-
1
-
-
79961240592
-
Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets
-
Yuan J, et al. (2011) Chemical genomic profiling for antimalarial therapies, response signatures, and molecular targets. Science 333(6043):724-729.
-
(2011)
Science
, vol.333
, Issue.6043
, pp. 724-729
-
-
Yuan, J.1
-
2
-
-
0036152532
-
Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins
-
Krugliak M, Zhang J, Ginsburg H (2002) Intraerythrocytic Plasmodium falciparum utilizes only a fraction of the amino acids derived from the digestion of host cell cytosol for the biosynthesis of its proteins. Mol Biochem Parasitol 119(2):249-256.
-
(2002)
Mol Biochem Parasitol
, vol.119
, Issue.2
, pp. 249-256
-
-
Krugliak, M.1
Zhang, J.2
Ginsburg, H.3
-
3
-
-
80053336043
-
Falcipains and other cysteine proteases of malaria parasites
-
Rosenthal PJ (2011) Falcipains and other cysteine proteases of malaria parasites. Adv Exp Med Biol 712:30-48.
-
(2011)
Adv Exp Med Biol
, vol.712
, pp. 30-48
-
-
Rosenthal, P.J.1
-
4
-
-
5644247394
-
A Plasmodium falciparum dipeptidyl aminopeptidase i participates in vacuolar hemoglobin degradation
-
Klemba M, Gluzman I, Goldberg DE (2004) A Plasmodium falciparum dipeptidyl aminopeptidase I participates in vacuolar hemoglobin degradation. J Biol Chem 279(41):43000-43007.
-
(2004)
J Biol Chem
, vol.279
, Issue.41
, pp. 43000-43007
-
-
Klemba, M.1
Gluzman, I.2
Goldberg, D.E.3
-
5
-
-
0001133973
-
Unsaturated lipide oxidation catalyzed by hematin compounds
-
Tappel AL (1955) Unsaturated lipide oxidation catalyzed by hematin compounds. J Biol Chem 217(2):721-733.
-
(1955)
J Biol Chem
, vol.217
, Issue.2
, pp. 721-733
-
-
Tappel, A.L.1
-
6
-
-
0021322523
-
Hemin-mediated oxidative degradation of proteins
-
Aft RL, Mueller GC (1984) Hemin-mediated oxidative degradation of proteins. J Biol Chem 259(1):301-305.
-
(1984)
J Biol Chem
, vol.259
, Issue.1
, pp. 301-305
-
-
Aft, R.L.1
Mueller, G.C.2
-
7
-
-
0021100151
-
Hemin-mediated DNA strand scission
-
Aft RL, Mueller GC (1983) Hemin-mediated DNA strand scission. J Biol Chem 258(19): 12069-12072.
-
(1983)
J Biol Chem
, vol.258
, Issue.19
, pp. 12069-12072
-
-
Aft, R.L.1
Mueller, G.C.2
-
8
-
-
27544459459
-
Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus
-
Oliveira MF, et al. (2005) Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus. FEBS Lett 579(27): 6010-6016.
-
(2005)
FEBS Lett
, vol.579
, Issue.27
, pp. 6010-6016
-
-
Oliveira, M.F.1
-
9
-
-
42049124049
-
Recent advances in understanding the mechanism of hemozoin (malaria pigment) formation
-
Egan TJ (2008) Recent advances in understanding the mechanism of hemozoin (malaria pigment) formation. J Inorg Biochem 102(5-6):1288-1299.
-
(2008)
J Inorg Biochem
, vol.102
, Issue.5-6
, pp. 1288-1299
-
-
Egan, T.J.1
-
10
-
-
38149035199
-
Haemozoin formation
-
Egan TJ (2008) Haemozoin formation. Mol Biochem Parasitol 157(2):127-136.
-
(2008)
Mol Biochem Parasitol
, vol.157
, Issue.2
, pp. 127-136
-
-
Egan, T.J.1
-
11
-
-
0028947372
-
Malarial haemozoin/ β-haematin supports haem polymerization in the absence of protein
-
Dorn A, Stoffel R, Matile H, Bubendorf A, Ridley RG (1995) Malarial haemozoin/ β-haematin supports haem polymerization in the absence of protein. Nature 374(6519): 269-271.
-
(1995)
Nature
, vol.374
, Issue.6519
, pp. 269-271
-
-
Dorn, A.1
Stoffel, R.2
Matile, H.3
Bubendorf, A.4
Ridley, R.G.5
-
12
-
-
0028883915
-
Haem polymerization in malaria
-
Bendrat K, Berger BJ, Cerami A (1995) Haem polymerization in malaria. Nature 378(6553):138-139.
-
(1995)
Nature
, vol.378
, Issue.6553
, pp. 138-139
-
-
Bendrat, K.1
Berger, B.J.2
Cerami, A.3
-
13
-
-
33846945465
-
The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization
-
Pisciotta JM, et al. (2007) The role of neutral lipid nanospheres in Plasmodium falciparum haem crystallization. Biochem J 402(1):197-204.
-
(2007)
Biochem J
, vol.402
, Issue.1
, pp. 197-204
-
-
Pisciotta, J.M.1
-
14
-
-
43049134137
-
HDP-A novel heme detoxification protein from the malaria parasite
-
Jani D, et al. (2008) HDP-a novel heme detoxification protein from the malaria parasite. PLoS Pathog 4(4):e1000053.
-
(2008)
PLoS Pathog
, vol.4
, Issue.4
-
-
Jani, D.1
-
15
-
-
0037015614
-
Genome sequence of the human malaria parasite Plasmodium falciparum
-
Gardner MJ, et al. (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419(6906):498-511.
-
(2002)
Nature
, vol.419
, Issue.6906
, pp. 498-511
-
-
Gardner, M.J.1
-
17
-
-
16044372680
-
On the molecular mechanism of chloroquine's antimalarial action
-
Sullivan DJ, Jr., Gluzman IY, Russell DG, Goldberg DE (1996) On the molecular mechanism of chloroquine's antimalarial action. Proc Natl Acad Sci USA 93(21): 11865-11870.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.21
, pp. 11865-11870
-
-
Sullivan Jr., D.J.1
Gluzman, I.Y.2
Russell, D.G.3
Goldberg, D.E.4
-
18
-
-
33947330441
-
Artemisinin and chloroquine: Do mode of action and mechanism of resistance involve the same protagonists?
-
Lelièvre J, Berry A, Benoit-Vical F (2007) Artemisinin and chloroquine: Do mode of action and mechanism of resistance involve the same protagonists? Curr Opin Investig Drugs 8(2):117-124.
-
(2007)
Curr Opin Investig Drugs
, vol.8
, Issue.2
, pp. 117-124
-
-
Lelièvre, J.1
Berry, A.2
Benoit-Vical, F.3
-
19
-
-
0030051699
-
Second-generation antimalarial endoperoxides
-
Meshnick SR, Jefford CW, Posner GH, Avery MA, Peters W (1996) Second-generation antimalarial endoperoxides. Parasitol Today 12(2):79-82.
-
(1996)
Parasitol Today
, vol.12
, Issue.2
, pp. 79-82
-
-
Meshnick, S.R.1
Jefford, C.W.2
Posner, G.H.3
Avery, M.A.4
Peters, W.5
-
20
-
-
32644476297
-
Plasmodium falciparum: Biochemical characterization of the cysteine protease falcipain-2'
-
Singh N, Sijwali PS, Pandey KC, Rosenthal PJ (2006) Plasmodium falciparum: Biochemical characterization of the cysteine protease falcipain-2'. Exp Parasitol 112(3): 187-192.
-
(2006)
Exp Parasitol
, vol.112
, Issue.3
, pp. 187-192
-
-
Singh, N.1
Sijwali, P.S.2
Pandey, K.C.3
Rosenthal, P.J.4
-
21
-
-
0031713287
-
Role for the plasmodium falciparum digestive vacuole in chloroquine resistance
-
Saliba KJ, Folb PI, Smith PJ (1998) Role for the plasmodium falciparum digestive vacuole in chloroquine resistance. Biochem Pharmacol 56(3):313-320.
-
(1998)
Biochem Pharmacol
, vol.56
, Issue.3
, pp. 313-320
-
-
Saliba, K.J.1
Folb, P.I.2
Smith, P.J.3
-
22
-
-
0031691453
-
Antimalarial synergy of cysteine and aspartic protease inhibitors
-
Semenov A, Olson JE, Rosenthal PJ (1998) Antimalarial synergy of cysteine and aspartic protease inhibitors. Antimicrob Agents Chemother 42(9):2254-2258.
-
(1998)
Antimicrob Agents Chemother
, vol.42
, Issue.9
, pp. 2254-2258
-
-
Semenov, A.1
Olson, J.E.2
Rosenthal, P.J.3
-
23
-
-
12744262976
-
Cysteine proteases of malaria parasites
-
Rosenthal PJ (2004) Cysteine proteases of malaria parasites. Int J Parasitol 34(13-14): 1489-1499.
-
(2004)
Int J Parasitol
, vol.34
, Issue.13-14
, pp. 1489-1499
-
-
Rosenthal, P.J.1
-
24
-
-
0034666133
-
Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum
-
Shenai BR, Sijwali PS, Singh A, Rosenthal PJ (2000) Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum. J Biol Chem 275(37):29000-29010.
-
(2000)
J Biol Chem
, vol.275
, Issue.37
, pp. 29000-29010
-
-
Shenai, B.R.1
Sijwali, P.S.2
Singh, A.3
Rosenthal, P.J.4
-
25
-
-
0032942185
-
Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria
-
Fitch CD, Cai GZ, Chen YF, Shoemaker JD (1999) Involvement of lipids in ferriprotoporphyrin IX polymerization in malaria. Biochim Biophys Acta 1454(1):31-37.
-
(1999)
Biochim Biophys Acta
, vol.1454
, Issue.1
, pp. 31-37
-
-
Fitch, C.D.1
Cai, G.Z.2
Chen, Y.F.3
Shoemaker, J.D.4
-
26
-
-
21544442303
-
The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif
-
Pandey KC, et al. (2005) The Plasmodium falciparum cysteine protease falcipain-2 captures its substrate, hemoglobin, via a unique motif. Proc Natl Acad Sci USA 102(26): 9138-9143.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.26
, pp. 9138-9143
-
-
Pandey, K.C.1
-
27
-
-
70349146697
-
Synthetic Plasmodium-like hemozoin activates the immune response: A morphology - Function study
-
Jaramillo M, et al. (2009) Synthetic Plasmodium-like hemozoin activates the immune response: A morphology - function study. PLoS ONE 4(9):e6957.
-
(2009)
PLoS ONE
, vol.4
, Issue.9
-
-
Jaramillo, M.1
-
28
-
-
0035871063
-
Mechanism of malarial haem detoxification inhibition by chloroquine
-
Pandey AV, et al. (2001) Mechanism of malarial haem detoxification inhibition by chloroquine. Biochem J 355(Pt 2):333-338.
-
(2001)
Biochem J
, vol.355
, Issue.PART. 2
, pp. 333-338
-
-
Pandey, A.V.1
-
29
-
-
79960992639
-
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion
-
Klonis N, et al. (2011) Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion. Proc Natl Acad Sci USA 108(28):11405-11410.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.28
, pp. 11405-11410
-
-
Klonis, N.1
-
30
-
-
0036009325
-
Heme-artemisinin adducts are crucial mediators of the ability of artemisinin to inhibit heme polymerization
-
Kannan R, Sahal D, Chauhan VS (2002) Heme-artemisinin adducts are crucial mediators of the ability of artemisinin to inhibit heme polymerization. Chem Biol 9(3): 321-332.
-
(2002)
Chem Biol
, vol.9
, Issue.3
, pp. 321-332
-
-
Kannan, R.1
Sahal, D.2
Chauhan, V.S.3
-
31
-
-
79954421201
-
Plasmodium vivax: Collaborative roles for plasmepsin 4 and vivapains in hemoglobin hydrolysis
-
Moon SU, et al. (2011) Plasmodium vivax: Collaborative roles for plasmepsin 4 and vivapains in hemoglobin hydrolysis. Exp Parasitol 128(2):127-132.
-
(2011)
Exp Parasitol
, vol.128
, Issue.2
, pp. 127-132
-
-
Moon, S.U.1
-
32
-
-
0037021386
-
Theories on malarial pigment formation and quinoline action
-
Sullivan DJ (2002) Theories on malarial pigment formation and quinoline action. Int J Parasitol 32(13):1645-1653.
-
(2002)
Int J Parasitol
, vol.32
, Issue.13
, pp. 1645-1653
-
-
Sullivan, D.J.1
-
33
-
-
33745041171
-
Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems
-
Liu J, Istvan ES, Gluzman IY, Gross J, Goldberg DE (2006) Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems. Proc Natl Acad Sci USA 103(23):8840-8845.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.23
, pp. 8840-8845
-
-
Liu, J.1
Istvan, E.S.2
Gluzman, I.Y.3
Gross, J.4
Goldberg, D.E.5
-
34
-
-
34250620398
-
Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function
-
Bonilla JA, Bonilla TD, Yowell CA, Fujioka H, Dame JB (2007) Critical roles for the digestive vacuole plasmepsins of Plasmodium falciparum in vacuolar function. Mol Microbiol 65(1):64-75.
-
(2007)
Mol Microbiol
, vol.65
, Issue.1
, pp. 64-75
-
-
Bonilla, J.A.1
Bonilla, T.D.2
Yowell, C.A.3
Fujioka, H.4
Dame, J.B.5
-
35
-
-
0001793063
-
Preparation of haemoglobin crystals
-
Perutz MF (1968) Preparation of haemoglobin crystals. J Cryst Growth 2:54-56.
-
(1968)
J Cryst Growth
, vol.2
, pp. 54-56
-
-
Perutz, M.F.1
|