메뉴 건너뛰기




Volumn 8, Issue 2, 2014, Pages 163-172

Paracrine functions of fibrocytes to promote lung fibrosis

Author keywords

bone marrow; chemokines; growth factors; mesenchymal cells; periostin

Indexed keywords

CELL PROTEIN; GROWTH FACTOR; LEUKOTRIENE; MATRICELLULAR PROTEIN; PROSTAGLANDIN; PROTEINASE; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 84896790889     PISSN: 17476348     EISSN: 17476356     Source Type: Journal    
DOI: 10.1586/17476348.2014.862154     Document Type: Review
Times cited : (36)

References (113)
  • 1
    • 0031000283 scopus 로고    scopus 로고
    • The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ
    • Chesney J, Bacher M, Bender A, Bucala R. The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc. Natl Acad. Sci. USA 94(12), 6307-6312 (1997).
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , Issue.12 , pp. 6307-6312
    • Chesney, J.1    Bacher, M.2    Bender, A.3    Bucala, R.4
  • 2
    • 0031883714 scopus 로고    scopus 로고
    • Regulated production of type i collagen and inflammatory cytokines by peripheral blood fibrocytes
    • Chesney J, Metz C, Stavitsky AB, Bacher M, Bucala R. Regulated production of type I collagen and inflammatory cytokines by peripheral blood fibrocytes. J. Immunol. 160(1), 419-425 (1998).
    • (1998) J. Immunol , vol.160 , Issue.1 , pp. 419-425
    • Chesney, J.1    Metz, C.2    Stavitsky, A.B.3    Bacher, M.4    Bucala, R.5
  • 3
    • 0028535872 scopus 로고
    • Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair
    • Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol. Med. 1(1), 71-81 (1994).
    • (1994) Mol. Med , vol.1 , Issue.1 , pp. 71-81
    • Bucala, R.1    Spiegel, L.A.2    Chesney, J.3    Hogan, M.4    Cerami, A.5
  • 4
    • 0347418197 scopus 로고    scopus 로고
    • Collagens, modifying enzymes and their mutations in humans, flies and worms
    • Myllyharju J, Kivirikko KI. Collagens, modifying enzymes and their mutations in humans, flies and worms. Trends Genet. 20(1), 33-43 (2004).
    • (2004) Trends Genet , vol.20 , Issue.1 , pp. 33-43
    • Myllyharju, J.1    Kivirikko, K.I.2
  • 5
    • 73449133450 scopus 로고    scopus 로고
    • The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis
    • Strieter RM, Keeley EC, Burdick MD, Mehrad B. The role of circulating mesenchymal progenitor cells, fibrocytes, in promoting pulmonary fibrosis. Trans. Am. Clin. Climatol. Assoc. 120, 49-59 (2009).
    • (2009) Trans. Am. Clin. Climatol. Assoc , vol.120 , pp. 49-59
    • Strieter, R.M.1    Keeley, E.C.2    Burdick, M.D.3    Mehrad, B.4
  • 6
    • 14644402494 scopus 로고    scopus 로고
    • CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury
    • Moore BB, Kolodsick JE, Thannickal VJ, et al. CCR2-mediated recruitment of fibrocytes to the alveolar space after fibrotic injury. Am. J. Pathol. 166(3), 675-684 (2005).
    • (2005) Am. J. Pathol , vol.166 , Issue.3 , pp. 675-684
    • Moore, B.B.1    Kolodsick, J.E.2    Thannickal, V.J.3
  • 8
    • 4043055316 scopus 로고    scopus 로고
    • Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
    • Phillips RJ, Burdick MD, Hong K, et al. Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J. Clin. Invest. 114(3), 438-446 (2004).
    • (2004) J. Clin. Invest , vol.114 , Issue.3 , pp. 438-446
    • Phillips, R.J.1    Burdick, M.D.2    Hong, K.3
  • 9
    • 80051600437 scopus 로고    scopus 로고
    • Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: Reversal by caveolin-1 scaffolding domain peptide
    • Tourkina E, Bonner M, Oates J, et al. Altered monocyte and fibrocyte phenotype and function in scleroderma interstitial lung disease: reversal by caveolin-1 scaffolding domain peptide. Fibrogenesis Tissue Repair 4(1), 15 (2011).
    • (2011) Fibrogenesis Tissue Repair , vol.4 , Issue.1 , pp. 15
    • Tourkina, E.1    Bonner, M.2    Oates, J.3
  • 10
    • 84876706037 scopus 로고    scopus 로고
    • A review of current and novel therapies for idiopathic pulmonary fibrosis
    • Rafii R, Juarez MM, Albertson TE, Chan AL. A review of current and novel therapies for idiopathic pulmonary fibrosis. J. Thorac Dis. 5(1), 48-73 (2013).
    • (2013) J. Thorac Dis , vol.5 , Issue.1 , pp. 48-73
    • Rafii, R.1    Juarez, M.M.2    Albertson, T.E.3    Chan, A.L.4
  • 11
    • 0038544594 scopus 로고    scopus 로고
    • Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
    • Schmidt M, Sun G, Stacey M, Mori L, Mattoli S. Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J. Immunol. 170, 380-389 (2003).
    • (2003) J. Immunol , vol.170 , pp. 380-389
    • Schmidt, M.1    Sun, G.2    Stacey, M.3    Mori, L.4    Mattoli, S.5
  • 12
    • 59449083238 scopus 로고    scopus 로고
    • Fibrocyte localization to the airway smooth muscle is a feature of asthma
    • Saunders R, Siddiqui S, Kaur D, et al. Fibrocyte localization to the airway smooth muscle is a feature of asthma. J. Allergy Clin. Immunol. 123(2), 376-384 (2009).
    • (2009) J. Allergy Clin. Immunol , vol.123 , Issue.2 , pp. 376-384
    • Saunders, R.1    Siddiqui, S.2    Kaur, D.3
  • 13
    • 51849104192 scopus 로고    scopus 로고
    • Increased circulating fibrocytes in asthma with chronic airflow obstruction
    • Wang CH, Huang CD, Lin HC, et al. Increased circulating fibrocytes in asthma with chronic airflow obstruction. Am. J. Respir. Crit. Care Med. 178(6), 583-591 (2008).
    • (2008) Am. J. Respir. Crit. Care Med , vol.178 , Issue.6 , pp. 583-591
    • Wang, C.H.1    Huang, C.D.2    Lin, H.C.3
  • 14
    • 84857215266 scopus 로고    scopus 로고
    • Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients
    • Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S. Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients. Mucosal. Immunol. 5(2), 140-149 (2012).
    • (2012) Mucosal. Immunol , vol.5 , Issue.2 , pp. 140-149
    • Bellini, A.1    Marini, M.A.2    Bianchetti, L.3    Barczyk, M.4    Schmidt, M.5    Mattoli, S.6
  • 15
    • 77954602335 scopus 로고    scopus 로고
    • Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
    • Mathai SK, Gulati M, Peng X, et al. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype. Lab. Invest. 90(6), 812-823 (2010).
    • (2010) Lab. Invest , vol.90 , Issue.6 , pp. 812-823
    • Mathai, S.K.1    Gulati, M.2    Peng, X.3
  • 16
    • 79961100313 scopus 로고    scopus 로고
    • Role of semaphorin 7a signaling in transforming growth factor beta1-induced lung fibrosis and scleroderma-related interstitial lung disease
    • Gan Y, Reilkoff R, Peng X, et al. Role of semaphorin 7a signaling in transforming growth factor beta1-induced lung fibrosis and scleroderma-related interstitial lung disease. Arthritis Rheum. 63(8), 2484-2494 (2011).
    • (2011) Arthritis Rheum , vol.63 , Issue.8 , pp. 2484-2494
    • Gan, Y.1    Reilkoff, R.2    Peng, X.3
  • 17
    • 77953694439 scopus 로고    scopus 로고
    • Caveolin-1 regulates leucocyte behaviour in fibrotic lung disease
    • Tourkina E, Richard M, Oates J, et al. Caveolin-1 regulates leucocyte behaviour in fibrotic lung disease. Ann. Rheum. Dis. 69(6), 1220-1226 (2010).
    • (2010) Ann. Rheum. Dis , vol.69 , Issue.6 , pp. 1220-1226
    • Tourkina, E.1    Richard, M.2    Oates, J.3
  • 19
    • 48949117344 scopus 로고    scopus 로고
    • Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
    • Andersson-Sjoland A, de Alba CG, Nihlberg K, et al. Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis. Int. J. Biochem. Cell Biol. 40(10), 2129-2140 (2008).
    • (2008) Int. J. Biochem. Cell Biol , vol.40 , Issue.10 , pp. 2129-2140
    • Andersson-Sjoland, A.1    De Alba, C.G.2    Nihlberg, K.3
  • 20
    • 65249098301 scopus 로고    scopus 로고
    • Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis
    • Moeller A, Gilpin SE, Ask K, et al. Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 179(7), 588-594 (2009).
    • (2009) Am. J. Respir. Crit. Care Med , vol.179 , Issue.7 , pp. 588-594
    • Moeller, A.1    Gilpin, S.E.2    Ask, K.3
  • 21
    • 84859900208 scopus 로고    scopus 로고
    • Correlation between circulating fibrocytes, and activity and progression of interstitial lung diseases
    • Fujiwara A, Kobayashi H, Masuya M, et al. Correlation between circulating fibrocytes, and activity and progression of interstitial lung diseases. Respirology 17(4), 693-698 (2012).
    • (2012) Respirology , vol.17 , Issue.4 , pp. 693-698
    • Fujiwara, A.1    Kobayashi, H.2    Masuya, M.3
  • 22
    • 84871320910 scopus 로고    scopus 로고
    • Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
    • Naik PK, Bozyk PD, Bentley JK, et al. Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis. Am. J. Physiol. Lung Cell. Mol. Physiol. 303(12), L1046-L1056. (2012).
    • (2012) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.303 , Issue.12
    • Naik, P.K.1    Bozyk, P.D.2    Bentley, J.K.3
  • 23
    • 84871902824 scopus 로고    scopus 로고
    • Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment
    • Garibaldi BT, D'Alessio FR, Mock JR, et al. Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment. Am. J. Respir. Cell Mol. Biol. 48(1), 35-43 (2013).
    • (2013) Am. J. Respir. Cell Mol. Biol , vol.48 , Issue.1 , pp. 35-43
    • Garibaldi, B.T.1    D'Alessio, F.R.2    Mock, J.R.3
  • 24
    • 84873999799 scopus 로고    scopus 로고
    • Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model
    • Harris DA, Zhao Y, Lapar DJ, et al. Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model. J. Thorac Cardiovasc. Surg. 145(3), 854-861 (2012).
    • (2012) J. Thorac Cardiovasc. Surg , vol.145 , Issue.3 , pp. 854-861
    • Harris, D.A.1    Zhao, Y.2    Lapar, D.J.3
  • 25
    • 84863389833 scopus 로고    scopus 로고
    • The role of fibrocytes in sickle cell lung disease
    • Field JJ, Burdick MD, DeBaun MR, et al. The role of fibrocytes in sickle cell lung disease. PLoS ONE 7(3), e33702 (2012).
    • (2012) PLoS ONE , vol.7 , Issue.3
    • Field, J.J.1    Burdick, M.D.2    Debaun, M.R.3
  • 26
    • 79960960615 scopus 로고    scopus 로고
    • Circulating fibrocytes correlate with bronchiolitis obliterans syndrome development after lung transplantation: A novel clinical biomarker
    • LaPar DJ, Burdick MD, Emaminia A, et al. Circulating fibrocytes correlate with bronchiolitis obliterans syndrome development after lung transplantation: a novel clinical biomarker. Ann. Thorac Surg. 92(2), 470-477 (2011).
    • (2011) Ann. Thorac Surg , vol.92 , Issue.2 , pp. 470-477
    • Lapar, D.J.1    Burdick, M.D.2    Emaminia, A.3
  • 27
    • 70349441112 scopus 로고    scopus 로고
    • Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
    • Tanjore H, Xu XC, Polosukhin VV, et al. Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis. Am. J. Respir. Crit. Care Med. 180(7), 657-665 (2009).
    • (2009) Am. J. Respir. Crit. Care Med , vol.180 , Issue.7 , pp. 657-665
    • Tanjore, H.1    Xu, X.C.2    Polosukhin, V.V.3
  • 29
    • 1242306647 scopus 로고    scopus 로고
    • The role of transforming growth factor beta in lung development and disease
    • Bartram U, Speer CP. The role of transforming growth factor beta in lung development and disease. Chest 125(2), 754-765 (2004).
    • (2004) Chest , vol.125 , Issue.2 , pp. 754-765
    • Bartram, U.1    Speer, C.P.2
  • 30
    • 0038544594 scopus 로고    scopus 로고
    • Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma
    • Schmidt M, Sun G, Stacey MA, Mori L, Mattoli S. Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma. J. Immunol. 171(1), 380-389 (2003).
    • (2003) J. Immunol , vol.171 , Issue.1 , pp. 380-389
    • Schmidt, M.1    Sun, G.2    Stacey, M.A.3    Mori, L.4    Mattoli, S.5
  • 31
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425(6958), 577-584 (2003).
    • (2003) Nature , vol.425 , Issue.6958 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 32
    • 37849008770 scopus 로고    scopus 로고
    • Inhibition of integrin alpha (v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis
    • Puthawala K, Hadjiangelis N, Jacoby SC, et al. Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis. Am. J. Respir. Crit. Care Med. 177(1), 82-90 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.177 , Issue.1 , pp. 82-90
    • Puthawala, K.1    Hadjiangelis, N.2    Jacoby, S.C.3
  • 34
    • 49049110677 scopus 로고    scopus 로고
    • Integrins and the activation of latent transforming growth factor beta1 - An intimate relationship
    • Wipff PJ, Hinz B. Integrins and the activation of latent transforming growth factor beta1 - an intimate relationship. Eur. J. Cell Biol. 87(8-9), 601-615 (2008).
    • (2008) Eur. J. Cell Biol , vol.87 , Issue.8-9 , pp. 601-615
    • Wipff, P.J.1    Hinz, B.2
  • 35
    • 79551525686 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors in the treatment of systemic sclerosis: From animal models to clinical trials
    • Iwamoto N, Distler JH, Distler O. Tyrosine kinase inhibitors in the treatment of systemic sclerosis: from animal models to clinical trials. Curr. Rheumatol. Rep. 13(1), 21-27 (2011).
    • (2011) Curr. Rheumatol. Rep , vol.13 , Issue.1 , pp. 21-27
    • Iwamoto, N.1    Distler, J.H.2    Distler, O.3
  • 36
    • 79251639838 scopus 로고    scopus 로고
    • Therapeutic effect of a peptide inhibitor of TGF-beta on pulmonary fibrosis
    • Arribillaga L, Dotor J, Basagoiti M, et al. Therapeutic effect of a peptide inhibitor of TGF-beta on pulmonary fibrosis. Cytokine 53(3), 327-333 (2011).
    • (2011) Cytokine , vol.53 , Issue.3 , pp. 327-333
    • Arribillaga, L.1    Dotor, J.2    Basagoiti, M.3
  • 37
    • 38049002642 scopus 로고    scopus 로고
    • Partial inhibition of integrin alpha (v)beta6 prevents pulmonary fibrosis without exacerbating inflammation
    • Horan GS, Wood S, Ona V, et al. Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation. Am. J. Respir. Crit. Care Med. 177(1), 56-65 (2008).
    • (2008) Am. J. Respir. Crit. Care Med. , vol.177 , Issue.1 , pp. 56-65
    • Horan, G.S.1    Wood, S.2    Ona, V.3
  • 39
    • 70449372660 scopus 로고    scopus 로고
    • Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts
    • Pilling D, Fan T, Huang D, Kaul B, Gomer RH. Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts. PLoS ONE 4(10), e7475 (2009).
    • (2009) PLoS ONE , vol.4 , Issue.10
    • Pilling, D.1    Fan, T.2    Huang, D.3    Kaul, B.4    Gomer, R.H.5
  • 40
    • 84860376241 scopus 로고    scopus 로고
    • Fibroproliferative disorders and their mechanobiology
    • Huang C, Ogawa R. Fibroproliferative disorders and their mechanobiology. Connect Tissue Res. 53(3), 187-196 (2012).
    • (2012) Connect Tissue Res , vol.53 , Issue.3 , pp. 187-196
    • Huang, C.1    Ogawa, R.2
  • 41
    • 33947109970 scopus 로고    scopus 로고
    • Mammalian collagen receptors
    • Leitinger B, Hohenester E. Mammalian collagen receptors. Matrix Biol. 26(3), 146-155 (2007).
    • (2007) Matrix Biol , vol.26 , Issue.3 , pp. 146-155
    • Leitinger, B.1    Hohenester, E.2
  • 42
    • 81255124245 scopus 로고    scopus 로고
    • Loss of discoidin domain receptor 2 promotes hepatic fibrosis after chronic carbon tetrachloride through altered paracrine interactions between hepatic stellate cells and liver-associated macrophages
    • Olaso E, Arteta B, Benedicto A, Crende O, Friedman SL. Loss of discoidin domain receptor 2 promotes hepatic fibrosis after chronic carbon tetrachloride through altered paracrine interactions between hepatic stellate cells and liver-associated macrophages. Am. J. Pathol. 179(6), 2894-2904 (2011).
    • (2011) Am. J. Pathol , vol.179 , Issue.6 , pp. 2894-2904
    • Olaso, E.1    Arteta, B.2    Benedicto, A.3    Crende, O.4    Friedman, S.L.5
  • 43
    • 70450222098 scopus 로고    scopus 로고
    • Matrix crosslinking forces tumor progression by enhancing integrin signaling
    • Levental KR, Yu H, Kass L, et al. Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139(5), 891-906 (2009).
    • (2009) Cell , vol.139 , Issue.5 , pp. 891-906
    • Levental, K.R.1    Yu, H.2    Kass, L.3
  • 44
    • 37249044357 scopus 로고    scopus 로고
    • Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix
    • Wipff PJ, Rifkin DB, Meister JJ, Hinz B. Myofibroblast contraction activates latent TGF-beta1 from the extracellular matrix. J. Cell Biol. 179(6), 1311-1323 (2007).
    • (2007) J. Cell Biol , vol.179 , Issue.6 , pp. 1311-1323
    • Wipff, P.J.1    Rifkin, D.B.2    Meister, J.J.3    Hinz, B.4
  • 45
    • 0031053724 scopus 로고    scopus 로고
    • Inverse correlation between CD34 expression and proline-4-hydroxylase immunoreactivity on spindle cells noted in hypertrophic scars and keloids
    • Aiba S, Tagami H. Inverse correlation between CD34 expression and proline-4-hydroxylase immunoreactivity on spindle cells noted in hypertrophic scars and keloids. J. Cutan Pathol. 24(2), 65-69 (1997).
    • (1997) J. Cutan Pathol , vol.24 , Issue.2 , pp. 65-69
    • Aiba, S.1    Tagami, H.2
  • 46
    • 27744574700 scopus 로고    scopus 로고
    • Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1
    • Fontana L, Chen Y, Prijatelj P, et al. Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1. FASEB J. 19(13), 1798-1808 (2005).
    • (2005) FASEB J , vol.19 , Issue.13 , pp. 1798-1808
    • Fontana, L.1    Chen, Y.2    Prijatelj, P.3
  • 47
    • 40949159343 scopus 로고    scopus 로고
    • An essential role for fibronectin extra type III domain A in pulmonary fibrosis
    • Muro AF, Moretti FA, Moore BB, et al. An essential role for fibronectin extra type III domain A in pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 177(6), 638-645 (2008).
    • (2008) Am. J. Respir. Crit. Care Med , vol.177 , Issue.6 , pp. 638-645
    • Muro, A.F.1    Moretti, F.A.2    Moore, B.B.3
  • 48
    • 18344396051 scopus 로고    scopus 로고
    • Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans
    • Zuo F, Kaminski N, Eugui E, et al. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc. Natl Acad. Sci. USA 99(9), 6292-6297 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , Issue.9 , pp. 6292-6297
    • Zuo, F.1    Kaminski, N.2    Eugui, E.3
  • 49
    • 65649096201 scopus 로고    scopus 로고
    • Matrix metalloproteinases in respiratory diseases: From pathogenesis to potential clinical implications
    • Oikonomidi S, Kostikas K, Tsilioni I, Tanou K, Gourgoulianis KI, Kiropoulos TS. Matrix metalloproteinases in respiratory diseases: from pathogenesis to potential clinical implications. Curr. Med. Chem. 16(10), 1214-1228 (2009).
    • (2009) Curr. Med. Chem , vol.16 , Issue.10 , pp. 1214-1228
    • Oikonomidi, S.1    Kostikas, K.2    Tsilioni, I.3    Tanou, K.4    Gourgoulianis, K.I.5    Kiropoulos, T.S.6
  • 50
    • 0031888875 scopus 로고    scopus 로고
    • Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis
    • Swiderski RE, Dencoff JE, Floerchinger CS, Shapiro SD, Hunninghake GW. Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis. Am. J. Pathol. 152(3), 821-828 (1998).
    • (1998) Am. J. Pathol , vol.152 , Issue.3 , pp. 821-828
    • Swiderski, R.E.1    Dencoff, J.E.2    Floerchinger, C.S.3    Shapiro, S.D.4    Hunninghake, G.W.5
  • 51
    • 0034815949 scopus 로고    scopus 로고
    • Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo
    • Hartlapp I, Abe R, Saeed RW, et al. Fibrocytes induce an angiogenic phenotype in cultured endothelial cells and promote angiogenesis in vivo. FASEB J. 15(12), 2215-2224 (2001).
    • (2001) FASEB J , vol.15 , Issue.12 , pp. 2215-2224
    • Hartlapp, I.1    Abe, R.2    Saeed, R.W.3
  • 52
    • 78349303445 scopus 로고    scopus 로고
    • Expression of matrix metalloproteases by fibrocytes: Possible role in migration and homing
    • Garcia-de-Alba C, Becerril C, Ruiz V, et al. Expression of matrix metalloproteases by fibrocytes: possible role in migration and homing. Am. J. Respir. Crit. Care Med. 182(9), 1144-1152 (2010).
    • (2010) Am. J. Respir. Crit. Care Med , vol.182 , Issue.9 , pp. 1144-1152
    • Garcia-De-Alba, C.1    Becerril, C.2    Ruiz, V.3
  • 53
    • 84868112181 scopus 로고    scopus 로고
    • Circulating fibrocytes contribute to the pathogenesis of collagen antibody-induced arthritis
    • Galligan CL, Fish EN. Circulating fibrocytes contribute to the pathogenesis of collagen antibody-induced arthritis. Arthritis Rheum. 64(11), 3583-3593 (2012).
    • (2012) Arthritis Rheum , vol.64 , Issue.11 , pp. 3583-3593
    • Galligan, C.L.1    Fish, E.N.2
  • 55
    • 46749127819 scopus 로고    scopus 로고
    • C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9
    • van Deventer HW, Wu QP, Bergstralh DT, et al. C-C chemokine receptor 5 on pulmonary fibrocytes facilitates migration and promotes metastasis via matrix metalloproteinase 9. Am. J. Pathol. 173(1), 253-264 (2008).
    • (2008) Am. J. Pathol , vol.173 , Issue.1 , pp. 253-264
    • Van Deventer, H.W.1    Wu, Q.P.2    Bergstralh, D.T.3
  • 56
    • 0034705208 scopus 로고    scopus 로고
    • Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice
    • Wert SE, Yoshida M, LeVine AM, et al. Increased metalloproteinase activity, oxidant production, and emphysema in surfactant protein D gene-inactivated mice. Proc. Natl Acad. Sci. USA 97(11), 5972-5977 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , Issue.11 , pp. 5972-5977
    • Wert, S.E.1    Yoshida, M.2    Levine, A.M.3
  • 57
    • 34748922290 scopus 로고    scopus 로고
    • Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin
    • Cabrera S, Gaxiola M, Arreola JL, et al. Overexpression of MMP9 in macrophages attenuates pulmonary fibrosis induced by bleomycin. Int. J. Biochem. Cell Biol. 39(12), 2324-2338 (2007).
    • (2007) Int. J. Biochem. Cell Biol , vol.39 , Issue.12 , pp. 2324-2338
    • Cabrera, S.1    Gaxiola, M.2    Arreola, J.L.3
  • 58
    • 0036775425 scopus 로고    scopus 로고
    • Matricellular proteins: Extracellular modulators of cell function
    • Bornstein P, Sage EH. Matricellular proteins: extracellular modulators of cell function. Curr. Opin. Cell Biol. 14(5), 608-616 (2002).
    • (2002) Curr. Opin. Cell Biol , vol.14 , Issue.5 , pp. 608-616
    • Bornstein, P.1    Sage, E.H.2
  • 59
    • 0347915577 scopus 로고    scopus 로고
    • CCN proteins: Multifunctional signalling regulators
    • Perbal B. CCN proteins: multifunctional signalling regulators. Lancet 363(9402), 62-64 (2004).
    • (2004) Lancet , vol.363 , Issue.9402 , pp. 62-64
    • Perbal, B.1
  • 60
    • 0442291674 scopus 로고    scopus 로고
    • The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology
    • Leask A, Abraham DJ. The role of connective tissue growth factor, a multifunctional matricellular protein, in fibroblast biology. Biochem. Cell. Biol. 81(6), 355-363 (2003).
    • (2003) Biochem. Cell. Biol , vol.81 , Issue.6 , pp. 355-363
    • Leask, A.1    Abraham, D.J.2
  • 61
    • 0036051343 scopus 로고    scopus 로고
    • Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta
    • Abreu JG, Ketpura NI, Reversade B, De Robertis EM. Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta. Nat. Cell Biol. 4(8), 599-604 (2002).
    • (2002) Nat. Cell Biol , vol.4 , Issue.8 , pp. 599-604
    • Abreu, J.G.1    Ketpura, N.I.2    Reversade, B.3    De Robertis, E.M.4
  • 62
    • 77951743012 scopus 로고    scopus 로고
    • Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis
    • Sonnylal S, Shi-Wen X, Leoni P, et al. Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis. Arthritis Rheum. 62(5), 1523-1532 (2010).
    • (2010) Arthritis Rheum , vol.62 , Issue.5 , pp. 1523-1532
    • Sonnylal, S.1    Shi-Wen, X.2    Leoni, P.3
  • 63
    • 77249143863 scopus 로고    scopus 로고
    • Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: Lessons from transgenic animals
    • Brigstock DR. Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals. J. Cell Commun. Signal. 4(1), 1-4 (2010).
    • (2010) J. Cell Commun. Signal , vol.4 , Issue.1 , pp. 1-4
    • Brigstock, D.R.1
  • 64
    • 0141596121 scopus 로고    scopus 로고
    • Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis
    • Bonniaud P, Margetts PJ, Kolb M, et al. Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. Am. J. Respir. Crit. Care Med. 168(7), 770-778 (2003).
    • (2003) Am. J. Respir. Crit. Care Med , vol.168 , Issue.7 , pp. 770-778
    • Bonniaud, P.1    Margetts, P.J.2    Kolb, M.3
  • 65
    • 84875779325 scopus 로고    scopus 로고
    • CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis
    • Lipson KE, Wong C, Teng Y, Spong S. CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis. Fibrogenesis Tissue Repair. 5 Suppl 1, S24 (2012).
    • (2012) Fibrogenesis Tissue Repair , vol.5 , Issue.1
    • Lipson, K.E.1    Wong, C.2    Teng, Y.3    Spong, S.4
  • 66
    • 84896788473 scopus 로고    scopus 로고
    • The et receptor mediates fibrocyte differentiation in chronic obstructive asthma: The involvement of CTGF
    • Weng CM, Chen BC, Wang CH, et al. The ET receptor mediates fibrocyte differentiation in chronic obstructive asthma: the involvement of CTGF. Am. J. Respir. Crit. Care Med. (2013).
    • (2013) Am. J. Respir. Crit. Care Med.
    • Weng, C.M.1    Chen, B.C.2    Wang, C.H.3
  • 67
    • 0032973197 scopus 로고    scopus 로고
    • Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta
    • Horiuchi K, Amizuka N, Takeshita S, et al. Identification and characterization of a novel protein, periostin, with restricted expression to periosteum and periodontal ligament and increased expression by transforming growth factor beta. J. Bone Miner. Res. 14(7), 1239-1249 (1999).
    • (1999) J. Bone Miner. Res , vol.14 , Issue.7 , pp. 1239-1249
    • Horiuchi, K.1    Amizuka, N.2    Takeshita, S.3
  • 68
    • 79955674250 scopus 로고    scopus 로고
    • Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias
    • Okamoto M, Hoshino T, Kitasato Y, et al. Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias. Eur. Respir. J. 37(5), 1119-1127 (2011).
    • (2011) Eur. Respir. J , vol.37 , Issue.5 , pp. 1119-1127
    • Okamoto, M.1    Hoshino, T.2    Kitasato, Y.3
  • 69
    • 33748796635 scopus 로고    scopus 로고
    • Mechanical tension and integrin alphaa beta 1 regulate fibroblast functions
    • Eckes B, Zweers MC, Zhang ZG, et al. Mechanical tension and integrin alphaa beta 1 regulate fibroblast functions. J. Investig. Dermatol. Symp. Proc. 11(1), 66-72 (2006).
    • (2006) J. Investig. Dermatol. Symp. Proc , vol.11 , Issue.1 , pp. 66-72
    • Eckes, B.1    Zweers, M.C.2    Zhang, Z.G.3
  • 70
    • 84868280901 scopus 로고    scopus 로고
    • The fibrotic matrix in control: Does the extracellular matrix drive progression of idiopathic pulmonary fibrosis?
    • Tschumperlin DJ, Jones JC, Senior RM. The fibrotic matrix in control: does the extracellular matrix drive progression of idiopathic pulmonary fibrosis? Am. J. Respir. Crit. Care Med. 186(9), 814-816 (2012).
    • (2012) Am. J. Respir. Crit. Care Med , vol.186 , Issue.9 , pp. 814-816
    • Tschumperlin, D.J.1    Jones, J.C.2    Senior, R.M.3
  • 71
    • 77956289251 scopus 로고    scopus 로고
    • Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma
    • Sidhu SS, Yuan S, Innes AL, et al. Roles of epithelial cell-derived periostin in TGF-beta activation, collagen production, and collagen gel elasticity in asthma. Proc. Natl Acad. Sci. USA 107(32), 14170-14175 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , Issue.32 , pp. 14170-14175
    • Sidhu, S.S.1    Yuan, S.2    Innes, A.L.3
  • 72
    • 0026541565 scopus 로고
    • Neutrophil chemotactic factors in the respiratory tract of patients with chronic airway diseases or idiopathic pulmonary fibrosis
    • Ozaki T, Hayashi H, Tani K, Ogushi F, Yasuoka S, Ogura T. Neutrophil chemotactic factors in the respiratory tract of patients with chronic airway diseases or idiopathic pulmonary fibrosis. Am. Rev. Respir. Dis. 145(1), 85-91 (1992).
    • (1992) Am. Rev. Respir. Dis , vol.145 , Issue.1 , pp. 85-91
    • Ozaki, T.1    Hayashi, H.2    Tani, K.3    Ogushi, F.4    Yasuoka, S.5    Ogura, T.6
  • 73
    • 0024474984 scopus 로고
    • Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory diseases
    • Wardlaw AJ, Hay H, Cromwell O, Collins JV, Kay AB. Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory diseases. J. Allergy Clin. Immunol. 84(1), 19-26 (1989).
    • (1989) J. Allergy Clin. Immunol , vol.84 , Issue.1 , pp. 19-26
    • Wardlaw, A.J.1    Hay, H.2    Cromwell, O.3    Collins, J.V.4    Kay, A.B.5
  • 74
    • 0030005712 scopus 로고    scopus 로고
    • Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis
    • Wilborn J, Bailie M, Coffey M, Burdick M, Strieter R, Peters-Golden M. Constitutive activation of 5-lipoxygenase in the lungs of patients with idiopathic pulmonary fibrosis. J. Clin. Invest. 97(8), 1827-1836 (1996).
    • (1996) J. Clin. Invest , vol.97 , Issue.8 , pp. 1827-1836
    • Wilborn, J.1    Bailie, M.2    Coffey, M.3    Burdick, M.4    Strieter, R.5    Peters-Golden, M.6
  • 75
    • 0028924146 scopus 로고
    • Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2
    • Wilborn J, Crofford LJ, Burdick MD, Kunkel SL, Strieter RM, Peters-Golden M. Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2. J. Clin. Invest. 95(4), 1861-1868 (1995).
    • (1995) J. Clin. Invest , vol.95 , Issue.4 , pp. 1861-1868
    • Wilborn, J.1    Crofford, L.J.2    Burdick, M.D.3    Kunkel, S.L.4    Strieter, R.M.5    Peters-Golden, M.6
  • 76
    • 38849161533 scopus 로고    scopus 로고
    • Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function
    • Vannella KM, McMillan TR, Charbeneau RP, et al. Cysteinyl leukotrienes are autocrine and paracrine regulators of fibrocyte function. J. Immunol. 179(11), 7883-7890 (2007).
    • (2007) J. Immunol , vol.179 , Issue.11 , pp. 7883-7890
    • Vannella, K.M.1    McMillan, T.R.2    Charbeneau, R.P.3
  • 77
    • 0023158760 scopus 로고
    • Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: Effect of indomethacin
    • Baud L, Perez J, Denis M, Ardaillou R. Modulation of fibroblast proliferation by sulfidopeptide leukotrienes: effect of indomethacin. J. Immunol. 138(4), 1190-1195 (1987).
    • (1987) J. Immunol , vol.138 , Issue.4 , pp. 1190-1195
    • Baud, L.1    Perez, J.2    Denis, M.3    Ardaillou, R.4
  • 78
    • 0023820012 scopus 로고
    • Binding of leukotriene C4 to rat lung fibroblasts and stimulation of collagen synthesis in vitro
    • Phan SH, McGarry BM, Loeffler KM, Kunkel SL. Binding of leukotriene C4 to rat lung fibroblasts and stimulation of collagen synthesis in vitro. Biochemistry 27(8), 2846-2853 (1988).
    • (1988) Biochemistry , vol.27 , Issue.8 , pp. 2846-2853
    • Phan, S.H.1    McGarry, B.M.2    Loeffler, K.M.3    Kunkel, S.L.4
  • 79
    • 35448988114 scopus 로고    scopus 로고
    • Molecular targets in pulmonary fibrosis: The myofibroblast in focus
    • Scotton CJ, Chambers RC. Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest 132(4), 1311-1321 (2007).
    • (2007) Chest , vol.132 , Issue.4 , pp. 1311-1321
    • Scotton, C.J.1    Chambers, R.C.2
  • 80
    • 33746494050 scopus 로고    scopus 로고
    • Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis
    • Kisseleva T, Uchinami H, Feirt N, et al. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. J. Hepatol. 45(3), 429-438 (2006).
    • (2006) J. Hepatol , vol.45 , Issue.3 , pp. 429-438
    • Kisseleva, T.1    Uchinami, H.2    Feirt, N.3
  • 81
    • 84865824048 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: An altered fibroblast proliferation linked to cancer biology
    • Vancheri C. Idiopathic pulmonary fibrosis: an altered fibroblast proliferation linked to cancer biology. Proc. Am. Thorac Soc. 9(3), 153-157 (2012).
    • (2012) Proc. Am. Thorac Soc , vol.9 , Issue.3 , pp. 153-157
    • Vancheri, C.1
  • 82
    • 73549104820 scopus 로고    scopus 로고
    • Connective tissue growth factor (CTGF, CCN2) gene regulation: A potent clinical bio-marker of fibroproliferative disease?
    • Leask A, Parapuram SK, Shi-Wen X, Abraham DJ. Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease? J. Cell Commun. Signal. 3(2), 89-94 (2009).
    • (2009) J. Cell Commun. Signal , vol.3 , Issue.2 , pp. 89-94
    • Leask, A.1    Parapuram, S.K.2    Shi-Wen, X.3    Abraham, D.J.4
  • 83
    • 84871320910 scopus 로고    scopus 로고
    • Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
    • Naik PK, Bozyk PD, Bentley JK, et al. Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis. Am. J. Physiol. Lung Cell Mol. Physiol. 303(12), L1046-L1056 (2012).
    • (2012) Am. J. Physiol. Lung Cell Mol. Physiol , vol.303 , Issue.12
    • Naik, P.K.1    Bozyk, P.D.2    Bentley, J.K.3
  • 84
    • 20444397431 scopus 로고    scopus 로고
    • Identification of bronchioalveolar stem cells in normal lung and lung cancer
    • Kim CF, Jackson EL, Woolfenden AE, et al. Identification of bronchioalveolar stem cells in normal lung and lung cancer. Cell 121(6), 823-835 (2005).
    • (2005) Cell , vol.121 , Issue.6 , pp. 823-835
    • Kim, C.F.1    Jackson, E.L.2    Woolfenden, A.E.3
  • 85
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins EL, Okubo T, Xue Y, et al. The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell 4(6), 525-534 (2009).
    • (2009) Cell Stem Cell , vol.4 , Issue.6 , pp. 525-534
    • Rawlins, E.L.1    Okubo, T.2    Xue, Y.3
  • 86
    • 33744924735 scopus 로고    scopus 로고
    • Role of epithelial cells in idiopathic pulmonary fibrosis: From innocent targets to serial killers
    • Selman M, Pardo A. Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. Proc. Am. Thorac Soc. 3(4), 364-372 (2006).
    • (2006) Proc. Am. Thorac Soc , vol.3 , Issue.4 , pp. 364-372
    • Selman, M.1    Pardo, A.2
  • 87
    • 76749165460 scopus 로고    scopus 로고
    • Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis
    • Sisson TH, Mendez M, Choi K, et al. Targeted injury of type II alveolar epithelial cells induces pulmonary fibrosis. Am. J. Respir. Crit. Care Med. 181(3), 254-263 (2010).
    • (2010) Am. J. Respir. Crit. Care Med , vol.181 , Issue.3 , pp. 254-263
    • Sisson, T.H.1    Mendez, M.2    Choi, K.3
  • 88
    • 0033862955 scopus 로고    scopus 로고
    • Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor
    • Wang R, Ibarra-Sunga O, Verlinski L, Pick R, Uhal BD. Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor. Am. J. Physiol. Lung Cell Mol. Physiol. 279(1), L143-L151 (2000).
    • (2000) Am. J. Physiol. Lung Cell Mol. Physiol , vol.279 , Issue.1
    • Wang, R.1    Ibarra-Sunga, O.2    Verlinski, L.3    Pick, R.4    Uhal, B.D.5
  • 89
    • 0037097680 scopus 로고    scopus 로고
    • TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells
    • Hagimoto N, Kuwano K, Inoshima I, et al. TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J. Immunol. 168(12), 6470-6478 (2002).
    • (2002) J. Immunol , vol.168 , Issue.12 , pp. 6470-6478
    • Hagimoto, N.1    Kuwano, K.2    Inoshima, I.3
  • 90
    • 68549136903 scopus 로고    scopus 로고
    • Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair
    • Rawlins EL, Okubo T, Que J, et al. Epithelial stem/progenitor cells in lung postnatal growth, maintenance, and repair. Cold Spring Harb. Symp. Quant. Biol. 73, 291-295 (2008).
    • (2008) Cold Spring Harb. Symp. Quant. Biol , vol.73 , pp. 291-295
    • Rawlins, E.L.1    Okubo, T.2    Que, J.3
  • 91
    • 34047156273 scopus 로고    scopus 로고
    • Stem cells and chronic lung disease
    • Gomperts BN, Strieter RM. Stem cells and chronic lung disease. Annu. Rev. Med. 58, 285-298 (2007).
    • (2007) Annu. Rev. Med , vol.58 , pp. 285-298
    • Gomperts, B.N.1    Strieter, R.M.2
  • 94
    • 81855175868 scopus 로고    scopus 로고
    • Peripheral blood fibrocytes: Enhancement of wound healing by cell proliferation, re-epithelialization, contraction, and angiogenesis
    • Kao HK, Chen B, Murphy GF, Li Q, Orgill DP, Guo L. Peripheral blood fibrocytes: enhancement of wound healing by cell proliferation, re-epithelialization, contraction, and angiogenesis. Ann. Surg. 254(6), 1066-1074 (2011).
    • (2011) Ann. Surg , vol.254 , Issue.6 , pp. 1066-1074
    • Kao, H.K.1    Chen, B.2    Murphy, G.F.3    Li, Q.4    Orgill, D.P.5    Guo, L.6
  • 95
    • 84874700441 scopus 로고    scopus 로고
    • Keratinocyte growth factor and dexamethasone plus elevated cAMP levels synergistically support pluripotent stem cell differentiation into alveolar epithelial type II cells
    • Schmeckebier S, Mauritz C, Katsirntaki K, et al. Keratinocyte growth factor and dexamethasone plus elevated cAMP levels synergistically support pluripotent stem cell differentiation into alveolar epithelial type II cells. Tissue Eng. Part A 19(7-8), 938-951 (2013).
    • (2013) Tissue Eng. Part A , vol.19 , Issue.7-8 , pp. 938-951
    • Schmeckebier, S.1    Mauritz, C.2    Katsirntaki, K.3
  • 96
    • 84873020006 scopus 로고    scopus 로고
    • FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration
    • Takase HM, Itoh T, Ino S, et al. FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 27(2), 169-181 (2013).
    • (2013) Genes Dev , vol.27 , Issue.2 , pp. 169-181
    • Takase, H.M.1    Itoh, T.2    Ino, S.3
  • 97
    • 81055125652 scopus 로고    scopus 로고
    • Programmed cell death in animal development and disease
    • Fuchs Y, Steller H. Programmed cell death in animal development and disease. Cell 147(4), 742-758 (2011).
    • (2011) Cell , vol.147 , Issue.4 , pp. 742-758
    • Fuchs, Y.1    Steller, H.2
  • 98
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • Kim KK, Kugler MC, Wolters PJ, et al. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc. Natl Acad. Sci. USA 103(35), 13180-13185 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.35 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3
  • 99
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133(4), 704-715 (2008).
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3
  • 100
    • 51449085561 scopus 로고    scopus 로고
    • Generation of breast cancer stem cells through epithelial-mesenchymal transition
    • Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE 3(8), e2888 (2008).
    • (2008) PLoS ONE , vol.3 , Issue.8
    • Morel, A.P.1    Lievre, M.2    Thomas, C.3    Hinkal, G.4    Ansieau, S.5    Puisieux, A.6
  • 101
    • 0346724511 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and its implications for fibrosis
    • Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J. Clin. Invest. 112(12), 1776-1784 (2003).
    • (2003) J. Clin. Invest , vol.112 , Issue.12 , pp. 1776-1784
    • Kalluri, R.1    Neilson, E.G.2
  • 102
    • 12944260524 scopus 로고    scopus 로고
    • Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes
    • Savagner P, Kusewitt DF, Carver EA, et al. Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J. Cell Physiol. 202(3), 858-866 (2005).
    • (2005) J. Cell Physiol , vol.202 , Issue.3 , pp. 858-866
    • Savagner, P.1    Kusewitt, D.F.2    Carver, E.A.3
  • 103
    • 84872463518 scopus 로고    scopus 로고
    • Detection of alveolar fibrocytes in idiopathic pulmonary fibrosis and systemic sclerosis
    • Borie R, Quesnel C, Phin S, et al. Detection of alveolar fibrocytes in idiopathic pulmonary fibrosis and systemic sclerosis. PLoS ONE 8(1), e53736 (2013).
    • (2013) PLoS ONE , vol.8 , Issue.1
    • Borie, R.1    Quesnel, C.2    Phin, S.3
  • 104
    • 27744574700 scopus 로고    scopus 로고
    • Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1
    • Fontana L, Chen Y, Prijatelj P, et al. Fibronectin is required for integrin alphavbeta6-mediated activation of latent TGF-beta complexes containing LTBP-1. FASEB J. 19(13), 1798 (2005).
    • (2005) FASEB J. , vol.19 , Issue.13 , pp. 1798
    • Fontana, L.1    Chen, Y.2    Prijatelj, P.3
  • 105
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger JS, Huang X, Kawakatsu H, et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 96(3), 319-328 (1999).
    • (1999) Cell , vol.96 , Issue.3 , pp. 319-328
    • Munger, J.S.1    Huang, X.2    Kawakatsu, H.3
  • 106
    • 84880837053 scopus 로고    scopus 로고
    • Adoptive transfer of fibrocytes enhances splenic T-cell numbers and survival in septic peritonitis
    • Nemzek JA, Fry C, Moore BB. Adoptive transfer of fibrocytes enhances splenic T-cell numbers and survival in septic peritonitis. Shock 40(2), 106-114 (2013).
    • (2013) Shock , vol.40 , Issue.2 , pp. 106-114
    • Nemzek, J.A.1    Fry, C.2    Moore, B.B.3
  • 107
    • 1642333177 scopus 로고    scopus 로고
    • Protection from fluorescein isothiocyanate-induced fibrosis in IL-13- deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts
    • Kolodsick JE, Toews GB, Jakubzick C, et al. Protection from fluorescein isothiocyanate-induced fibrosis in IL-13- deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts. J. Immunol. 172(7), 4068-4076 (2004).
    • (2004) J. Immunol , vol.172 , Issue.7 , pp. 4068-4076
    • Kolodsick, J.E.1    Toews, G.B.2    Jakubzick, C.3
  • 108
    • 84863798325 scopus 로고    scopus 로고
    • Angiogenesis in pulmonary fibrosis: Too much or not enough?
    • Hanumegowda C, Farkas L, Kolb M. Angiogenesis in pulmonary fibrosis: too much or not enough? Chest 142(1), 200-207 (2012).
    • (2012) Chest , vol.142 , Issue.1 , pp. 200-207
    • Hanumegowda, C.1    Farkas, L.2    Kolb, M.3
  • 109
    • 33744919279 scopus 로고    scopus 로고
    • Chemokine/ cytokine cocktail in idiopathic pulmonary fibrosis
    • Agostini C, Gurrieri C. Chemokine/ cytokine cocktail in idiopathic pulmonary fibrosis. Proc. Am. Thorac Soc. 3(4), 357-363 (2006).
    • (2006) Proc. Am. Thorac Soc , vol.3 , Issue.4 , pp. 357-363
    • Agostini, C.1    Gurrieri, C.2
  • 110
    • 12744262853 scopus 로고    scopus 로고
    • CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling
    • Burdick MD, Murray LA, Keane MP, et al. CXCL11 attenuates bleomycin-induced pulmonary fibrosis via inhibition of vascular remodeling. Am. J. Respir. Crit. Care Med. 171(3), 261-268 (2005).
    • (2005) Am. J. Respir. Crit. Care Med , vol.171 , Issue.3 , pp. 261-268
    • Burdick, M.D.1    Murray, L.A.2    Keane, M.P.3
  • 111
    • 84877854763 scopus 로고    scopus 로고
    • Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats
    • Wan YY, Tian GY, Guo HS, et al. Endostatin, an angiogenesis inhibitor, ameliorates bleomycin-induced pulmonary fibrosis in rats. Respir. Res. 14(1), 56 (2013).
    • (2013) Respir. Res , vol.14 , Issue.1 , pp. 56
    • Wan, Y.Y.1    Tian, G.Y.2    Guo, H.S.3
  • 112
    • 77955481200 scopus 로고    scopus 로고
    • Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis
    • Hashimoto N, Phan SH, Imaizumi K, et al. Endothelial-mesenchymal transition in bleomycin-induced pulmonary fibrosis. Am. J. Respir. Cell Mol. Biol. 43(2), 161-172 (2010).
    • (2010) Am. J. Respir. Cell Mol. Biol , vol.43 , Issue.2 , pp. 161-172
    • Hashimoto, N.1    Phan, S.H.2    Imaizumi, K.3
  • 113
    • 34547676391 scopus 로고    scopus 로고
    • Endothelial-to-mesenchymal transition contributes to cardiac fibrosis
    • Zeisberg EM, Tarnavski O, Zeisberg M, et al. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat. Med. 13(8), 952-961 (2007).
    • (2007) Nat. Med , vol.13 , Issue.8 , pp. 952-961
    • Zeisberg, E.M.1    Tarnavski, O.2    Zeisberg, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.