메뉴 건너뛰기




Volumn 7, Issue 1, 2014, Pages 1-17

The immunoinhibitory B7-H1 molecule as a potential target in cancer: Killing many birds with one stone

Author keywords

B7 H1; Cancer prognosis; CD 274; Immune escape; PD L1; Targeted therapy

Indexed keywords

BMS 936559; CISPLATIN; CYTARABINE; DAUNORUBICIN; DENDRITIC CELL VACCINE; DOCETAXEL; DOXORUBICIN; GAMMA INTERFERON; HONOKIOL; MELOXICAM; MONOCLONAL ANTIBODY; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NIMESULIDE; PEPTIDE DERIVATIVE; PROGRAMMED DEATH 1 LIGAND 1; SINOMENINE; SMALL INTERFERING RNA; TRIPTOLIDE; UNCLASSIFIED DRUG;

EID: 84896713991     PISSN: 16583876     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hemonc.2013.09.005     Document Type: Review
Times cited : (89)

References (194)
  • 2
    • 84877330702 scopus 로고    scopus 로고
    • Cancer immunoediting: Antigens, mechanisms, and implications to cancer immunotherapy
    • M.D. Vesely, and R.D. Schreiber Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy Ann N Y Acad Sci 1284 2013 1 5
    • (2013) Ann N y Acad Sci , vol.1284 , pp. 1-5
    • Vesely, M.D.1    Schreiber, R.D.2
  • 3
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Y. Iwai, M. Ishida, Y. Tanaka, T. Okazaki, T. Honjo, and N. Minato Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade Proc Natl Acad Sci U S A 99 19 2002 12293 12297
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.19 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 4
    • 33646367200 scopus 로고    scopus 로고
    • The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: Correlation with important high-risk prognostic factors
    • H. Ghebeh, S. Mohammed, A. Al-Omair, A. Qattan, C. Lehe, and G. Al-Qudaihi et al. The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors Neoplasia 8 3 2006 190 198
    • (2006) Neoplasia , vol.8 , Issue.3 , pp. 190-198
    • Ghebeh, H.1    Mohammed, S.2    Al-Omair, A.3    Qattan, A.4    Lehe, C.5    Al-Qudaihi, G.6
  • 5
    • 34547098581 scopus 로고    scopus 로고
    • Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells
    • H. Ghebeh, A. Tulbah, S. Mohammed, N. Elkum, S.M. Bin Amer, and T. Al-Tweigeri et al. Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells Int J Cancer 121 4 2007 751 758
    • (2007) Int J Cancer , vol.121 , Issue.4 , pp. 751-758
    • Ghebeh, H.1    Tulbah, A.2    Mohammed, S.3    Elkum, N.4    Bin Amer, S.M.5    Al-Tweigeri, T.6
  • 6
    • 42049111164 scopus 로고    scopus 로고
    • FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy
    • H. Ghebeh, E. Barhoush, A. Tulbah, N. Elkum, T. Al-Tweigeri, and S. Dermime FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: implication for immunotherapy BMC Cancer 23 8 2008 57
    • (2008) BMC Cancer , vol.23 , Issue.8 , pp. 57
    • Ghebeh, H.1    Barhoush, E.2    Tulbah, A.3    Elkum, N.4    Al-Tweigeri, T.5    Dermime, S.6
  • 7
    • 78650899557 scopus 로고    scopus 로고
    • Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: Role of B7-H1 as an anti-apoptotic molecule
    • H. Ghebeh, C. Lehe, E. Barhoush, K. Al-Romaih, A. Tulbah, and M. Al-Alwan et al. Doxorubicin downregulates cell surface B7-H1 expression and upregulates its nuclear expression in breast cancer cells: role of B7-H1 as an anti-apoptotic molecule Breast Cancer Res 12 4 2010 R48
    • (2010) Breast Cancer Res , vol.12 , Issue.4 , pp. 48
    • Ghebeh, H.1    Lehe, C.2    Barhoush, E.3    Al-Romaih, K.4    Tulbah, A.5    Al-Alwan, M.6
  • 8
    • 0037307930 scopus 로고    scopus 로고
    • Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production
    • J.A. Brown, D.M. Dorfman, F.R. Ma, E.L. Sullivan, O. Munoz, and C.R. Wood et al. Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production J Immunol 170 3 2003 1257 1266
    • (2003) J Immunol , vol.170 , Issue.3 , pp. 1257-1266
    • Brown, J.A.1    Dorfman, D.M.2    Ma, F.R.3    Sullivan, E.L.4    Munoz, O.5    Wood, C.R.6
  • 9
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • H. Dong, S.E. Strome, D.R. Salomao, H. Tamura, F. Hirano, and D.B. Flies et al. Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion Nat Med 8 8 2002 793 800
    • (2002) Nat Med , vol.8 , Issue.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3    Tamura, H.4    Hirano, F.5    Flies, D.B.6
  • 10
    • 0038273853 scopus 로고    scopus 로고
    • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
    • T.J. Curiel, S. Wei, H. Dong, X. Alvarez, P. Cheng, and P. Mottram et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity Nat Med 9 5 2003 562 567
    • (2003) Nat Med , vol.9 , Issue.5 , pp. 562-567
    • Curiel, T.J.1    Wei, S.2    Dong, H.3    Alvarez, X.4    Cheng, P.5    Mottram, P.6
  • 11
    • 33847611968 scopus 로고    scopus 로고
    • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer
    • J. Hamanishi, M. Mandai, M. Iwasaki, T. Okazaki, Y. Tanaka, and K. Yamaguchi et al. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer Proc Natl Acad Sci U S A 104 9 2007 3360 3365
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.9 , pp. 3360-3365
    • Hamanishi, J.1    Mandai, M.2    Iwasaki, M.3    Okazaki, T.4    Tanaka, Y.5    Yamaguchi, K.6
  • 12
    • 70350247885 scopus 로고    scopus 로고
    • Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma
    • R. Karim, E.S. Jordanova, S.J. Piersma, G.G. Kenter, L. Chen, and J.M. Boer et al. Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma Clin Cancer Res 15 20 2009 6341 6347
    • (2009) Clin Cancer Res , vol.15 , Issue.20 , pp. 6341-6347
    • Karim, R.1    Jordanova, E.S.2    Piersma, S.J.3    Kenter, G.G.4    Chen, L.5    Boer, J.M.6
  • 13
    • 82255179501 scopus 로고    scopus 로고
    • Relationship between the expressions of PD-L1 and tumor-infiltrating lymphocytes in oral squamous cell carcinoma
    • Y.A. Cho, H.J. Yoon, J.I. Lee, S.P. Hong, and S.D. Hong Relationship between the expressions of PD-L1 and tumor-infiltrating lymphocytes in oral squamous cell carcinoma Oral Oncol 47 12 2011 1148 1153
    • (2011) Oral Oncol , vol.47 , Issue.12 , pp. 1148-1153
    • Cho, Y.A.1    Yoon, H.J.2    Lee, J.I.3    Hong, S.P.4    Hong, S.D.5
  • 14
    • 79959765108 scopus 로고    scopus 로고
    • Enhanced programmed death 1 (PD-1) and PD-1 ligand (PD-L1) expression in patients with actinic cheilitis and oral squamous cell carcinoma
    • T.S. Malaspina, T.H. Gasparoto, M.R. Costa, E.F. de Melo, M.R. Ikoma Jr., and J.H. Damante et al. Enhanced programmed death 1 (PD-1) and PD-1 ligand (PD-L1) expression in patients with actinic cheilitis and oral squamous cell carcinoma Cancer Immunol Immunother 60 7 2011 965 974
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.7 , pp. 965-974
    • Malaspina, T.S.1    Gasparoto, T.H.2    Costa, M.R.3    De Melo, E.F.4    Ikoma, Jr.M.R.5    Damante, J.H.6
  • 15
    • 32644484710 scopus 로고    scopus 로고
    • Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma
    • F. Tsushima, K. Tanaka, N. Otsuki, P. Youngnak, H. Iwai, and K. Omura et al. Predominant expression of B7-H1 and its immunoregulatory roles in oral squamous cell carcinoma Oral Oncol 42 3 2006 268 274
    • (2006) Oral Oncol , vol.42 , Issue.3 , pp. 268-274
    • Tsushima, F.1    Tanaka, K.2    Otsuki, N.3    Youngnak, P.4    Iwai, H.5    Omura, K.6
  • 16
    • 84875475811 scopus 로고    scopus 로고
    • Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma
    • S. Lyford-Pike, S. Peng, G.D. Young, J.M. Taube, W.H. Westra, and B. Akpeng et al. Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma Cancer Res 73 6 2013 1733 1741
    • (2013) Cancer Res , vol.73 , Issue.6 , pp. 1733-1741
    • Lyford-Pike, S.1    Peng, S.2    Young, G.D.3    Taube, J.M.4    Westra, W.H.5    Akpeng, B.6
  • 17
    • 0141953992 scopus 로고    scopus 로고
    • B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma
    • S.E. Strome, H. Dong, H. Tamura, S.G. Voss, D.B. Flies, and K. Tamada et al. B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma Cancer Res 63 19 2003 6501 6505
    • (2003) Cancer Res , vol.63 , Issue.19 , pp. 6501-6505
    • Strome, S.E.1    Dong, H.2    Tamura, H.3    Voss, S.G.4    Flies, D.B.5    Tamada, K.6
  • 18
    • 77955665451 scopus 로고    scopus 로고
    • Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions
    • T. Avril, S. Saikali, E. Vauleon, A. Jary, A. Hamlat, and M. De Tayrac et al. Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions J Neuroimmunol 225 1-2 2010 22 33
    • (2010) J Neuroimmunol , vol.225 , Issue.12 , pp. 22-33
    • Avril, T.1    Saikali, S.2    Vauleon, E.3    Jary, A.4    Hamlat, A.5    De Tayrac, M.6
  • 19
    • 68949085209 scopus 로고    scopus 로고
    • Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors
    • J.F. Jacobs, A.J. Idema, K.F. Bol, S. Nierkens, O.M. Grauer, and P. Wesseling et al. Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors Neuro Oncol 11 4 2009 394 402
    • (2009) Neuro Oncol , vol.11 , Issue.4 , pp. 394-402
    • Jacobs, J.F.1    Idema, A.J.2    Bol, K.F.3    Nierkens, S.4    Grauer, O.M.5    Wesseling, P.6
  • 20
  • 21
    • 0242442492 scopus 로고    scopus 로고
    • Expression of the B7-related molecule B7-H1 by glioma cells: A potential mechanism of immune paralysis
    • S. Wintterle, B. Schreiner, M. Mitsdoerffer, D. Schneider, L. Chen, and R. Meyermann et al. Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis Cancer Res 63 21 2003 7462 7467
    • (2003) Cancer Res , vol.63 , Issue.21 , pp. 7462-7467
    • Wintterle, S.1    Schreiner, B.2    Mitsdoerffer, M.3    Schneider, D.4    Chen, L.5    Meyermann, R.6
  • 22
    • 73249125835 scopus 로고    scopus 로고
    • B7-H1 is correlated with malignancy-grade gliomas but is not expressed exclusively on tumor stem-like cells
    • Y. Yao, R. Tao, X. Wang, Y. Wang, Y. Mao, and L.F. Zhou B7-H1 is correlated with malignancy-grade gliomas but is not expressed exclusively on tumor stem-like cells Neuro Oncol 11 6 2009 757 766
    • (2009) Neuro Oncol , vol.11 , Issue.6 , pp. 757-766
    • Yao, Y.1    Tao, R.2    Wang, X.3    Wang, Y.4    Mao, Y.5    Zhou, L.F.6
  • 24
    • 4243096258 scopus 로고    scopus 로고
    • B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression
    • J. Konishi, K. Yamazaki, M. Azuma, I. Kinoshita, H. Dosaka-Akita, and M. Nishimura B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression Clin Cancer Res 10 15 2004 5094 5100
    • (2004) Clin Cancer Res , vol.10 , Issue.15 , pp. 5094-5100
    • Konishi, J.1    Yamazaki, K.2    Azuma, M.3    Kinoshita, I.4    Dosaka-Akita, H.5    Nishimura, M.6
  • 25
    • 80052476869 scopus 로고    scopus 로고
    • High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation
    • C.Y. Mu, J.A. Huang, Y. Chen, C. Chen, and X.G. Zhang High expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation Med Oncol 28 3 2011 682 688
    • (2011) Med Oncol , vol.28 , Issue.3 , pp. 682-688
    • Mu, C.Y.1    Huang, J.A.2    Chen, Y.3    Chen, C.4    Zhang, X.G.5
  • 26
    • 77957551174 scopus 로고    scopus 로고
    • Increase of programmed death-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma
    • M.C. Hsu, J.R. Hsiao, K.C. Chang, Y.H. Wu, I.J. Su, and Y.T. Jin et al. Increase of programmed death-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma Mod Pathol 23 10 2010 1393 1403
    • (2010) Mod Pathol , vol.23 , Issue.10 , pp. 1393-1403
    • Hsu, M.C.1    Hsiao, J.R.2    Chang, K.C.3    Wu, Y.H.4    Su, I.J.5    Jin, Y.T.6
  • 27
    • 79958853436 scopus 로고    scopus 로고
    • The clinical significance of the expression of costimulatory molecule PD-L1 in nasopharyngeal carcinoma
    • [in Chinese]
    • F. Zhang, Z. Liu, Y. Cui, G. Wang, and P. Cao The clinical significance of the expression of costimulatory molecule PD-L1 in nasopharyngeal carcinoma Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 22 9 2008 408 410 [in Chinese]
    • (2008) Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi , vol.22 , Issue.9 , pp. 408-410
    • Zhang, F.1    Liu, Z.2    Cui, Y.3    Wang, G.4    Cao, P.5
  • 28
    • 79953113978 scopus 로고    scopus 로고
    • Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma
    • M. Loos, R. Langer, T. Schuster, R. Gertler, A. Walch, and S. Rauser et al. Clinical significance of the costimulatory molecule B7-H1 in Barrett carcinoma Ann Thorac Surg 91 4 2011 1025 1031
    • (2011) Ann Thorac Surg , vol.91 , Issue.4 , pp. 1025-1031
    • Loos, M.1    Langer, R.2    Schuster, T.3    Gertler, R.4    Walch, A.5    Rauser, S.6
  • 29
    • 20244384862 scopus 로고    scopus 로고
    • Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
    • Y. Ohigashi, M. Sho, Y. Yamada, Y. Tsurui, K. Hamada, and N. Ikeda et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer Clin Cancer Res 11 8 2005 2947 2953
    • (2005) Clin Cancer Res , vol.11 , Issue.8 , pp. 2947-2953
    • Ohigashi, Y.1    Sho, M.2    Yamada, Y.3    Tsurui, Y.4    Hamada, K.5    Ikeda, N.6
  • 30
    • 33745491116 scopus 로고    scopus 로고
    • Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance
    • C. Wu, Y. Zhu, J. Jiang, J. Zhao, X.G. Zhang, and N. Xu Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance Acta Histochem 108 1 2006 19 24
    • (2006) Acta Histochem , vol.108 , Issue.1 , pp. 19-24
    • Wu, C.1    Zhu, Y.2    Jiang, J.3    Zhao, J.4    Zhang, X.G.5    Xu, N.6
  • 31
    • 84856747778 scopus 로고    scopus 로고
    • Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas
    • J. Chen, G. Li, H. Meng, Y. Fan, Y. Song, and S. Wang et al. Upregulation of B7-H1 expression is associated with macrophage infiltration in hepatocellular carcinomas Cancer Immunol Immunother 61 1 2012 101 108
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.1 , pp. 101-108
    • Chen, J.1    Li, G.2    Meng, H.3    Fan, Y.4    Song, Y.5    Wang, S.6
  • 32
    • 61549122071 scopus 로고    scopus 로고
    • Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma
    • Q. Gao, X.Y. Wang, S.J. Qiu, I. Yamato, M. Sho, and Y. Nakajima et al. Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma Clin Cancer Res 15 3 2009 971 979
    • (2009) Clin Cancer Res , vol.15 , Issue.3 , pp. 971-979
    • Gao, Q.1    Wang, X.Y.2    Qiu, S.J.3    Yamato, I.4    Sho, M.5    Nakajima, Y.6
  • 33
    • 80051604040 scopus 로고    scopus 로고
    • B7-H1 up-regulated expression in human hepatocellular carcinoma tissue: Correlation with tumor interleukin-10 levels
    • L. Geng, J. Deng, G. Jiang, P. Song, Z. Wang, and Z. Jiang et al. B7-H1 up-regulated expression in human hepatocellular carcinoma tissue: correlation with tumor interleukin-10 levels Hepatogastroenterology 58 107-108 2011 960 964
    • (2011) Hepatogastroenterology , vol.58 , Issue.107-108 , pp. 960-964
    • Geng, L.1    Deng, J.2    Jiang, G.3    Song, P.4    Wang, Z.5    Jiang, Z.6
  • 34
    • 80051961168 scopus 로고    scopus 로고
    • Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    • B.J. Wang, J.J. Bao, J.Z. Wang, Y. Wang, M. Jiang, and M.Y. Xing et al. Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma World J Gastroenterol 17 28 2011 3322 3329
    • (2011) World J Gastroenterol , vol.17 , Issue.28 , pp. 3322-3329
    • Wang, B.J.1    Bao, J.J.2    Wang, J.Z.3    Wang, Y.4    Jiang, M.5    Xing, M.Y.6
  • 35
    • 70350234729 scopus 로고    scopus 로고
    • Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions
    • K. Wu, I. Kryczek, L. Chen, W. Zou, and T.H. Welling Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions Cancer Res 69 20 2009 8067 8075
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8067-8075
    • Wu, K.1    Kryczek, I.2    Chen, L.3    Zou, W.4    Welling, T.H.5
  • 36
    • 70350335367 scopus 로고    scopus 로고
    • Interaction of B7-H1 on intrahepatic cholangiocarcinoma cells with PD-1 on tumor-infiltrating T cells as a mechanism of immune evasion
    • Y. Ye, L. Zhou, X. Xie, G. Jiang, H. Xie, and S. Zheng Interaction of B7-H1 on intrahepatic cholangiocarcinoma cells with PD-1 on tumor-infiltrating T cells as a mechanism of immune evasion J Surg Oncol 100 6 2009 500 504
    • (2009) J Surg Oncol , vol.100 , Issue.6 , pp. 500-504
    • Ye, Y.1    Zhou, L.2    Xie, X.3    Jiang, G.4    Xie, H.5    Zheng, S.6
  • 37
    • 84863237628 scopus 로고    scopus 로고
    • B7-H1 expression is associated with expansion of regulatory T cells in colorectal carcinoma
    • D. Hua, J. Sun, Y. Mao, L.J. Chen, Y.Y. Wu, and X.G. Zhang B7-H1 expression is associated with expansion of regulatory T cells in colorectal carcinoma World J Gastroenterol 18 9 2012 971 978
    • (2012) World J Gastroenterol , vol.18 , Issue.9 , pp. 971-978
    • Hua, D.1    Sun, J.2    Mao, Y.3    Chen, L.J.4    Wu, Y.Y.5    Zhang, X.G.6
  • 39
    • 85044708346 scopus 로고    scopus 로고
    • Expression of B7-H1 protein in human pancreatic carcinoma tissues and its clinical significance
    • [in Chinese]
    • X.L. Chen, S.X. Yuan, C. Chen, Y.X. Mao, G. Xu, and X.Y. Wang Expression of B7-H1 protein in human pancreatic carcinoma tissues and its clinical significance Ai Zheng 28 12 2009 1328 1332 [in Chinese]
    • (2009) Ai Zheng , vol.28 , Issue.12 , pp. 1328-1332
    • Chen, X.L.1    Yuan, S.X.2    Chen, C.3    Mao, Y.X.4    Xu, G.5    Wang, X.Y.6
  • 40
    • 49649093382 scopus 로고    scopus 로고
    • B7-H1 up-regulated expression in human pancreatic carcinoma tissue associates with tumor progression
    • L. Geng, D. Huang, J. Liu, Y. Qian, J. Deng, and D. Li et al. B7-H1 up-regulated expression in human pancreatic carcinoma tissue associates with tumor progression J Cancer Res Clin Oncol 134 9 2008 1021 1027
    • (2008) J Cancer Res Clin Oncol , vol.134 , Issue.9 , pp. 1021-1027
    • Geng, L.1    Huang, D.2    Liu, J.3    Qian, Y.4    Deng, J.5    Li, D.6
  • 42
    • 48149092796 scopus 로고    scopus 로고
    • Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer
    • M. Loos, N.A. Giese, J. Kleeff, T. Giese, M.M. Gaida, and F. Bergmann et al. Clinical significance and regulation of the costimulatory molecule B7-H1 in pancreatic cancer Cancer Lett 268 1 2008 98 109
    • (2008) Cancer Lett , vol.268 , Issue.1 , pp. 98-109
    • Loos, M.1    Giese, N.A.2    Kleeff, J.3    Giese, T.4    Gaida, M.M.5    Bergmann, F.6
  • 43
    • 34247532726 scopus 로고    scopus 로고
    • Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
    • T. Nomi, M. Sho, T. Akahori, K. Hamada, A. Kubo, and H. Kanehiro et al. Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer Clin Cancer Res 13 7 2007 2151 2157
    • (2007) Clin Cancer Res , vol.13 , Issue.7 , pp. 2151-2157
    • Nomi, T.1    Sho, M.2    Akahori, T.3    Hamada, K.4    Kubo, A.5    Kanehiro, H.6
  • 44
    • 77954716038 scopus 로고    scopus 로고
    • Clinical significance of B7-H1 and B7-1 expressions in pancreatic carcinoma
    • L. Wang, Q. Ma, X. Chen, K. Guo, J. Li, and M. Zhang Clinical significance of B7-H1 and B7-1 expressions in pancreatic carcinoma World J Surg 34 5 2010 1059 1065
    • (2010) World J Surg , vol.34 , Issue.5 , pp. 1059-1065
    • Wang, L.1    Ma, Q.2    Chen, X.3    Guo, K.4    Li, J.5    Zhang, M.6
  • 45
    • 33745197352 scopus 로고    scopus 로고
    • Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro
    • C. Blank, J. Kuball, S. Voelkl, H. Wiendl, B. Becker, and B. Walter et al. Blockade of PD-L1 (B7-H1) augments human tumor-specific T cell responses in vitro Int J Cancer 119 2 2006 317 327
    • (2006) Int J Cancer , vol.119 , Issue.2 , pp. 317-327
    • Blank, C.1    Kuball, J.2    Voelkl, S.3    Wiendl, H.4    Becker, B.5    Walter, B.6
  • 46
    • 34250209885 scopus 로고    scopus 로고
    • Survivin and B7-H1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma
    • A.E. Krambeck, H. Dong, R.H. Thompson, S.M. Kuntz, C.M. Lohse, and B.C. Leibovich et al. Survivin and B7-H1 are collaborative predictors of survival and represent potential therapeutic targets for patients with renal cell carcinoma Clin Cancer Res 13 6 2007 1749 1756
    • (2007) Clin Cancer Res , vol.13 , Issue.6 , pp. 1749-1756
    • Krambeck, A.E.1    Dong, H.2    Thompson, R.H.3    Kuntz, S.M.4    Lohse, C.M.5    Leibovich, B.C.6
  • 47
    • 10344220548 scopus 로고    scopus 로고
    • Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
    • R.H. Thompson, M.D. Gillett, J.C. Cheville, C.M. Lohse, H. Dong, and W.S. Webster et al. Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target Proc Natl Acad Sci U S A 101 49 2004 17174 17179
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.49 , pp. 17174-17179
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3    Lohse, C.M.4    Dong, H.5    Webster, W.S.6
  • 48
    • 27644562256 scopus 로고    scopus 로고
    • Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma
    • R.H. Thompson, M.D. Gillett, J.C. Cheville, C.M. Lohse, H. Dong, and W.S. Webster et al. Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma Cancer 104 10 2005 2084 2091
    • (2005) Cancer , vol.104 , Issue.10 , pp. 2084-2091
    • Thompson, R.H.1    Gillett, M.D.2    Cheville, J.C.3    Lohse, C.M.4    Dong, H.5    Webster, W.S.6
  • 49
    • 33645736792 scopus 로고    scopus 로고
    • Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
    • R.H. Thompson, S.M. Kuntz, B.C. Leibovich, H. Dong, C.M. Lohse, and W.S. Webster et al. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up Cancer Res 66 7 2006 3381 3385
    • (2006) Cancer Res , vol.66 , Issue.7 , pp. 3381-3385
    • Thompson, R.H.1    Kuntz, S.M.2    Leibovich, B.C.3    Dong, H.4    Lohse, C.M.5    Webster, W.S.6
  • 50
    • 33846852187 scopus 로고    scopus 로고
    • Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy
    • R.H. Thompson, H. Dong, and E.D. Kwon Implications of B7-H1 expression in clear cell carcinoma of the kidney for prognostication and therapy Clin Cancer Res 13 2 Pt 2 2007 709s 715s
    • (2007) Clin Cancer Res , vol.13 , Issue.2 PART 2
    • Thompson, R.H.1    Dong, H.2    Kwon, E.D.3
  • 51
    • 51049096135 scopus 로고    scopus 로고
    • T-cell coregulatory molecule expression in urothelial cell carcinoma: Clinicopathologic correlations and association with survival
    • S.A. Boorjian, Y. Sheinin, P.L. Crispen, S.A. Farmer, C.M. Lohse, and S.M. Kuntz et al. T-cell coregulatory molecule expression in urothelial cell carcinoma: clinicopathologic correlations and association with survival Clin Cancer Res 14 15 2008 4800 4808
    • (2008) Clin Cancer Res , vol.14 , Issue.15 , pp. 4800-4808
    • Boorjian, S.A.1    Sheinin, Y.2    Crispen, P.L.3    Farmer, S.A.4    Lohse, C.M.5    Kuntz, S.M.6
  • 52
    • 34247113727 scopus 로고    scopus 로고
    • PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: Associations with localized stage progression
    • B.A. Inman, T.J. Sebo, X. Frigola, H. Dong, E.J. Bergstralh, and I. Frank et al. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression Cancer 109 8 2007 1499 1505
    • (2007) Cancer , vol.109 , Issue.8 , pp. 1499-1505
    • Inman, B.A.1    Sebo, T.J.2    Frigola, X.3    Dong, H.4    Bergstralh, E.J.5    Frank, I.6
  • 53
    • 34248586083 scopus 로고    scopus 로고
    • Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers
    • J. Nakanishi, Y. Wada, K. Matsumoto, M. Azuma, K. Kikuchi, and S. Ueda Overexpression of B7-H1 (PD-L1) significantly associates with tumor grade and postoperative prognosis in human urothelial cancers Cancer Immunol Immunother 56 8 2007 1173 1182
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.8 , pp. 1173-1182
    • Nakanishi, J.1    Wada, Y.2    Matsumoto, K.3    Azuma, M.4    Kikuchi, K.5    Ueda, S.6
  • 55
    • 77950283280 scopus 로고    scopus 로고
    • Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
    • R. Hino, K. Kabashima, Y. Kato, H. Yagi, M. Nakamura, and T. Honjo et al. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma Cancer 116 7 2010 1757 1766
    • (2010) Cancer , vol.116 , Issue.7 , pp. 1757-1766
    • Hino, R.1    Kabashima, K.2    Kato, Y.3    Yagi, H.4    Nakamura, M.5    Honjo, T.6
  • 56
    • 84859128199 scopus 로고    scopus 로고
    • Colocalization of inflammatory response with B7-H1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape
    • J.M. Taube, R.A. Anders, G.D. Young, H. Xu, R. Sharma, and T.L. McMiller et al. Colocalization of inflammatory response with B7-H1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape Sci Transl Med 4 127 2012 127ra37
    • (2012) Sci Transl Med , vol.4 , Issue.127
    • Taube, J.M.1    Anders, R.A.2    Young, G.D.3    Xu, H.4    Sharma, R.5    McMiller, T.L.6
  • 57
    • 84863433445 scopus 로고    scopus 로고
    • The characteristic expression of B7-associated proteins in Langerhans cell sarcoma
    • H. Li, C. Wang, G. Guo, C. Gao, Y. Wu, and Y. Chen The characteristic expression of B7-associated proteins in Langerhans cell sarcoma Acta Histochem 114 7 2012 733 743
    • (2012) Acta Histochem , vol.114 , Issue.7 , pp. 733-743
    • Li, H.1    Wang, C.2    Guo, G.3    Gao, C.4    Wu, Y.5    Chen, Y.6
  • 58
    • 60149109928 scopus 로고    scopus 로고
    • PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients
    • T. Kozako, M. Yoshimitsu, H. Fujiwara, I. Masamoto, S. Horai, and Y. White et al. PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients Leukemia 23 2 2009 375 382
    • (2009) Leukemia , vol.23 , Issue.2 , pp. 375-382
    • Kozako, T.1    Yoshimitsu, M.2    Fujiwara, H.3    Masamoto, I.4    Horai, S.5    White, Y.6
  • 59
    • 70349234325 scopus 로고    scopus 로고
    • B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders
    • R.A. Wilcox, A.L. Feldman, D.A. Wada, Z.Z. Yang, N.I. Comfere, and H. Dong et al. B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders Blood 114 10 2009 2149 2158
    • (2009) Blood , vol.114 , Issue.10 , pp. 2149-2158
    • Wilcox, R.A.1    Feldman, A.L.2    Wada, D.A.3    Yang, Z.Z.4    Comfere, N.I.5    Dong, H.6
  • 60
    • 33745195264 scopus 로고    scopus 로고
    • The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans
    • H.R. Salih, S. Wintterle, M. Krusch, A. Kroner, Y.H. Huang, and L. Chen et al. The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans Exp Hematol 34 7 2006 888 894
    • (2006) Exp Hematol , vol.34 , Issue.7 , pp. 888-894
    • Salih, H.R.1    Wintterle, S.2    Krusch, M.3    Kroner, A.4    Huang, Y.H.5    Chen, L.6
  • 61
    • 70450065209 scopus 로고    scopus 로고
    • Real-time quantitative PCR detecting B7-H1 gene expression in leukemia cells and its clinical implications
    • [in Chinese]
    • X. Li, Y.F. Wang, W. Ge, Z.J. Li, Z. Yu, and Y.T. Li et al. Real-time quantitative PCR detecting B7-H1 gene expression in leukemia cells and its clinical implications Zhonghua Xue Ye Xue Za Zhi 28 12 2007 837 840 [in Chinese]
    • (2007) Zhonghua Xue Ye Xue Za Zhi , vol.28 , Issue.12 , pp. 837-840
    • Li, X.1    Wang, Y.F.2    Ge, W.3    Li, Z.J.4    Yu, Z.5    Li, Y.T.6
  • 62
    • 56149113642 scopus 로고    scopus 로고
    • Clinical significance of B7-H1 (PD-L1) expression in human acute leukemia
    • X. Chen, S. Liu, L. Wang, W. Zhang, Y. Ji, and X. Ma Clinical significance of B7-H1 (PD-L1) expression in human acute leukemia Cancer Biol Ther 7 5 2008 622 627
    • (2008) Cancer Biol Ther , vol.7 , Issue.5 , pp. 622-627
    • Chen, X.1    Liu, S.2    Wang, L.3    Zhang, W.4    Ji, Y.5    Ma, X.6
  • 63
    • 84878081768 scopus 로고    scopus 로고
    • Expression of B7-H1 gene in leukemia cells and its clinical significance
    • in Chinese]
    • X. Li, W.J. Sun, Y. Xu, Z.J. Li, Z. Yu, and S.H. Deng et al. Expression of B7-H1 gene in leukemia cells and its clinical significance Zhongguo Shi Yan Xue Ye Xue Za Zhi 20 3 2012 541 544 in Chinese]
    • (2012) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.20 , Issue.3 , pp. 541-544
    • Li, X.1    Sun, W.J.2    Xu, Y.3    Li, Z.J.4    Yu, Z.5    Deng, S.H.6
  • 64
    • 67349109903 scopus 로고    scopus 로고
    • B7-H1 up-regulation on dendritic-like leukemia cells suppresses T cell immune function through modulation of IL-10/IL-12 production and generation of Treg cells
    • W. Ge, X. Ma, X. Li, Y. Wang, C. Li, and H. Meng et al. B7-H1 up-regulation on dendritic-like leukemia cells suppresses T cell immune function through modulation of IL-10/IL-12 production and generation of Treg cells Leuk Res 33 7 2009 948 957
    • (2009) Leuk Res , vol.33 , Issue.7 , pp. 948-957
    • Ge, W.1    Ma, X.2    Li, X.3    Wang, Y.4    Li, C.5    Meng, H.6
  • 65
    • 77957657109 scopus 로고    scopus 로고
    • In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors
    • C. Berthon, V. Driss, J. Liu, K. Kuranda, X. Leleu, and N. Jouy et al. In acute myeloid leukemia, B7-H1 (PD-L1) protection of blasts from cytotoxic T cells is induced by TLR ligands and interferon-gamma and can be reversed using MEK inhibitors Cancer Immunol Immunother 59 12 2010 1839 1849
    • (2010) Cancer Immunol Immunother , vol.59 , Issue.12 , pp. 1839-1849
    • Berthon, C.1    Driss, V.2    Liu, J.3    Kuranda, K.4    Leleu, X.5    Jouy, N.6
  • 66
    • 79960967930 scopus 로고    scopus 로고
    • PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation
    • W.J. Norde, F. Maas, W. Hobo, A. Korman, M. Quigley, and M.G. Kester et al. PD-1/PD-L1 interactions contribute to functional T-cell impairment in patients who relapse with cancer after allogeneic stem cell transplantation Cancer Res 71 15 2011 5111 5122
    • (2011) Cancer Res , vol.71 , Issue.15 , pp. 5111-5122
    • Norde, W.J.1    Maas, F.2    Hobo, W.3    Korman, A.4    Quigley, M.5    Kester, M.G.6
  • 67
    • 84891530445 scopus 로고    scopus 로고
    • B7-H1, a prognostic factor for patient's response to therapy of acute myeloid leukemia
    • W.J. Sun, and X. Li B7-H1, a prognostic factor for patient's response to therapy of acute myeloid leukemia Zhongguo Shi Yan Xue Ye Xue Za Zhi 20 6 2012 1332 1335
    • (2012) Zhongguo Shi Yan Xue Ye Xue Za Zhi , vol.20 , Issue.6 , pp. 1332-1335
    • Sun, W.J.1    Li, X.2
  • 68
    • 84859817335 scopus 로고    scopus 로고
    • Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia
    • M. Grzywnowicz, J. Zaleska, D. Mertens, W. Tomczak, P. Wlasiuk, and K. Kosior et al. Programmed death-1 and its ligand are novel immunotolerant molecules expressed on leukemic B cells in chronic lymphocytic leukemia PLoS ONE 7 4 2012 e35178
    • (2012) PLoS ONE , vol.7 , Issue.4 , pp. 35178
    • Grzywnowicz, M.1    Zaleska, J.2    Mertens, D.3    Tomczak, W.4    Wlasiuk, P.5    Kosior, K.6
  • 69
    • 79960218752 scopus 로고    scopus 로고
    • Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade
    • W.H. Hallett, W. Jing, W.R. Drobyski, and B.D. Johnson Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade Biol Blood Marrow Transplant 17 8 2011 1133 1145
    • (2011) Biol Blood Marrow Transplant , vol.17 , Issue.8 , pp. 1133-1145
    • Hallett, W.H.1    Jing, W.2    Drobyski, W.R.3    Johnson, B.D.4
  • 70
    • 84873569613 scopus 로고    scopus 로고
    • Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma
    • H. Tamura, M. Ishibashi, T. Yamashita, S. Tanosaki, N. Okuyama, and A. Kondo et al. Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma Leukemia 27 2 2013 464 472
    • (2013) Leukemia , vol.27 , Issue.2 , pp. 464-472
    • Tamura, H.1    Ishibashi, M.2    Yamashita, T.3    Tanosaki, S.4    Okuyama, N.5    Kondo, A.6
  • 71
    • 13744253833 scopus 로고    scopus 로고
    • Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: Implications for tumor immunotherapy
    • C. Blank, T.F. Gajewski, and A. Mackensen Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy Cancer Immunol Immunother 54 4 2005 307 314
    • (2005) Cancer Immunol Immunother , vol.54 , Issue.4 , pp. 307-314
    • Blank, C.1    Gajewski, T.F.2    MacKensen, A.3
  • 72
    • 34347400169 scopus 로고    scopus 로고
    • Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
    • J. Liu, A. Hamrouni, D. Wolowiec, V. Coiteux, K. Kuliczkowski, and D. Hetuin et al. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway Blood 110 1 2007 296 304
    • (2007) Blood , vol.110 , Issue.1 , pp. 296-304
    • Liu, J.1    Hamrouni, A.2    Wolowiec, D.3    Coiteux, V.4    Kuliczkowski, K.5    Hetuin, D.6
  • 73
    • 13444270323 scopus 로고    scopus 로고
    • Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity
    • F. Hirano, K. Kaneko, H. Tamura, H. Dong, S. Wang, and M. Ichikawa et al. Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity Cancer Res 65 3 2005 1089 1096
    • (2005) Cancer Res , vol.65 , Issue.3 , pp. 1089-1096
    • Hirano, F.1    Kaneko, K.2    Tamura, H.3    Dong, H.4    Wang, S.5    Ichikawa, M.6
  • 75
    • 0003619249 scopus 로고    scopus 로고
    • American Cancer Society [accessed 05/06, 2013]
    • Breast Cancer Facts and Figures 2003-2004. American Cancer Society. Available at: < http://www.cancer.org/acs/groups/content/@nho/documents/ document/caff2003brfpwsecuredpdf.pdf >; 2004 [accessed 05/06, 2013].
    • (2004) Breast Cancer Facts and Figures 2003-2004
  • 77
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • H. zur Hausen Papillomaviruses and cancer: from basic studies to clinical application Nat Rev Cancer 2 5 2002 342 350
    • (2002) Nat Rev Cancer , vol.2 , Issue.5 , pp. 342-350
    • Zur Hausen, H.1
  • 78
    • 0029041842 scopus 로고
    • Prevalence of human papillomavirus in cervical cancer: A worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group
    • F.X. Bosch, M.M. Manos, N. Muñoz, M. Sherman, A.M. Jansen, and J. Peto et al. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. International biological study on cervical cancer (IBSCC) Study Group J Natl Cancer Inst 87 11 1995 796 802
    • (1995) J Natl Cancer Inst , vol.87 , Issue.11 , pp. 796-802
    • Bosch, F.X.1    Manos, M.M.2    Muñoz, N.3    Sherman, M.4    Jansen, A.M.5    Peto, J.6
  • 79
    • 0033844534 scopus 로고    scopus 로고
    • Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens
    • M. Nakagawa, D.P. Stites, S. Patel, S. Farhat, M. Scott, and N.K. Hills et al. Persistence of human papillomavirus type 16 infection is associated with lack of cytotoxic T lymphocyte response to the E6 antigens J Infect Dis 182 2 2000 595 598
    • (2000) J Infect Dis , vol.182 , Issue.2 , pp. 595-598
    • Nakagawa, M.1    Stites, D.P.2    Patel, S.3    Farhat, S.4    Scott, M.5    Hills, N.K.6
  • 80
    • 0037309971 scopus 로고    scopus 로고
    • Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter
    • M.J. Welters, A. de Jong, S.J. van den Eeden, J.M. van der Hulst, K.M. Kwappenberg, and S. Hassane et al. Frequent display of human papillomavirus type 16 E6-specific memory t-Helper cells in the healthy population as witness of previous viral encounter Cancer Res 63 3 2003 636 641
    • (2003) Cancer Res , vol.63 , Issue.3 , pp. 636-641
    • Welters, M.J.1    De Jong, A.2    Van Den Eeden, S.J.3    Van Der Hulst, J.M.4    Kwappenberg, K.M.5    Hassane, S.6
  • 81
    • 3442888540 scopus 로고    scopus 로고
    • Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6
    • A. de Jong, M.I. van Poelgeest, J.M. van der Hulst, J.W. Drijfhout, G.J. Fleuren, and C.J. Melief et al. Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6 Cancer Res 64 15 2004 5449 5455
    • (2004) Cancer Res , vol.64 , Issue.15 , pp. 5449-5455
    • De Jong, A.1    Van Poelgeest, M.I.2    Van Der Hulst, J.M.3    Drijfhout, J.W.4    Fleuren, G.J.5    Melief, C.J.6
  • 82
    • 84877058675 scopus 로고    scopus 로고
    • Systemic treatment and medical management of metastatic squamous cell carcinoma of the head and neck: Review of the literature and proposal for management changes
    • F. Peyrade, D. Cupissol, L. Geoffrois, F. Rolland, C. Borel, and C. Ciais et al. Systemic treatment and medical management of metastatic squamous cell carcinoma of the head and neck: review of the literature and proposal for management changes Oral Oncol 49 6 2013 482 491
    • (2013) Oral Oncol , vol.49 , Issue.6 , pp. 482-491
    • Peyrade, F.1    Cupissol, D.2    Geoffrois, L.3    Rolland, F.4    Borel, C.5    Ciais, C.6
  • 83
    • 84875930205 scopus 로고    scopus 로고
    • Neurosurgery and prognosis in patients with radiation-induced brain injury after nasopharyngeal carcinoma radiotherapy: A follow-up study
    • Y. Li, X. Shi, X. Rong, Y. Peng, and Y. Tang Neurosurgery and prognosis in patients with radiation-induced brain injury after nasopharyngeal carcinoma radiotherapy: a follow-up study Radiat Oncol 11 8 2013 88
    • (2013) Radiat Oncol , vol.11 , Issue.8 , pp. 88
    • Li, Y.1    Shi, X.2    Rong, X.3    Peng, Y.4    Tang, Y.5
  • 86
    • 67650603396 scopus 로고    scopus 로고
    • Costimulatory molecule B7-H1 on the immune escape of bladder cancer and its clinical significance
    • Y. Wang, Q. Zhuang, S. Zhou, Z. Hu, and R. Lan Costimulatory molecule B7-H1 on the immune escape of bladder cancer and its clinical significance J Huazhong Univ Sci Technolog Med Sci 29 1 2009 77 79
    • (2009) J Huazhong Univ Sci Technolog Med Sci , vol.29 , Issue.1 , pp. 77-79
    • Wang, Y.1    Zhuang, Q.2    Zhou, S.3    Hu, Z.4    Lan, R.5
  • 87
    • 84880273186 scopus 로고    scopus 로고
    • Potential biofluid markers and treatment targets for renal cell carcinoma
    • H.I. Wettersten, and R.H. Weiss Potential biofluid markers and treatment targets for renal cell carcinoma Nat Rev Urol 10 6 2013 336 344
    • (2013) Nat Rev Urol , vol.10 , Issue.6 , pp. 336-344
    • Wettersten, H.I.1    Weiss, R.H.2
  • 89
    • 41749091806 scopus 로고    scopus 로고
    • B7-H1 expression in Wilms tumor: Correlation with tumor biology and disease recurrence
    • [discussion 1959-60]
    • J.C. Routh, R.A. Ashley, T.J. Sebo, C.M. Lohse, D.A. Husmann, and S.A. Kramer et al. B7-H1 expression in Wilms tumor: correlation with tumor biology and disease recurrence J Urol 179 5 2008 1954 1959 [discussion 1959-60]
    • (2008) J Urol , vol.179 , Issue.5 , pp. 1954-1959
    • Routh, J.C.1    Ashley, R.A.2    Sebo, T.J.3    Lohse, C.M.4    Husmann, D.A.5    Kramer, S.A.6
  • 90
    • 84859914846 scopus 로고    scopus 로고
    • Narrowing the knowledge gaps for melanoma
    • A. Slipicevic, and M. Herlyn Narrowing the knowledge gaps for melanoma Ups J Med Sci 117 2 2012 237 243
    • (2012) Ups J Med Sci , vol.117 , Issue.2 , pp. 237-243
    • Slipicevic, A.1    Herlyn, M.2
  • 91
    • 4344656396 scopus 로고    scopus 로고
    • Management of cutaneous melanoma
    • H. Tsao, M.B. Atkins, and A.J. Sober Management of cutaneous melanoma N Engl J Med 351 10 2004 998 1012
    • (2004) N Engl J Med , vol.351 , Issue.10 , pp. 998-1012
    • Tsao, H.1    Atkins, M.B.2    Sober, A.J.3
  • 96
    • 0016386433 scopus 로고
    • Letter: Two cases of T-cell chronic lymphocytic leukemia in Japan
    • J. Yodoi, K. Takatsuki, and T. Masuda Letter: two cases of T-cell chronic lymphocytic leukemia in Japan N Engl J Med 290 10 1974 572 573
    • (1974) N Engl J Med , vol.290 , Issue.10 , pp. 572-573
    • Yodoi, J.1    Takatsuki, K.2    Masuda, T.3
  • 98
    • 79960318715 scopus 로고    scopus 로고
    • Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells
    • D.J. Andorsky, R.E. Yamada, J. Said, G.S. Pinkus, D.J. Betting, and J.M. Timmerman Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells Clin Cancer Res 17 13 2011 4232 4244
    • (2011) Clin Cancer Res , vol.17 , Issue.13 , pp. 4232-4244
    • Andorsky, D.J.1    Yamada, R.E.2    Said, J.3    Pinkus, G.S.4    Betting, D.J.5    Timmerman, J.M.6
  • 100
    • 33645013793 scopus 로고    scopus 로고
    • Problems monitoring response in multiple myeloma
    • C.D. Collins Problems monitoring response in multiple myeloma Cancer Imaging 5 Spec No. A 2005 S119 S126
    • (2005) Cancer Imaging , vol.5 , Issue.SPEC NO. A
    • Collins, C.D.1
  • 101
    • 33748881940 scopus 로고    scopus 로고
    • Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation
    • H. Kuipers, F. Muskens, M. Willart, D. Hijdra, F.B. van Assema, and A.J. Coyle et al. Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation Eur J Immunol 36 9 2006 2472 2482
    • (2006) Eur J Immunol , vol.36 , Issue.9 , pp. 2472-2482
    • Kuipers, H.1    Muskens, F.2    Willart, M.3    Hijdra, D.4    Van Assema, F.B.5    Coyle, A.J.6
  • 102
    • 2142711024 scopus 로고    scopus 로고
    • The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells
    • A. Nakazawa, I. Dotan, J. Brimnes, M. Allez, L. Shao, and F. Tsushima et al. The expression and function of costimulatory molecules B7H and B7-H1 on colonic epithelial cells Gastroenterology 126 5 2004 1347 1357
    • (2004) Gastroenterology , vol.126 , Issue.5 , pp. 1347-1357
    • Nakazawa, A.1    Dotan, I.2    Brimnes, J.3    Allez, M.4    Shao, L.5    Tsushima, F.6
  • 103
    • 85056049250 scopus 로고    scopus 로고
    • Costimulation and pancreatic autoimmunity: The PD-1/PD-L conundrum
    • D. Yadav, and N. Sarvetnick Costimulation and pancreatic autoimmunity: the PD-1/PD-L conundrum Rev Diabet Stud 3 1 2006 6 10
    • (2006) Rev Diabet Stud , vol.3 , Issue.1 , pp. 6-10
    • Yadav, D.1    Sarvetnick, N.2
  • 104
    • 20444454594 scopus 로고    scopus 로고
    • Sinomenine inhibits B7-H1 and B7-DC expression on human renal tubular epithelial cells
    • Y. Chen, J. Li, J. Zhang, T. Zhao, L. Zou, and Y. Tang et al. Sinomenine inhibits B7-H1 and B7-DC expression on human renal tubular epithelial cells Int Immunopharmacol 5 9 2005 1446 1457
    • (2005) Int Immunopharmacol , vol.5 , Issue.9 , pp. 1446-1457
    • Chen, Y.1    Li, J.2    Zhang, J.3    Zhao, T.4    Zou, L.5    Tang, Y.6
  • 105
    • 33750350800 scopus 로고    scopus 로고
    • B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts
    • J. Hori, M. Wang, M. Miyashita, K. Tanemoto, H. Takahashi, and T. Takemori et al. B7-H1-induced apoptosis as a mechanism of immune privilege of corneal allografts J Immunol 177 9 2006 5928 5935
    • (2006) J Immunol , vol.177 , Issue.9 , pp. 5928-5935
    • Hori, J.1    Wang, M.2    Miyashita, M.3    Tanemoto, K.4    Takahashi, H.5    Takemori, T.6
  • 106
    • 33644548654 scopus 로고    scopus 로고
    • Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells
    • G. Raimondi, W.J. Shufesky, D. Tokita, A.E. Morelli, and A.W. Thomson Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells J Immunol 176 5 2006 2808 2816
    • (2006) J Immunol , vol.176 , Issue.5 , pp. 2808-2816
    • Raimondi, G.1    Shufesky, W.J.2    Tokita, D.3    Morelli, A.E.4    Thomson, A.W.5
  • 107
    • 0033571785 scopus 로고    scopus 로고
    • In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
    • D. Bell, P. Chomarat, D. Broyles, G. Netto, G.M. Harb, and S. Lebecque et al. In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas J Exp Med 190 10 1999 1417 1426
    • (1999) J Exp Med , vol.190 , Issue.10 , pp. 1417-1426
    • Bell, D.1    Chomarat, P.2    Broyles, D.3    Netto, G.4    Harb, G.M.5    Lebecque, S.6
  • 108
    • 70349231487 scopus 로고    scopus 로고
    • Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells
    • M.B. Lutz, and C. Kurts Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells Eur J Immunol 39 9 2009 2325 2330
    • (2009) Eur J Immunol , vol.39 , Issue.9 , pp. 2325-2330
    • Lutz, M.B.1    Kurts, C.2
  • 112
    • 17844396955 scopus 로고    scopus 로고
    • Current advances, problems and prospects for vaccine-based immunotherapy in follicular non-Hodgkin's lymphoma
    • S. Dermime, and M.D. Aljurf Current advances, problems and prospects for vaccine-based immunotherapy in follicular non-Hodgkin's lymphoma Leuk Lymphoma 46 4 2005 497 507
    • (2005) Leuk Lymphoma , vol.46 , Issue.4 , pp. 497-507
    • Dermime, S.1    Aljurf, M.D.2
  • 113
    • 0035059417 scopus 로고    scopus 로고
    • Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation
    • B. Salomon, and J.A. Bluestone Complexities of CD28/B7: CTLA-4 costimulatory pathways in autoimmunity and transplantation Annu Rev Immunol 19 2001 225 252
    • (2001) Annu Rev Immunol , vol.19 , pp. 225-252
    • Salomon, B.1    Bluestone, J.A.2
  • 114
    • 33847422253 scopus 로고    scopus 로고
    • T cell costimulatory and inhibitory receptors as therapeutic targets for inducing anti-tumor immunity
    • J. Foell, B. Hewes, and R.S. Mittler T cell costimulatory and inhibitory receptors as therapeutic targets for inducing anti-tumor immunity Curr Cancer Drug Targets 7 1 2007 55 70
    • (2007) Curr Cancer Drug Targets , vol.7 , Issue.1 , pp. 55-70
    • Foell, J.1    Hewes, B.2    Mittler, R.S.3
  • 115
    • 81555226044 scopus 로고    scopus 로고
    • The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion
    • K.A. Hofmeyer, H. Jeon, and X. Zang The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion J Biomed Biotechnol 2011 2011 451694
    • (2011) J Biomed Biotechnol , vol.2011 , pp. 451694
    • Hofmeyer, K.A.1    Jeon, H.2    Zang, X.3
  • 116
    • 3142688997 scopus 로고    scopus 로고
    • SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation
    • J.M. Chemnitz, R.V. Parry, K.E. Nichols, C.H. June, and J.L. Riley SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation J Immunol 173 2 2004 945 954
    • (2004) J Immunol , vol.173 , Issue.2 , pp. 945-954
    • Chemnitz, J.M.1    Parry, R.V.2    Nichols, K.E.3    June, C.H.4    Riley, J.L.5
  • 117
    • 70350433514 scopus 로고    scopus 로고
    • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
    • B.T. Fife, K.E. Pauken, T.N. Eagar, T. Obu, J. Wu, and Q. Tang et al. Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal Nat Immunol 10 11 2009 1185 1192
    • (2009) Nat Immunol , vol.10 , Issue.11 , pp. 1185-1192
    • Fife, B.T.1    Pauken, K.E.2    Eagar, T.N.3    Obu, T.4    Wu, J.5    Tang, Q.6
  • 118
    • 0034596948 scopus 로고    scopus 로고
    • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
    • G.J. Freeman, A.J. Long, Y. Iwai, K. Bourque, T. Chernova, and H. Nishimura et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation J Exp Med 192 7 2000 1027 1034
    • (2000) J Exp Med , vol.192 , Issue.7 , pp. 1027-1034
    • Freeman, G.J.1    Long, A.J.2    Iwai, Y.3    Bourque, K.4    Chernova, T.5    Nishimura, H.6
  • 119
    • 0036207926 scopus 로고    scopus 로고
    • PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2
    • L. Carter, L.A. Fouser, J. Jussif, L. Fitz, B. Deng, and C.R. Wood et al. PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2 Eur J Immunol 32 3 2002 634 643
    • (2002) Eur J Immunol , vol.32 , Issue.3 , pp. 634-643
    • Carter, L.1    Fouser, L.A.2    Jussif, J.3    Fitz, L.4    Deng, B.5    Wood, C.R.6
  • 120
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • S. Hori, T. Nomura, and S. Sakaguchi Control of regulatory T cell development by the transcription factor Foxp3 Science 299 5609 2003 1057 1061
    • (2003) Science , vol.299 , Issue.5609 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 121
    • 0035525739 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) cells: A naturally occurring population of regulatory T cells
    • W.F. Ng, P.J. Duggan, F. Ponchel, G. Matarese, G. Lombardi, and A.D. Edwards et al. Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells Blood 98 9 2001 2736 2744
    • (2001) Blood , vol.98 , Issue.9 , pp. 2736-2744
    • Ng, W.F.1    Duggan, P.J.2    Ponchel, F.3    Matarese, G.4    Lombardi, G.5    Edwards, A.D.6
  • 122
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • A.M. Thornton, and E.M. Shevach CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J Exp Med 188 2 1998 287 296
    • (1998) J Exp Med , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 123
    • 12344307563 scopus 로고    scopus 로고
    • Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus
    • S. Liang, P. Alard, Y. Zhao, S. Parnell, S.L. Clark, and M.M. Kosiewicz Conversion of CD4+ CD25- cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus J Exp Med 201 1 2005 127 137
    • (2005) J Exp Med , vol.201 , Issue.1 , pp. 127-137
    • Liang, S.1    Alard, P.2    Zhao, Y.3    Parnell, S.4    Clark, S.L.5    Kosiewicz, M.M.6
  • 124
    • 34147131338 scopus 로고    scopus 로고
    • Involvement of the programmed death-1/programmed death-1 ligand pathway in CD4+CD25+ regulatory T-cell activity to suppress alloimmune responses
    • Y. Kitazawa, M. Fujino, Q. Wang, H. Kimura, M. Azuma, and M. Kubo et al. Involvement of the programmed death-1/programmed death-1 ligand pathway in CD4+CD25+ regulatory T-cell activity to suppress alloimmune responses Transplantation 83 6 2007 774 782
    • (2007) Transplantation , vol.83 , Issue.6 , pp. 774-782
    • Kitazawa, Y.1    Fujino, M.2    Wang, Q.3    Kimura, H.4    Azuma, M.5    Kubo, M.6
  • 125
    • 82655184651 scopus 로고    scopus 로고
    • The PDL1-PD1 axis converts human TH1 cells into regulatory T cells
    • S. Amarnath, C.W. Mangus, J.C. Wang, F. Wei, A. He, and V. Kapoor et al. The PDL1-PD1 axis converts human TH1 cells into regulatory T cells Sci Transl Med 3 111 2011 111ra120
    • (2011) Sci Transl Med , vol.3 , Issue.111
    • Amarnath, S.1    Mangus, C.W.2    Wang, J.C.3    Wei, F.4    He, A.5    Kapoor, V.6
  • 126
    • 33847393154 scopus 로고    scopus 로고
    • Immunoregulatory role of B7-H1 in chronicity of inflammatory responses
    • H. Dong, and X. Chen Immunoregulatory role of B7-H1 in chronicity of inflammatory responses Cell Mol Immunol 3 3 2006 179 187
    • (2006) Cell Mol Immunol , vol.3 , Issue.3 , pp. 179-187
    • Dong, H.1    Chen, X.2
  • 128
    • 0034676249 scopus 로고    scopus 로고
    • Clinical impact of intratumoral natural killer cell and dendritic cell infiltration in gastric cancer
    • S. Ishigami, S. Natsugoe, K. Tokuda, A. Nakajo, C. Xiangming, and H. Iwashige et al. Clinical impact of intratumoral natural killer cell and dendritic cell infiltration in gastric cancer Cancer Lett 159 1 2000 103 108
    • (2000) Cancer Lett , vol.159 , Issue.1 , pp. 103-108
    • Ishigami, S.1    Natsugoe, S.2    Tokuda, K.3    Nakajo, A.4    Xiangming, C.5    Iwashige, H.6
  • 129
    • 33745320149 scopus 로고    scopus 로고
    • Mononuclear cell infiltration in clear-cell renal cell carcinoma independently predicts patient survival
    • W.S. Webster, C.M. Lohse, R.H. Thompson, H. Dong, X. Frigola, and D.L. Dicks et al. Mononuclear cell infiltration in clear-cell renal cell carcinoma independently predicts patient survival Cancer 107 1 2006 46 53
    • (2006) Cancer , vol.107 , Issue.1 , pp. 46-53
    • Webster, W.S.1    Lohse, C.M.2    Thompson, R.H.3    Dong, H.4    Frigola, X.5    Dicks, D.L.6
  • 130
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • D.M. Pardoll The blockade of immune checkpoints in cancer immunotherapy Nat Rev Cancer 12 4 2012 252 264
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 252-264
    • Pardoll, D.M.1
  • 131
    • 58249112908 scopus 로고    scopus 로고
    • PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancer
    • C.A. Crane, A. Panner, J.C. Murray, S.P. Wilson, H. Xu, and L. Chen et al. PI(3) kinase is associated with a mechanism of immunoresistance in breast and prostate cancer Oncogene 28 2 2009 306 312
    • (2009) Oncogene , vol.28 , Issue.2 , pp. 306-312
    • Crane, C.A.1    Panner, A.2    Murray, J.C.3    Wilson, S.P.4    Xu, H.5    Chen, L.6
  • 132
    • 67651171652 scopus 로고    scopus 로고
    • Honokiol-mediated inhibition of PI3K/mTOR pathway: A potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function
    • C. Crane, A. Panner, R.O. Pieper, J. Arbiser, and A.T. Parsa Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function J Immunother 32 6 2009 585 592
    • (2009) J Immunother , vol.32 , Issue.6 , pp. 585-592
    • Crane, C.1    Panner, A.2    Pieper, R.O.3    Arbiser, J.4    Parsa, A.T.5
  • 133
    • 58549102319 scopus 로고    scopus 로고
    • Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)
    • M. Marzec, Q. Zhang, A. Goradia, P.N. Raghunath, X. Liu, and M. Paessler et al. Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1) Proc Natl Acad Sci U S A 105 52 2008 20852 20857
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.52 , pp. 20852-20857
    • Marzec, M.1    Zhang, Q.2    Goradia, A.3    Raghunath, P.N.4    Liu, X.5    Paessler, M.6
  • 134
    • 0037111483 scopus 로고    scopus 로고
    • Expression of programmed death 1 ligands by murine T cells and APC
    • T. Yamazaki, H. Akiba, H. Iwai, H. Matsuda, M. Aoki, and Y. Tanno et al. Expression of programmed death 1 ligands by murine T cells and APC J Immunol 169 10 2002 5538 5545
    • (2002) J Immunol , vol.169 , Issue.10 , pp. 5538-5545
    • Yamazaki, T.1    Akiba, H.2    Iwai, H.3    Matsuda, H.4    Aoki, M.5    Tanno, Y.6
  • 135
    • 0038302927 scopus 로고    scopus 로고
    • PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
    • P. Loke, and J.P. Allison PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells Proc Natl Acad Sci U S A 100 9 2003 5336 5341
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.9 , pp. 5336-5341
    • Loke, P.1    Allison, J.P.2
  • 136
    • 24344488326 scopus 로고    scopus 로고
    • Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells
    • J. Kim, A.C. Myers, L. Chen, D.M. Pardoll, Q.A. Truong-Tran, and A.P. Lane et al. Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells Am J Respir Cell Mol Biol 33 3 2005 280 289
    • (2005) Am J Respir Cell Mol Biol , vol.33 , Issue.3 , pp. 280-289
    • Kim, J.1    Myers, A.C.2    Chen, L.3    Pardoll, D.M.4    Truong-Tran, Q.A.5    Lane, A.P.6
  • 137
    • 26844552926 scopus 로고    scopus 로고
    • IFN-gamma regulates the expression of B7-H1 in dermal fibroblast cells
    • S.K. Lee, S.H. Seo, B.S. Kim, C.D. Kim, J.H. Lee, and J.S. Kang et al. IFN-gamma regulates the expression of B7-H1 in dermal fibroblast cells J Dermatol Sci 40 2 2005 95 103
    • (2005) J Dermatol Sci , vol.40 , Issue.2 , pp. 95-103
    • Lee, S.K.1    Seo, S.H.2    Kim, B.S.3    Kim, C.D.4    Lee, J.H.5    Kang, J.S.6
  • 138
    • 82355175850 scopus 로고    scopus 로고
    • Dual biological effects of the cytokines interleukin-10 and interferon-γ
    • C.M. Wilke, S. Wei, L. Wang, I. Kryczek, J. Kao, and W. Zou Dual biological effects of the cytokines interleukin-10 and interferon-γ Cancer Immunol Immunother 60 11 2011 1529 1541
    • (2011) Cancer Immunol Immunother , vol.60 , Issue.11 , pp. 1529-1541
    • Wilke, C.M.1    Wei, S.2    Wang, L.3    Kryczek, I.4    Kao, J.5    Zou, W.6
  • 139
    • 0034068120 scopus 로고    scopus 로고
    • Generation and purification of CD8+ melan-A-specific cytotoxic T lymphocytes for adoptive transfer in tumor immunotherapy
    • M. Oelke, U. Moehrle, J.L. Chen, D. Behringer, V. Cerundolo, and A. Lindemann et al. Generation and purification of CD8+ melan-A-specific cytotoxic T lymphocytes for adoptive transfer in tumor immunotherapy Clin Cancer Res 6 5 2000 1997 2005
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 1997-2005
    • Oelke, M.1    Moehrle, U.2    Chen, J.L.3    Behringer, D.4    Cerundolo, V.5    Lindemann, A.6
  • 140
    • 0141782725 scopus 로고    scopus 로고
    • BTLA: A new inhibitory receptor with a B7-like ligand
    • B.M. Carreno, and M. Collins BTLA: a new inhibitory receptor with a B7-like ligand Trends Immunol 24 10 2003 524 527
    • (2003) Trends Immunol , vol.24 , Issue.10 , pp. 524-527
    • Carreno, B.M.1    Collins, M.2
  • 141
    • 31444451661 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274)
    • S.J. Lee, B.C. Jang, S.W. Lee, Y.I. Yang, S.I. Suh, and Y.M. Park et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274) FEBS Lett 580 3 2006 755 762
    • (2006) FEBS Lett , vol.580 , Issue.3 , pp. 755-762
    • Lee, S.J.1    Jang, B.C.2    Lee, S.W.3    Yang, Y.I.4    Suh, S.I.5    Park, Y.M.6
  • 142
    • 66949175210 scopus 로고    scopus 로고
    • Analysis and expression of a cloned pre-T cell receptor gene. Science. 1994. 266: 1208-1212
    • C. Saint-Ruf, K. Ungewiss, M. Groettrup, L. Bruno, H.J. Fehling, and H. von Boehmer Analysis and expression of a cloned pre-T cell receptor gene. Science. 1994. 266: 1208-1212 J Immunol 182 9 2009 5165 5169
    • (2009) J Immunol , vol.182 , Issue.9 , pp. 5165-5169
    • Saint-Ruf, C.1    Ungewiss, K.2    Groettrup, M.3    Bruno, L.4    Fehling, H.J.5    Von Boehmer, H.6
  • 143
    • 0242422840 scopus 로고    scopus 로고
    • Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: A novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies
    • H. Wiendl, M. Mitsdoerffer, D. Schneider, L. Chen, H. Lochmüller, and A. Melms et al. Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies FASEB J 17 13 2003 1892 1894
    • (2003) FASEB J , vol.17 , Issue.13 , pp. 1892-1894
    • Wiendl, H.1    Mitsdoerffer, M.2    Schneider, D.3    Chen, L.4    Lochmüller, H.5    Melms, A.6
  • 144
    • 54549102285 scopus 로고    scopus 로고
    • Coordinated protein sorting, targeting and distribution in polarized cells
    • I. Mellman, and W.J. Nelson Coordinated protein sorting, targeting and distribution in polarized cells Nat Rev Mol Cell Biol 9 11 2008 833 845
    • (2008) Nat Rev Mol Cell Biol , vol.9 , Issue.11 , pp. 833-845
    • Mellman, I.1    Nelson, W.J.2
  • 145
    • 84871192340 scopus 로고    scopus 로고
    • Molecular pathways: Next-generation immunotherapy-inhibiting programmed death-ligand 1 and programmed death-1
    • D.S. Chen, B.A. Irving, and F.S. Hodi Molecular pathways: next-generation immunotherapy-inhibiting programmed death-ligand 1 and programmed death-1 Clin Cancer Res 18 24 2012 6580 6587
    • (2012) Clin Cancer Res , vol.18 , Issue.24 , pp. 6580-6587
    • Chen, D.S.1    Irving, B.A.2    Hodi, F.S.3
  • 146
    • 84862903106 scopus 로고    scopus 로고
    • Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
    • J.R. Brahmer, S.S. Tykodi, L.Q. Chow, W.J. Hwu, S.L. Topalian, and P. Hwu et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer N Engl J Med 366 26 2012 2455 2465
    • (2012) N Engl J Med , vol.366 , Issue.26 , pp. 2455-2465
    • Brahmer, J.R.1    Tykodi, S.S.2    Chow, L.Q.3    Hwu, W.J.4    Topalian, S.L.5    Hwu, P.6
  • 148
    • 77249095138 scopus 로고    scopus 로고
    • PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions
    • O. Akbari, P. Stock, A.K. Singh, V. Lombardi, W.L. Lee, and G.J. Freeman et al. PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions Mucosal Immunol 3 1 2010 81 91
    • (2010) Mucosal Immunol , vol.3 , Issue.1 , pp. 81-91
    • Akbari, O.1    Stock, P.2    Singh, A.K.3    Lombardi, V.4    Lee, W.L.5    Freeman, G.J.6
  • 149
    • 78049367774 scopus 로고    scopus 로고
    • Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2
    • S. Huber, R. Hoffmann, F. Muskens, and D. Voehringer Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2 Blood 116 17 2010 3311 3320
    • (2010) Blood , vol.116 , Issue.17 , pp. 3311-3320
    • Huber, S.1    Hoffmann, R.2    Muskens, F.3    Voehringer, D.4
  • 150
    • 75149165611 scopus 로고    scopus 로고
    • Regulating immunity and inhibiting tumor growth by the recombinant peptide sPD-1-CH50
    • H. Qiu, S. Liu, C. Xie, J. Long, and Z. Feng Regulating immunity and inhibiting tumor growth by the recombinant peptide sPD-1-CH50 Anticancer Res 29 12 2009 5089 5094
    • (2009) Anticancer Res , vol.29 , Issue.12 , pp. 5089-5094
    • Qiu, H.1    Liu, S.2    Xie, C.3    Long, J.4    Feng, Z.5
  • 152
    • 41549145181 scopus 로고    scopus 로고
    • Immunogenicity of anthracyclines: Moving towards more personalized medicine
    • L. Apetoh, G. Mignot, T. Panaretakis, G. Kroemer, and L. Zitvogel Immunogenicity of anthracyclines: moving towards more personalized medicine Trends Mol Med 14 4 2008 141 151
    • (2008) Trends Mol Med , vol.14 , Issue.4 , pp. 141-151
    • Apetoh, L.1    Mignot, G.2    Panaretakis, T.3    Kroemer, G.4    Zitvogel, L.5
  • 153
    • 52149116029 scopus 로고    scopus 로고
    • Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells
    • M. Liang, and J. Fu Triptolide inhibits interferon-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells Cancer Lett 270 2 2008 337 341
    • (2008) Cancer Lett , vol.270 , Issue.2 , pp. 337-341
    • Liang, M.1    Fu, J.2
  • 154
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialist's Collaborative Group (EBCTCG) May 14-20
    • Early Breast Cancer Trialist's Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005 May 14-20;365(9472):1687-717.
    • (2005) Lancet , vol.365 , Issue.9472 , pp. 1687-1717
  • 155
    • 35848959692 scopus 로고    scopus 로고
    • Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease
    • C. Fermé, H. Eghbali, J.H. Meerwaldt, C. Rieux, J. Bosq, and F. Berger et al. Chemotherapy plus involved-field radiation in early-stage Hodgkin's disease N Engl J Med 357 19 2007 1916 1927
    • (2007) N Engl J Med , vol.357 , Issue.19 , pp. 1916-1927
    • Fermé, C.1    Eghbali, H.2    Meerwaldt, J.H.3    Rieux, C.4    Bosq, J.5    Berger, F.6
  • 156
    • 36849051298 scopus 로고    scopus 로고
    • VCAP-AMP-VECP compared with biweekly CHOP for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group Study JCOG9801
    • K. Tsukasaki, A. Utsunomiya, H. Fukuda, T. Shibata, T. Fukushima, and Y. Takatsuka et al. VCAP-AMP-VECP compared with biweekly CHOP for adult T-cell leukemia-lymphoma: Japan Clinical Oncology Group Study JCOG9801 J Clin Oncol 25 34 2007 5458 5464
    • (2007) J Clin Oncol , vol.25 , Issue.34 , pp. 5458-5464
    • Tsukasaki, K.1    Utsunomiya, A.2    Fukuda, H.3    Shibata, T.4    Fukushima, T.5    Takatsuka, Y.6
  • 157
    • 0021187494 scopus 로고
    • Cellular basis for adriamycin-induced augmentation of cell-mediated cytotoxicity in culture
    • M.J. Ehrke, K. Ryoyama, and S.A. Cohen Cellular basis for adriamycin-induced augmentation of cell-mediated cytotoxicity in culture Cancer Res 44 6 1984 2497 2504
    • (1984) Cancer Res , vol.44 , Issue.6 , pp. 2497-2504
    • Ehrke, M.J.1    Ryoyama, K.2    Cohen, S.A.3
  • 158
    • 0026631127 scopus 로고
    • Adriamycin-induced modulation of host defenses in tumor-bearing mice
    • D.L. Maccubbin, K.R. Wing, K.F. Mace, R.L. Ho, M.J. Ehrke, and E. Mihich Adriamycin-induced modulation of host defenses in tumor-bearing mice Cancer Res 52 13 1992 3572 3576
    • (1992) Cancer Res , vol.52 , Issue.13 , pp. 3572-3576
    • MacCubbin, D.L.1    Wing, K.R.2    MacE, K.F.3    Ho, R.L.4    Ehrke, M.J.5    Mihich, E.6
  • 159
    • 0019499884 scopus 로고
    • Adriamycin-activated macrophages as tumor growth inhibitors
    • J.S. Haskill Adriamycin-activated macrophages as tumor growth inhibitors Cancer Res 41 10 1981 3852 3856
    • (1981) Cancer Res , vol.41 , Issue.10 , pp. 3852-3856
    • Haskill, J.S.1
  • 160
    • 0017115289 scopus 로고
    • Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum
    • H. Yamasaki Pharmacology of sinomenine, an anti-rheumatic alkaloid from Sinomenium acutum Acta Med Okayama 30 1 1976 1 20
    • (1976) Acta Med Okayama , vol.30 , Issue.1 , pp. 1-20
    • Yamasaki, H.1
  • 161
    • 0028676082 scopus 로고
    • Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum
    • L. Liu, J. Riese, K. Resch, and V. Kaever Impairment of macrophage eicosanoid and nitric oxide production by an alkaloid from Sinomenium acutum Arzneimittelforschung 44 11 1994 1223 1226
    • (1994) Arzneimittelforschung , vol.44 , Issue.11 , pp. 1223-1226
    • Liu, L.1    Riese, J.2    Resch, K.3    Kaever, V.4
  • 162
    • 0030268322 scopus 로고    scopus 로고
    • Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine
    • L. Liu, E. Buchner, D. Beitze, C.B. Schmidt-Weber, V. Kaever, and F. Emmrich et al. Amelioration of rat experimental arthritides by treatment with the alkaloid sinomenine Int J Immunopharmacol 18 10 1996 529 543
    • (1996) Int J Immunopharmacol , vol.18 , Issue.10 , pp. 529-543
    • Liu, L.1    Buchner, E.2    Beitze, D.3    Schmidt-Weber, C.B.4    Kaever, V.5    Emmrich, F.6
  • 163
    • 20344370314 scopus 로고    scopus 로고
    • Immunosuppressive effect of Sinomenine on ICAM-1 expression in rat renal allograft rejection
    • Y.B. Dai, H.X. Liu, and L.I. Zao Immunosuppressive effect of Sinomenine on ICAM-1 expression in rat renal allograft rejection Mod J Integr Tradit Chin West Med 12 2003 1358 1361
    • (2003) Mod J Integr Tradit Chin West Med , vol.12 , pp. 1358-1361
    • Dai, Y.B.1    Liu, H.X.2    Zao, L.I.3
  • 164
    • 20344387285 scopus 로고    scopus 로고
    • Effects of Sinomenine on T lymphocyte subsets in rat renal allograft transplantation model
    • P. Yang, L. Yang, and Z. Luo Effects of Sinomenine on T lymphocyte subsets in rat renal allograft transplantation model J Clin Urol 10 2003 620 622
    • (2003) J Clin Urol , vol.10 , pp. 620-622
    • Yang, P.1    Yang, L.2    Luo, Z.3
  • 165
    • 0028040557 scopus 로고
    • Protection by sinomenine against endotoxin-induced fulminant hepatitis in galactosamine-sensitized mice
    • Y. Kondo, F. Takano, K. Yoshida, and H. Hojo Protection by sinomenine against endotoxin-induced fulminant hepatitis in galactosamine-sensitized mice Biochem Pharmacol 48 5 1994 1050 1052
    • (1994) Biochem Pharmacol , vol.48 , Issue.5 , pp. 1050-1052
    • Kondo, Y.1    Takano, F.2    Yoshida, K.3    Hojo, H.4
  • 166
    • 15044342230 scopus 로고    scopus 로고
    • Herbal treatment for renal diseases
    • A. Peng, Y. Gu, and S.Y. Lin Herbal treatment for renal diseases Ann Acad Med Singapore 34 1 2005 44 51
    • (2005) Ann Acad Med Singapore , vol.34 , Issue.1 , pp. 44-51
    • Peng, A.1    Gu, Y.2    Lin, S.Y.3
  • 167
    • 17144397122 scopus 로고    scopus 로고
    • FK506 enhances triptolide-induced down-regulation of cyclooxygenase-2, inducible nitric oxide synthase as well as their products PGE2 and NO in TNF-alpha-stimulated synovial fibroblasts from rheumatoid arthritic patients
    • H. Yao, J. Zhou, D. Li, N. Wu, A. Bader, and S. Höxtermann et al. FK506 enhances triptolide-induced down-regulation of cyclooxygenase-2, inducible nitric oxide synthase as well as their products PGE2 and NO in TNF-alpha-stimulated synovial fibroblasts from rheumatoid arthritic patients Eur J Med Res 10 3 2005 110 116
    • (2005) Eur J Med Res , vol.10 , Issue.3 , pp. 110-116
    • Yao, H.1    Zhou, J.2    Li, D.3    Wu, N.4    Bader, A.5    Höxtermann, S.6
  • 168
    • 0035910420 scopus 로고    scopus 로고
    • Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway
    • W.T. Chang, J.J. Kang, K.Y. Lee, K. Wei, E. Anderson, and S. Gotmare et al. Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway J Biol Chem 276 3 2001 2221 2227
    • (2001) J Biol Chem , vol.276 , Issue.3 , pp. 2221-2227
    • Chang, W.T.1    Kang, J.J.2    Lee, K.Y.3    Wei, K.4    Anderson, E.5    Gotmare, S.6
  • 169
    • 85047700175 scopus 로고    scopus 로고
    • Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells
    • X.H. Jiang, B.C. Wong, M.C. Lin, G.H. Zhu, H.F. Kung, and S.H. Jiang et al. Functional p53 is required for triptolide-induced apoptosis and AP-1 and nuclear factor-kappaB activation in gastric cancer cells Oncogene 20 55 2001 8009 8018
    • (2001) Oncogene , vol.20 , Issue.55 , pp. 8009-8018
    • Jiang, X.H.1    Wong, B.C.2    Lin, M.C.3    Zhu, G.H.4    Kung, H.F.5    Jiang, S.H.6
  • 171
    • 0000597684 scopus 로고    scopus 로고
    • PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells
    • K.Y. Lee, W. Chang, D. Qiu, P.N. Kao, and G.D. Rosen PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells J Biol Chem 274 19 1999 13451 13455
    • (1999) J Biol Chem , vol.274 , Issue.19 , pp. 13451-13455
    • Lee, K.Y.1    Chang, W.2    Qiu, D.3    Kao, P.N.4    Rosen, G.D.5
  • 172
    • 0041333929 scopus 로고    scopus 로고
    • PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2
    • S. Frese, F. Pirnia, D. Miescher, S. Krajewski, M.M. Borner, and J.C. Reed et al. PG490-mediated sensitization of lung cancer cells to Apo2L/TRAIL-induced apoptosis requires activation of ERK2 Oncogene 22 35 2003 5427 5435
    • (2003) Oncogene , vol.22 , Issue.35 , pp. 5427-5435
    • Frese, S.1    Pirnia, F.2    Miescher, D.3    Krajewski, S.4    Borner, M.M.5    Reed, J.C.6
  • 173
    • 0642287879 scopus 로고    scopus 로고
    • PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy
    • J.M. Fidler, K. Li, C. Chung, K. Wei, J.A. Ross, and M. Gao et al. PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy Mol Cancer Ther 2 9 2003 855 862
    • (2003) Mol Cancer Ther , vol.2 , Issue.9 , pp. 855-862
    • Fidler, J.M.1    Li, K.2    Chung, C.3    Wei, K.4    Ross, J.A.5    Gao, M.6
  • 174
    • 30344456419 scopus 로고    scopus 로고
    • Triptolide inhibits B7-H1 expression on proinflammatory factor activated renal tubular epithelial cells by decreasing NF-kappaB transcription
    • Y. Chen, J. Zhang, J. Li, T. Zhao, L. Zou, and Y. Tang et al. Triptolide inhibits B7-H1 expression on proinflammatory factor activated renal tubular epithelial cells by decreasing NF-kappaB transcription Mol Immunol 43 8 2006 1088 1098
    • (2006) Mol Immunol , vol.43 , Issue.8 , pp. 1088-1098
    • Chen, Y.1    Zhang, J.2    Li, J.3    Zhao, T.4    Zou, L.5    Tang, Y.6
  • 175
    • 79952012897 scopus 로고    scopus 로고
    • Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2
    • T. Singh, and S.K. Katiyar Honokiol, a phytochemical from Magnolia spp., inhibits breast cancer cell migration by targeting nitric oxide and cyclooxygenase-2 Int J Oncol 38 3 2011 769 776
    • (2011) Int J Oncol , vol.38 , Issue.3 , pp. 769-776
    • Singh, T.1    Katiyar, S.K.2
  • 176
    • 48749104995 scopus 로고    scopus 로고
    • Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer
    • H. Liu, C. Zang, A. Emde, M.D. Planas-Silva, M. Rosche, and A. Kühnl et al. Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer Eur J Pharmacol 591 1-3 2008 43 51
    • (2008) Eur J Pharmacol , vol.591 , Issue.13 , pp. 43-51
    • Liu, H.1    Zang, C.2    Emde, A.3    Planas-Silva, M.D.4    Rosche, M.5    Kühnl, A.6
  • 177
    • 84865292443 scopus 로고    scopus 로고
    • Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice
    • S.H. Liu, K.B. Wang, K.H. Lan, W.J. Lee, H.C. Pan, and S.M. Wu et al. Calpain/SHP-1 interaction by honokiol dampening peritoneal dissemination of gastric cancer in nu/nu mice PLoS ONE 7 8 2012 e43711
    • (2012) PLoS ONE , vol.7 , Issue.8 , pp. 43711
    • Liu, S.H.1    Wang, K.B.2    Lan, K.H.3    Lee, W.J.4    Pan, H.C.5    Wu, S.M.6
  • 178
    • 42549089095 scopus 로고    scopus 로고
    • Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth
    • M.L. Sheu, S.H. Liu, and K.H. Lan Honokiol induces calpain-mediated glucose-regulated protein-94 cleavage and apoptosis in human gastric cancer cells and reduces tumor growth PLoS ONE 2 10 2007 e1096
    • (2007) PLoS ONE , vol.2 , Issue.10 , pp. 1096
    • Sheu, M.L.1    Liu, S.H.2    Lan, K.H.3
  • 179
    • 84862734639 scopus 로고    scopus 로고
    • Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells
    • S. Ponnurangam, J.M. Mammen, S. Ramalingam, Z. He, Y. Zhang, and S. Umar et al. Honokiol in combination with radiation targets notch signaling to inhibit colon cancer stem cells Mol Cancer Ther 11 4 2012 963 972
    • (2012) Mol Cancer Ther , vol.11 , Issue.4 , pp. 963-972
    • Ponnurangam, S.1    Mammen, J.M.2    Ramalingam, S.3    He, Z.4    Zhang, Y.5    Umar, S.6
  • 181
    • 79959648566 scopus 로고    scopus 로고
    • Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells
    • S. Arora, A. Bhardwaj, S.K. Srivastava, S. Singh, S. McClellan, and B. Wang et al. Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells PLoS ONE 6 6 2011 e21573
    • (2011) PLoS ONE , vol.6 , Issue.6 , pp. 21573
    • Arora, S.1    Bhardwaj, A.2    Srivastava, S.K.3    Singh, S.4    McClellan, S.5    Wang, B.6
  • 183
    • 0037307483 scopus 로고    scopus 로고
    • Cyclooxygenase 2: A molecular target for cancer prevention and treatment
    • K. Subbaramaiah, and A.J. Dannenberg Cyclooxygenase 2: a molecular target for cancer prevention and treatment Trends Pharmacol Sci 24 2 2003 96 102
    • (2003) Trends Pharmacol Sci , vol.24 , Issue.2 , pp. 96-102
    • Subbaramaiah, K.1    Dannenberg, A.J.2
  • 184
    • 14944386105 scopus 로고    scopus 로고
    • Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors
    • D. Foderà, N. D'Alessandro, A. Cusimano, P. Poma, M. Notarbartolo, and N. Lampiasi et al. Induction of apoptosis and inhibition of cell growth in human hepatocellular carcinoma cells by COX-2 inhibitors Ann N Y Acad Sci 1028 2004 440 449
    • (2004) Ann N y Acad Sci , vol.1028 , pp. 440-449
    • Foderà, D.1    D'Alessandro, N.2    Cusimano, A.3    Poma, P.4    Notarbartolo, M.5    Lampiasi, N.6
  • 185
    • 0034026144 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines
    • T. Hida, K. Kozaki, H. Muramatsu, A. Masuda, S. Shimizu, and T. Mitsudomi et al. Cyclooxygenase-2 inhibitor induces apoptosis and enhances cytotoxicity of various anticancer agents in non-small cell lung cancer cell lines Clin Cancer Res 6 5 2000 2006 2011
    • (2000) Clin Cancer Res , vol.6 , Issue.5 , pp. 2006-2011
    • Hida, T.1    Kozaki, K.2    Muramatsu, H.3    Masuda, A.4    Shimizu, S.5    Mitsudomi, T.6
  • 186
    • 0031721083 scopus 로고    scopus 로고
    • Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice
    • M. Fukutake, S. Nakatsugi, T. Isoi, M. Takahashi, T. Ohta, and S. Mamiya et al. Suppressive effects of nimesulide, a selective inhibitor of cyclooxygenase-2, on azoxymethane-induced colon carcinogenesis in mice Carcinogenesis 19 11 1998 1939 1942
    • (1998) Carcinogenesis , vol.19 , Issue.11 , pp. 1939-1942
    • Fukutake, M.1    Nakatsugi, S.2    Isoi, T.3    Takahashi, M.4    Ohta, T.5    Mamiya, S.6
  • 187
    • 9744251631 scopus 로고    scopus 로고
    • The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model
    • K.T. Nam, K.B. Hahm, S.Y. Oh, M. Yeo, S.U. Han, and B. Ahn et al. The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model Clin Cancer Res 10 23 2004 8105 8113
    • (2004) Clin Cancer Res , vol.10 , Issue.23 , pp. 8105-8113
    • Nam, K.T.1    Hahm, K.B.2    Oh, S.Y.3    Yeo, M.4    Han, S.U.5    Ahn, B.6
  • 188
    • 1642369791 scopus 로고    scopus 로고
    • Effect of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of lung tumors and their expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma
    • M.S. Shaik, A. Chatterjee, and M. Singh Effect of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of lung tumors and their expression of cyclooxygenase-2 and peroxisome proliferator-activated receptor-gamma Clin Cancer Res 10 4 2004 1521 1529
    • (2004) Clin Cancer Res , vol.10 , Issue.4 , pp. 1521-1529
    • Shaik, M.S.1    Chatterjee, A.2    Singh, M.3
  • 189
    • 34548709664 scopus 로고    scopus 로고
    • Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms
    • B.M. Deasy, G. O'Sullivan-Coyne, T.R. O'Donovan, S.L. McKenna, and G.C. O'Sullivan Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms Cancer Lett 256 2 2007 246 258
    • (2007) Cancer Lett , vol.256 , Issue.2 , pp. 246-258
    • Deasy, B.M.1    O'Sullivan-Coyne, G.2    O'Donovan, T.R.3    McKenna, S.L.4    O'Sullivan, G.C.5
  • 190
    • 33144485911 scopus 로고    scopus 로고
    • COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals
    • S. Han, and J. Roman COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals Lung Cancer 51 3 2006 283 296
    • (2006) Lung Cancer , vol.51 , Issue.3 , pp. 283-296
    • Han, S.1    Roman, J.2
  • 191
    • 60249094444 scopus 로고    scopus 로고
    • Nimesulide inhibits IFN-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells by COX-2 and PGE2 independent mechanisms
    • M. Liang, H. Yang, and J. Fu Nimesulide inhibits IFN-gamma-induced programmed death-1-ligand 1 surface expression in breast cancer cells by COX-2 and PGE2 independent mechanisms Cancer Lett 276 1 2009 47 52
    • (2009) Cancer Lett , vol.276 , Issue.1 , pp. 47-52
    • Liang, M.1    Yang, H.2    Fu, J.3
  • 192
    • 84867396803 scopus 로고    scopus 로고
    • SiRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions
    • K. Iwamura, T. Kato, Y. Miyahara, H. Naota, J. Mineno, and H. Ikeda et al. SiRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions Gene Ther 19 10 2012 959 966
    • (2012) Gene Ther , vol.19 , Issue.10 , pp. 959-966
    • Iwamura, K.1    Kato, T.2    Miyahara, Y.3    Naota, H.4    Mineno, J.5    Ikeda, H.6
  • 193
    • 84874107823 scopus 로고    scopus 로고
    • Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation
    • W. Hobo, T.I. Novobrantseva, H. Fredrix, J. Wong, S. Milstein, and H. Epstein-Barash et al. Improving dendritic cell vaccine immunogenicity by silencing PD-1 ligands using siRNA-lipid nanoparticles combined with antigen mRNA electroporation Cancer Immunol Immunother 62 2 2013 285 297
    • (2013) Cancer Immunol Immunother , vol.62 , Issue.2 , pp. 285-297
    • Hobo, W.1    Novobrantseva, T.I.2    Fredrix, H.3    Wong, J.4    Milstein, S.5    Epstein-Barash, H.6
  • 194
    • 78649479185 scopus 로고    scopus 로고
    • SiRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells
    • W. Hobo, F. Maas, N. Adisty, T. de Witte, N. Schaap, and R. van der Voort et al. SiRNA silencing of PD-L1 and PD-L2 on dendritic cells augments expansion and function of minor histocompatibility antigen-specific CD8+ T cells Blood 116 22 2010 4501 4511
    • (2010) Blood , vol.116 , Issue.22 , pp. 4501-4511
    • Hobo, W.1    Maas, F.2    Adisty, N.3    De Witte, T.4    Schaap, N.5    Van Der Voort, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.