousi A, Binns C, et al. The effect of a fibre supplement compared to a healthy diet on body composition, lipids, glucose, insulin and other metabolic syndrome risk factors in overweight and obese individuals. Br J Nutr. 2011; 105: 90-100. Pal et al. demonstrate the usefulness of psyllium supplementation in short-term weight loss.
84. Howarth NC, Saltzman E, McCrory MA, et al. Fermentable and nonfermentable fiber supplements did not alter hunger, satiety or body weight in a pilot study of men and women consuming self-selected diets. J Nutr. 2003; 133: 3141-4.
85. Saquib N, Natarajan L, Rock CL, Flatt SW, Madlensky L, Kealey S, et al. The impact of a long-term reduction in dietary energy density on body weight within a randomized diet trial. Nutr Cancer. 2008; 60(1): 31-8.