-
1
-
-
40149096226
-
Post-transcriptional gene regulation by RNA-binding proteins during oxidative stress: Implications for cellular senescence
-
Abdelmohsen, K., Kuwano, Y., Kim, H. H., and Gorospe, M. (2008). Post-transcriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence. Biol Chem 389, 243-255.
-
(2008)
Biol Chem
, vol.389
, pp. 243-255
-
-
Abdelmohsen, K.1
Kuwano, Y.2
Kim, H.H.3
Gorospe, M.4
-
2
-
-
33847035824
-
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
-
Abdelmohsen, K., Pullmann, R. Jr., Lal, A., Kim, H. H., Galban, S., Yang, X., Blethrow, J. D., Walker, M., Shubert, J., Gillespie, D. A., Furneaux, H., and Gorospe, M. (2007a). Phosphorylation of HuR by Chk2 regulates SIRT1 expression. Mol Cell 25, 543-557.
-
(2007)
Mol Cell
, vol.25
, pp. 543-557
-
-
Abdelmohsen, K.1
Pullmann, R.2
Lal, A.3
Kim, H.H.4
Galban, S.5
Yang, X.6
Blethrow, J.D.7
Walker, M.8
Shubert, J.9
Gillespie, D.A.10
Furneaux, H.11
Gorospe, M.12
-
3
-
-
34547651351
-
Posttranscriptional orchestration of an anti-apoptotic program by HuR
-
Abdelmohsen, K., Lal, A., Kim, H. H., and Gorospe, M. (2007b). Posttranscriptional orchestration of an anti-apoptotic program by HuR. Cell Cycle 6, 1288-1292.
-
(2007)
Cell Cycle
, vol.6
, pp. 1288-1292
-
-
Abdelmohsen, K.1
Lal, A.2
Kim, H.H.3
Gorospe, M.4
-
4
-
-
0031783046
-
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation
-
Atasoy, U., Watson, J., Patel, D., and Keene, J. D. (1998). ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation. J Cell Sci 111, 3145-3156.
-
(1998)
J Cell Sci
, vol.111
, pp. 3145-3156
-
-
Atasoy, U.1
Watson, J.2
Patel, D.3
Keene, J.D.4
-
5
-
-
34249681337
-
P53: New roles in metabolism
-
Bensaad, K. and Vousden, K. H. (2007) p53: new roles in metabolism. Trends Cell Biol 17, 286-291.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 286-291
-
-
Bensaad, K.1
Vousden, K.H.2
-
6
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander, G. and Guarente, L. (2004). The Sir2 family of protein deacetylases. Annu Rev Biochem 73, 417-435.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
7
-
-
0034597057
-
Protein ligands to HuR modulate its interaction with target mRNAs in vivo
-
Brennan, C. M., Gallouzi, I. E., and Steitz, J. A. (2000). Protein ligands to HuR modulate its interaction with target mRNAs in vivo. J Cell Biol 151, 1-14.
-
(2000)
J Cell Biol
, vol.151
, pp. 1-14
-
-
Brennan, C.M.1
Gallouzi, I.E.2
Steitz, J.A.3
-
9
-
-
0037377060
-
Ubiquitination, phosphorylation and acetylation: The molecular basis for p53 regulation
-
Brooks, C. L. and Gu, W. (2003). Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol 15, 164-171.
-
(2003)
Curr Opin Cell Biol
, vol.15
, pp. 164-171
-
-
Brooks, C.L.1
Gu, W.2
-
10
-
-
31544457877
-
P53 ubiquitination: Mdm2 and beyond
-
Brooks, C. L. and Gu, W. (2006). p53 ubiquitination: Mdm2 and beyond. Mol Cell 21, 307-315.
-
(2006)
Mol Cell
, vol.21
, pp. 307-315
-
-
Brooks, C.L.1
Gu, W.2
-
11
-
-
46349098382
-
Regulation of apoptosis by the redox state of cytochrome c
-
Brown, G. C. and Borutaite, V. (2008). Regulation of apoptosis by the redox state of cytochrome c. Biochim Biophys Acta 1777, 877-881.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 877-881
-
-
Brown, G.C.1
Borutaite, V.2
-
12
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004). Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
13
-
-
0032701521
-
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
-
Bunz, F., Hwang, P. M., Torrance, C., Waldman, T., Zhang, Y., Dillehay, L., Williams, J., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1999). Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest 104, 263-269.
-
(1999)
J Clin Invest
, vol.104
, pp. 263-269
-
-
Bunz, F.1
Hwang, P.M.2
Torrance, C.3
Waldman, T.4
Zhang, Y.5
Dillehay, L.6
Williams, J.7
Lengauer, C.8
Kinzler, K.W.9
Vogelstein, B.10
-
14
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., and Vogelstein, B. (1998). Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
15
-
-
30844469142
-
Cancer and aging: Yin, yang, and p53
-
2002
-
Campisi, J. (2002). Cancer and aging: yin, yang, and p53. Sci Aging Knowledge Environ 2002(1), pe1.
-
(2002)
Sci Aging Knowledge Environ
, Issue.1
, pp. pe1
-
-
Campisi, J.1
-
16
-
-
30844431744
-
HuR, an RNA-binding protein, involved in the control of cellular differentiation
-
Cherry, J., Karschner, V., Jones, H., Pekala, P. H. (2006). HuR, an RNA-binding protein, involved in the control of cellular differentiation. In Vivo 20, 17-23.
-
(2006)
Vivo
, vol.20
, pp. 17-23
-
-
Cherry, J.1
Karschner, V.2
Jones, H.3
Pekala, P.H.4
-
17
-
-
41149150219
-
The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
-
Chu, I. M., Hengst, L., and Slingerland, J. M. (2008). The Cdk inhibitor p27 in human cancer: prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 8, 253-267.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 253-267
-
-
Chu, I.M.1
Hengst, L.2
Slingerland, J.M.3
-
18
-
-
12144286529
-
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis
-
Cohen, H. Y., Lavu, S., Bitterman, K. J., Hekking, B., Imahiyerobo, T. A., Miller, C., Frye, R., Ploegh, H., Kessler, B. M., and Sinclair, D. A. (2004). Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis. Mol. Cell 13, 627-638.
-
(2004)
Mol. Cell
, vol.13
, pp. 627-638
-
-
Cohen, H.Y.1
Lavu, S.2
Bitterman, K.J.3
Hekking, B.4
Imahiyerobo, T.A.5
Miller, C.6
Frye, R.7
Ploegh, H.8
Kessler, B.M.9
Sinclair, D.A.10
-
19
-
-
0347601880
-
A decade of caspases
-
Degterev, A., Boyce, M., and Yuan, J. (2003). A decade of caspases. Oncogene 22, 8543-8567.
-
(2003)
Oncogene
, vol.22
, pp. 8543-8567
-
-
Degterev, A.1
Boyce, M.2
Yuan, J.3
-
20
-
-
0035213198
-
Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells
-
Dixon, D. A., Tolley, N. D., King, P. H., Nabors, L. B., McIntyre, T. M., Zimmerman, G. A., and Prescott, S. M. (2001). Altered expression of the mRNA stability factor HuR promotes cyclooxygenase-2 expression in colon cancer cells. J Clin Invest 108, 1657-1665.
-
(2001)
J Clin Invest
, vol.108
, pp. 1657-1665
-
-
Dixon, D.A.1
Tolley, N.D.2
King, P.H.3
Nabors, L.B.4
McIntyre, T.M.5
Zimmerman, G.A.6
Prescott, S.M.7
-
21
-
-
42149150455
-
Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
-
Doller, A., Akool, el-S., Huwiler, A., Müller, R., Radeke, H. H., Pfeilschifter, J., and Eberhardt, W. (2008). Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA. Mol Cell Biol 28, 2608-2625.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 2608-2625
-
-
Doller, A.1
Akool, E.-S.2
Huwiler, A.3
Müller, R.4
Radeke, H.H.5
Pfeilschifter, J.6
Eberhardt, W.7
-
22
-
-
34250362729
-
Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: Implications for posttranscriptional regulation of cyclooxygenase-2
-
Doller, A., Huwiler, A., Müller, R., Radeke, H. H., Pfeilschifter, J., and Eberhardt, W. (2007). Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. Mol Biol Cell 18, 2137-2148.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2137-2148
-
-
Doller, A.1
Huwiler, A.2
Müller, R.3
Radeke, H.H.4
Pfeilschifter, J.5
Eberhardt, W.6
-
23
-
-
0027312521
-
Differentiation-linked expression of prothymosin a gene in human myeloid leukemic cells
-
Dosil, M., Alvarez-Fernandez, L., and Gomez-Marquez, J. (1993). Differentiation-linked expression of prothymosin a gene in human myeloid leukemic cells. Exp Cell Res 204, 94-101.
-
(1993)
Exp Cell Res
, vol.204
, pp. 94-101
-
-
Dosil, M.1
Alvarez-Fernandez, L.2
Gomez-Marquez, J.3
-
24
-
-
0026099022
-
The MYC protein activates transcription of the a-prothymosin gene
-
Eilers, M., Schirm, S., and Bishop, J. M. (1991). The MYC protein activates transcription of the a-prothymosin gene. EMBO J 10, 133-141
-
(1991)
EMBO J
, vol.10
, pp. 133-141
-
-
Eilers, M.1
Schirm, S.2
Bishop, J.M.3
-
25
-
-
43049172179
-
MicroRNAs
-
Fabbri, M., Croce, C. M., and Calin, G. A. (2008). MicroRNAs. Cancer J 14, 1-6.
-
(2008)
Cancer J
, vol.14
, pp. 1-6
-
-
Fabbri, M.1
Croce, C.M.2
Calin, G.A.3
-
26
-
-
0032431026
-
HNS, a nuclear-cytoplasmic shuttling sequence in HuR
-
Fan, X. C. and Steitz, J. A. (1998). HNS, a nuclear-cytoplasmic shuttling sequence in HuR. Proc Natl Acad Sci USA 95, 15293-15298.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 15293-15298
-
-
Fan, X.C.1
Steitz, J.A.2
-
27
-
-
0037423932
-
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor
-
Fan, Z., Beresford, P. J., Oh, D. Y., Zhang, D., and Lieberman, J. (2003). Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor. Cell, 112, 659-672.
-
(2003)
Cell
, vol.112
, pp. 659-672
-
-
Fan, Z.1
Beresford, P.J.2
Oh, D.Y.3
Zhang, D.4
Lieberman, J.5
-
28
-
-
0038450334
-
Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes
-
Figueroa, A., Cuadrado, A., Fan, J., Atasoy, U., Muscat, G. E., Muoz-Canoves, P., Gorospe, M., and Muoz, A. (2003) Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes. Mol Cell Biol 23(14):4991-5004.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.14
, pp. 4991-5004
-
-
Figueroa, A.1
Cuadrado, A.2
Fan, J.3
Atasoy, U.4
Muscat, G.E.5
Muoz-Canoves, P.6
Gorospe, M.7
Muoz, A.8
-
29
-
-
0033887456
-
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
-
Frye, R. A. (2000). Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins. Biochem. Biophys Res Commun 273, 793-798.
-
(2000)
Biochem. Biophys Res Commun
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
30
-
-
33746886979
-
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
-
Fulda, S., and Debatin, K. M. (2006). Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25, 4798-4811
-
(2006)
Oncogene
, vol.25
, pp. 4798-4811
-
-
Fulda, S.1
Debatin, K.M.2
-
31
-
-
37549037125
-
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha
-
Galbán, S., Kuwano, Y., Pullmann, R. Jr., Martindale, J. L., Kim, H. H., Lal, A., Abdelmohsen, K., Yang, X., Dang, Y., Liu, J. O., Lewis, S. M., Holcik, M., and Gorospe, M. (2008). RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Mol Cell Biol 28, 93-107.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 93-107
-
-
Galbán, S.1
Kuwano, Y.2
Pullmann, R.3
Martindale, J.L.4
Kim, H.H.5
Lal, A.6
Abdelmohsen, K.7
Yang, X.8
Dang, Y.9
Liu, J.O.10
Lewis, S.M.11
Holcik, M.12
Gorospe, M.13
-
32
-
-
0034850959
-
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock
-
Gallouzi, I. E., Brennan, C. M., and Steitz, J. A. (2001). Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock. RNA 7, 1348-1361.
-
(2001)
RNA
, vol.7
, pp. 1348-1361
-
-
Gallouzi, I.E.1
Brennan, C.M.2
Steitz, J.A.3
-
33
-
-
0035976612
-
Delineation of mRNA export pathways by the use of cell-permeable peptides
-
Gallouzi, I. E. and Steitz, J. A. (2001). Delineation of mRNA export pathways by the use of cell-permeable peptides. Science. 294, 1895-901.
-
(2001)
Science
, vol.294
, pp. 1895-1901
-
-
Gallouzi, I.E.1
Steitz, J.A.2
-
34
-
-
2342573011
-
HuR in the mammalian genotoxic response: Post-transcriptional multitasking
-
Gorospe, M. (2003). HuR in the mammalian genotoxic response: post-transcriptional multitasking. Cell Cycle 2, 412-414.
-
(2003)
Cell Cycle
, vol.2
, pp. 412-414
-
-
Gorospe, M.1
-
35
-
-
0030902111
-
P21 (Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells
-
Gorospe, M., Cirielli, C., Wang, X., Seth, P., Capogrossi, M. C., and Holbrook, N. J. (1997). p21 (Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cells. Oncogene. 14, 929-935.
-
(1997)
Oncogene
, vol.14
, pp. 929-935
-
-
Gorospe, M.1
Cirielli, C.2
Wang, X.3
Seth, P.4
Capogrossi, M.C.5
Holbrook, N.J.6
-
36
-
-
0030024241
-
Role of p21 in prostaglandin A2-mediated cellular arrest and death
-
Gorospe, M. and Holbrook, N. J. (1996). Role of p21 in prostaglandin A2-mediated cellular arrest and death. Cancer Res 56, 475-479.
-
(1996)
Cancer Res
, vol.56
, pp. 475-479
-
-
Gorospe, M.1
Holbrook, N.J.2
-
37
-
-
0029956387
-
Protective role of p21 (Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells
-
Gorospe, M., Wang, X., Guyton, K. Z., and Holbrook, N. J. (1996). Protective role of p21 (Waf1/Cip1) against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells. Mol Cell Biol 16, 6654-6660.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6654-6660
-
-
Gorospe, M.1
Wang, X.2
Guyton, K.Z.3
Holbrook, N.J.4
-
38
-
-
0032780023
-
Functional role of p21 during the cellular response to stress
-
Gorospe, M., Wang, X., and Holbrook, N. J. (1999). Functional role of p21 during the cellular response to stress. Gene Expr 7, 377-385.
-
(1999)
Gene Expr
, vol.7
, pp. 377-385
-
-
Gorospe, M.1
Wang, X.2
Holbrook, N.J.3
-
39
-
-
20444430478
-
Apoptotic pathways: Ten minutes to dead
-
Green, D. R. (2005). Apoptotic pathways: ten minutes to dead. Cell 121, 671-674.
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
40
-
-
33748078455
-
HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells
-
Guo, X. and Hartley, R. S. (2006). HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells. Cancer Res 66, 7948-7956.
-
(2006)
Cancer Res
, vol.66
, pp. 7948-7956
-
-
Guo, X.1
Hartley, R.S.2
-
41
-
-
1542267816
-
Transportin2 functions as importin and mediates nuclear import of HuR
-
Güttinger, S., Mühlhäusser, P., Koller-Eichhorn, R., Brennecke, J., and Kutay, U. (2004) Transportin2 functions as importin and mediates nuclear import of HuR. Proc Natl Acad Sci USA 101, 2918-2923.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2918-2923
-
-
Güttinger, S.1
Mühlhäusser, P.2
Koller-Eichhorn, R.3
Brennecke, J.4
Kutay, U.5
-
42
-
-
0034641918
-
The biochemistry of apoptosis
-
Hengartner, M. O. (2000). The biochemistry of apoptosis. Nature 407, 770-776.
-
(2000)
Nature
, vol.407
, pp. 770-776
-
-
Hengartner, M.O.1
-
43
-
-
0041305878
-
The thymosins, Prothymosin alpha, Parathymosin, and beta-thymosins: Structure and function
-
Review
-
Hannappel, E. and Huff, T. (2003). The thymosins, Prothymosin alpha, Parathymosin, and beta-thymosins: structure and function. Vitam Horm 66, 257-96. Review.
-
(2003)
Vitam Horm
, vol.66
, pp. 257-296
-
-
Hannappel, E.1
Huff, T.2
-
44
-
-
22244472675
-
Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism
-
Higashino, F., Aoyagi, M., Takahashi, A., Ishino, M., Taoka, M., Isobe, T., Kobayashi, M., Totsuka, Y., Kohgo, T., and Shindoh, M. (2005). Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism. J Cell Biol 170, 15-20.
-
(2005)
J Cell Biol
, vol.170
, pp. 15-20
-
-
Higashino, F.1
Aoyagi, M.2
Takahashi, A.3
Ishino, M.4
Taoka, M.5
Isobe, T.6
Kobayashi, M.7
Totsuka, Y.8
Kohgo, T.9
Shindoh, M.10
-
45
-
-
2942532135
-
Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes
-
Hill, M. M., Adrain, C., Duriez, P. J., Creagh, E. M., and Martin, S. J. (2004). Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J 23, 2134-2145.
-
(2004)
EMBO J
, vol.23
, pp. 2134-2145
-
-
Hill, M.M.1
Adrain, C.2
Duriez, P.J.3
Creagh, E.M.4
Martin, S.J.5
-
46
-
-
34648824397
-
Genetic and molecular pathogenesis of mantle cell lymphoma: Perspectives for new targeted therapeutics
-
Jares, P., Colomer, D., and Campo, E. (2007). Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics. Nat Rev Cancer 7, 750-762.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 750-762
-
-
Jares, P.1
Colomer, D.2
Campo, E.3
-
47
-
-
0037428217
-
Distinctive roles of PHAP proteins and prothymosin-A in a death regulatory pathway
-
Jiang, X., Kim, H. E., Shu, H., Zhao, Y., Zhang, H., Kofron, J., Donnelly, J., Burns, D., Ng, S. C., Rosenberg, S., and Wang, X. (2003). Distinctive roles of PHAP proteins and prothymosin-a in a death regulatory pathway. Science 299, 223-226.
-
(2003)
Science
, vol.299
, pp. 223-226
-
-
Jiang, X.1
Kim, H.E.2
Shu, H.3
Zhao, Y.4
Zhang, H.5
Kofron, J.6
Donnelly, J.7
Burns, D.8
Ng, S.C.9
Rosenberg, S.10
Wang, X.11
-
48
-
-
33845648539
-
Cyclooxygenase-2 and tumor biology
-
Kanaoka, S., Takai, T., Yoshida, K. (2007). Cyclooxygenase-2 and tumor biology. Adv Clin Chem 43, 59-78.
-
(2007)
Adv Clin Chem
, vol.43
, pp. 59-78
-
-
Kanaoka, S.1
Takai, T.2
Yoshida, K.3
-
49
-
-
0031439355
-
Promoting apop-tosis: A novel activity associated with the cyclin-dependent kinase inhibitor p27
-
Katayose, Y., Kim, M., Rakkar, A. N., Li, Z., Cowan, K. H., and Seth, P. (1997). Promoting apop-tosis: a novel activity associated with the cyclin-dependent kinase inhibitor p27. Cancer Res 57, 5441-5445.
-
(1997)
Cancer Res
, vol.57
, pp. 5441-5445
-
-
Katayose, Y.1
Kim, M.2
Rakkar, A.N.3
Li, Z.4
Cowan, K.H.5
Seth, P.6
-
50
-
-
0036853914
-
Orchestrating the unfolded protein response in health and disease
-
Kaufman, R. J. (2002). Orchestrating the unfolded protein response in health and disease. J Clin Invest 110, 1389-1398.
-
(2002)
J Clin Invest
, vol.110
, pp. 1389-1398
-
-
Kaufman, R.J.1
-
51
-
-
0035575679
-
Programmed cell death: Alive and well in the new millennium
-
Kaufmann, S. H. and Hengartner, M. O. (2001). Programmed cell death: alive and well in the new millennium. Trends Cell Biol 11, 526-534
-
(2001)
Trends Cell Biol
, vol.11
, pp. 526-534
-
-
Kaufmann, S.H.1
Hengartner, M.O.2
-
52
-
-
33645824941
-
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR
-
Kawai, T., Lal, A., Yang, X., Galban, S., Mazan-Mamczarz, K., and Gorospe, M. (2006). Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR. Mol Cell Biol 26, 3295-3307.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3295-3307
-
-
Kawai, T.1
Lal, A.2
Yang, X.3
Galban, S.4
Mazan-Mamczarz, K.5
Gorospe, M.6
-
53
-
-
34250735674
-
RNA regulons: Coordination of post-transcriptional events
-
Keene, J. D. (2007). RNA regulons: coordination of post-transcriptional events. Nat Rev Genet 8, 533-543.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 533-543
-
-
Keene, J.D.1
-
54
-
-
46249130717
-
Nuclear HuR accumulation through phosphorylation by Cdk1
-
Kim, H. H., Abdelmohsen, K., Lal, A., Pullmann, R. Jr., Yang, X., Galban, S., Srikantan, S., Martindale, J. L., Blethrow, J., Shokat, K. M., and Gorospe, M. (2008a). Nuclear HuR accumulation through phosphorylation by Cdk1. Genes Dev 22, 1804-1815.
-
(2008)
Genes Dev
, vol.22
, pp. 1804-1815
-
-
Kim, H.H.1
Abdelmohsen, K.2
Lal, A.3
Pullmann, R.4
Yang, X.5
Galban, S.6
Srikantan, S.7
Martindale, J.L.8
Blethrow, J.9
Shokat, K.M.10
Gorospe, M.11
-
55
-
-
55849099956
-
Modification at HuR (S242) alters HuR localization and proliferative influence
-
Epub ahead of print PMID: 18948743
-
Kim, H. H., Yang, X., Kuwano, Y., and Gorospe, M. (2008b). Modification at HuR (S242) alters HuR localization and proliferative influence. Cell Cycle 7 [Epub ahead of print]PMID: 18948743
-
(2008)
Cell Cycle
, pp. 7
-
-
Kim, H.H.1
Yang, X.2
Kuwano, Y.3
Gorospe, M.4
-
56
-
-
54049111406
-
Phosphorylated HuR shuttles in cycles
-
Kim, H. H. and Gorospe M. (2008). Phosphorylated HuR shuttles in cycles. Cell Cycle 7, 3124-3126.
-
(2008)
Cell Cycle
, vol.7
, pp. 3124-3126
-
-
Kim, H.H.1
Gorospe, M.2
-
57
-
-
0036894711
-
ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR
-
Kullmann, M., Gopfert, U., Siewe, B., and Hengst, L. (2002). ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR. Genes Dev 16, 3087-3099.
-
(2002)
Genes Dev
, vol.16
, pp. 3087-3099
-
-
Kullmann, M.1
Gopfert, U.2
Siewe, B.3
Hengst, L.4
-
58
-
-
0035690330
-
Cyclooxygenase enzymes: Catalysis and inhibition
-
Kurumbail, R. G., Kiefer, J. R., and Marnett, L. J. (2001). Cyclooxygenase enzymes: catalysis and inhibition. Curr Opin Struct Biol 11, 752-760.
-
(2001)
Curr Opin Struct Biol
, vol.11
, pp. 752-760
-
-
Kurumbail, R.G.1
Kiefer, J.R.2
Marnett, L.J.3
-
59
-
-
47049116117
-
MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90
-
Kuwano, Y., Kim, H. H., Abdelmohsen, K., Pullmann, R. Jr., Martindale, J. L., Yang, X., and Gorospe, M. (2008). MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90. Mol Cell Biol 28, 4562-75.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 4562-4575
-
-
Kuwano, Y.1
Kim, H.H.2
Abdelmohsen, K.3
Pullmann, R.4
Martindale, J.L.5
Yang, X.6
Gorospe, M.7
-
60
-
-
50849100743
-
Protecting the stress response, guarding the MKP-1 mRNA
-
Kuwano, Y. and Gorospe, M. (2008). Protecting the stress response, guarding the MKP-1 mRNA. Cell Cycle 7, 2640-2642.
-
(2008)
Cell Cycle
, vol.7
, pp. 2640-2642
-
-
Kuwano, Y.1
Gorospe, M.2
-
61
-
-
0032474850
-
Developmental expression of AUF1 and HuR, two c-myc mRNA binding proteins
-
Lafon, I., Carballès, F., Brewer, G., Poiret, M., and Morello, D. (1998). Developmental expression of AUF1 and HuR, two c-myc mRNA binding proteins. Oncogene 16(26), 3413-21.
-
(1998)
Oncogene
, vol.16
, Issue.26
, pp. 3413-3421
-
-
Lafon, I.1
Carballès, F.2
Brewer, G.3
Poiret, M.4
Morello, D.5
-
62
-
-
4143122397
-
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
-
Epub 2004 Jul. 15
-
Lal, A., Mazan-Mamczarz, K., Kawai, T., Yang, X., Martindale, J. L., and Gorospe, M. (2004). Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs. EMBO J 23(15), 3092-102. Epub 2004 Jul. 15.
-
(2004)
EMBO J
, vol.23
, Issue.15
, pp. 3092-3102
-
-
Lal, A.1
Mazan-Mamczarz, K.2
Kawai, T.3
Yang, X.4
Martindale, J.L.5
Gorospe, M.6
-
63
-
-
20044366611
-
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha
-
Lal, A., Kawai, T., Yang, X., Mazan-Mamczarz, K., and Gorospe, M. (2005). Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha. EMBO J. 24, 1852-1862.
-
(2005)
EMBO J
, vol.24
, pp. 1852-1862
-
-
Lal, A.1
Kawai, T.2
Yang, X.3
Mazan-Mamczarz, K.4
Gorospe, M.5
-
64
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P, Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., Wang, X. (1997). Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
65
-
-
27744520451
-
HuR: Post-transcriptional paths to malignancy
-
López de Silanes, I., Lal, A., Gorospe, M. (2005). HuR: post-transcriptional paths to malignancy. RNA Biol 2, 11-3.
-
(2005)
RNA Biol
, vol.2
, pp. 11-13
-
-
López De Silanes, I.1
Lal, A.2
Gorospe, M.3
-
66
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo, J., Nikolaev, A. Y., Imai, S., Chen, D., Su, F., Shiloh, A., Guarente, L., and Gu, W. (2001). Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107, 137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
67
-
-
0033587731
-
Cancer dormancy and cell signaling: Induction of p21waf1 initiated by membrane IgM engagement increases survival of B lymphoma cells
-
Marches, R., Hsueh, R., and Uhr, J. W. (1999). Cancer dormancy and cell signaling: Induction of p21waf1 initiated by membrane IgM engagement increases survival of B lymphoma cells. Proc Natl Acad Sci USA 96, 8711-8715.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 8711-8715
-
-
Marches, R.1
Hsueh, R.2
Uhr, J.W.3
-
68
-
-
0037184910
-
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis
-
Martin, A. G., and Fearnhead, H. O. (2002). Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis. J Biol Chem 277, 50834-50841.
-
(2002)
J Biol Chem
, vol.277
, pp. 50834-50841
-
-
Martin, A.G.1
Fearnhead, H.O.2
-
69
-
-
2942534331
-
Apo cytochrome c inhibits cas-pases by preventing apoptosome formation
-
Martin, A. G., Nguyen, J., Wells, J. A., Fearnhead, H. O. (2004). Apo cytochrome c inhibits cas-pases by preventing apoptosome formation. Biochem Biophys Res Commun. 319, 944-950.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 944-950
-
-
Martin, A.G.1
Nguyen, J.2
Wells, J.A.3
Fearnhead, H.O.4
-
70
-
-
0038153919
-
RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation
-
Mazan-Mamczarz, K., Galban, S., López de Silanes, I., Martindale, J. L., Atasoy, U., Keene, J. D., and Gorospe, M. (2003). RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc Natl Acad Sci USA 100, 8354-8359.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8354-8359
-
-
Mazan-Mamczarz, K.1
Galban, S.2
López De Silanes, I.3
Martindale, J.L.4
Atasoy, U.5
Keene, J.D.6
Gorospe, M.7
-
71
-
-
38349047829
-
Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAPI regulation of apoptosis
-
Mazroui, R., Di Marco, S., Clair, E., von Roretz, C., Tenenbaum, S. A., Keene, J. D., Saleh, M., and Gallouzi, I. E. (2008). Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAPI regulation of apoptosis. J Cell Biol. 180, 113-127.
-
(2008)
J Cell Biol
, vol.180
, pp. 113-127
-
-
Mazroui, R.1
Di Marco, S.2
Clair, E.3
Von Roretz, C.4
Tenenbaum, S.A.5
Keene, J.D.6
Saleh, M.7
Gallouzi, I.E.8
-
72
-
-
34447532192
-
Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR
-
Meisner, N. C., Hintersteiner, M., Mueller, K., Bauer, R., Seifert, J. M., Naegeli, H. U., Ottl, J., Oberer, L., Guenat, C., Moss, S., Harrer, N., Woisetschlaeger, M., Buehler, C., Uhl, V., and Auer, M. (2007). Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR. Nat Chem Biol 3, 508-515.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 508-515
-
-
Meisner, N.C.1
Hintersteiner, M.2
Mueller, K.3
Bauer, R.4
Seifert, J.M.5
Naegeli, H.U.6
Ottl, J.7
Oberer, L.8
Guenat, C.9
Moss, S.10
Harrer, N.11
Woisetschlaeger, M.12
Buehler, C.13
Uhl, V.14
Auer, M.15
-
73
-
-
34547669249
-
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain
-
Mellert, H., Sykes, S. M., Murphy, M. E., McMahon, S. B. (2007). The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell Cycle 6, 1304-1306.
-
(2007)
Cell Cycle
, vol.6
, pp. 1304-1306
-
-
Mellert, H.1
Sykes, S.M.2
Murphy, M.E.3
McMahon, S.B.4
-
74
-
-
24644502657
-
From birth to death: The complex lives of eukaryotic mRNAs
-
Moore, M. J. (2005). From birth to death: the complex lives of eukaryotic mRNAs. Science 309, 1514-1518.
-
(2005)
Science
, vol.309
, pp. 1514-1518
-
-
Moore, M.J.1
-
75
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M., and Guarente, L. (2004). Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563.
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
76
-
-
0029009403
-
Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis
-
Nagata, K., Kawase, H., Handa, H., Yano, K., Yamasaki, M., Ishimi, Y., Okuda, A., Kikuchi, A., and Matsumoto, K. (1995). Replication factor encoded by a putative oncogene, set, associated with myeloid leukemogenesis. Proc Natl Acad Sci USA 92, 4279-4283.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4279-4283
-
-
Nagata, K.1
Kawase, H.2
Handa, H.3
Yano, K.4
Yamasaki, M.5
Ishimi, Y.6
Okuda, A.7
Kikuchi, A.8
Matsumoto, K.9
-
77
-
-
0035910515
-
Prothymosin a functions as a cellular oncoprotein by inducing transformation of rodent fibroblasts in vitro
-
Orre, R. S., Cotter, II M. A., Subramanian, C., and Robertson, E. S. (2001). Prothymosin a functions as a cellular oncoprotein by inducing transformation of rodent fibroblasts in vitro. J Biol Chem 276, 1794-1799.
-
(2001)
J Biol Chem
, vol.276
, pp. 1794-1799
-
-
Orre, R.S.1
Cotter, M.A.2
Subramanian, C.3
Robertson, E.S.4
-
78
-
-
38549156700
-
Defining a neuron: Neuronal ELAV proteins
-
Pascale, A., Amadio, M., Quattrone, A. (2008). Defining a neuron: neuronal ELAV proteins. Cell Mol Life Sci 65, 128-140.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 128-140
-
-
Pascale, A.1
Amadio, M.2
Quattrone, A.3
-
79
-
-
0033783289
-
Fifteen years of prothymosin a: Contradictory past and new horizons
-
Pineiro, A., Cordero, O. J., and Nogueira, M. (2000). Fifteen years of prothymosin a: contradictory past and new horizons. Peptides 21, 1433-1446.
-
(2000)
Peptides
, vol.21
, pp. 1433-1446
-
-
Pineiro, A.1
Cordero, O.J.2
Nogueira, M.3
-
80
-
-
34548810305
-
Analysis of Stability and Translation Regulatory RBP Expression Through Binding to Cognate mRNAs
-
Pullmann, R. Jr., Kim, H. H., Abdelmohsen, K., Lal, A., Martindale, J. L., Yang, X., and Gorospe, M. (2007). Analysis of Stability and Translation Regulatory RBP Expression Through Binding to Cognate mRNAs. Mol Cell Biol 27, 6265-6278.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6265-6278
-
-
Pullmann, R.1
Kim, H.H.2
Abdelmohsen, K.3
Lal, A.4
Martindale, J.L.5
Yang, X.6
Gorospe, M.7
-
81
-
-
1642528962
-
Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR
-
Rebane, A., Aab, A., and Steitz, J. A. (2004). Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR. RNA 10, 590-599.
-
(2004)
RNA
, vol.10
, pp. 590-599
-
-
Rebane, A.1
Aab, A.2
Steitz, J.A.3
-
82
-
-
34247345833
-
The apoptosome: Signalling platform of cell death
-
Riedl, S. J. and Salvesen, G. S. (2007). The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 8, 405-413.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 405-413
-
-
Riedl, S.J.1
Salvesen, G.S.2
-
83
-
-
0033573020
-
Caspase-9 and APAF-1 form an active holoenzyme
-
Rodriguez, J. and Lazebnik, Y. (1999). Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev 13, 3179-3184.
-
(1999)
Genes Dev
, vol.13
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
84
-
-
0032079289
-
Overexpression of prothymosin a accelerates proliferation and retards differentiation in HL-60 cells
-
Rodriguez, P., Vinuela, J. E., Alvarez-Fernandez, L., Buceta, M., Vidal, A., Dominguez, F., and Gomez-Marquez, J. (1998). Overexpression of prothymosin a accelerates proliferation and retards differentiation in HL-60 cells. Biochem J 331, 753-761.
-
(1998)
Biochem J
, vol.331
, pp. 753-761
-
-
Rodriguez, P.1
Vinuela, J.E.2
Alvarez-Fernandez, L.3
Buceta, M.4
Vidal, A.5
Dominguez, F.6
Gomez-Marquez, J.7
-
85
-
-
0026018529
-
Prothymosin a antisense oligomers inhibit myeloma cell division
-
Sburlati, A. R., Manrow, R. E, Berger, S. L. (1991). Prothymosin a antisense oligomers inhibit myeloma cell division. Proc Natl Acad Sci USA 88, 253-257
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 253-257
-
-
Sburlati, A.R.1
Manrow, R.E.2
Berger, S.L.3
-
86
-
-
33646087420
-
The apoptosome: Physiological, developmental, and pathological modes of regulation
-
Schafer, Z. T., Kornbluth, S. (2006). The apoptosome: physiological, developmental, and pathological modes of regulation. Dev Cell 10, 549-561.
-
(2006)
Dev Cell
, vol.10
, pp. 549-561
-
-
Schafer, Z.T.1
Kornbluth, S.2
-
87
-
-
33644531879
-
Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells
-
Schafer, Z. T., Parrish, A. B., Wright, K. M., Margolis, S. S., Marks, J. R., Deshmukh, M., and Kornbluth, S. (2006). Enhanced sensitivity to cytochrome c-induced apoptosis mediated by PHAPI in breast cancer cells. Cancer Res. 66, 2210-2218.
-
(2006)
Cancer Res
, vol.66
, pp. 2210-2218
-
-
Schafer, Z.T.1
Parrish, A.B.2
Wright, K.M.3
Margolis, S.S.4
Marks, J.R.5
Deshmukh, M.6
Kornbluth, S.7
-
88
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza, G. L. (2003). Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3, 721-732.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
89
-
-
0043092174
-
The RNA-binding protein HuR regulates the expression of cyclooxygenase-2
-
Sengupta, S., Jang, B. C., Wu, M. T., Paik, J. H., Furneaux, H., Hla, T. (2003). The RNA-binding protein HuR regulates the expression of cyclooxygenase-2. J Biol Chem 278, 25227-25233.
-
(2003)
J Biol Chem
, vol.278
, pp. 25227-25233
-
-
Sengupta, S.1
Jang, B.C.2
Wu, M.T.3
Paik, J.H.4
Furneaux, H.5
Hla, T.6
-
90
-
-
0035846894
-
Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein
-
Seo, S. B., McNamara, P., Heo, S., Turner, A., Lane, W. S., and Chakravarti, D. (2001). Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein. Cell 104, 119-130.
-
(2001)
Cell
, vol.104
, pp. 119-130
-
-
Seo, S.B.1
McNamara, P.2
Heo, S.3
Turner, A.4
Lane, W.S.5
Chakravarti, D.6
-
91
-
-
6044269455
-
Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1a and EGF mRNA
-
Sheflin, L. G., Zou, A. P., and Spaulding, S. W. (2004). Androgens regulate the binding of endogenous HuR to the AU-rich 3'UTRs of HIF-1a and EGF mRNA. Biochem Biophys Res Commun 322, 644-651.
-
(2004)
Biochem Biophys Res Commun
, vol.322
, pp. 644-651
-
-
Sheflin, L.G.1
Zou, A.P.2
Spaulding, S.W.3
-
92
-
-
0028943734
-
Apoptosis in the pathogenesis and treatment of disease
-
Thompson, C. B. (1995). Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
-
(1995)
Science
, vol.267
, pp. 1456-1462
-
-
Thompson, C.B.1
-
93
-
-
0344875497
-
RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation
-
van der Giessen, K., Di-Marco, S., Clair, E., Gallouzi, I. E. (2003). RNAi-mediated HuR depletion leads to the inhibition of muscle cell differentiation. J Biol Chem 278, 47119-47128.
-
(2003)
J Biol Chem
, vol.278
, pp. 47119-47128
-
-
Van Der Giessen, K.1
Di-Marco, S.2
Clair, E.3
Gallouzi, I.E.4
-
94
-
-
0035913903
-
Hsir2 (SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri, H., Dessain, S. K., Ng Eaton, E., Imai, S. I., Frye, R. A., Pandita, T. K., Guarente, L., and Weinberg, R. A. (2001). hSIR2 (SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107, 149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
96
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman, T., Lengauer, C., Kinzler, K. W., and Vogelstein, B. (1996). Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716.
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
97
-
-
0031283291
-
P27Kip1 overexpression causes apoptotic death of mammalian cells
-
Wang, X., Gorospe, M., Huang, Y., and Holbrook, N. J. (1997). p27Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene 15, 2991-2997.
-
(1997)
Oncogene
, vol.15
, pp. 2991-2997
-
-
Wang, X.1
Gorospe, M.2
Huang, Y.3
Holbrook, N.J.4
-
98
-
-
0033959125
-
HuR regulates p21 mRNA stabilization by UV light
-
Wang, W., Furneaux, H., Cheng, H., Caldwell, M. C., Hutter, D., Liu, Y., Holbrook, N., and Gorospe, M. (2000a). HuR regulates p21 mRNA stabilization by UV light. Mol Cell Biol 20, 760-769.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 760-769
-
-
Wang, W.1
Furneaux, H.2
Cheng, H.3
Caldwell, M.C.4
Hutter, D.5
Liu, Y.6
Holbrook, N.7
Gorospe, M.8
-
99
-
-
0034657686
-
HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation
-
Wang, W., Caldwell, M. C., Lin, S., Furneaux, H., and Gorospe, M. (2000b). HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation. EMBO J 19, 2340-2350.
-
(2000)
EMBO J
, vol.19
, pp. 2340-2350
-
-
Wang, W.1
Caldwell, M.C.2
Lin, S.3
Furneaux, H.4
Gorospe, M.5
-
100
-
-
9144266386
-
AMP-activated protein kinase-regulated phosphorylation and acetylation of importin a1: Involvement in the nuclear import of RNA-binding protein HuR
-
Wang, W., Yang, X., Kawai, T., López de Silanes, I., Mazan-Mamczarz, K., Chen, P., Chook, Y. M., Quensel, C., Köhler, M., and Gorospe, M. (2004). AMP-activated protein kinase-regulated phosphorylation and acetylation of importin a1: involvement in the nuclear import of RNA-binding protein HuR. J Biol Chem 279, 48376-48388.
-
(2004)
J Biol Chem
, vol.279
, pp. 48376-48388
-
-
Wang, W.1
Yang, X.2
Kawai, T.3
López De Silanes, I.4
Mazan-Mamczarz, K.5
Chen, P.6
Chook, Y.M.7
Quensel, C.8
Köhler, M.9
Gorospe, M.10
-
101
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
Wenger, R. H., Stiehl, D. P. and Camenisch, G. (2005). Integration of oxygen signaling at the consensus HRE. Sci STKE 306: re12.
-
(2005)
Sci STKE
, vol.306
, pp. re12
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
102
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T.-I., Jones, D. P., and X. Wang. (1997). Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.-I.7
Jones, D.P.8
Wang, X.9
-
103
-
-
49249118307
-
TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma
-
Zhao, J., Chen, J., Lu, B., Dong, L., Wang, H., Bi, C., Wu, G., Guo, H., Wu, M., and Guo, Y. (2008). TIP30 induces apoptosis under oxidative stress through stabilization of p53 messenger RNA in human hepatocellular carcinoma. Cancer Res 68, 4133-4141.
-
(2008)
Cancer Res
, vol.68
, pp. 4133-4141
-
-
Zhao, J.1
Chen, J.2
Lu, B.3
Dong, L.4
Wang, H.5
Bi, C.6
Wu, G.7
Guo, H.8
Wu, M.9
Guo, Y.10
-
104
-
-
33745849149
-
Polyamine depletion increases cytoplas-mic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs
-
Zou, T., Mazan-Mamczarz, K., Rao, J. N., Liu, L., Marasa, B. S., Zhang, A. H., Xiao, L., Pullmann, R., Gorospe, M., and Wang, J. Y. (2006). Polyamine depletion increases cytoplas-mic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs. J Biol Chem 281, 19387-19394.
-
(2006)
J Biol Chem
, vol.281
, pp. 19387-19394
-
-
Zou, T.1
Mazan-Mamczarz, K.2
Rao, J.N.3
Liu, L.4
Marasa, B.S.5
Zhang, A.H.6
Xiao, L.7
Pullmann, R.8
Gorospe, M.9
Wang, J.Y.10
|