Metabolic QTL Analysis Links Chloroquine Resistance in Plasmodium falciparum to Impaired Hemoglobin Catabolism

PLoS Genetics

Volumn 10, Issue 1, 2014, Pages

  Lewis, Ian A ^a   Wacker, Mark ^b   Olszewski, Kellen L ^a,c   Cobbold, Simon A ^a   Baska, Katelynn S ^a   Tan, Asako ^b   Ferdig, Michael T ^b   Llinás, Manuel ^a,d  

^a PRINCETON UNIVERSITY   (United States)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c Kadmon Corporation   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; HEMOGLOBIN;

ANTIMALARIAL DRUG RESISTANCE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC CROSS; GENETIC LINKAGE; GENOTYPE; METABOLOMICS; NONHUMAN; PEPTIDOMICS; PFCRT GENE; PHENOTYPE; PLASMODIUM FALCIPARUM; PROGENY; PROTEIN DEGRADATION; PROTEIN METABOLISM; QUANTITATIVE TRAIT LOCUS;

ANTIMALARIALS; CHLOROQUINE; CHROMOSOME MAPPING; DRUG RESISTANCE; HEMOGLOBINS; HUMANS; MALARIA, FALCIPARUM; MEMBRANE TRANSPORT PROTEINS; METABOLISM; PEPTIDES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; QUANTITATIVE TRAIT LOCI;

EID: 84896724410     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004085     Document Type: Article

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