Inhibiting CXCL12 blocks fibrocyte migration and differentiation and attenuates bronchiolitis obliterans in a murine heterotopic tracheal transplant model

Journal of Thoracic and Cardiovascular Surgery

Volumn 145, Issue 3, 2013, Pages 854-861

  Harris, David A ^a   Zhao, Yunge ^a   Lapar, Damien J ^a   Emaminia, Abbas ^a   Steidle, John F ^a   Stoler, Mark ^a   Linden, Joel ^b   Kron, Irving L ^a   Lau, Christine L ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD45 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; COLLAGEN TYPE 1; IMMUNOGLOBULIN F(AB')2 FRAGMENT;

ALLOGRAFT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BONE MARROW BUFFY COAT; BRONCHIOLITIS OBLITERANS; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MIGRATION; CELL POPULATION; CELL SUSPENSION; CONTROLLED STUDY; DENSITOMETRY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG TRANSPLANTATION; MIGRATION INHIBITION; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; RECEPTOR BLOCKING; TRACHEA; TRACHEA GRAFT;

ANIMALS; BLOOD BUFFY COAT; BONE MARROW; BRONCHIOLITIS OBLITERANS; CELL DIFFERENTIATION; CELL MOVEMENT; CHEMOKINE CXCL12; DISEASE MODELS, ANIMAL; FIBROBLASTS; FIBROSIS; FLOW CYTOMETRY; MICE; MICE, INBRED BALB C; RECEPTORS, CXCR4; STAINING AND LABELING; STATISTICS, NONPARAMETRIC; TRACHEA; TRANSPLANTATION, HETEROTOPIC; TRANSPLANTATION, HOMOLOGOUS;

EID: 84873999799     PISSN: 00225223     EISSN: 1097685X     Source Type: Journal    
DOI: 10.1016/j.jtcvs.2012.03.079     Document Type: Article

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