Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. I. Theoretical aspects.

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 655, Issue 1-2, 2008, Pages 1-3

  Lorge, E ^a   Hayashi, M ^b   Albertini, S ^c   Kirkland, D ^d  

^a INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d UK   (United Kingdom)

Author keywords

Cytotoxicity; Genotoxicity; In vitro micronucleus test; Increased cell count; Mouse lymphoma cells; Population doubling; Relative increase in cell count

Indexed keywords

CYTOCHALASIN B;

ARTICLE; CELL COUNT; CELL CULTURE; CELL POPULATION; CYTOKINESIS BLOCK PROLIFERATION INDEX; CYTOTOXICITY; CYTOTOXICITY TEST; DYNAMICS; IN VITRO STUDY; MICRONUCLEUS TEST; PRIORITY JOURNAL; REPLICATION INDEX; ANIMAL; CELL PROLIFERATION; METABOLISM; METHODOLOGY; MOUSE; STANDARD; THEORETICAL MODEL; TUMOR CELL LINE;

ANIMALS; CELL COUNT; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHALASIN B; MICE; MICRONUCLEUS TESTS; MODELS, THEORETICAL;

EID: 50349083414     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.06.003     Document Type: Article

References (5)

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5. Fellows M.D., O'Donovan M.R., Lorge E., Kirkland D. Comparison of different methods for an accurate assessment of cytotoxicity in the in vitro micronucleus test. II. Practical aspects with toxic agents. Mutat. Res. 2008, 655:4-21.