-
1
-
-
84896733468
-
Évaluation des risques liés à la présence de mycotoxines dans les chaînes alimentaires humaine et animale.
-
AFSSA
-
AFSSA, 2009. Évaluation des risques liés à la présence de mycotoxines dans les chaînes alimentaires humaine et animale.
-
(2009)
-
-
-
2
-
-
0016685233
-
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test
-
Ames B., McCann J., Yamasaki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test. Mutat. Res. 1975, 31:347-363.
-
(1975)
Mutat. Res.
, vol.31
, pp. 347-363
-
-
Ames, B.1
McCann, J.2
Yamasaki, E.3
-
3
-
-
84862582252
-
The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human
-
Andersson T.B., Kanebratt K.P., Kenna J.G. The HepaRG cell line: a unique in vitro tool for understanding drug metabolism and toxicology in human. Expert Opin. Drug Metab. Toxicol. 2012, 8:909-920.
-
(2012)
Expert Opin. Drug Metab. Toxicol.
, vol.8
, pp. 909-920
-
-
Andersson, T.B.1
Kanebratt, K.P.2
Kenna, J.G.3
-
4
-
-
29944444269
-
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells
-
Aninat C., Piton A., Glaise D., Le Charpentier T., Langouët S., Morel F., Guguen-Guillouzo C., Guillouzo A. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells. Drug Metab. Dispos. 2006, 34:75-83.
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 75-83
-
-
Aninat, C.1
Piton, A.2
Glaise, D.3
Le Charpentier, T.4
Langouët, S.5
Morel, F.6
Guguen-Guillouzo, C.7
Guillouzo, A.8
-
5
-
-
76749107104
-
Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells
-
Anthérieu S., Chesné C., Li R., Camus S., Lahoz A., Picazo L., Turpeinen M., Tolonen A., Uusitalo J., Guguen-Guillouzo C. Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. Drug Metab. Dispos. 2010, 38:516-525.
-
(2010)
Drug Metab. Dispos.
, vol.38
, pp. 516-525
-
-
Anthérieu, S.1
Chesné, C.2
Li, R.3
Camus, S.4
Lahoz, A.5
Picazo, L.6
Turpeinen, M.7
Tolonen, A.8
Uusitalo, J.9
Guguen-Guillouzo, C.10
-
6
-
-
85027942357
-
Optimization of the HepaRG cell model for drug metabolism and toxicity studies
-
Antherieu S., Chesné C., Li R., Guguen-Guillouzo C., Guillouzo A. Optimization of the HepaRG cell model for drug metabolism and toxicity studies. Toxicol. In Vitro 2012, 26:1278-1285.
-
(2012)
Toxicol. In Vitro
, vol.26
, pp. 1278-1285
-
-
Antherieu, S.1
Chesné, C.2
Li, R.3
Guguen-Guillouzo, C.4
Guillouzo, A.5
-
7
-
-
77950351190
-
Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco 2 and HepaRG
-
Bazin E., Mourot A., Humpage A.R., Fessard V. Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco 2 and HepaRG. Environ. Mol. Mutagen. 2010, 51:251-259.
-
(2010)
Environ. Mol. Mutagen.
, vol.51
, pp. 251-259
-
-
Bazin, E.1
Mourot, A.2
Humpage, A.R.3
Fessard, V.4
-
8
-
-
69649097529
-
Pathway of deoxynivalenol-induced apoptosis in human colon carcinoma cells
-
Bensassi F., El Golli-Bennour E., Abid-Essefi S., Bouaziz C., Hajlaoui M.R., Bacha H. Pathway of deoxynivalenol-induced apoptosis in human colon carcinoma cells. Toxicology 2009, 264:104-109.
-
(2009)
Toxicology
, vol.264
, pp. 104-109
-
-
Bensassi, F.1
El Golli-Bennour, E.2
Abid-Essefi, S.3
Bouaziz, C.4
Hajlaoui, M.R.5
Bacha, H.6
-
9
-
-
33747762650
-
Genotoxicity assessment of deoxynivalenol in the Caco-2 cell line model using the Comet assay
-
Bony S., Carcelen M., Olivier L., Devaux A. Genotoxicity assessment of deoxynivalenol in the Caco-2 cell line model using the Comet assay. Toxicol. Lett. 2006, 166:67-76.
-
(2006)
Toxicol. Lett.
, vol.166
, pp. 67-76
-
-
Bony, S.1
Carcelen, M.2
Olivier, L.3
Devaux, A.4
-
10
-
-
84875050640
-
Flow cytometric 96 well microplate based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment
-
Bryce S.M., Avlasevich S.L., Bemis J.C., Tate M., Walmsley R.M., Saad F., Dijck K., Boeck M., Goethem F., Lukamowicz-Rajska M., Elhajouji A., Dertinger S.D. Flow cytometric 96 well microplate based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment. Environ. Mol. Mutagen. 2013, 54:180-194.
-
(2013)
Environ. Mol. Mutagen.
, vol.54
, pp. 180-194
-
-
Bryce, S.M.1
Avlasevich, S.L.2
Bemis, J.C.3
Tate, M.4
Walmsley, R.M.5
Saad, F.6
Dijck, K.7
Boeck, M.8
Goethem, F.9
Lukamowicz-Rajska, M.10
Elhajouji, A.11
Dertinger, S.D.12
-
11
-
-
49649091842
-
Mutagenic potency in Salmonella typhimurium of organic extracts of soil samples originating from urban, suburban, agricultural, forest and natural areas
-
Courty B., Le Curieux F., Belkessam L., Laboudigue A., Marzin D. Mutagenic potency in Salmonella typhimurium of organic extracts of soil samples originating from urban, suburban, agricultural, forest and natural areas. Mutat. Res. 2008, 653:1-5.
-
(2008)
Mutat. Res.
, vol.653
, pp. 1-5
-
-
Courty, B.1
Le Curieux, F.2
Belkessam, L.3
Laboudigue, A.4
Marzin, D.5
-
12
-
-
8844247487
-
Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to Deoxynivalenol (DON) as undesirable substance in animal feed
-
EFSA
-
EFSA, 2004. Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to Deoxynivalenol (DON) as undesirable substance in animal feed. EFSA J. 73, 1-41.
-
(2004)
EFSA J.
, vol.73
, pp. 1-41
-
-
-
13
-
-
85067915354
-
Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment
-
EFSA
-
EFSA, 2011. Scientific opinion on genotoxicity testing strategies applicable to food and feed safety assessment. EFSA J. 9, 1-69.
-
(2011)
EFSA J.
, vol.9
, pp. 1-69
-
-
-
14
-
-
77953806816
-
A strategy to study genotoxicity: application to aquatic toxins, limits and solutions
-
Fessard V., Le Hegarat L. A strategy to study genotoxicity: application to aquatic toxins, limits and solutions. Anal. Bioanal. Chem. 2010, 397:1715-1722.
-
(2010)
Anal. Bioanal. Chem.
, vol.397
, pp. 1715-1722
-
-
Fessard, V.1
Le Hegarat, L.2
-
15
-
-
84856111701
-
Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type
-
Fowler P., Smith K., Young J., Jeffrey L., Kirkland D., Pfuhler S., Carmichael P. Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type. Mutat. Res. 2012, 742:11-25.
-
(2012)
Mutat. Res.
, vol.742
, pp. 11-25
-
-
Fowler, P.1
Smith, K.2
Young, J.3
Jeffrey, L.4
Kirkland, D.5
Pfuhler, S.6
Carmichael, P.7
-
16
-
-
84862331466
-
Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement
-
Fowler P., Smith R., Smith K., Young J., Jeffrey L., Kirkland D., Pfuhler S., Carmichael P. Reduction of misleading ("false") positive results in mammalian cell genotoxicity assays. II. Importance of accurate toxicity measurement. Mutat. Res. 2012, 747:104-117.
-
(2012)
Mutat. Res.
, vol.747
, pp. 104-117
-
-
Fowler, P.1
Smith, R.2
Smith, K.3
Young, J.4
Jeffrey, L.5
Kirkland, D.6
Pfuhler, S.7
Carmichael, P.8
-
17
-
-
84859163249
-
Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins
-
Gerets H., Tilmant K., Gerin B., Chanteux H., Depelchin B., Dhalluin S., Atienzar F. Characterization of primary human hepatocytes, HepG2 cells, and HepaRG cells at the mRNA level and CYP activity in response to inducers and their predictivity for the detection of human hepatotoxins. Cell Biol. Toxicol. 2012, 28:69-87.
-
(2012)
Cell Biol. Toxicol.
, vol.28
, pp. 69-87
-
-
Gerets, H.1
Tilmant, K.2
Gerin, B.3
Chanteux, H.4
Depelchin, B.5
Dhalluin, S.6
Atienzar, F.7
-
18
-
-
84861466287
-
Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage
-
He K., Zhou H.R., Pestka J.J. Targets and intracellular signaling mechanisms for deoxynivalenol-induced ribosomal RNA cleavage. Toxicol. Sci. 2012, 127:382-390.
-
(2012)
Toxicol. Sci.
, vol.127
, pp. 382-390
-
-
He, K.1
Zhou, H.R.2
Pestka, J.J.3
-
19
-
-
79960999090
-
Cytotoxicity measurement in in vitro chromosome aberration test and micronucleus test
-
Honma M. Cytotoxicity measurement in in vitro chromosome aberration test and micronucleus test. Mutat. Res. 2011, 724:86-87.
-
(2011)
Mutat. Res.
, vol.724
, pp. 86-87
-
-
Honma, M.1
-
20
-
-
84860188521
-
An adaptation of the human HepaRG cells to the in vitro micronucleus assay
-
Jossé R., Rogue A., Lorge E., Guillouzo A. An adaptation of the human HepaRG cells to the in vitro micronucleus assay. Mutagenesis 2012, 27:295-304.
-
(2012)
Mutagenesis
, vol.27
, pp. 295-304
-
-
Jossé, R.1
Rogue, A.2
Lorge, E.3
Guillouzo, A.4
-
21
-
-
79951679077
-
A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins
-
Kirkland D., Reeve L., Gatehouse D., Vanparys P. A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins. Mutat. Res. 2011, 721:27-73.
-
(2011)
Mutat. Res.
, vol.721
, pp. 27-73
-
-
Kirkland, D.1
Reeve, L.2
Gatehouse, D.3
Vanparys, P.4
-
22
-
-
0141869980
-
Report from the in vitro micronucleus assay working group
-
Kirsch-Volders M., Sofuni T., Aardema M., Albertini S., Eastmond D., Fenech M., Ishidate M., Kirchner S., Lorge E., Morita T., Norppa H., Surralles J., Vanhauwaert A., Wakata A. Report from the in vitro micronucleus assay working group. Mutat. Res. 2003, 540:153-163.
-
(2003)
Mutat. Res.
, vol.540
, pp. 153-163
-
-
Kirsch-Volders, M.1
Sofuni, T.2
Aardema, M.3
Albertini, S.4
Eastmond, D.5
Fenech, M.6
Ishidate, M.7
Kirchner, S.8
Lorge, E.9
Morita, T.10
Norppa, H.11
Surralles, J.12
Vanhauwaert, A.13
Wakata, A.14
-
23
-
-
0342437504
-
Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes
-
Knasmuller S., Bresgen N., Kassie F., Mersch-Sundermann V., Gelderblom W., Zohrer E., Eckl P.M. Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes. Mutat. Res. 1997, 391:39-48.
-
(1997)
Mutat. Res.
, vol.391
, pp. 39-48
-
-
Knasmuller, S.1
Bresgen, N.2
Kassie, F.3
Mersch-Sundermann, V.4
Gelderblom, W.5
Zohrer, E.6
Eckl, P.M.7
-
24
-
-
78149369707
-
Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays
-
Le Hegarat L., Dumont J., Josse R., Huet S., Lanceleur R., Mourot A., Poul J.M., Guguen-Guillouzo C., Guillouzo A., Fessard V. Assessment of the genotoxic potential of indirect chemical mutagens in HepaRG cells by the comet and the cytokinesis-block micronucleus assays. Mutagenesis 2010, 25:555-560.
-
(2010)
Mutagenesis
, vol.25
, pp. 555-560
-
-
Le Hegarat, L.1
Dumont, J.2
Josse, R.3
Huet, S.4
Lanceleur, R.5
Mourot, A.6
Poul, J.M.7
Guguen-Guillouzo, C.8
Guillouzo, A.9
Fessard, V.10
-
25
-
-
22344452122
-
Estimated dietary exposure to principal food mycotoxins from the first French Total Diet Study
-
Leblanc J.C., Tard A., Volatier J.L., Verger P. Estimated dietary exposure to principal food mycotoxins from the first French Total Diet Study. Food Addit. Contam. 2005, 22:652-672.
-
(2005)
Food Addit. Contam.
, vol.22
, pp. 652-672
-
-
Leblanc, J.C.1
Tard, A.2
Volatier, J.L.3
Verger, P.4
-
26
-
-
77958084075
-
Comparison of different cytotoxicity measurements for the in vitro micronucleus assay using L5178Y and TK6 cells in support of OECD draft Test Guideline 487
-
Lorge E. Comparison of different cytotoxicity measurements for the in vitro micronucleus assay using L5178Y and TK6 cells in support of OECD draft Test Guideline 487. Mutat. Res. 2010, 702:199-207.
-
(2010)
Mutat. Res.
, vol.702
, pp. 199-207
-
-
Lorge, E.1
-
27
-
-
50349083414
-
Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. I. Theoretical aspects
-
Lorge E., Hayashi M., Albertini S., Kirkland D. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. I. Theoretical aspects. Mutat. Res. 2008, 655:1-3.
-
(2008)
Mutat. Res.
, vol.655
, pp. 1-3
-
-
Lorge, E.1
Hayashi, M.2
Albertini, S.3
Kirkland, D.4
-
28
-
-
84862825477
-
A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells
-
Ma Y., Zhang A., Shi Z., He C., Ding J., Wang X., Ma J., Zhang H. A mitochondria-mediated apoptotic pathway induced by deoxynivalenol in human colon cancer cells. Toxicol. In Vitro 2012, 26:414-420.
-
(2012)
Toxicol. In Vitro
, vol.26
, pp. 414-420
-
-
Ma, Y.1
Zhang, A.2
Shi, Z.3
He, C.4
Ding, J.5
Wang, X.6
Ma, J.7
Zhang, H.8
-
29
-
-
0003062746
-
Analysis of data from microbial colony assays.
-
In: Kirkland, D. (Ed.), Statistical Evaluation of Mutagenicity test Data - UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Report Part III. Cambridge, New-York
-
Mahon, G.A.T., Middleton, B., Robinson, W.D., Green, M.H.L., Mitchell, I., Tweats, D.J., 1989. Analysis of data from microbial colony assays. In: Kirkland, D. (Ed.), Statistical Evaluation of Mutagenicity test Data - UKEMS Sub-Committee on Guidelines for Mutagenicity Testing, Report Part III. Cambridge, New-York, pp. 26-65.
-
(1989)
, pp. 26-65
-
-
Mahon, G.A.T.1
Middleton, B.2
Robinson, W.D.3
Green, M.H.L.4
Mitchell, I.5
Tweats, D.J.6
-
30
-
-
0020533372
-
Revised methods for the Salmonella mutagenicity test
-
Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutat. Res. 1983, 113:173-215.
-
(1983)
Mutat. Res.
, vol.113
, pp. 173-215
-
-
Maron, D.M.1
Ames, B.N.2
-
31
-
-
77958108582
-
Cytosine arabinoside, vinblastine, diethylstilboestrol and 2-aminoanthracene tested in the in vitro human TK6 cell line micronucleus test (MNvit) at Institut Pasteur de Lille in support of OECD draft test guideline 487
-
Nesslany F., Marzin D. Cytosine arabinoside, vinblastine, diethylstilboestrol and 2-aminoanthracene tested in the in vitro human TK6 cell line micronucleus test (MNvit) at Institut Pasteur de Lille in support of OECD draft test guideline 487. Mutat. Res. 2010, 702:212-218.
-
(2010)
Mutat. Res.
, vol.702
, pp. 212-218
-
-
Nesslany, F.1
Marzin, D.2
-
32
-
-
68349133588
-
Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay
-
Nesslany F., Simar-Meintières S., Ficheux H., Marzin D. Aloe-emodin-induced DNA fragmentation in the mouse in vivo comet assay. Mutat. Res. 2009, 678:13-19.
-
(2009)
Mutat. Res.
, vol.678
, pp. 13-19
-
-
Nesslany, F.1
Simar-Meintières, S.2
Ficheux, H.3
Marzin, D.4
-
33
-
-
84868538327
-
A critique of methods to measure cytotoxicity in mammalian cell genotoxicity assays
-
O'Donovan M. A critique of methods to measure cytotoxicity in mammalian cell genotoxicity assays. Mutagenesis 2012, 27:615-621.
-
(2012)
Mutagenesis
, vol.27
, pp. 615-621
-
-
O'Donovan, M.1
-
34
-
-
84896731296
-
-
OECD, Test No. 471: Bacterial Reverse Mutation Test. OECD Publishing.
-
OECD, 1997. Test No. 471: Bacterial Reverse Mutation Test. OECD Publishing.
-
(1997)
-
-
-
35
-
-
84896713055
-
-
OECD, Test No. 487. In Vitro Mammalian Cell Micronucleus Test. OECD Publishing.
-
OECD, 2010. Test No. 487. In Vitro Mammalian Cell Micronucleus Test. OECD Publishing.
-
(2010)
-
-
-
36
-
-
79959720615
-
In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop
-
Pfuhler S., Fellows M., van Benthem J., Corvi R., Curren R., Dearfield K., Fowler P., Frotschl R., Elhajouji A., Le Hegarat L., Kasamatsu T., Kojima H., Ouedraogo G., Scott A., Speit G. In vitro genotoxicity test approaches with better predictivity: summary of an IWGT workshop. Mutat. Res. 2011, 723:101-107.
-
(2011)
Mutat. Res.
, vol.723
, pp. 101-107
-
-
Pfuhler, S.1
Fellows, M.2
van Benthem, J.3
Corvi, R.4
Curren, R.5
Dearfield, K.6
Fowler, P.7
Frotschl, R.8
Elhajouji, A.9
Le Hegarat, L.10
Kasamatsu, T.11
Kojima, H.12
Ouedraogo, G.13
Scott, A.14
Speit, G.15
-
37
-
-
10044297379
-
Baseline levels of chromosome instability in the human lymphoblastoid cell TK6
-
Schwartz J.L., Jordan R., Evans H.H., Lenarczyk M., Liber H.L. Baseline levels of chromosome instability in the human lymphoblastoid cell TK6. Mutagenesis 2004, 19:477-482.
-
(2004)
Mutagenesis
, vol.19
, pp. 477-482
-
-
Schwartz, J.L.1
Jordan, R.2
Evans, H.H.3
Lenarczyk, M.4
Liber, H.L.5
-
38
-
-
77249135763
-
Coupling cytotoxicity biomarkers with DNA damage assessment in TK6 human lymphoblast cells
-
Shi J., Springer S., Escobar P. Coupling cytotoxicity biomarkers with DNA damage assessment in TK6 human lymphoblast cells. Mutat. Res. 2010, 696:167-178.
-
(2010)
Mutat. Res.
, vol.696
, pp. 167-178
-
-
Shi, J.1
Springer, S.2
Escobar, P.3
-
39
-
-
84869132263
-
Dietary exposure to mycotoxins and health risk assessment in the second French total diet study
-
Sirot V., Fremy J.-M., Leblanc J.-C. Dietary exposure to mycotoxins and health risk assessment in the second French total diet study. Food Chem. Toxicol. 2013, 52:1-11.
-
(2013)
Food Chem. Toxicol.
, vol.52
, pp. 1-11
-
-
Sirot, V.1
Fremy, J.-M.2
Leblanc, J.-C.3
-
40
-
-
0017880759
-
Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins
-
Wehner F.C., Marasas W.F., Thiel P.G. Lack of mutagenicity to Salmonella typhimurium of some Fusarium mycotoxins. Appl. Environ. Microbiol. 1978, 35:659-662.
-
(1978)
Appl. Environ. Microbiol.
, vol.35
, pp. 659-662
-
-
Wehner, F.C.1
Marasas, W.F.2
Thiel, P.G.3
-
41
-
-
67650257177
-
The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells.
-
Zhang, X., Jiang, L., Geng, C., Cao, J., Zhong, L., 2009. The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells. Toxicon: Official J. Int. Soc. Toxinol. 54, 513-518.
-
(2009)
Toxicon: Official J. Int. Soc. Toxinol.
, vol.54
, pp. 513-518
-
-
Zhang, X.1
Jiang, L.2
Geng, C.3
Cao, J.4
Zhong, L.5
|