-
1
-
-
0036851826
-
Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies
-
Dzau VJ, Braun-Dullaeus RC, Sedding DG, (2002) Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies. Nat Med 8: 1249-1256.
-
(2002)
Nat Med
, vol.8
, pp. 1249-1256
-
-
Dzau, V.J.1
Braun-Dullaeus, R.C.2
Sedding, D.G.3
-
2
-
-
0033870765
-
Vascular cell apoptosis in remodeling, restenosis, and plaque rupture
-
Walsh K, Smith RC, Kim HS, (2000) Vascular cell apoptosis in remodeling, restenosis, and plaque rupture. Circ Res 87: 184-188.
-
(2000)
Circ Res
, vol.87
, pp. 184-188
-
-
Walsh, K.1
Smith, R.C.2
Kim, H.S.3
-
3
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama T, Dixon JE, (1998) The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem 273: 13375-13378.
-
(1998)
J Biol Chem
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
4
-
-
0032431032
-
The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway
-
Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL, (1998) The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway. Proc Natl Acad Sci U S A 95: 15587-15591.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15587-15591
-
-
Wu, X.1
Senechal, K.2
Neshat, M.S.3
Whang, Y.E.4
Sawyers, C.L.5
-
5
-
-
0036094861
-
Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN
-
Huang J, Kontos CD, (2002) Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN. Arterioscler Thromb Vasc Biol 22: 745-751.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 745-751
-
-
Huang, J.1
Kontos, C.D.2
-
6
-
-
13244297003
-
Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia
-
Huang J, Niu XL, Pippen AM, Annex BH, Kontos CD, (2005) Adenovirus-mediated intraarterial delivery of PTEN inhibits neointimal hyperplasia. Arterioscler Thromb Vasc Biol 25: 354-358.
-
(2005)
Arterioscler Thromb Vasc Biol
, vol.25
, pp. 354-358
-
-
Huang, J.1
Niu, X.L.2
Pippen, A.M.3
Annex, B.H.4
Kontos, C.D.5
-
7
-
-
0031870959
-
Pten is essential for embryonic development and tumour suppression
-
Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP, (1998) Pten is essential for embryonic development and tumour suppression. Nat Genet 19: 348-355.
-
(1998)
Nat Genet
, vol.19
, pp. 348-355
-
-
Di Cristofano, A.1
Pesce, B.2
Cordon-Cardo, C.3
Pandolfi, P.P.4
-
8
-
-
79957447572
-
SDF-1alpha induction in mature smooth muscle cells by inactivation of PTEN is a critical mediator of exacerbated injury-induced neointima formation
-
Nemenoff RA, Horita H, Ostriker AC, Furgeson SB, Simpson PA, et al. SDF-1alpha induction in mature smooth muscle cells by inactivation of PTEN is a critical mediator of exacerbated injury-induced neointima formation. Arterioscler Thromb Vasc Biol 31: 1300-1308.
-
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1300-1308
-
-
Nemenoff, R.A.1
Horita, H.2
Ostriker, A.C.3
Furgeson, S.B.4
Simpson, P.A.5
-
9
-
-
0032719663
-
A novel role for the cyclin-dependent kinase inhibitor p27KIP1 in angiotensin II-stimulated vascular smooth muscle cell hypertrophy
-
Braun-Dullaeus RC, Mann MJ, Ziegler A, von der Leyen HE, Dzau VJ, (1999) A novel role for the cyclin-dependent kinase inhibitor p27KIP1 in angiotensin II-stimulated vascular smooth muscle cell hypertrophy. J Clin Invest 104: 815-823.
-
(1999)
J Clin Invest
, vol.104
, pp. 815-823
-
-
Braun-Dullaeus, R.C.1
Mann, M.J.2
Ziegler, A.3
von der Leyen, H.E.4
Dzau, V.J.5
-
10
-
-
38949127599
-
Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo
-
Sedding DG, Homann M, Seay U, Tillmanns H, Preissner KT, et al. (2008) Calpain counteracts mechanosensitive apoptosis of vascular smooth muscle cells in vitro and in vivo. Faseb J 22: 579-589.
-
(2008)
Faseb J
, vol.22
, pp. 579-589
-
-
Sedding, D.G.1
Homann, M.2
Seay, U.3
Tillmanns, H.4
Preissner, K.T.5
-
11
-
-
0022568961
-
Expression of smooth muscle-specific alpha-isoactin in cultured vascular smooth muscle cells: relationship between growth and cytodifferentiation
-
Owens GK, Loeb A, Gordon D, Thompson MM, (1986) Expression of smooth muscle-specific alpha-isoactin in cultured vascular smooth muscle cells: relationship between growth and cytodifferentiation. J Cell Biol 102: 343-352.
-
(1986)
J Cell Biol
, vol.102
, pp. 343-352
-
-
Owens, G.K.1
Loeb, A.2
Gordon, D.3
Thompson, M.M.4
-
12
-
-
20444372545
-
Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation
-
Connor KM, Subbaram S, Regan KJ, Nelson KK, Mazurkiewicz JE, et al. (2005) Mitochondrial H2O2 regulates the angiogenic phenotype via PTEN oxidation. The Journal of biological chemistry 280: 16916-16924.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 16916-16924
-
-
Connor, K.M.1
Subbaram, S.2
Regan, K.J.3
Nelson, K.K.4
Mazurkiewicz, J.E.5
-
13
-
-
0033886373
-
Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling
-
Irani K, (2000) Oxidant signaling in vascular cell growth, death, and survival: a review of the roles of reactive oxygen species in smooth muscle and endothelial cell mitogenic and apoptotic signaling. Circ Res 87: 179-183.
-
(2000)
Circ Res
, vol.87
, pp. 179-183
-
-
Irani, K.1
-
14
-
-
0033604585
-
The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
-
Kandel ES, Hay N, (1999) The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 253: 210-229.
-
(1999)
Exp Cell Res
, vol.253
, pp. 210-229
-
-
Kandel, E.S.1
Hay, N.2
-
15
-
-
0031042525
-
Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury
-
Perlman H, Maillard L, Krasinski K, Walsh K, (1997) Evidence for the rapid onset of apoptosis in medial smooth muscle cells after balloon injury. Circulation 95: 981-987.
-
(1997)
Circulation
, vol.95
, pp. 981-987
-
-
Perlman, H.1
Maillard, L.2
Krasinski, K.3
Walsh, K.4
-
16
-
-
77956935917
-
Upregulation of PTEN by peroxynitrite contributes to cytokine-induced apoptosis in pancreatic beta-cells
-
Hou R, Zhang J, Yin T, Cao H, Zhang N, et al. (2010) Upregulation of PTEN by peroxynitrite contributes to cytokine-induced apoptosis in pancreatic beta-cells. Apoptosis 15: 877-886.
-
(2010)
Apoptosis
, vol.15
, pp. 877-886
-
-
Hou, R.1
Zhang, J.2
Yin, T.3
Cao, H.4
Zhang, N.5
-
17
-
-
34848892187
-
Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner
-
Song P, Wu Y, Xu J, Xie Z, Dong Y, et al. (2007) Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner. Circulation 116: 1585-1595.
-
(2007)
Circulation
, vol.116
, pp. 1585-1595
-
-
Song, P.1
Wu, Y.2
Xu, J.3
Xie, Z.4
Dong, Y.5
-
18
-
-
34748820655
-
Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway
-
Cesaratto L, Calligaris SD, Vascotto C, Deganuto M, Bellarosa C, et al. (2007) Bilirubin-induced cell toxicity involves PTEN activation through an APE1/Ref-1-dependent pathway. J Mol Med 85: 1099-1112.
-
(2007)
J Mol Med
, vol.85
, pp. 1099-1112
-
-
Cesaratto, L.1
Calligaris, S.D.2
Vascotto, C.3
Deganuto, M.4
Bellarosa, C.5
-
19
-
-
0032717640
-
New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury
-
Santiago FS, Lowe HC, Kavurma MM, Chesterman CN, Baker A, et al. (1999) New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury. Nature medicine 5: 1264-1269.
-
(1999)
Nature Medicine
, vol.5
, pp. 1264-1269
-
-
Santiago, F.S.1
Lowe, H.C.2
Kavurma, M.M.3
Chesterman, C.N.4
Baker, A.5
-
20
-
-
20144386738
-
Cross-regulation between Egr-1 and APE/Ref-1 during early response to oxidative stress in the human osteoblastic HOBIT cell line: evidence for an autoregulatory loop
-
Pines A, Bivi N, Romanello M, Damante G, Kelley MR, et al. (2005) Cross-regulation between Egr-1 and APE/Ref-1 during early response to oxidative stress in the human osteoblastic HOBIT cell line: evidence for an autoregulatory loop. Free Radic Res 39: 269-281.
-
(2005)
Free Radic Res
, vol.39
, pp. 269-281
-
-
Pines, A.1
Bivi, N.2
Romanello, M.3
Damante, G.4
Kelley, M.R.5
-
21
-
-
0142137134
-
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
-
Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, et al. (2003) Redox regulation of PI 3-kinase signalling via inactivation of PTEN. The EMBO journal 22: 5501-5510.
-
(2003)
The EMBO Journal
, vol.22
, pp. 5501-5510
-
-
Leslie, N.R.1
Bennett, D.2
Lindsay, Y.E.3
Stewart, H.4
Gray, A.5
-
22
-
-
11144279346
-
The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway
-
Seo JH, Ahn Y, Lee SR, Yeol Yeo C, Chung Hur K, (2005) The major target of the endogenously generated reactive oxygen species in response to insulin stimulation is phosphatase and tensin homolog and not phosphoinositide-3 kinase (PI-3 kinase) in the PI-3 kinase/Akt pathway. Molecular biology of the cell 16: 348-357.
-
(2005)
Molecular Biology of the Cell
, vol.16
, pp. 348-357
-
-
Seo, J.H.1
Ahn, Y.2
Lee, S.R.3
Yeol Yeo, C.4
Chung Hur, K.5
-
23
-
-
0031042222
-
Reactive oxygen species induce apoptosis of vascular smooth muscle cell
-
Li PF, Dietz R, von Harsdorf R, (1997) Reactive oxygen species induce apoptosis of vascular smooth muscle cell. FEBS Lett 404: 249-252.
-
(1997)
FEBS Lett
, vol.404
, pp. 249-252
-
-
Li, P.F.1
Dietz, R.2
von Harsdorf, R.3
-
24
-
-
0034733776
-
Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerotic factors
-
Dimmeler S, Zeiher AM, (2000) Reactive oxygen species and vascular cell apoptosis in response to angiotensin II and pro-atherosclerotic factors. Regul Pept 90: 19-25.
-
(2000)
Regul Pept
, vol.90
, pp. 19-25
-
-
Dimmeler, S.1
Zeiher, A.M.2
-
25
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC, (2002) The phosphoinositide 3-kinase pathway. Science 296: 1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
26
-
-
0042413919
-
Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells
-
Sedding DG, Seay U, Fink L, Heil M, Kummer W, et al. (2003) Mechanosensitive p27Kip1 regulation and cell cycle entry in vascular smooth muscle cells. Circulation 108: 616-622.
-
(2003)
Circulation
, vol.108
, pp. 616-622
-
-
Sedding, D.G.1
Seay, U.2
Fink, L.3
Heil, M.4
Kummer, W.5
-
27
-
-
34447527440
-
PTEN reduces cuff-induced neointima formation and proinflammatory cytokines
-
Koide S, Okazaki M, Tamura M, Ozumi K, Takatsu H, et al. (2007) PTEN reduces cuff-induced neointima formation and proinflammatory cytokines. Am J Physiol Heart Circ Physiol 292: H2824-2831.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
-
-
Koide, S.1
Okazaki, M.2
Tamura, M.3
Ozumi, K.4
Takatsu, H.5
-
28
-
-
43449083502
-
Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha
-
Nemenoff RA, Simpson PA, Furgeson SB, Kaplan-Albuquerque N, Crossno J, et al. (2008) Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha. Circ Res 102: 1036-1045.
-
(2008)
Circ Res
, vol.102
, pp. 1036-1045
-
-
Nemenoff, R.A.1
Simpson, P.A.2
Furgeson, S.B.3
Kaplan-Albuquerque, N.4
Crossno, J.5
-
29
-
-
77951696279
-
Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation
-
Furgeson SB, Simpson PA, Park I, Vanputten V, Horita H, et al. (2010) Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation. Cardiovasc Res 86: 274-282.
-
(2010)
Cardiovasc Res
, vol.86
, pp. 274-282
-
-
Furgeson, S.B.1
Simpson, P.A.2
Park, I.3
Vanputten, V.4
Horita, H.5
-
30
-
-
0029113373
-
Evidence for apoptosis in human atherogenesis and in a rat vascular injury model
-
Han DK, Haudenschild CC, Hong MK, Tinkle BT, Leon MB, et al. (1995) Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am J Pathol 147: 267-277.
-
(1995)
Am J Pathol
, vol.147
, pp. 267-277
-
-
Han, D.K.1
Haudenschild, C.C.2
Hong, M.K.3
Tinkle, B.T.4
Leon, M.B.5
-
31
-
-
0028997321
-
Apoptosis participates in cellularity regulation during rat aortic intimal thickening
-
Bochaton-Piallat ML, Gabbiani F, Redard M, Desmouliere A, Gabbiani G, (1995) Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am J Pathol 146: 1059-1064.
-
(1995)
Am J Pathol
, vol.146
, pp. 1059-1064
-
-
Bochaton-Piallat, M.L.1
Gabbiani, F.2
Redard, M.3
Desmouliere, A.4
Gabbiani, G.5
-
32
-
-
84869473350
-
Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells
-
Dong X, Yu LG, Sun R, Cheng YN, Cao H, et al. (2012) Inhibition of PTEN expression and activity by angiotensin II induces proliferation and migration of vascular smooth muscle cells. Journal of cellular biochemistry.
-
(2012)
Journal of Cellular Biochemistry
-
-
Dong, X.1
Yu, L.G.2
Sun, R.3
Cheng, Y.N.4
Cao, H.5
|