TRPM2 channels mediate acetaminophen-induced liver damage

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 8, 2014, Pages 3176-3181

  Kheradpezhouh, Ehsan ^a   Ma, Linlin ^a   Morphett, Arthur ^b   Barritt, Greg J ^b   Rychkov, Grigori Y ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE DERIVATIVE; ALANINE AMINOTRANSFERASE; ANTHRANILIC ACID; ASPARTATE AMINOTRANSFERASE; CALCIUM ION; CHLORPROMAZINE; CLOTRIMAZOLE; PARACETAMOL; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL M2;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL ACTIVATION; CELL MEMBRANE CONDUCTANCE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG BLOOD LEVEL; DRUG EFFECT; IMMUNOFLUORESCENCE; LIVER CELL; LIVER HISTOLOGY; MEMBRANE CURRENT; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REACTION TIME; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TOXIC HEPATITIS; WHOLE CELL PATCH CLAMP;

ACETAMINOPHEN; ANALYSIS OF VARIANCE; ANIMALS; BLOTTING, WESTERN; CALCIUM; DRUG-INDUCED LIVER INJURY; FLUORESCENCE; FURA-2; HEPATOCYTES; HYDROGEN PEROXIDE; MICE; MICE, KNOCKOUT; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRPM CATION CHANNELS;

EID: 84896823785     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1322657111     Document Type: Article

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