Costunolide and Dehydrocostuslactone, two natural sesquiterpene lactones, ameliorate the inflammatory process associated to experimental pleurisy in mice

European Journal of Pharmacology

Volumn 730, Issue 1, 2014, Pages 107-115

  Butturini, Elena ^a   Di Paola, Rosanna ^b   Suzuki, Hisanori ^a   Paterniti, Irene ^b   Ahmad, Akbar ^b   Mariotto, Sofia ^a   Cuzzocrea, Salvatore ^b,c  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Costunolide; Dehydrocostuslactone; Inflammation; NF B; Peroxynitrite; STAT3

Indexed keywords

3 NITROTYROSINE; CARRAGEENAN; COSTUNOLIDE; DEHYDROCOSTUSLACTONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); SESQUITERPENE LACTONE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 3-NITROTYROSINE; ANTIINFLAMMATORY AGENT; DEHYDROCOSTUS LACTONE; LACTONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PARP1 PROTEIN, MOUSE; SESQUITERPENE; TYROSINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; EXPERIMENTAL PLEURISY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY DISEASE; LUNG PARENCHYMA; MALE; MOUSE; NONHUMAN; PLEURA CAVITY; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; UPREGULATION; ACUTE LUNG INJURY; ANALOGS AND DERIVATIVES; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DISEASE MODEL; METABOLISM; PLEURISY;

ACUTE LUNG INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; DISEASE MODELS, ANIMAL; LACTONES; MALE; MICE; NF-KAPPA B; PLEURISY; POLY(ADP-RIBOSE) POLYMERASES; SESQUITERPENES; STAT3 TRANSCRIPTION FACTOR; TYROSINE;

EID: 84896552191     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.02.031     Document Type: Article

References (34)

1. A.S. Baldwin Jr. Series introduction: the transcription factor NF-kappaB and human disease J. Clin. Invest. 107 2001 3 6
2. E. Butturini, A. Carcereri de Prati, G. Chiavegato, A. Rigo, E. Cavalieri, E. Darra, and S. Mariotto Mild oxidative stress induces S-glutathionylation of STAT3 and enhances chemosensitivity of tumoural cells to chemotherapeutic drugs Free Radic. Biol. Med. 65C 2013 1322 1330
3. E. Butturini, E. Cavalieri, A.C. de Prati, E. Darra, A. Rigo, K. Shoji, N. Murayama, H. Yamazaki, Y. Watanabe, H. Suzuki, and S. Mariotto Two naturally occurring terpenes, dehydrocostuslactone and costunolide, decrease intracellular GSH content and inhibit STAT3 activation PLoS One 6 2011 e20174
4. M. Campolo, R. Di Paola, D. Impellizzeri, R. Crupi, V.M. Morittu, A. Procopio, E. Perri, D. Britti, A. Peli, E. Esposito, and S. Cuzzocrea Effects of a polyphenol present in olive oil, oleuropein aglycone, in a murine model of intestinal ischemia/reperfusion injury J. Leukocyte Biol. 93 2013 277 287
5. S. Cuzzocrea, G. de Sarro, G. Costantino, E. Mazzon, R. Laura, E. Ciriaco, A. de Sarro, and A.P Caputi Role of interleukin-6 in a non-septic shock model induced by zymosan Eur. Cytokine Netw. 10 1999 191 203 (Pubitemid 29332775)
6. S. Cuzzocrea, E. Mazzon, G. Calabro, L. Dugo, A. De Sarro, L.F. van De, and A.P. Caputi Inducible nitric oxide synthase-knockout mice exhibit resistance to pleurisy and lung injury caused by carrageenan Am. J. Respir. Crit. Care Med. 162 2000 1859 1866
7. S. Cuzzocrea, B. Pisano, L. Dugo, A. Ianaro, N.S. Patel, A.P. Caputi, and C. Thiemermann Tempol reduces the activation of nuclear factor-kappaB in acute inflammation Free Radic. Res. 38 2004 813 819 (Pubitemid 39077368)
8. S. Cuzzocrea, L. Sautebin, G. De Sarro, G. Costantino, L. Rombola, E. Mazzon, A. Ialenti, A. De Sarro, G. Ciliberto, M. Di Rosa, A.P. Caputi, and C. Thiemermann Role of IL-6 in the pleurisy and lung injury caused by carrageenan J. Immunol. 163 1999 5094 5104 (Pubitemid 29501279)
9. S. Cuzzocrea, B. Zingarelli, G. Costantino, and A.P. Caputi Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-induced pleurisy Free Radic. Biol. Med. 26 1999 25 33 (Pubitemid 29001490)
10. J.E. Darnell Jr., I.M. Kerr, and G.R. Stark Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins Science 264 1994 1415 1421 (Pubitemid 24217131)
11. L. Fialkow, Y. Wang, and G.P. Downey Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function Free Radic. Biol. Med. 42 2007 153 164 (Pubitemid 46001554)
12. H. Gao, R.F. Guo, C.L. Speyer, J. Reuben, T.A. Neff, L.M. Hoesel, N.C. Riedemann, S.D. McClintock, J.V. Sarma, N. Van Rooijen, F.S. Zetoune, and P.A. Ward Stat3 activation in acute lung injury J. Immunol. 172 2004 7703 7712 (Pubitemid 38747637)
13. T. Genovese, E. Mazzon, R. Di Paola, C. Muia, M.D. Threadgill, A.P. Caputi, C. Thiemermann, and S. Cuzzocrea Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury J. Pharmacol. Exp. Ther. 313 2005 529 538 (Pubitemid 40604151)
14. Y.L. Hsu, L.Y. Wu, and P.L. Kuo Dehydrocostuslactone, a medicinal plant-derived sesquiterpene lactone, induces apoptosis coupled to endoplasmic reticulum stress in liver cancer cells J. Pharmacol. Exp. Ther. 329 2009 808 819
15. J.Y. Hung, Y.L. Hsu, W.C. Ni, Y.M. Tsai, C.J. Yang, P.L. Kuo, and M.S. Huang Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells Lung Cancer 68 2010 355 365
16. T.H. Koo, J.H. Lee, Y.J. Park, Y.S. Hong, H.S. Kim, K.W. Kim, and J.J. Lee A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kappa B by targeting I kappa B phosphorylation Planta Med. 67 2001 103 107
17. P.L. Kuo, W.C. Ni, E.M. Tsai, and Y.L. Hsu Dehydrocostuslactone disrupts signal transducers and activators of transcription 3 through up-regulation of suppressor of cytokine signaling in breast cancer cells Mol. Cancer Ther. 8 2009 1328 1339
18. Y. Liu, X.Q. Chen, H.X. Liang, F.X. Zhang, B. Zhang, J. Jin, Y.L. Chen, Y.X. Cheng, and G.B. Zhou Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myeloma PLoS One 6 2011 e21930
19. S. Mariotto, E. Esposito, R. Di Paola, A. Ciampa, E. Mazzon, A.C. de Prati, E. Darra, S. Vincenzi, G. Cucinotta, R. Caminiti, H. Suzuki, and S. Cuzzocrea Protective effect of Arbutus unedo aqueous extract in carrageenan-induced lung inflammation in mice Pharmacol. Res. 57 2008 110 124
20. M. Menegazzi, R. Di Paola, E. Mazzon, T. Genovese, C. Crisafulli, M. Dal Bosco, Z. Zou, H. Suzuki, and S. Cuzzocrea Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice Pharmacol. Res. 58 2008 22 31
21. M. Menegazzi, M. Novelli, P. Beffy, V. D'Aleo, E. Tedeschi, R. Lupi, E. Zoratti, P. Marchetti, H. Suzuki, and P. Masiello Protective effects of St. John× wort extract and its component hyperforin against cytokine-induced cytotoxicity in a pancreatic beta-cell line Int. J. Biochem. Cell Biol. 40 2008 1509 1521
22. S. Mukhopadhyay, J.R. Hoidal, and T.K. Mukherjee Role of TNFalpha in pulmonary pathophysiology Respir. Res. 7 2006 125
23. K.M. Mullane, R. Kraemer, and B. Smith Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium J. Pharmacol. Methods 14 1985 157 167 (Pubitemid 15241170)
24. H. Nakazawa, N. Fukuyama, S. Takizawa, C. Tsuji, M. Yoshitake, and H. Ishida Nitrotyrosine formation and its role in various pathological conditions Free Radic. Res. 33 2000 771 784 (Pubitemid 32208485)
25. F. Nantel, D. Denis, R. Gordon, A. Northey, M. Cirino, K.M. Metters, and C.C. Chan Distribution and regulation of cyclooxygenase-2 in carrageenan-induced inflammation Br. J. Pharmacol. 128 1999 853 859 (Pubitemid 29494701)
26. H.O. Pae, G.S. Jeong, H.S. Kim, W.H. Woo, H.Y. Rhew, D.H. Sohn, Y.C. Kim, and H.T. Chung Costunolide inhibits production of tumor necrosis factor-alpha and interleukin-6 by inducing heme oxygenase-1 in RAW264.7 macrophages Inflamm. Res. 56 2007 520 526
27. H.J. Park, S.H. Kwon, Y.N. Han, J.W. Choi, K. Miyamoto, S.H. Lee, and K.T. Lee Apoptosis-Inducing costunolide and a novel acyclic monoterpene from the stem bark of Magnolia sieboldii Arch. Pharmacal Res. 24 2001 342 348
28. R.T. Peters, S.M. Liao, and T. Maniatis IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex Mol. Cell. 5 2000 513 522
29. E. Pfitzner, S. Kliem, D. Baus, and C.M. Litterst The role of STATs in inflammation and inflammatory diseases Curr. Pharm. Des. 10 2004 2839 2850 (Pubitemid 39162402)
30. M. Robles, M. Aregullin, J. West, and E. Rodriguez Recent studies on the zoopharmacognosy, pharmacology and neurotoxicology of sesquiterpene lactones Planta Med. 61 1995 199 203
31. D. Salvemini, E. Mazzon, L. Dugo, D.P. Riley, I. Serraino, A.P. Caputi, and S. Cuzzocrea Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403 Br. J. Pharmacol. 132 2001 815 827 (Pubitemid 32193638)
32. R. Sobota, M. Szwed, A. Kasza, M. Bugno, and T. Kordula Parthenolide inhibits activation of signal transducers and activators of transcription (STATs) induced by cytokines of the IL-6 family Biochem. Biophys. Res. Commun. 267 2000 329 333 (Pubitemid 30072551)
33. L. Virag Poly(ADP-ribosyl)ation in asthma and other lung diseases Pharmacol. Res. 52 2005 83 92 (Pubitemid 40725602)
34. T.H. Wyman, A.J. Bjornsen, D.J. Elzi, C.W. Smith, K.M. England, M. Kelher, and C.C. Silliman A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release Am. J. Physiol.: Cell Physiol. 283 2002 C1592 C1603