A plausible model for bimodal p53 switch in DNA damage response

FEBS Letters

Volumn 588, Issue 5, 2014, Pages 815-821

  Sun, Tingzhe ^a   Cui, Jun ^b  

^a ANQING NORMAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Bimodal switch; Cell fate decision; Feedback loop; Monotonic increasing; p53 Pulse

Indexed keywords

DNA; ETOPOSIDE; MESSENGER RNA; PROTEIN MDM2; PROTEIN P53;

ARTICLE; BIMODAL SWITCH; CELL FATE; DNA DAMAGE; FEEDBACK SYSTEM; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS; SIMULATION; UBIQUITINATION;

BIMODAL SWITCH; CELL FATE DECISION; FEEDBACK LOOP; MONOTONIC INCREASING; P53 PULSE;

ALGORITHMS; COMPUTER SIMULATION; DNA DAMAGE; DNA REPAIR; FEEDBACK, PHYSIOLOGICAL; GENE EXPRESSION REGULATION; HUMANS; MODELS, BIOLOGICAL; PROTEIN STABILITY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84896740022     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.01.044     Document Type: Article

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