Nitrotyrosine formation and its role in various pathological conditions

Free Radical Research

Volumn 33, Issue 6, 2000, Pages 771-784

  Nakazawa, H ^a   Fukuyama, N ^a   Takizawa, S ^a   Tsuji, C ^a   Yoshitake, M ^a   Ishida, H ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Ischemia reperfusion; Nitrotyrosine; Polymorphonuclear leukocyte; Radiation injury; Superoxide

Indexed keywords

3 NITROTYROSINE; AMINOGUANIDINE; CYTOKINE; INTERLEUKIN 1BETA; NITRIC OXIDE; PEROXYNITRITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL ACTIVATION; CELL DAMAGE; CONTROLLED STUDY; DEGRADATION; DISEASE SEVERITY; DOG; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG INJURY; MALE; MEDIATOR; MYOCARDIAL DISEASE; NONHUMAN; PATHOLOGY; POLYMORPHONUCLEAR CELL; RADIATION INJURY; RAT; REPERFUSION INJURY; TIME; TISSUE INJURY;

ANIMALIA; CANIS FAMILIARIS;

EID: 0034468695     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760000301291     Document Type: Article

References (41)

1. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
2. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
3. Protective effects of inhibitors of nitric oxide synthase in immune complex-induced vasculitis
4. Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures
5. Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide
6. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide
7. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase
8. ALS, SOD and peroxynitrite
9. Peroxynitrite-induced membrane lipid peroxidation: The cytotoxic potential of superoxide and nitric oxide
10. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
11. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
12. Peroxynitrite formation in focal cerebral ischemia-reperfusion in rats occurs predominantly in the peri-infarct region
13. Evidence for nitric oxide-mediated oxidative damage in chronic inflammation. Nitrotyrosine in serum and synovial fluid from rheumatoid patients
14. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry
15. Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury
16. Peroxynitrite is not a major mediator of endothelial cell injury by activated neutrophils in vitro
17. Peroxynitrite formation from activated human leukocytes
18. Peroxynitrite-induced cardiac my ocyte injury
19. Isolation and culture of pulmonary artery endothelial cells
20. Inflammation and NO(X)-induced nitration: Assay for 3-nitrotyrosine by HPLC with electrochemical detection
21. Identification of N-iminoethyl-L-ornithine as an irreversible inhibitor of nitric oxide synthase in phagocytic cells
22. Endogenous peroxynitrite is involved in the inhibition of mitochondrial respiration in immuno-stimulated J774.2 macrophages
23. Nitric oxide prevents leukocyte adherence: Role of superoxide
24. Nitric oxide: An endogenous modulator of leukocyte adhesion
25. Dynamics of nitrotyrosine formation and decay in rat brain during focal ischemia-reperfusion
26. Role of superoxide anion in the pathogenesis of cytokine-induced myocardial dysfunction in dogs in vivo
27. Effects of superoxide dismutase on nitric oxide production during reperfusion after focal cerebral ischemia is rats
28. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
29. Nitric oxide measured by a porphyrinic microsensor in rat brain after transient middle cerebral artery occlusion
30. The reaction of NO. with O2.- and HO2.: A pulse radiolysis study
31. The reaction of no with superoxide
32. An activity in rat tissues that modifies nitrotyrosine-containing proteins
33. Formation and loss of nitrated proteins in peroxynitrite-treated rat skin in vivo
34. Denitration of peroxynitrite-treated proteins by "protein nitratases" from dog prostate
35. Increased production of nitrotyrosine in lung tissue of rats with radiation-induced acute lung injury
36. Local production of interleukin-4 during radiation-induced pneumonitis and pulmonary fibrosis in rats: Macrophages as a prominent source of interleukin-4
37. Expression of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 on alveolar macrophages in the acute stage of radiation-induced lung injury in rats
38. Nitric oxide as an inflammatory mediator of radiation pneumonitis in rats
39. Release of interleukin-1 by human alveolar macrophages after in vitro irradiation
40. Role of nitric oxide and peroxynitrite in the cytokine-induced sustained myocardial dysfunction in dogs in vivo
41. Cytokine-inducible nitric oxide synthase (iNOS) expression in cardiac myocytes. Characterization and regulation of iNOS expression and detection of iNOS activity in single cardiac myocytes in vitro