Reduction of misleading (" false") positive results in mammalian cell genotoxicity assays. I. Choice of cell type

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 742, Issue 1-2, 2012, Pages 11-25

  Fowler, Paul ^a,b   Smith, Katie ^b   Young, Jamie ^b   Jeffrey, Laura ^b   Kirkland, David ^c   Pfuhler, Stefan ^d   Carmichael, Paul ^a  

^a UNILEVER RESEARCH   (United Kingdom)

^b Department of Genetic and Molecular Toxicology   (United Kingdom)

^c Kirkland Consulting   (United Kingdom)

^d PROCTER AND GAMBLE COMPANY   (United States)

Author keywords

Genotoxicity; Mammalian cells; Misleading positive results

Indexed keywords

2,4 DICHLOROPHENOL; 4 NITROPHENOL; ACRYLIC ACID ETHYL ESTER; ANTHRANILIC ACID; BENZYL ALCOHOL; CURCUMIN; ETHIONAMIDE; EUGENOL; GALLIC ACID PROPYL ESTER; ISOBUTYRALDEHYDE; MENTHOL; PHTHALIC ANHYDRIDE; PROTEIN P53; RESORCINOL; SACCHARIN SODIUM; SULFAFURAZOLE; TERT BUTYLHYDROQUINONE; UREA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FALSE POSITIVE RESULT; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOBLASTOID CELL LINE; MAMMAL CELL; MICRONUCLEUS; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

ANIMALS; CARCINOGENS; CELL LINE; DNA DAMAGE; FALSE POSITIVE REACTIONS; HUMANS; LYMPHOCYTES; MICE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTAGENS;

MAMMALIA; RODENTIA;

EID: 84856111701     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2011.10.014     Document Type: Article

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